chloramphenicol and Shock, Septic studies

Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.

Research Excerpts

Excerpt	Relevance	Reference
"These data show that acute renal failure in meningococcemia presents high mortality rate associated to shock; 80% of the survivors recover renal function; and bilateral cortical necrosis occurred in one patient in this series."	1.30	Outcome of acute renal failure in meningococcemia. ( Marotto, MS; Marotto, PC; Seguro, AC; Sztajnbok, J, 1997)
"The monthly admissions for typhoid to Goroka Base Hospital showed a peak in 1988."	1.29	Typhoid in the highlands of Papua New Guinea 1984-1990: a hospital-based perspective. ( Richens, J, 1995)
"Neonatal meningitis is characterized by unusual clinical manifestations caused by unusual organisms (with a marked predominance of gram-negative organisms), a poor prognosis due to the failure of antibiotics to penetrate the blood-brain barrier, and frequent complications (ventriculitis, hydrocephalus, and brain damage)."	1.27	Purulent meningitis in the newborn. ( Karan, S, 1986)
"In nine patients in anaerobic septic shock, five of them with hepatic injury compatible with sepsis liver failure, hematic chloramphenicol concentration was determined at 5 minutes, 1, 2, 3 and 6 hours after intravenous administration of the first of three daily dose (50 mg/k/day); in the hepatic failure group the procedure was repeated with the next dose, previous attempt of haemodynamic compensation with two hours dopamine (3-10 mcg/k/min."	1.27	[Drug metabolism in the septic liver: conclusions about the pharmacokinetics of chloramphenicol]. ( Dana, R; Flores, C; Jmelnitzky, AC; Lauri, IH; Moday, MC; Vitale, A, 1985)

Timeframe	Studies, this research(%)	All Research%
pre-1990	41 (93.18)	18.7374
1990's	3 (6.82)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors	Studies
BUTT, JH	1
FLESHLER, B	1
BOOKRAJIAN, EN	1
KIMURA, Y	1
TAKAHASHI, R	1
HOSAKA, M	1
TAKEFUJI, H	1
SCARPACI, FL	1
SMITH, EH	1
VARGAS, LL	1
HAZARD, J	1
GENTILINI, M	1
BLAIR, E	1
HENNING, G	1
HORNICK, R	1
COWLEY, RA	1
HARRIS, JD	1
WILSON, L	1
COLEMAN, BD	1
Hoffman, SL	1
Woodward, TE	1
Hornick, RB	1
Punjabi, NH	1
Greisman, SE	1
Baldwin, DG	1
Henry, RL	1
Levin, FR	1
Paulus, TE	1
Warford, LR	1
Guggenbichler, JP	1
Tielemans, C	1
Herbaut, C	1
Dratwa, M	1
Marotto, MS	1
Marotto, PC	1
Sztajnbok, J	1
Seguro, AC	1
Richens, J	1
Hopkin, DA	2
Vavros, B	1
Urbásková, P	1
Pitcairn, M	1
Schuler, J	1
Erve, PR	1
Holtzman, S	1
Schumer, W	1
Hyslop, NE	1
Swartz, MN	1
Bunin, KV	1
Brodov, LE	1
Shapkin, VI	1
Komnova, ZD	1
Kozáková, M	1
Nakamura, K	1
Arimoto, T	1
Yoneda, Y	1
Iki, Y	1
Suga, T	1
Mochizuki, S	1
Ito, K	1
Niki, I	1
Bausher, JC	1
Baker, RC	1
del Solar, A	1
Gómez Rogers, C	1
Garrido, J	1
Reyes, J	1
Karan, S	1
Jmelnitzky, AC	1
Moday, MC	1
Dana, R	1
Flores, C	1
Vitale, A	1
Lauri, IH	1
McHenry, MC	1
Motsay, GJ	1
Petersdorf, RG	1
Beaty, HN	1
Wittels, W	1
Murray, JD	1
Fleming, PC	1
Anglin, CS	1
Steele, JC	1
Fujiwara, MW	1
Marshall, BR	1
Hepler, JK	1
Jinguji, MS	1
Mokgokong, ET	1
Szendröi, Z	1
Sacca, S	1
Rózsa, L	1
Verebélyi, A	1
Chow, AW	1
Bushkell, LL	1
Yoshikawa, TT	1
Guze, LB	1
Moyer, JH	1
Mills, LC	1
Josey, WE	1
Farrar, WE	1
Mingrino, F	1
Ortali, V	1
Rossi, F	1
Lorincz, AB	1
Kikuchi, F	1
Clark, DM	1
Anderson, GV	1
Chalmers, JP	1
Tiller, DJ	1

Article	Year
THERAPY OF ACUTE BACTERIAL GASTROENTERITIS. The Medical clinics of North America, 1963, Volume: 47 Topics: Anti-Bacterial Agents; Chloramphenicol; Dehydration; Diarrhea; Gastroenteritis; Humans; Kanamycin; M	1963
Bacteremic shock due to gram-negative bacilli. Some concepts of pathogenesis and management based on recent developments. Geriatrics, 1969, Volume: 24, Issue:4 Topics: Animals; Bacteroides Infections; Chloramphenicol; Enterobacter; Escherichia coli Infections; Gentami	1969

Article	Year
SEPTIC ABORTION WITH BACTEREMIC SHOCK. The Journal of the Medical Society of New Jersey, 1963, Volume: 60 Topics: Abortion, Septic; Chloramphenicol; Female; Humans; Hydrocortisone; Metaraminol; Norepinephrine; Oxyg	1963
[SHOCK-LIKE SYMPTOMS CAUSED BY DRUGS AND THEIR TREATMENT. (1) BASIC PRINCIPLES]. Jibi inkoka Otolaryngology, 1963, Volume: 35 Topics: Adrenocorticotropic Hormone; Aminosalicylic Acid; Aminosalicylic Acids; Anaphylaxis; Anti-Bacterial	1963
[CASES OF SHOCK-LIKE CONDITIONS. (2)]. Jibi inkoka Otolaryngology, 1963, Volume: 35 Topics: Adolescent; Anti-Bacterial Agents; Antibiotics, Antitubercular; Chloramphenicol; Cocaine; Cyanosis;	1963
SNAKE BITE. Rhode Island medical journal, 1964, Volume: 47 Topics: Antivenins; Benzoates; Blood Pressure; Blood Pressure Determination; Blood Transfusion; Chlorampheni	1964
[COLIBACILLARY SEPTICEMIA AND BACTEREMIA IN ADULTS. APROPOS OF 14 CASES OF SEPTICEMIA]. La Presse medicale, 1964, Aug-29, Volume: 72 Topics: Abortion, Septic; Bacteremia; Chloramphenicol; Cholangitis; Colistin; Escherichia coli Infections; G	1964
HYPOTHERMIA IN BACTEREMIC SHOCK. Archives of surgery (Chicago, Ill. : 1960), 1964, Volume: 89 Topics: Alcaligenes; Bacteroides; Chloramphenicol; Enterobacter; Escherichia coli Infections; Humans; Hypogl	1964
GRAM-NEGATIVE SEPTICAEMIA: A REPORT OF THIRTY CASES. The Medical journal of Australia, 1965, Jan-02, Volume: 1, Issue:1 Topics: Acute Kidney Injury; Adolescent; Chloramphenicol; Drug Resistance; Drug Resistance, Microbial; Drug	1965
SEPTIC SHOCK IN PREGNANCY. Obstetrics and gynecology, 1964, Volume: 24 Topics: Acidosis; Acute Kidney Injury; Chloramphenicol; Communicable Diseases; Drug Therapy; Female; Humans;	1964
Toxic-shock syndrome. The Journal of the Arkansas Medical Society, 1980, Volume: 77, Issue:7 Topics: Adolescent; Child; Chloramphenicol; Female; Humans; Male; Menstruation; Shock, Septic; Syndrome; Tam	1980
[Purulent meningitis in children. II. Treatment and prognosis]. Padiatrie und Padologie, 1982, Volume: 17, Issue:1 Topics: Ampicillin; Child; Child, Preschool; Chloramphenicol; Cortisone; Electrolytes; Fluid Therapy; Fosfom	1982
Toxic shock syndrome in a menstruating woman : a case report and review. Acta clinica Belgica, 1982, Volume: 37, Issue:2 Topics: Acute Kidney Injury; Adult; Chloramphenicol; Female; Humans; Menstruation; Shock, Septic; Staphyloco	1982
Outcome of acute renal failure in meningococcemia. Renal failure, 1997, Volume: 19, Issue:6 Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Chlorampheni	1997
Typhoid in the highlands of Papua New Guinea 1984-1990: a hospital-based perspective. Papua and New Guinea medical journal, 1995, Volume: 38, Issue:4 Topics: Adult; Age Distribution; Algorithms; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory	1995
Too rapid destruction of gram-negative organisms. Lancet (London, England), 1977, Sep-17, Volume: 2, Issue:8038 Topics: Chloramphenicol; Gentamicins; Humans; Salmonella typhi; Sepsis; Shock, Septic	1977
Frapper fort ou frapper doucement: a gram-negative dilemma. Lancet (London, England), 1978, Dec-02, Volume: 2, Issue:8101 Topics: Animals; Antitoxins; Bacterial Toxins; Chloramphenicol; Chlorpromazine; Cortisone; Endotoxins; Guine	1978
[Pneumococci resistant to tetracycline and chloramphenicol as a cause of fatal pleuropneumonia]. Vnitrni lekarstvi, 1976, Volume: 22, Issue:4 Topics: Aged; Chloramphenicol; Drug Resistance, Microbial; Humans; Klebsiella Infections; Klebsiella pneumon	1976
Glucocorticoid and antibiotic effect on experimental gram-negative bacteremic shock. Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:8 Topics: Ampicillin; Animals; Chloramphenicol; Dexamethasone; Escherichia coli; Gentamicins; Humans; Male; Pe	1975
Bacterial meningitis. Postgraduate medicine, 1975, Volume: 58, Issue:3 Topics: Ampicillin; Bacterial Infections; Blood Coagulation Disorders; Chloramphenicol; Diagnosis, Different	1975
[Possibilities of development of infectious-toxic shock in some infectious diseases]. Terapevticheskii arkhiv, 1975, Volume: 47, Issue:8 Topics: Aged; Ampicillin; Chloramphenicol; Drug Combinations; Dysentery; Humans; Male; Middle Aged; Oleandom	1975
[Sub-shock state brought on by epidermic test for chloramphenicol (author's transl)]. Ceskoslovenska dermatologie, 1976, Volume: 51, Issue:2 Topics: Anaphylaxis; Chloramphenicol; Female; Humans; Middle Aged; Shock, Septic	1976
[A case of salmonella colitis complicated with delirium, disseminated intravascular coagulation and multiple organ failure]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1990, Dec-10, Volume: 79, Issue:12 Topics: Adult; Chloramphenicol; Colitis; Delirium; Disseminated Intravascular Coagulation; Humans; Imipenem;	1990
Early prognostic indicators in acute meningococcemia: implications for management. Pediatric emergency care, 1986, Volume: 2, Issue:3 Topics: Child, Preschool; Chloramphenicol; Combined Modality Therapy; Dopamine; Emergencies; Epinephrine; Fe	1986
[Toxic shock. Staphylococcus aureus toxemia]. Revista medica de Chile, 1987, Volume: 115, Issue:3 Topics: Adult; Cefotaxime; Cesarean Section; Chloramphenicol; Female; Humans; Penicillins; Shock, Septic; St	1987
Purulent meningitis in the newborn. Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 1986, Volume: 2, Issue:1 Topics: Ampicillin; Anti-Bacterial Agents; Chloramphenicol; Gentamicins; Humans; Infant, Newborn; Injections	1986
[Drug metabolism in the septic liver: conclusions about the pharmacokinetics of chloramphenicol]. Acta gastroenterologica Latinoamericana, 1985, Volume: 15, Issue:1 Topics: Chloramphenicol; Humans; Kinetics; Liver; Regression Analysis; Shock, Septic	1985
Gram negative septic shock. Experimental and clinical studies. International surgery, 1970, Volume: 54, Issue:2 Topics: Adolescent; Adult; Aged; Ampicillin; Animals; Arteriovenous Anastomosis; Blood Pressure; Capillary P	1970
The role of antibiotics, vasoactive drugs and steroids in Gram-negative bacteremia. Annals of the New York Academy of Sciences, 1967, Sep-27, Volume: 145, Issue:2 Topics: Adrenal Cortex Hormones; Adult; Ampicillin; Anti-Bacterial Agents; Cephalothin; Chloramphenicol; Col	1967
[Antibiotics and corticosteroids in the corticosteroids in the treatment of burns]. Wiener klinische Wochenschrift, 1971, Dec-31, Volume: 83, Issue:52 Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Burns; Chloramphenicol; Dexamethasone; Gentamicins;	1971
Acute bacterial meningitis in childhood: an outline of management. Clinical pediatrics, 1972, Volume: 11, Issue:8 Topics: Adrenal Cortex Hormones; Age Factors; Ampicillin; Anti-Bacterial Agents; Anticonvulsants; Blood Tran	1972
Fatal Streptococcus pyogenes septicemia associated with an intrauterine device. Obstetrics and gynecology, 1973, Volume: 41, Issue:1 Topics: Adult; Cervix Uteri; Chloramphenicol; Dexamethasone; Endometritis; Endometrium; Female; Humans; Intr	1973
Treatment of septicaemic shock in gynaecology and obstetrics. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Oct-27, Volume: 47, Issue:42 Topics: Abortion, Septic; Adrenal Cortex Hormones; Bicarbonates; Blood Transfusion; Chloramphenicol; Digoxin	1973
Problems in atypical purulent pyelonephritis. International urology and nephrology, 1972, Volume: 4, Issue:1 Topics: Acute Disease; Adult; Chloramphenicol; Humans; Middle Aged; Nephrectomy; Oxytetracycline; Pyelonephr	1972
Case report. Haemophilus parainfluenzae epiglottitis with meningitis and bacteremia in an adult. The American journal of the medical sciences, 1974, Volume: 267, Issue:6 Topics: Adult; Chloramphenicol; Epiglottis; Haemophilus; Haemophilus Infections; Humans; Laryngitis; Male; M	1974
Vasopressors for treating shock. Postgraduate medicine, 1974, Volume: 56, Issue:2 Topics: Bacteria; Chloramphenicol; Epinephrine; Humans; Isoproterenol; Metaraminol; Methoxamine; Morphine; M	1974
Cephaloridine in septic abortion. Comparison with a conventional combined antibiotic regimen in a conservative program of management. American journal of obstetrics and gynecology, 1970, Jan-15, Volume: 106, Issue:2 Topics: Abortion, Septic; Adolescent; Adult; Cephaloridine; Chloramphenicol; Escherichia coli Infections; Fe	1970
[Current clinical and therapeutic aspects of meningococcal infections]. Recenti progressi in medicina, 1971, Volume: 51, Issue:3 Topics: Acute Disease; Chloramphenicol; Heparin; Humans; Meningitis, Meningococcal; Meningococcal Infections	1971
[What is your diagnosis?]. Medizinische Klinik, 1971, Nov-05, Volume: 66, Issue:45 Topics: Adult; Amputation, Surgical; Blood Transfusion; Chloramphenicol; Female; Forearm Injuries; Fractures	1971
Septic abortion. Postgraduate medicine, 1971, Volume: 49, Issue:6 Topics: Abortion, Septic; Administration, Oral; Bacterial Infections; Chloramphenicol; Curettage; Dose-Respo	1971
[2 cases of shock possibly due to chloramphenicol]. Sanfujinka no jissai. Practice of gynecology and obstetrics, 1969, Volume: 18, Issue:10 Topics: Adult; Chloramphenicol; Female; Humans; Shock, Septic	1969
Perinatal mortality and amnionitis in a general hospital population. Obstetrics and gynecology, 1968, Volume: 31, Issue:5 Topics: Adult; Amnion; Birth Weight; Chloramphenicol; Female; Fetal Death; Hospitalization; Humans; Infant M	1968
Effects of treatment on the mortality rate in septicaemia. British medical journal, 1969, May-10, Volume: 2, Issue:5653 Topics: Adrenal Cortex Hormones; Adult; Aged; Chloramphenicol; Digitalis Glycosides; Female; Humans; Kanamyc	1969

chloramphenicol and Shock, Septic

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