chlordiazepoxide has been researched along with Aging in 13 studies
Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Absolute bioavailability of oral chlordiazepoxide was not less than 100%, and was unrelated to age or sex." | 1.28 | Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition. ( Abernethy, DR; Divoll, MK; Greenblatt, DJ; Harmatz, JS; Ochs, HR; Shader, RI, 1989) |
| "The diazepam stimuli were dose-dependent in each group." | 1.27 | A comparison of diazepam stimuli in aged and adult rats. ( Amrick, CL; Bennett, DA, 1987) |
| "The elimination half-life of chlordiazepoxide and diazepam increases with age, and this may cause prolongation of action after a single dose and delayed accumulation on multiple dosing in elderly patients." | 1.26 | [Pharmacokinetic of benzodiazepines in old age]. ( Vozeh, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (69.23) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vozeh, S | 1 |
| Abbracchio, MP | 1 |
| Balduini, W | 1 |
| Coen, E | 1 |
| Lombardelli, G | 1 |
| Peruzzi, G | 1 |
| Cattabeni, F | 1 |
| McGaughy, J | 2 |
| Sarter, M | 4 |
| Turchi, J | 1 |
| Holley, LA | 1 |
| Hoyumpa, AM | 1 |
| Schenker, S | 1 |
| Wilkinson, GR | 1 |
| Moore, H | 1 |
| Bruno, JP | 1 |
| Greenblatt, DJ | 1 |
| Divoll, MK | 1 |
| Abernethy, DR | 1 |
| Ochs, HR | 1 |
| Harmatz, JS | 1 |
| Shader, RI | 1 |
| Amrick, CL | 1 |
| Bennett, DA | 1 |
| Bourgoin, S | 1 |
| Faivre-Bauman, A | 1 |
| Benda, P | 1 |
| Glowinski, J | 1 |
| Hamon, M | 1 |
| Sainz, A | 1 |
13 other studies available for chlordiazepoxide and Aging
| Article | Year |
|---|---|
[Pharmacokinetic of benzodiazepines in old age].
Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Half-Life; Humans; Lorazepam; M | 1981 |
Chronic chlordiazepoxide treatment on adult and newborn rats: effect on the GABA-benzodiazepine receptor complex.
Topics: Aging; Animals; Animals, Newborn; Chlordiazepoxide; Female; Flunitrazepam; gamma-Aminobutyric Acid; | 1983 |
Behavioral vigilance in rats: task validation and effects of age, amphetamine, and benzodiazepine receptor ligands.
Topics: Aging; Amphetamine; Animals; Arousal; Attention; Behavior, Animal; Carbolines; Chlordiazepoxide; Con | 1995 |
Effects of chlordiazepoxide and scopolamine, but not aging, on the detection and identification of conditional visual stimuli.
Topics: Aging; Animals; Arousal; Attention; Chlordiazepoxide; Conditioning, Operant; Dose-Response Relations | 1995 |
Effects of benzodiazepine receptor inverse agonists and nicotine on behavioral vigilance in senescent rats.
Topics: Aging; Animals; Attention; Behavior, Animal; Carbolines; Chlordiazepoxide; Discrimination, Psycholog | 1996 |
Disposition and elimination of minor tranquilizers in the aged and in patients with liver disease.
Topics: Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Hepatitis; Humans; Liver Cirrhosis; Li | 1978 |
Effects of liver disease and of aging on the disposition and elimination of sedatives.
Topics: Aging; Anti-Anxiety Agents; Chlordiazepoxide; Chlorpromazine; Diazepam; Half-Life; Hepatitis, Viral, | 1978 |
The effects of liver disease and aging on the disposition of diazepam, chlordiazepoxide, oxazepam and lorazepam in man.
Topics: Administration, Oral; Adult; Aged; Aging; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Female; H | 1978 |
Age-dependent modulation of in vivo cortical acetylcholine release by benzodiazepine receptor ligands.
Topics: Acetylcholine; Aging; Animals; Carbolines; Cerebral Cortex; Chlordiazepoxide; Darkness; Dialysis; GA | 1992 |
Age and gender effects on chlordiazepoxide kinetics: relation to antipyrine disposition.
Topics: Adult; Aging; Antipyrine; Body Weight; Chlordiazepoxide; Female; Half-Life; Humans; Injections, Intr | 1989 |
A comparison of diazepam stimuli in aged and adult rats.
Topics: Aging; Animals; Chlordiazepoxide; Diazepam; Discrimination Learning; Dose-Response Relationship, Dru | 1987 |
Plasma tryptophan and 5-HT metabolism in the CNS of the newborn rat.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Biological Transport; Blood-Brain Barrier; Brain; Bra | 1974 |
Hyperkinetic disease of children: diagnosis and therapy.
Topics: Adolescent; Adult; Aging; Brain Damage, Chronic; Child; Chlordiazepoxide; Dextroamphetamine; Humans; | 1966 |