chlordecone has been researched along with Action Tremor in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to correlate the chlordecone-elicited tremor activity with alterations of brain neurotransmitters." | 7.67 | Effects of chlordecone exposure on brain neurotransmitters: possible involvement of the serotonin system in chlordecone-elicited tremor. ( Gerhart, J; Hong, JS; Tilson, HA; Uphouse, LL; Wilson, WE, 1984) |
| " In contrast, the induction of tremor by chlordecone, a neurotoxic agent that affects neuronal ionic processes, is significantly attenuated by pretreatment with DFMO." | 7.67 | Inhibition of ornithine decarboxylase alters neurological responsiveness to a tremorigen. ( Bondy, SC; Emerich, D; Tilson, HA, 1986) |
| "Pretreatment of rats with phenoxybenzamine (5 mg/kg; SC), an alpha adrenergic antagonist, decreased the peak tremor power and startle magnitude of rats subsequently given DDT (75 mg/kg; PO) or chlordecone (60 mg/kg; IP), without having a significant effect on control animals." | 7.67 | Pharmacological modification of tremor and enhanced acoustic startle by chlordecone and p,p'-DDT. ( Gallus, JA; Herr, DW; Tilson, HA, 1987) |
| " A single injection of tremorigenic doses of chlordecone to adult male Fischer-344 rats resulted in significant increases in MHPG concentrations in hypothalamus, brain stem, cerebellum, and caudate nucleus." | 7.67 | Effect of chlordecone (Kepone) on the rat brain concentration of 3-methoxy-4-hydroxyphenylglycol: evidence for a possible involvement of the norepinephrine system in chlordecone-induced tremor. ( Chen, PH; Hong, JS; Karoum, F; Marbury, GD; Tilson, HA, 1985) |
| "Organochlorine insecticides such as DDT and chlordecone produce tremor in exposed individuals." | 7.67 | Studies on the mechanism of chlordecone-induced tremor in rats. ( Gerhart, JM; Hong, JS; Tilson, HA, 1985) |
| "A series of psychopharmacological agents were administered to adult male Fischer-344 rats pretreated with a tremorigenic dose of chlordecone in an attempt to elucidate the involvement of spinal and supraspinal processes in the mediation and/or expression of chlordecone-induced tremor." | 7.66 | Studies on the possible sites of chlordecone-induced tremor in rats. ( Gerhart, JM; Hong, JS; Tilson, HA, 1983) |
| " The onset of tremors was evident as early as 2 hr in 50 mg/kg dosed rats." | 5.26 | Acute chlordecone toxicity in rats: a relationship between tremor and ATPase activities. ( Desaiah, D; Grice, T; Jordan, JE; Mishra, SK, 1981) |
| "The purpose of this study was to correlate the chlordecone-elicited tremor activity with alterations of brain neurotransmitters." | 3.67 | Effects of chlordecone exposure on brain neurotransmitters: possible involvement of the serotonin system in chlordecone-elicited tremor. ( Gerhart, J; Hong, JS; Tilson, HA; Uphouse, LL; Wilson, WE, 1984) |
| " In contrast, the induction of tremor by chlordecone, a neurotoxic agent that affects neuronal ionic processes, is significantly attenuated by pretreatment with DFMO." | 3.67 | Inhibition of ornithine decarboxylase alters neurological responsiveness to a tremorigen. ( Bondy, SC; Emerich, D; Tilson, HA, 1986) |
| "Pretreatment of rats with phenoxybenzamine (5 mg/kg; SC), an alpha adrenergic antagonist, decreased the peak tremor power and startle magnitude of rats subsequently given DDT (75 mg/kg; PO) or chlordecone (60 mg/kg; IP), without having a significant effect on control animals." | 3.67 | Pharmacological modification of tremor and enhanced acoustic startle by chlordecone and p,p'-DDT. ( Gallus, JA; Herr, DW; Tilson, HA, 1987) |
| " A single injection of tremorigenic doses of chlordecone to adult male Fischer-344 rats resulted in significant increases in MHPG concentrations in hypothalamus, brain stem, cerebellum, and caudate nucleus." | 3.67 | Effect of chlordecone (Kepone) on the rat brain concentration of 3-methoxy-4-hydroxyphenylglycol: evidence for a possible involvement of the norepinephrine system in chlordecone-induced tremor. ( Chen, PH; Hong, JS; Karoum, F; Marbury, GD; Tilson, HA, 1985) |
| "Organochlorine insecticides such as DDT and chlordecone produce tremor in exposed individuals." | 3.67 | Studies on the mechanism of chlordecone-induced tremor in rats. ( Gerhart, JM; Hong, JS; Tilson, HA, 1985) |
| " When challenged with harmine, a known tremorogen with putative effects on olivocerebellar pathways, chlordecone-exposed males were less responsive than vehicle-exposed littermates in a spectral analysis of movement." | 3.67 | Evaluation of long-term consequences in behavioral and/or neural function following neonatal chlordecone exposure. ( Mactutus, CF; Tilson, HA, 1985) |
| "A series of psychopharmacological agents were administered to adult male Fischer-344 rats pretreated with a tremorigenic dose of chlordecone in an attempt to elucidate the involvement of spinal and supraspinal processes in the mediation and/or expression of chlordecone-induced tremor." | 3.66 | Studies on the possible sites of chlordecone-induced tremor in rats. ( Gerhart, JM; Hong, JS; Tilson, HA, 1983) |
| "Industrial overexposure to chlordecone, an organochlorine insecticide, caused tremor in 76 of 148 exposed workers." | 3.66 | Chlordecone intoxication in man. I. Clinical observations. ( Houff, SA; Martinez, AJ; Selhorst, JB; Taylor, JR, 1978) |
| "Chlordecone (Kepone) is a polychlorinated hydrocarbon that has a low affinity for the estrogen receptor." | 1.29 | Estradiol-chlordecone (Kepone) interactions: additive effect of combinations for uterotropic and embryo implantation functions. ( Johnson, DC, 1996) |
| "Pretreatment with phenytoin significantly attenuated the tremor produced by p,p'-DDT but enhanced that produced by chlordecone." | 1.27 | 5,5-Diphenylhydantoin antagonizes neurochemical and behavioral effects of p,p'-DDT but not of chlordecone. ( Hong, JS; Hudson, PM; Tilson, HA, 1986) |
| " The onset of tremors was evident as early as 2 hr in 50 mg/kg dosed rats." | 1.26 | Acute chlordecone toxicity in rats: a relationship between tremor and ATPase activities. ( Desaiah, D; Grice, T; Jordan, JE; Mishra, SK, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jordan, JE | 1 |
| Grice, T | 1 |
| Mishra, SK | 1 |
| Desaiah, D | 1 |
| Guzelian, PS | 1 |
| Gerhart, JM | 3 |
| Hong, JS | 6 |
| Uphouse, LL | 2 |
| Tilson, HA | 9 |
| Gerhart, J | 1 |
| Wilson, WE | 1 |
| Johnson, DC | 1 |
| Taylor, JR | 1 |
| Selhorst, JB | 1 |
| Houff, SA | 1 |
| Martinez, AJ | 1 |
| Cannon, SB | 1 |
| Kimbrough, RD | 1 |
| Larson, PS | 1 |
| Egle, JL | 1 |
| Hennigar, GR | 1 |
| Lane, RW | 1 |
| Borzelleca, JF | 1 |
| Schumacher, JM | 1 |
| Eroschenko, VP | 3 |
| Phillips, DE | 2 |
| Uphouse, L | 1 |
| Eckols, K | 1 |
| Emerich, D | 1 |
| Bondy, SC | 1 |
| Hudson, PM | 1 |
| Herr, DW | 1 |
| Gallus, JA | 1 |
| Chen, PH | 1 |
| Marbury, GD | 1 |
| Karoum, F | 1 |
| Mactutus, CF | 1 |
1 review available for chlordecone and Action Tremor
| Article | Year |
|---|---|
Comparative toxicology of chlordecone (Kepone) in humans and experimental animals.
Topics: Animals; Body Weight; Carcinogens; Chlordecone; Endocrine Glands; Female; Humans; Infertility, Male; | 1982 |
18 other studies available for chlordecone and Action Tremor
| Article | Year |
|---|---|
Acute chlordecone toxicity in rats: a relationship between tremor and ATPase activities.
Topics: Adenosine Triphosphatases; Animals; Brain; Ca(2+) Mg(2+)-ATPase; Chlordecone; Dose-Response Relation | 1981 |
Chlordecone-induced tremor: quantification and pharmacological analysis.
Topics: Analysis of Variance; Animals; Apomorphine; Chlordecone; Dose-Response Relationship, Drug; Harmine; | 1982 |
Studies on the possible sites of chlordecone-induced tremor in rats.
Topics: Animals; Chlordecone; Dimethyl Sulfoxide; Drug Interactions; Insecticides; Male; Psychotropic Drugs; | 1983 |
Effects of chlordecone exposure on brain neurotransmitters: possible involvement of the serotonin system in chlordecone-elicited tremor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Temperature; Brain Chemistry; Chlordecone; Corpus Stri | 1984 |
Estradiol-chlordecone (Kepone) interactions: additive effect of combinations for uterotropic and embryo implantation functions.
Topics: Animals; Chlordecone; Drug Interactions; Embryo Implantation; Estradiol; Estrogen Antagonists; Femal | 1996 |
Chlordecone intoxication in man. I. Clinical observations.
Topics: Chemical Phenomena; Chemistry; Chlordecone; Environmental Exposure; Eye Movements; Humans; Insectici | 1978 |
Short-term chlordecone toxicity in rats including effects on reproduction, pathological organ changes, and their reversibility.
Topics: Adrenal Glands; Animals; Body Weight; Chlordecone; Female; Insecticides; Liver; Male; Organ Size; Ra | 1979 |
Acute, subchronic, and chronic toxicity of chlordecone.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Chlordecone; Dogs; Dose-Response Relat | 1979 |
Transmission and scanning electron microscopic study of chlordecone (Kepone) induced changes in the male mouse choroid plexus.
Topics: Animals; Cell Membrane; Chlordecone; Choroid Plexus; Epithelium; Estradiol; Insecticides; Male; Mice | 1985 |
Effects of the insecticide chlordecone on the ultrastructure of mouse skeletal muscle.
Topics: Animals; Chlordecone; Insecticides; Mice; Mice, Inbred BALB C; Mitochondria, Muscle; Muscles; Tremor | 1985 |
Serotonin receptors in striatum after chlordecone treatment of adult female rats.
Topics: Animals; Binding, Competitive; Brain Chemistry; Chlordecone; Corpus Striatum; Female; Insecticides; | 1986 |
Inhibition of ornithine decarboxylase alters neurological responsiveness to a tremorigen.
Topics: Animals; Behavior, Animal; Chlordecone; Eflornithine; Male; Ornithine; Ornithine Decarboxylase Inhib | 1986 |
5,5-Diphenylhydantoin antagonizes neurochemical and behavioral effects of p,p'-DDT but not of chlordecone.
Topics: Animals; Brain Chemistry; Brain Stem; Caudate Nucleus; Chlordecone; DDT; Hippocampus; Hydroxyindolea | 1986 |
Pharmacological modification of tremor and enhanced acoustic startle by chlordecone and p,p'-DDT.
Topics: Acoustic Stimulation; Animals; Calcium; Chlordecone; DDT; Injections, Intraventricular; Insecticides | 1987 |
Effect of chlordecone (Kepone) on the rat brain concentration of 3-methoxy-4-hydroxyphenylglycol: evidence for a possible involvement of the norepinephrine system in chlordecone-induced tremor.
Topics: Animals; Brain Stem; Caudate Nucleus; Cerebellum; Chlordecone; Glycols; Hypothalamus; Hypothermia; I | 1985 |
An electron microscopic study of alterations in mouse peripheral nerve and skeletal muscle after chlordecone exposure.
Topics: Animals; Chlordecone; Female; Insecticides; Male; Mice; Mice, Inbred BALB C; Microscopy, Electron; M | 1985 |
Studies on the mechanism of chlordecone-induced tremor in rats.
Topics: Animals; Apomorphine; Ataxia; Chlordecone; Dose-Response Relationship, Drug; Harmine; Insecticides; | 1985 |
Evaluation of long-term consequences in behavioral and/or neural function following neonatal chlordecone exposure.
Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Chlordecone; Dextroamphetamine; Female; Ha | 1985 |