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chlordiazepoxide and Ataxia

chlordiazepoxide has been researched along with Ataxia in 21 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Ataxia: Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.

Research Excerpts

ExcerptRelevanceReference
"Four groups of rats received chlordiazepoxide (CDP): a) intermittently, experiencing hypothermia and rotarod performance (RR) deficit after test doses (contingency); b) chronically, experiencing hypothermia and RR deficit after test doses; c) intermittently, RR preceding test doses and with protection against hypothermia afforded by exposure to heat lamps (nonexperienced, noncontingency); and d) chronically, RR preceding test doses and with protection against hypothermia."7.68Cellular and learned tolerances to chlordiazepoxide hypothermia and ataxia. ( MacKenzie-Taylor, DR; Rech, RH, 1993)
"Four groups of rats received chlordiazepoxide (CDP): a) intermittently, experiencing hypothermia and rotarod performance (RR) deficit after test doses (contingency); b) chronically, experiencing hypothermia and RR deficit after test doses; c) intermittently, RR preceding test doses and with protection against hypothermia afforded by exposure to heat lamps (nonexperienced, noncontingency); and d) chronically, RR preceding test doses and with protection against hypothermia."3.68Cellular and learned tolerances to chlordiazepoxide hypothermia and ataxia. ( MacKenzie-Taylor, DR; Rech, RH, 1993)
" Tolerance was evaluated by constructing dose-response curves to CDP following chronic administration of either CDP or saline."1.29Differential regulation of the behavioral effects of chlordiazepoxide. ( Lucki, I; Shumsky, JS, 1994)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199017 (80.95)18.7374
1990's3 (14.29)18.2507
2000's1 (4.76)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McElroy, JF1
Ward, KA1
Zeller, KL1
Jones, KW1
Gilligan, PJ1
He, L1
Lelas, S1
KRAUTHAMMER, W2
WARICK, LH1
BARROWS, HS1
SPARK, H1
GOLDMAN, AS1
KOKENGE, R1
KUTT, H1
MCDOWELL, F1
Stark, P2
Dews, PB1
Shumsky, JS1
Lucki, I1
MacKenzie-Taylor, DR1
Rech, RH1
Vanover, KE1
Vyden, JK1
Curnow, DH1
Beck, AB1
Boundy, CA1
Barnett, A1
Taber, RI1
Steiner, SS1
Brittain, RT1
Plotnikoff, N1
Will, F1
Ditzler, W1
Goldstein, DB1
Barzaghi, F1
Fournex, R1
Mantegazza, P1
Kerry, RJ1
McDermott, CM1
Orme, JE1
Critchley, E1
Pifferi, G1
Consonni, P1
Banfi, S1
Diena, A1
Daly, RJ1
Kane, FJ1
Henderson, JK1

Other Studies

21 other studies available for chlordiazepoxide and Ataxia

ArticleYear
The CRF(1) receptor antagonist DMP696 produces anxiolytic effects and inhibits the stress-induced hypothalamic-pituitary-adrenal axis activation without sedation or ataxia in rats.
    Psychopharmacology, 2002, Volume: 165, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Anxiety; Ataxia; Behavior, Animal; Chlord

2002
[OVERDISAGE OF DRUGS (LIBRIUM) IN SMALL CHILDREN AND POSSIBILITIES OF EEG DIAGNOSIS IN ALLEGED DRUG OVERDOSAGE].
    Schweizerische medizinische Wochenschrift, 1963, Nov-16, Volume: 93

    Topics: Ataxia; Child; Chlordiazepoxide; Diagnosis, Differential; Electroencephalography; Epilepsy; Infant;

1963
[OVERDOSAGE OF DRUGS (LIBRIUM) IN SMALL CHILDREN AND POSSIBILITIES OF EEG DIAGNOSIS IN ALLEGED DRUG OVERDOSAGE].
    Schweizerische medizinische Wochenschrift, 1963, Nov-16, Volume: 93

    Topics: Ataxia; Child; Chlordiazepoxide; Diagnosis, Differential; Electroencephalography; Epilepsy; Infant;

1963
TREATMENT OF HUNTINGTON'S CHOREA WITH CHLORDIAZEPOXIDE (LIBRIUM).
    Bulletin of the Los Angeles Neurological Society, 1964, Volume: 29

    Topics: Ataxia; Black People; Chlordiazepoxide; Chorea; Geriatrics; Huntington Disease; Meprobamate; Reserpi

1964
DIAZEPAM INTOXICATION IN A CHILD.
    American journal of diseases of children (1960), 1965, Volume: 109

    Topics: Ataxia; Child; Chlordiazepoxide; Diazepam; Electroencephalography; Metabolism; Poisoning; Sleep Wake

1965
NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
    Neurology, 1965, Volume: 15

    Topics: Adolescent; Ataxia; Biomedical Research; Cats; Chlordiazepoxide; Drug Therapy; Epilepsy; Humans; Neu

1965
Cannabinoids. I. Behavioral effects.
    The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1

    Topics: Animals; Ataxia; Behavior, Animal; Cannabinoids; Chlordiazepoxide; Conditioning, Psychological; Dogs

1980
Differential regulation of the behavioral effects of chlordiazepoxide.
    Psychopharmacology, 1994, Volume: 115, Issue:1-2

    Topics: Amnesia; Animals; Ataxia; Avoidance Learning; Behavior, Animal; Body Temperature; Chlordiazepoxide;

1994
Cellular and learned tolerances to chlordiazepoxide hypothermia and ataxia.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 44, Issue:3

    Topics: Animals; Ataxia; Body Temperature; Chlordiazepoxide; Drug Tolerance; Hypothermia; Learning; Male; Pe

1993
Interaction of ethanol with excitatory amino acid receptor antagonists in mice.
    European journal of pharmacology, 1999, Mar-05, Volume: 368, Issue:2-3

    Topics: Animals; Ataxia; Behavior, Animal; Benzodiazepines; Central Nervous System Depressants; Chlordiazepo

1999
Failure of chlordiazepoxide to influence urinary copper excretion.
    Lancet (London, England), 1972, Nov-18, Volume: 2, Issue:7786

    Topics: Adult; Ataxia; Chlordiazepoxide; Copper; Humans; Male

1972
The behavioral pharmacology of Sch 12679. A new psychoactive agent.
    Psychopharmacologia, 1974, May-15, Volume: 36, Issue:4

    Topics: Aggression; Animals; Ataxia; Avoidance Learning; Benzazepines; Chemical Phenomena; Chemistry; Chlord

1974
The intracerebral effects of noradrenaline and its modification by drugs in the mouse.
    The Journal of pharmacy and pharmacology, 1966, Volume: 18, Issue:9

    Topics: Amitriptyline; Animals; Antidepressive Agents; Ataxia; Atropine; Body Temperature; Brain; Central Ne

1966
Stimulant activity of pemoline and magnesium hydroxide.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 181, Issue:2

    Topics: Animals; Antacids; Ataxia; Caffeine; Cats; Central Nervous System Stimulants; Chlordiazepoxide; Chlo

1969
An animal model for testing effects of drugs on alcohol withdrawal reactions.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 183, Issue:1

    Topics: Animals; Ataxia; Barbiturates; Chlordiazepoxide; Chlormethiazole; Diazepam; Ethanol; Humans; Male; M

1972
Pharmacological and toxicological properties of clobazam (1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-diketo-3H-1,5-benzodiazepine), a new psychotherapeutic agent.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:5

    Topics: Aggression; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Benzazepines; Cats; Chemical Phenome

1973
Bromazepam, medazepam, chlordiazepoxide in treatment of neurotic anxiety.
    The British journal of psychiatry : the journal of mental science, 1974, Volume: 124, Issue:0

    Topics: Adult; Anxiety Disorders; Ataxia; Benzazepines; Benzene Derivatives; Benzodiazepinones; Chlordiazepo

1974
Clinical manifestations of essential tremor.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:3

    Topics: Adult; Aged; Amantadine; Ataxia; Chlordiazepoxide; Dihydroxyphenylalanine; Female; Humans; Male; Mep

1972
2,3-benzoxazines. IX. Synthesis and central nervous system depressant activity of some 3,6- and 3,7-disubstituted 1H-3,4-dihydro-2,3-benzoxazines.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:2

    Topics: Analgesia; Animals; Aspirin; Ataxia; Barbiturates; Central Nervous System; Chlordiazepoxide; Chlorpr

1969
Two severe reactions to benzodiazepine compounds.
    The American journal of psychiatry, 1965, Volume: 122, Issue:5

    Topics: Adult; Alcoholism; Ataxia; Chlordiazepoxide; Diazepam; Drug Synergism; Humans; Male; Middle Aged; Mu

1965
Differentiation of classes of neurosedatives using rats with septal lesions.
    International journal of neuropharmacology, 1966, Volume: 5, Issue:6

    Topics: Amobarbital; Animals; Ataxia; Behavior, Animal; Cerebral Ventricles; Chlordiazepoxide; Chlorpromazin

1966