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chlordecone and Disease Models, Animal

chlordecone has been researched along with Disease Models, Animal in 4 studies

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Chlordecone does not cause liver injuries or any inflammation by itself at low doses, but it can potentiate the hepatotoxic effects of other chemicals and drugs."1.48Chlordecone potentiates auto-immune hepatitis and promotes brain entry of MHV3 during viral hepatitis in mouse models. ( Gelu-Simeon, M; Genet, V; Lamontagne, L; Piquet-Pellorce, C; Samson, M; Tabet, E, 2018)
"Treatment with chlordecone, methoxychlor, or o,p -dichlorodiphenyltrichloroethane (o,p -DDT) significantly decreased the time to onset of renal impairment, as did treatment with 17ss-estradiol used as a positive control."1.33Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice. ( Butfiloski, EJ; Croker, BP; Gianini, J; Roberts, SM; Schiffenbauer, J; Sobel, ES, 2005)
"Chlordecone treatment in (NZBxNZW) F(1) mice shortened significantly the time to onset of elevated autoantibody titers and renal disease in a dose-related manner."1.33Comparison of chlordecone effects on autoimmunity in (NZBxNZW) F(1) and BALB/c mice. ( Butfiloski, E; Croker, B; Roberts, SM; Sobel, ES; Wang, F, 2006)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tabet, E1
Gelu-Simeon, M1
Genet, V1
Lamontagne, L1
Piquet-Pellorce, C1
Samson, M1
Sobel, ES3
Gianini, J1
Butfiloski, EJ2
Croker, BP1
Schiffenbauer, J1
Roberts, SM3
Wang, F2
Butfiloski, E1
Croker, B1
Morel, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Organochlorine Pesticide Exposure in Residents Near Lake Apopka[NCT02530814]20 participants (Actual)Observational2015-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for chlordecone and Disease Models, Animal

ArticleYear
Chlordecone potentiates auto-immune hepatitis and promotes brain entry of MHV3 during viral hepatitis in mouse models.
    Toxicology letters, 2018, Dec-15, Volume: 299

    Topics: Acute Disease; Animals; Brain; Chlordecone; Concanavalin A; Disease Models, Animal; Disease Progress

2018
Acceleration of autoimmunity by organochlorine pesticides in (NZB x NZW)F1 mice.
    Environmental health perspectives, 2005, Volume: 113, Issue:3

    Topics: Animals; Autoimmunity; Chlordecone; DDT; Disease Models, Animal; Estrogens, Non-Steroidal; Female; I

2005
Comparison of chlordecone effects on autoimmunity in (NZBxNZW) F(1) and BALB/c mice.
    Toxicology, 2006, Feb-01, Volume: 218, Issue:2-3

    Topics: Animals; Antibodies, Antinuclear; Autoimmunity; Chlordecone; Chromatin; Delayed-Action Preparations;

2006
Acceleration of autoimmunity by organochlorine pesticides: a comparison of splenic B-cell effects of chlordecone and estradiol in (NZBxNZW)F1 mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2007, Volume: 99, Issue:1

    Topics: Animals; Antigens, Differentiation; Apoptosis; Autoimmunity; B-Lymphocytes; Cell Proliferation; Chlo

2007