Page last updated: 2024-10-24

chlordiazepoxide and Ache

chlordiazepoxide has been researched along with Ache in 27 studies

Chlordiazepoxide: An anxiolytic benzodiazepine derivative with anticonvulsant, sedative, and amnesic properties. It has also been used in the symptomatic treatment of alcohol withdrawal.
chlordiazepoxide : A benzodiazepine that is 3H-1,4-benzodiazepine 4-oxide substituted by a chloro group at position 7, a phenyl group at position 5 and a methylamino group at position 2.

Research Excerpts

ExcerptRelevanceReference
"The analgesic effects of single oral doses of viminol (70 mg), of viminol (70 mg) combined with chlordiazepoxide (10 mg) and of chlordiazepoxide (10 mg) were compared in 41 outpatients with chronic pain mostly due to neoplasms."5.04Viminol analgesic activity in elderly patients with chronic pain: a controlled evaluation, using self-rating questionnaires. ( Cavalli, G; Lodola, E; Moroni, M, 1978)
"1,4-Benzodiazepines are used in the treatment of anxiety disorders but have limited long-term use due to adverse effects."1.43Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABA ( Arnold, LA; Cerne, R; Cook, JM; Cramer, JW; Ernst, M; Jambrina, E; Jones, TM; Krambis, MJ; Li, G; Methuku, KR; Poe, MM; Rehman, S; Schkeryantz, JM; Stafford, DC; Teske, KA; Verma, AR; Witkin, JM, 2016)
"This is a report of the results of 25 experiments in five rats investigating the dose-response relationship for the antinociceptive effects of chlordiazepoxide given intrathecally in the dose range 0."1.28Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect. ( Boulter, N; Gent, JP; Goodchild, CS; Serrao, JM, 1991)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199022 (81.48)18.7374
1990's2 (7.41)18.2507
2000's1 (3.70)29.6817
2010's1 (3.70)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Poe, MM1
Methuku, KR1
Li, G1
Verma, AR1
Teske, KA1
Stafford, DC1
Arnold, LA1
Cramer, JW1
Jones, TM1
Cerne, R1
Krambis, MJ1
Witkin, JM1
Jambrina, E1
Rehman, S1
Ernst, M1
Cook, JM1
Schkeryantz, JM1
Craft, RM2
KLEIBEL, F2
FROMMEL, E1
FLEURY, C1
LEDEBUR, IV1
BEGUIN, M1
FAMILY, S1
Grossman, HC1
Hale, G1
Light, K1
Kolata, S1
Townsend, DA1
Goldfarb, Y1
Kusnecov, A1
Matzel, LD1
Bodnar, RJ1
Nicotera, N1
Kinscheck, IB1
Watkins, LR1
Mayer, DJ2
Schaefer, MC1
Thiébot, MH1
Jobert, A1
Soubrié, P1
Moroni, M1
Cavalli, G1
Lodola, E1
Moore, DS1
Nally, FF1
Almeida, SS1
Soares, EG1
Bichuette, MZ1
Graeff, FG1
de Oliveira, LM1
Boulter, N1
Serrao, JM1
Gent, JP1
Goodchild, CS1
Frenk, H1
Bossut, D1
Yosselson-Superstine, S1
Lipman, AG1
Sanders, SH1
Kubota, K1
Sugaya, K1
Matsuda, I1
Matsuoka, Y1
Terawaki, Y1
Walsh, TJ1
McLamb, RL1
Tilson, HA1
Warren, DA1
Rosellini, RA1
Britton, KT1
Morgan, J1
Rivier, J1
Vale, W1
Koob, GF1
Avis, HH1
Hertrich, O1
Zakusov, VV1
Singh, G1
Verma, HC1
Jaques, R1
Helfer, H1
Pagliarini, G1
Pollazzon, G1
Ridolfi, C1
Rizzi, R2
Vacondio, L1
Cecconello, D1
Bissanti, A1

Reviews

1 review available for chlordiazepoxide and Ache

ArticleYear
The neuropharmacology of aggression: a critical review.
    Psychological bulletin, 1974, Volume: 81, Issue:1

    Topics: Acetylcholine; Aggression; Animals; Appetitive Behavior; Behavior, Animal; Brain Chemistry; Catechol

1974

Trials

3 trials available for chlordiazepoxide and Ache

ArticleYear
Viminol analgesic activity in elderly patients with chronic pain: a controlled evaluation, using self-rating questionnaires.
    International journal of clinical pharmacology and biopharmacy, 1978, Volume: 16, Issue:11

    Topics: Aged; Chlordiazepoxide; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy

1978
Adjunctive antianxiety agents in the management of chronic pain.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:2

    Topics: Adult; Aged; Analgesics; Anti-Anxiety Agents; Arthritis; Chlordiazepoxide; Chronic Disease; Double-B

1985
[Clinico-statistical pluricentral study of postoperative pain].
    Minerva anestesiologica, 1968, Volume: 34, Issue:5

    Topics: Aminopyrine; Analgesics; Barbiturates; Chlordiazepoxide; Female; Humans; Imidazoles; Italy; Ketones;

1968

Other Studies

23 other studies available for chlordiazepoxide and Ache

ArticleYear
Synthesis and Characterization of a Novel γ-Aminobutyric Acid Type A (GABA
    Journal of medicinal chemistry, 2016, 12-08, Volume: 59, Issue:23

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Dose-Response Relationship, Drug; Epilepsy;

2016
Burrowing as an index of inflammatory pain in male vs. female rats.
    Behavioural pharmacology, 2023, 02-01, Volume: 34, Issue:1

    Topics: Analgesics; Animals; Chlordiazepoxide; Female; Hyperalgesia; Inflammation; Male; Pain; Rats; Rats, S

2023
Burrowing as an index of inflammatory pain in male vs. female rats.
    Behavioural pharmacology, 2023, 02-01, Volume: 34, Issue:1

    Topics: Analgesics; Animals; Chlordiazepoxide; Female; Hyperalgesia; Inflammation; Male; Pain; Rats; Rats, S

2023
Burrowing as an index of inflammatory pain in male vs. female rats.
    Behavioural pharmacology, 2023, 02-01, Volume: 34, Issue:1

    Topics: Analgesics; Animals; Chlordiazepoxide; Female; Hyperalgesia; Inflammation; Male; Pain; Rats; Rats, S

2023
Burrowing as an index of inflammatory pain in male vs. female rats.
    Behavioural pharmacology, 2023, 02-01, Volume: 34, Issue:1

    Topics: Analgesics; Animals; Chlordiazepoxide; Female; Hyperalgesia; Inflammation; Male; Pain; Rats; Rats, S

2023
[ON THE THERAPY OF CANCER PAIN].
    Munchener medizinische Wochenschrift (1950), 1964, Feb-21, Volume: 106

    Topics: Antidepressive Agents; Chlordiazepoxide; Humans; Neoplasms; Opipramol; Pain; Promazine; Thiazines; T

1964
[CONTROL OF THE COMPLEX OF AUTONOMIC COMPLAINTS IN CANCER PATIENTS].
    Die Medizinische Welt, 1964, Mar-14, Volume: 11

    Topics: Chlordiazepoxide; Humans; Morphine Dependence; Neoplasms; Pain; Sleep Initiation and Maintenance Dis

1964
THE PLACE OF ACETYLSALICYLIC ACID IN PSYCHOPHARMACOLOGY. AN EXPERIMENTAL STUDY.
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Amphetamine; Amphetamines; Animals; Aspirin; Body Temperature Regulation; Chlordiazepoxide; Chlorpro

1963
Pharmacological modulation of stress reactivity dissociates general learning ability from the propensity for exploration.
    Behavioral neuroscience, 2007, Volume: 121, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Chlordiazepoxide; Corticosterone; Discrim

2007
Neuroleptic and analgesic interactions upon pain and activity measures.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:3

    Topics: Analgesics; Animals; Antipsychotic Agents; Chlordiazepoxide; Chlorpromazine; Deoxyglucose; Drug Inte

1982
Fear is not critical to classically conditioned analgesia: the effects of periaqueductal gray lesions and administration of chlordiazepoxide.
    Brain research, 1984, Apr-23, Volume: 298, Issue:1

    Topics: Animals; Brain Mapping; Chlordiazepoxide; Conditioning, Classical; Electroshock; Fear; Male; Pain; P

1984
A regimen of tricyclic compounds and carbamazepine for treating trigeminal neuralgia pain.
    Quintessence international, dental digest, 1981, Volume: 12, Issue:11

    Topics: Amitriptyline; Carbamazepine; Chlordiazepoxide; Drug Combinations; Humans; Pain; Trigeminal Neuralgi

1981
Chlordiazepoxide and GABA injected into raphé dorsalis release the conditioned behavioural suppression induced in rats by a conflict procedure without nociceptive component.
    Neuropharmacology, 1980, Volume: 19, Issue:7

    Topics: Animals; Chlordiazepoxide; Conditioning, Operant; Conflict, Psychological; Diazepam; gamma-Aminobuty

1980
Atypical facial pain: an analysis of 100 patients with discussion.
    Dental journal, 1975, Volume: 41, Issue:7

    Topics: Adult; Age Factors; Amitriptyline; Anxiety Disorders; Chlordiazepoxide; Depression; Diagnosis, Diffe

1975
Effects of early postnatal malnutrition and chlordiazepoxide on experimental aversive situations.
    Physiology & behavior, 1992, Volume: 51, Issue:6

    Topics: Animals; Anxiety; Avoidance Learning; Body Weight; Chlordiazepoxide; Eating; Electroshock; Male; Mot

1992
Spinally mediated antinociception following intrathecal chlordiazepoxide--further evidence for a benzodiazepine spinal analgesic effect.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:5

    Topics: Analgesia, Epidural; Animals; Catheters, Indwelling; Chlordiazepoxide; Dose-Response Relationship, D

1991
Is substance P a primary afferent neurotransmitter for nociceptive input? III. Valproic acid and chlordiazepoxide decrease behaviors elicited by intrathecal injection of substance P and excitatory compounds.
    Brain research, 1988, Jul-12, Volume: 455, Issue:2

    Topics: Animals; Anticonvulsants; Chlordiazepoxide; Injections, Spinal; Kainic Acid; Male; Morphine; Nocicep

1988
Reversal of antinociceptive effect of cholecystokinin by benzodiazepines and a benzodiazepine antagonist, Ro 15-1788.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:1

    Topics: Analgesics; Animals; Anti-Anxiety Agents; Benzodiazepinones; Chlordiazepoxide; Cholecystokinin; Diaz

1985
A comparison of the effects of RO15,1788 and chlordiazepoxide on hot-plate latencies, acoustic startle, and locomotor activity.
    Psychopharmacology, 1986, Volume: 88, Issue:4

    Topics: Acoustic Stimulation; Animals; Benzodiazepinones; Chlordiazepoxide; Flumazenil; Male; Motor Activity

1986
Effects of Librium and shock controllability upon nociception and contextual fear.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1

    Topics: Animals; Avoidance Learning; Chlordiazepoxide; Conditioning, Operant; Electroshock; Fear; Helplessne

1988
Chlordiazepoxide attenuates response suppression induced by corticotropin-releasing factor in the conflict test.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: Analgesics; Animals; Anxiety; Chlordiazepoxide; Conflict, Psychological; Corticotropin-Releasing Hor

1985
[Neuroleptics, thymoleptics and tranquilizers in neurological therapy].
    Bibliotheca psychiatrica et neurologica, 1969, Volume: 139

    Topics: Basal Ganglia Diseases; Chlordiazepoxide; Chlorpromazine; Diazepam; Epilepsy; Extrapyramidal Tracts;

1969
[The effect tranquilizers and antidepressants on the summation of impulses of different modalities].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 75, Issue:4

    Topics: Animals; Auditory Perception; Central Nervous System; Chlordiazepoxide; Conditioning, Classical; Dep

1973
Drug treatment of chronic intractable pain in patients referred to a psychiatry clinic.
    Journal of the Indian Medical Association, 1971, Jun-01, Volume: 56, Issue:11

    Topics: Adolescent; Adult; Aged; Amitriptyline; Anxiety; Chlordiazepoxide; Chronic Disease; Depression; Fema

1971
The antinociceptive action of a novel anxiolytic and tensiolytic drug (benzoctamine) in two different writhing syndromes.
    Pharmacology, 1971, Volume: 6, Issue:1

    Topics: Analgesics; Animals; Anthracenes; Arachidonic Acids; Chlordiazepoxide; Chlorpromazine; Imipramine; M

1971
[Postoperative vomiting and pain].
    Acta anaesthesiologica, 1968, Volume: 19

    Topics: Chlordiazepoxide; Female; Humans; Hypnotics and Sedatives; Male; Pain; Perphenazine; Postoperative C

1968