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chlordecone and Carbon Tetrachloride Poisoning

chlordecone has been researched along with Carbon Tetrachloride Poisoning in 10 studies

Carbon Tetrachloride Poisoning: Poisoning that results from ingestion, injection, inhalation, or skin absorption of CARBON TETRACHLORIDE.

Research Excerpts

ExcerptRelevanceReference
"Hepatic failure was evaluated by measuring plasma glucose, ammonia, bilirubin, aspartate transaminase (AST), alanine transaminase (ALT), sorbitol dehydrogenase (SDH), hepatic ATP, glycogen, and by histological and histomorphometric analyses."5.29Hepatic failure leads to lethality of chlordecone-amplified hepatotoxicity of carbon tetrachloride. ( Mehendale, HM; Soni, MG, 1993)
"Hepatic failure was evaluated by measuring plasma glucose, ammonia, bilirubin, aspartate transaminase (AST), alanine transaminase (ALT), sorbitol dehydrogenase (SDH), hepatic ATP, glycogen, and by histological and histomorphometric analyses."1.29Hepatic failure leads to lethality of chlordecone-amplified hepatotoxicity of carbon tetrachloride. ( Mehendale, HM; Soni, MG, 1993)
" For comparison, a large toxic dose of CCl4 was also employed."1.28Hepatic polyamines and related enzymes following chlordecone-potentiated carbon tetrachloride toxicity in rats. ( Mehendale, HM; Rao, SB; Young, RA, 1989)
" Ca2+ in whole liver, mitochondria, microsomes or in cytosolic fraction was unaltered in any group of animals receiving chlordecone + oil treatments, indicating that chlordecone alone does not alter whole liver content or hepatic subcellular distribution of Ca2+, even after exposure to toxic levels (50 or 100 ppm)."1.27Excessive hepatic accumulation of intracellular Ca2+ in chlordecone potentiated CCl4 toxicity. ( Agarwal, AK; Mehendale, HM, 1984)
"Chlordecone (CD) pretreatment is known to markedly potentiate CCl4 hepatotoxicity."1.27Protection of chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy. ( Bell, AN; Lockard, VG; Mehendale, HM; Young, RA, 1988)
"Chlordecone treatment produced approximately a 17-fold potentiation of the CCl4-dependent loss of cytochrome P-450 and glucose-6-phosphatase activity, so that a dose of 6 microliters CCl4 per 100 g body weight in the chlordecone-treated animals resulted in a similar amount of damage as observed with 100 microliters CCl4 per 100 g body weight in controls."1.27Potentiation of carbon tetrachloride hepatotoxicity by chlordecone: dose-response relationships and increased covalent binding in vivo. ( Britton, RS; Dolak, JA; Glende, EA; Recknagel, RO, 1987)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19908 (80.00)18.7374
1990's2 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Agarwal, AK1
Mehendale, HM7
Ebel, RE1
McGrath, EA1
Dalu, A1
Warbritton, A1
Bucci, TJ1
Soni, MG1
Bell, AN2
Young, RA3
Lockard, VG2
Britton, RS1
Dolak, JA1
Glende, EA2
Recknagel, RO1
Rao, SB1
Kodavanti, PR2
Joshi, UM2
Lee, PY1

Other Studies

10 other studies available for chlordecone and Carbon Tetrachloride Poisoning

ArticleYear
Excessive hepatic accumulation of intracellular Ca2+ in chlordecone potentiated CCl4 toxicity.
    Toxicology, 1984, Feb-14, Volume: 30, Issue:1

    Topics: Animals; Calcium; Carbon Tetrachloride Poisoning; Chlordecone; Cytosol; Drug Synergism; Insecticides

1984
CCl4-hepatotoxicity in the Mongolian gerbil: influence of monooxygenase system induction.
    Toxicology letters, 1984, Volume: 22, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chlordec

1984
Age-related susceptibility to chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality is due to hepatic quiescence.
    Pediatric research, 1995, Volume: 38, Issue:2

    Topics: Animals; Carbon Tetrachloride Poisoning; Cell Cycle; Cell Division; Chemical and Drug Induced Liver

1995
Hepatic failure leads to lethality of chlordecone-amplified hepatotoxicity of carbon tetrachloride.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1993, Volume: 21, Issue:4

    Topics: Animals; Carbon Tetrachloride Poisoning; Chlordecone; Clinical Enzyme Tests; Kidney; Liver Failure;

1993
Protection of chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy.
    Archives of toxicology, 1988, Volume: 61, Issue:5

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlordecone; Cobalt

1988
Potentiation of carbon tetrachloride hepatotoxicity by chlordecone: dose-response relationships and increased covalent binding in vivo.
    Journal of biochemical toxicology, 1987,Spring, Volume: 2

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlordecone; Cytoch

1987
Hepatic polyamines and related enzymes following chlordecone-potentiated carbon tetrachloride toxicity in rats.
    Journal of biochemical toxicology, 1989,Spring, Volume: 4, Issue:1

    Topics: Adenosylmethionine Decarboxylase; Alanine Transaminase; Amine Oxidase (Copper-Containing); Animals;

1989
Role of hepatocellular regeneration in chlordecone potentiated hepatotoxicity of carbon tetrachloride.
    Archives of toxicology, 1989, Volume: 63, Issue:5

    Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Cell Nucleus; Chemical and Drug Induced Li

1989
Chlordecone (Kepone)-potentiated carbon tetrachloride hepatotoxicity in partially hepatectomized rats--a histomorphometric study.
    Journal of applied toxicology : JAT, 1989, Volume: 9, Issue:6

    Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ch

1989
Isopropanol and chlordecone potentiation of carbon tetrachloride liver injury: retention of potentiating action in hepatocyte suspensions prepared from rats given isopropanol or chlordecone.
    Experimental and molecular pathology, 1985, Volume: 42, Issue:2

    Topics: 1-Propanol; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cells, Cultured; C

1985