Page last updated: 2024-11-08

chloramphenicol and Thalassemias

chloramphenicol has been researched along with Thalassemias in 6 studies

Amphenicol: Chloramphenicol and its derivatives.

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TRUMAN, JT1
TALBOT, NB1
WEINER, M1
Konstantopoulos, K1
Avlami, A1
Demarongona, K1
Sideris, G1
Rekoumi, L1
Stefanou, J1
Voskaridou, E1
Loukopoulos, D1
Mathé, G1
Amiel, JL1
Schwarzenberg, L1
Choay, J1
Trolard, P1
Schneider, M1
Hayat, M1
Schlumberger, JR1
Jasmin, C1
Engh, CA1
Hughes, JL1
Abrams, RC1
Bowerman, JW1
Goodman, JR1
Hall, SG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Trial of Immunosuppression in Aplastic Anemia Patients With Refractory Pancytopenia or Suboptimal Hematologic Response After h-ATG/CsA Treatment[NCT00065260]Phase 254 participants (Actual)Interventional2003-11-06Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Robust Hematologic Recovery With Reticulocyte or Platelet Count

Number of participants with robust hematologic recovery with reticulocyte or platelet count ≥ 50,000/uL (NCT00065260)
Timeframe: 6 months

InterventionParticipants (Count of Participants)
r-ATG /Cyclosporine9
Alemtuzumab (Campath-1H)9

Percentage of Cumulative Incidence of Clonal Evolution in Participants

Percent of cumulative incidence of clonal evolution in participants to either paroxysmal nocturnal hemoglobinuria (PNH), myelodysplasia or acute leukemia. (NCT00065260)
Timeframe: 3 years

InterventionPercentage of Cumulative Incidence (Number)
r-ATG /Cyclosporine16
Alemtuzumab (Campath-1H)5

Percentage of Cumulative Incidence of Relapse in Participants

Percentage of cumulative incidence of relapse of disease in participants (NCT00065260)
Timeframe: 3 year

Interventionpercentage of cumulative incidence (Number)
r-ATG /Cyclosporine19
Alemtuzumab (Campath-1H)9

Participants no Longer Meeting Criteria for Severe Aplastic Anemia.

Number of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment at 6 months (NCT00065260)
Timeframe: 6 months

,
Interventionparticipants (Number)
No ResponsePartial ResponseComplete Response
Alemtuzumab (Campath-1H)1790
r-ATG /Cyclosporine1890

Percentage of Participants no Longer Meeting Criteria for Severe Aplastic Anemia.

Percentage of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment (NCT00065260)
Timeframe: 3 months and 6 months

,
Interventionpercentage of participants (Number)
3 Months6 Months
Alemtuzumab (Campath-1H)1937
r-ATG /Cyclosporine1933

Other Studies

6 other studies available for chloramphenicol and Thalassemias

ArticleYear
ANEMIA IN CHILDHOOD.
    Clinical pediatrics, 1964, Volume: 3

    Topics: Anemia; Anemia, Aplastic; Child; Chloramphenicol; Classification; Diagnosis, Differential; Erythrocy

1964
FACTORS INFLUENCING THE CLINICAL USE OF CHELATES IN IRON STORAGE DISEASE.
    Annals of the New York Academy of Sciences, 1964, Oct-07, Volume: 119

    Topics: Calcium; Chelating Agents; Chloramphenicol; Drug Therapy; Edetic Acid; Humans; Iron; Lymphoma, Non-H

1964
Bacteroides fragilis arthritis in a sickle cell-thalassaemia patient.
    Scandinavian journal of infectious diseases, 1994, Volume: 26, Issue:4

    Topics: Adult; Anemia, Sickle Cell; Arthritis, Infectious; Bacteroides fragilis; Bacteroides Infections; Chl

1994
Bone marrow graft in man after conditioning by antilymphocytic serum.
    British medical journal, 1970, Apr-18, Volume: 2, Issue:5702

    Topics: Acute Disease; Adolescent; Adult; Agranulocytosis; Antilymphocyte Serum; Bone Marrow Transplantation

1970
Osteomyelitis in the patient with sickle-cell disease.
    The Journal of bone and joint surgery. American volume, 1971, Volume: 53, Issue:1

    Topics: Ampicillin; Anemia, Sickle Cell; Child; Child, Preschool; Chloramphenicol; Escherichia coli Infectio

1971
Accumulation of iron in mitochondria of erythroblasts.
    British journal of haematology, 1967, Volume: 13, Issue:3

    Topics: Anemia, Hemolytic; Anemia, Sideroblastic; Bone Marrow Examination; Chloramphenicol; Erythrocytes; Gl

1967