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chlordiazepoxide and Acute Liver Injury, Drug-Induced

chlordiazepoxide has been researched along with Acute Liver Injury, Drug-Induced in 17 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Research Excerpts

ExcerptRelevanceReference
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."7.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)
"A combined cholestatic-hepatocellular injury and noncaseating granulomas occurred in two patients 1 and 4 weeks after phenylbutazone therapy."3.65Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases. ( Dhar, JK; Ishak, KG; Kirchner, JP, 1977)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199012 (70.59)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Morgan, RE2
Trauner, M1
van Staden, CJ2
Lee, PH1
Ramachandran, B1
Eschenberg, M1
Afshari, CA2
Qualls, CW1
Lightfoot-Dunn, R1
Hamadeh, HK2
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
KIDD, HB1
CUTHILL, JM1
GRIFFITHS, AB1
POWELL, DE1
COOK, GC1
SHERLOCK, S1
STROTHERS, G1
WOROBEC, T1
Krysicka-Doczkal, H1
Coleman, JH1
Evans, WE1
Ishak, KG1
Kirchner, JP1
Dhar, JK1
Horváth, T1
Gógl, A1
Ruzsa, C1
Ludány, A1
Jávor, T1
Berthelot, P1
Kehoe, MJ1
Kratzsch, KH1
Büttner, W1
Reinhardt, G1

Reviews

3 reviews available for chlordiazepoxide and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
Mechanisms and prediction of drug-induced liver disease.
    Gut, 1973, Volume: 14, Issue:4

    Topics: Adenosine Triphosphate; Age Factors; Animals; Bilirubin; Biotransformation; Carbon Isotopes; Carbon

1973
II. Major tranquilizers.
    Southern medical journal, 1971, Volume: 64, Issue:4

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Chlorpromazine; Fluphenazine; Hem

1971

Other Studies

14 other studies available for chlordiazepoxide and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
ANTIDEPRESSANT DRUGS AND LIVER DAMAGE.
    British medical journal, 1964, Mar-28, Volume: 1, Issue:5386

    Topics: Antidepressive Agents; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Chlorpromazine; Hep

1964
DEATH ASSOCIATED WITH TRANYLCYPROMINE AND CHEESE.
    Lancet (London, England), 1964, May-16, Volume: 1, Issue:7342

    Topics: Barbiturates; Cheese; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Diagnosis, Different

1964
JAUNDICE AND ITS RELATION TO THERAPEUTIC AGENTS.
    Lancet (London, England), 1965, Jan-23, Volume: 1, Issue:7378

    Topics: Alkaline Phosphatase; Antidepressive Agents; Aspartate Aminotransferases; Bilirubin; Chemical and Dr

1965
JAUNDICE AND ITS RELATION TO THERAPEUTIC AGENTS.
    Lancet (London, England), 1965, Feb-20, Volume: 1, Issue:7382

    Topics: Aluminum; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Hepatitis; Hydroxides; Imipramin

1965
BLOOD DYSCRASIAS ASSOCIATED WITH ANTITUBERCULOSIS AND/OR TRANQUILIZING CHEMOTHERAPY. A LONG-TERM CLINICAL OBSERVATION.
    Diseases of the chest, 1965, Volume: 47

    Topics: Aminosalicylic Acid; Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver In

1965
[Influence of liver damage on the anticonvulsant effect of chlordiazepoxide (Librium)].
    Acta physiologica Polonica, 1967, Volume: 18, Issue:5

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; F

1967
Pharmacotherapy of the acute alcohol withdrawal syndrome.
    Diseases of the nervous system, 1975, Volume: 36, Issue:4

    Topics: Alcoholism; Anti-Anxiety Agents; Barbiturates; Chemical and Drug Induced Liver Injury; Chloral Hydra

1975
Granulomas and cholestatic--hepatocellular injury associated with phenylbutazone. Report of two cases.
    The American journal of digestive diseases, 1977, Volume: 22, Issue:7

    Topics: Aged; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Cholestasis; Diazepam; Granuloma; Hu

1977
Drug-induced manifestation of hereditary hepatopathy.
    Acta medica Academiae Scientiarum Hungaricae, 1974, Volume: 31, Issue:3-4

    Topics: Adult; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Contraceptives, Oral, Combined; Dru

1974
[Intrahepatic cholestasis following chlordiazepoxide--contribution to the differential diagnosis of drug jaundice].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1972, May-01, Volume: 27, Issue:9

    Topics: Adult; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Cholestasis; Female; Humans; Male;

1972