chloramphenicol has been researched along with Thalassemia in 6 studies
Amphenicol: Chloramphenicol and its derivatives.
Thalassemia: A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TRUMAN, JT | 1 |
| TALBOT, NB | 1 |
| WEINER, M | 1 |
| Konstantopoulos, K | 1 |
| Avlami, A | 1 |
| Demarongona, K | 1 |
| Sideris, G | 1 |
| Rekoumi, L | 1 |
| Stefanou, J | 1 |
| Voskaridou, E | 1 |
| Loukopoulos, D | 1 |
| Mathé, G | 1 |
| Amiel, JL | 1 |
| Schwarzenberg, L | 1 |
| Choay, J | 1 |
| Trolard, P | 1 |
| Schneider, M | 1 |
| Hayat, M | 1 |
| Schlumberger, JR | 1 |
| Jasmin, C | 1 |
| Engh, CA | 1 |
| Hughes, JL | 1 |
| Abrams, RC | 1 |
| Bowerman, JW | 1 |
| Goodman, JR | 1 |
| Hall, SG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Immunosuppression in Aplastic Anemia Patients With Refractory Pancytopenia or Suboptimal Hematologic Response After h-ATG/CsA Treatment[NCT00065260] | Phase 2 | 54 participants (Actual) | Interventional | 2003-11-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of participants with robust hematologic recovery with reticulocyte or platelet count ≥ 50,000/uL (NCT00065260)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| r-ATG /Cyclosporine | 9 |
| Alemtuzumab (Campath-1H) | 9 |
Percent of cumulative incidence of clonal evolution in participants to either paroxysmal nocturnal hemoglobinuria (PNH), myelodysplasia or acute leukemia. (NCT00065260)
Timeframe: 3 years
| Intervention | Percentage of Cumulative Incidence (Number) |
|---|---|
| r-ATG /Cyclosporine | 16 |
| Alemtuzumab (Campath-1H) | 5 |
Percentage of cumulative incidence of relapse of disease in participants (NCT00065260)
Timeframe: 3 year
| Intervention | percentage of cumulative incidence (Number) |
|---|---|
| r-ATG /Cyclosporine | 19 |
| Alemtuzumab (Campath-1H) | 9 |
Number of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment at 6 months (NCT00065260)
Timeframe: 6 months
| Intervention | participants (Number) | ||
|---|---|---|---|
| No Response | Partial Response | Complete Response | |
| Alemtuzumab (Campath-1H) | 17 | 9 | 0 |
| r-ATG /Cyclosporine | 18 | 9 | 0 |
Percentage of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment (NCT00065260)
Timeframe: 3 months and 6 months
| Intervention | percentage of participants (Number) | |
|---|---|---|
| 3 Months | 6 Months | |
| Alemtuzumab (Campath-1H) | 19 | 37 |
| r-ATG /Cyclosporine | 19 | 33 |
6 other studies available for chloramphenicol and Thalassemia
| Article | Year |
|---|---|
ANEMIA IN CHILDHOOD.
Topics: Anemia; Anemia, Aplastic; Child; Chloramphenicol; Classification; Diagnosis, Differential; Erythrocy | 1964 |
FACTORS INFLUENCING THE CLINICAL USE OF CHELATES IN IRON STORAGE DISEASE.
Topics: Calcium; Chelating Agents; Chloramphenicol; Drug Therapy; Edetic Acid; Humans; Iron; Lymphoma, Non-H | 1964 |
Bacteroides fragilis arthritis in a sickle cell-thalassaemia patient.
Topics: Adult; Anemia, Sickle Cell; Arthritis, Infectious; Bacteroides fragilis; Bacteroides Infections; Chl | 1994 |
Bone marrow graft in man after conditioning by antilymphocytic serum.
Topics: Acute Disease; Adolescent; Adult; Agranulocytosis; Antilymphocyte Serum; Bone Marrow Transplantation | 1970 |
Osteomyelitis in the patient with sickle-cell disease.
Topics: Ampicillin; Anemia, Sickle Cell; Child; Child, Preschool; Chloramphenicol; Escherichia coli Infectio | 1971 |
Accumulation of iron in mitochondria of erythroblasts.
Topics: Anemia, Hemolytic; Anemia, Sideroblastic; Bone Marrow Examination; Chloramphenicol; Erythrocytes; Gl | 1967 |