chlordecone has been researched along with Acute Liver Injury, Drug-Induced in 32 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is often assumed that at a younger age populations are at higher risk of toxic effects from exposure to toxic chemicals." | 2.39 | Efficient tissue repair underlies the resiliency of postnatally developing rats to chlordecone + CCl4 hepatotoxicity. ( Dalu, A; Mehendale, HM, 1996) |
| " It appears that a greater bioactivation of CCl4 in chlordecone treated animals resulted in an initial potentiation of toxic events in the liver cells." | 2.37 | Potentiation of halomethane hepatotoxicity: chlordecone and carbon tetrachloride. ( Mehendale, HM, 1984) |
| "Chlordecone (CD) pretreatment is known to markedly potentiate CCl4 hepatotoxicity." | 1.27 | Protection of chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy. ( Bell, AN; Lockard, VG; Mehendale, HM; Young, RA, 1988) |
| "Chlordecone treatment produced approximately a 17-fold potentiation of the CCl4-dependent loss of cytochrome P-450 and glucose-6-phosphatase activity, so that a dose of 6 microliters CCl4 per 100 g body weight in the chlordecone-treated animals resulted in a similar amount of damage as observed with 100 microliters CCl4 per 100 g body weight in controls." | 1.27 | Potentiation of carbon tetrachloride hepatotoxicity by chlordecone: dose-response relationships and increased covalent binding in vivo. ( Britton, RS; Dolak, JA; Glende, EA; Recknagel, RO, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (68.75) | 18.7374 |
| 1990's | 9 (28.13) | 18.2507 |
| 2000's | 1 (3.13) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murali, B | 1 |
| Korrapati, MC | 1 |
| Warbritton, A | 2 |
| Latendresse, JR | 1 |
| Mehendale, HM | 21 |
| Guzelian, PS | 1 |
| Vranian, G | 1 |
| Boylan, JJ | 1 |
| Cohn, WJ | 1 |
| Blanke, RV | 1 |
| Davis, ME | 1 |
| Cianflone, DJ | 1 |
| Hewitt, WR | 1 |
| Villeneuve, DC | 2 |
| Plaa, GL | 2 |
| Chu, I | 1 |
| Becking, GC | 1 |
| Iverson, F | 1 |
| Ritter, L | 1 |
| Valli, VE | 1 |
| Reynolds, LM | 1 |
| Klingensmith, JS | 1 |
| Lockard, VG | 5 |
| O'Neal, RM | 2 |
| Dalu, A | 3 |
| Bucci, TJ | 1 |
| Rochelle, LG | 1 |
| Curtis, LR | 2 |
| Rao, PS | 1 |
| Blain, RB | 1 |
| Reeves, R | 1 |
| Ewald, KA | 1 |
| Leonard, D | 1 |
| Calabrese, EJ | 1 |
| Larson, PS | 1 |
| Egle, JL | 1 |
| Hennigar, GR | 1 |
| Lane, RW | 1 |
| Borzelleca, JF | 1 |
| Williams, WL | 1 |
| Kodavanti, PR | 4 |
| Kodavanti, UP | 2 |
| Faroon, OM | 1 |
| Rao, SB | 2 |
| Young, RA | 3 |
| Ikegwuonu, FI | 1 |
| Swartz, WJ | 1 |
| Schutzmann, RL | 1 |
| Caillé, G | 1 |
| Vézina, M | 1 |
| Iijima, M | 1 |
| Côté, MG | 1 |
| Fouse, BL | 1 |
| Hodgson, E | 1 |
| Bell, AN | 2 |
| Britton, RS | 1 |
| Dolak, JA | 1 |
| Glende, EA | 2 |
| Recknagel, RO | 1 |
| Purushotham, KR | 1 |
| Joshi, UM | 2 |
| Lee, PY | 1 |
3 reviews available for chlordecone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Potentiation of halomethane hepatotoxicity: chlordecone and carbon tetrachloride.
Topics: Animals; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Cytochr | 1984 |
Efficient tissue repair underlies the resiliency of postnatally developing rats to chlordecone + CCl4 hepatotoxicity.
Topics: Animals; Animals, Newborn; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone | 1996 |
Mechanism of the lethal interaction of chlordecone and CCl4 at non-toxic doses.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Synergism; | 1989 |
29 other studies available for chlordecone and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Tolerance of aged Fischer 344 rats against chlordecone-amplified carbon tetrachloride toxicity.
Topics: Aging; Animals; Blotting, Western; Carbon Tetrachloride; Cell Nucleus; Chemical and Drug Induced Liv | 2004 |
Liver structure and function in patients poisoned with chlordecone (Kepone).
Topics: Adolescent; Adult; Antipyrine; Biopsy; Chemical and Drug Induced Liver Injury; Chlordecone; gamma-Gl | 1980 |
Functional and biochemical correlates of chlordecone exposure and its enhancement of CCl4 hepatotoxicity.
Topics: Animals; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Inter | 1980 |
Role of biotransformation in the alterations of chloroform hepatotoxicity produced by Kepone and mirex.
Topics: Animals; Biotransformation; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; Drug In | 1980 |
Short-term study of the combined effects of mirex, photomirex, and kepone with halogenated biphenyls in rats.
Topics: Animals; Biphenyl Compounds; Chemical and Drug Induced Liver Injury; Chlordecone; Diet; Fatty Liver; | 1980 |
Onset and recovery from chlordecone- and mirex-induced hepatobiliary dysfunction.
Topics: Animals; Bile; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chlordecone; Eating; | 1981 |
Potentiation of CCl4 lethality by chlordecone.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Synergism; | 1982 |
Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: a light and electron microscopic study.
Topics: Animals; Carbon Tetrachloride; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlordecone; Cy | 1983 |
Chlordecone-induced potentiation of carbon tetrachloride hepatotoxicity: a morphometric and biochemical study.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Cell Nucleus; Chem | 1983 |
Age-related susceptibility to chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality is due to hepatic quiescence.
Topics: Animals; Carbon Tetrachloride Poisoning; Cell Cycle; Cell Division; Chemical and Drug Induced Liver | 1995 |
Distribution of chlordecone to liver plasma membranes and recovery from hepatobiliary dysfunction in rats.
Topics: Animals; Bile; Biliary Tract Diseases; Carbon Radioisotopes; Cell Membrane; Cell Membrane Permeabili | 1994 |
Colchicine antimitosis abolishes resiliency of postnatally developing rats to chlordecone-amplified carbon tetrachloride hepatotoxicity and lethality.
Topics: Animals; Carbon Tetrachloride; Cell Division; Chemical and Drug Induced Liver Injury; Chlordecone; C | 1998 |
Susceptibility to chlordecone-carbon tetrachloride induced hepatotoxicity and lethality is both age and sex dependent.
Topics: Age Factors; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemi | 1999 |
Acute, subchronic, and chronic toxicity of chlordecone.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlordecone; Dogs; Dose-Response Relat | 1979 |
Potentiation of the hepatotoxicity of carbon tetrachloride following preexposure to chlordecone (kepone) in the male rat.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Synergism; | 1979 |
Pivotal role of hepatocellular regeneration in the ultimate hepatotoxicity of CCl4 in chlordecone-, mirex-, or phenobarbital-pretreated rats.
Topics: Animals; Autoradiography; Carbon Tetrachloride; Cell Size; Chemical and Drug Induced Liver Injury; C | 1992 |
Perturbations in polyamines and related enzymes following chlordecone-potentiated bromotrichloromethane hepatotoxicity.
Topics: Acetyltransferases; Adenosylmethionine Decarboxylase; Alanine Transaminase; Amino Acids, Diamino; An | 1990 |
Carbon tetrachloride-induced alterations of hepatic calmodulin and free calcium levels in rats pretreated with chlordecone.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Calcium; Calmodulin; Carbon Tetrachlorid | 1991 |
Biochemical assessment of the genotoxicity of the in vitro interaction between chlordecone and carbon tetrachloride in rat hepatocytes.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; DNA Damage; Live | 1991 |
Reaction of the mouse liver to kepone exposure.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlordecone; Chromatography, Gas; Estr | 1986 |
Chloroform interaction with chlordecone and mirex: correlation between biochemical and histological indices of toxicity and quantitative tissue levels.
Topics: Adipose Tissue; Animals; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; Chromatogr | 1987 |
Effect of chlordecone and mirex on the acute hepatotoxicity of acetaminophen in mice.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Interactions; Inse | 1987 |
Protection of chlordecone-potentiated carbon tetrachloride hepatotoxicity and lethality by partial hepatectomy.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlordecone; Cobalt | 1988 |
Potentiation of carbon tetrachloride hepatotoxicity by chlordecone: dose-response relationships and increased covalent binding in vivo.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chlordecone; Cytoch | 1987 |
The time course of liver injury and [3H]thymidine incorporation in chlordecone-potentiated CHCl3 hepatotoxicity.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Nucleus; Chemical and Drug Induced | 1989 |
Role of hepatocellular regeneration in chlordecone potentiated hepatotoxicity of carbon tetrachloride.
Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Cell Nucleus; Chemical and Drug Induced Li | 1989 |
Protection from chlordecone (Kepone)-potentiated CCl4 hepatotoxicity in rats by fructose 1,6-diphosphate.
Topics: Acetyltransferases; Adenosine Triphosphate; Adenosylmethionine Decarboxylase; Alanine Transaminase; | 1989 |
Chlordecone (Kepone)-potentiated carbon tetrachloride hepatotoxicity in partially hepatectomized rats--a histomorphometric study.
Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Ch | 1989 |
Isopropanol and chlordecone potentiation of carbon tetrachloride liver injury: retention of potentiating action in hepatocyte suspensions prepared from rats given isopropanol or chlordecone.
Topics: 1-Propanol; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Cells, Cultured; C | 1985 |