chlordecone has been researched along with Libman-Sacks Disease in 3 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In murine models of systemic lupus erythematosus (SLE), administration of either prolactin or estradiol (E2) increases autoimmunity, and there is evidence that elevated prolactin in response to E2 administration may contribute substantially to E2 effects." | 1.34 | Diminished prolactin from chlordecone treatment in ovariectomized (NZBxNZW)F(1) mice. ( Butfiloski, EJ; Roberts, SM; Sobel, ES; Wang, F, 2007) |
| "Chlordecone treatment in (NZBxNZW) F(1) mice shortened significantly the time to onset of elevated autoantibody titers and renal disease in a dose-related manner." | 1.33 | Comparison of chlordecone effects on autoimmunity in (NZBxNZW) F(1) and BALB/c mice. ( Butfiloski, E; Croker, B; Roberts, SM; Sobel, ES; Wang, F, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sobel, ES | 3 |
| Wang, F | 3 |
| Butfiloski, E | 1 |
| Croker, B | 1 |
| Roberts, SM | 3 |
| Butfiloski, EJ | 2 |
| Morel, L | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Organochlorine Pesticide Exposure in Residents Near Lake Apopka[NCT02530814] | 20 participants (Actual) | Observational | 2015-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for chlordecone and Libman-Sacks Disease
| Article | Year |
|---|---|
Comparison of chlordecone effects on autoimmunity in (NZBxNZW) F(1) and BALB/c mice.
Topics: Animals; Antibodies, Antinuclear; Autoimmunity; Chlordecone; Chromatin; Delayed-Action Preparations; | 2006 |
Acceleration of autoimmunity by organochlorine pesticides: a comparison of splenic B-cell effects of chlordecone and estradiol in (NZBxNZW)F1 mice.
Topics: Animals; Antigens, Differentiation; Apoptosis; Autoimmunity; B-Lymphocytes; Cell Proliferation; Chlo | 2007 |
Diminished prolactin from chlordecone treatment in ovariectomized (NZBxNZW)F(1) mice.
Topics: Animals; Autoimmunity; Chlordecone; Dose-Response Relationship, Drug; Estradiol; Female; Insecticide | 2007 |