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chloramphenicol and Optic Neuritis

chloramphenicol has been researched along with Optic Neuritis in 35 studies

Amphenicol: Chloramphenicol and its derivatives.

Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).

Research Excerpts

ExcerptRelevanceReference
"The authors present a case of optic neuritis in an adult patient who had been self-prescribing extraordinarily large dosages of chloramphenicol for chronic prostatitis over several years."7.77Chloramphenicol--not so innocuous: a case of optic neuritis. ( Billson, FA; Fung, AT; Hudson, B, 2011)
"Peripheral and optic neuritis developed in a girl with hemoglobin SC disease, during long-term high-dose treatment of Salmonella osteomyelitis with chloramphenicol."7.65Peripheral and optic neuritis in a patient with hemoglobin SC disease during treatment of salmonella osteomyelitis with chloramphenicol. ( Charache, S; Finkelstein, D; Lietman, PS; Scott, J, 1977)
"The authors present a case of optic neuritis in an adult patient who had been self-prescribing extraordinarily large dosages of chloramphenicol for chronic prostatitis over several years."3.77Chloramphenicol--not so innocuous: a case of optic neuritis. ( Billson, FA; Fung, AT; Hudson, B, 2011)
"Peripheral and optic neuritis developed in a girl with hemoglobin SC disease, during long-term high-dose treatment of Salmonella osteomyelitis with chloramphenicol."3.65Peripheral and optic neuritis in a patient with hemoglobin SC disease during treatment of salmonella osteomyelitis with chloramphenicol. ( Charache, S; Finkelstein, D; Lietman, PS; Scott, J, 1977)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199033 (94.29)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (5.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Long, SS1
Fung, AT1
Hudson, B1
Billson, FA1
LASKY, MA1
PINCUS, MH1
KATLAN, NR1
COLE, JG1
COLE, HG1
JANOFF, LA1
BUBLIK, AA1
LIETMAN, PS2
DISANTAGNESE, PA1
WONG, V1
MOTOHASHI, T1
FUJIWARA, T1
KEITH, CG1
STEIDL, PE1
Cocke, JG2
Lessell, S1
Jaeger, W1
Geller, A1
Gilles, F1
Shwachman, H1
Charache, S1
Finkelstein, D1
Scott, J1
Haile, CA1
Nakamura, Y1
Ogata, J1
Watanabe, T1
Segawa, J1
Ramilo, O1
Kinane, BT1
McCracken, GH1
Begg, IS1
Small, M1
White, AM1
Schulz, G1
Tateishi, J2
Dralands, L1
VanOmmen, RA1
Kuroda, S1
Yokoyama, S1
Murayama, E1
Miyakawa, T1
Sumiyoshi, S1
Deshimaru, M1
Sugita, K1
Inoue, K1
Mannen, T1
Tsukagoshi, H1
Toyokura, Y1
Cogan, DG1
Truman, JT1
Smith, TR1
Tamura, K1
Ohta, M1
Tabira, T1
Kuroiwa, Y1
Lieberman, TW1
von Wasielewski, E1
Bredehorst, HG1
Chang, N1
Giles, CL1
Gregg, RH1
Brown, RE1
Geppert, LJ1
Nielsen, EL1
Kittel, V1
Cornelius, C1
Lamba, PA1
Sood, NN1
Moorthy, SS1
Faarbaek, O1

Reviews

3 reviews available for chloramphenicol and Optic Neuritis

ArticleYear
Ocular effects of prolonged systemic drug administration. (Corticosteroids, chloramphenicol and anovulatory agents).
    Diseases of the nervous system, 1968, Volume: 29, Issue:3

    Topics: Animals; Arthritis, Rheumatoid; Cataract; Chloramphenicol; Contraceptives, Oral; Cystic Fibrosis; Ey

1968
[Significant side effects of antibiotics].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1971, Volume: 77

    Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Ch

1971
Optic neuritis and chloramphenicol.
    American journal of diseases of children (1960), 1966, Volume: 112, Issue:1

    Topics: Adolescent; Child, Preschool; Chloramphenicol; Female; Humans; Optic Neuritis

1966

Other Studies

32 other studies available for chloramphenicol and Optic Neuritis

ArticleYear
50 Years Ago in The Journal of Pediatrics: Visual Disturbances in Cystic Fibrosis following Chloramphenicol Administration.
    The Journal of pediatrics, 2016, Volume: 168

    Topics: Anti-Bacterial Agents; Child; Chloramphenicol; Cystic Fibrosis; History, 20th Century; Humans; Optic

2016
Chloramphenicol--not so innocuous: a case of optic neuritis.
    BMJ case reports, 2011, Mar-03, Volume: 2011

    Topics: Adult; Anti-Bacterial Agents; Chloramphenicol; Humans; Male; Optic Neuritis

2011
Bilateral optic neuritis following chloramphenicol therapy.
    Journal of the American Medical Association, 1953, Apr-18, Volume: 151, Issue:16

    Topics: Chloramphenicol; Disease; Endocarditis; Endocarditis, Bacterial; Eye; Humans; Optic Nerve; Optic Ner

1953
A toxic ocular manifestation of chloramphenicol therapy; report of a case of optic neuritis.
    American journal of ophthalmology, 1957, Volume: 44, Issue:1

    Topics: Chloramphenicol; Disease; Eye; Head; Humans; Neuritis; Optic Nerve; Optic Nerve Diseases; Optic Neur

1957
[ON A CASE OF OPTIC NEURITIS].
    Archivos de oftalmologia de Buenos Aires, 1963, Volume: 38

    Topics: Anti-Bacterial Agents; Betamethasone; Chloramphenicol; Focal Infection; Focal Infection, Dental; Opt

1963
OPTIC NEURITIS IN CYSTIC FIBROSIS OF THE PANCREAS. ROLE OF CHLORAMPHENICOL THERAPY.
    JAMA, 1964, Sep-21, Volume: 189

    Topics: Child; Chloramphenicol; Cystic Fibrosis; Diagnosis; Humans; Ophthalmoscopy; Optic Neuritis; Patholog

1964
[VARIOUS PHASES OF OPHTHALMOPLEGIA (1)].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1964, Volume: 18

    Topics: Carotid Artery Diseases; Chloramphenicol; Drug Therapy; Ethmoid Sinus; Herpes Zoster; Humans; Intrac

1964
OPTIC ATROPHY INDUCED BY CHLORAMPHENICOL.
    The British journal of ophthalmology, 1964, Volume: 48

    Topics: Adolescent; Anti-Bacterial Agents; Bronchiectasis; Child; Chloramphenicol; Cystic Fibrosis; Drug The

1964
[BILATERAL OPTIC NEURITIS CAUSED BY THE PROLONGED THERAPEUTIC USE OF CHLORAMPHENICOL].
    L'union medicale du Canada, 1965, Volume: 94

    Topics: Chloramphenicol; Hydrocortisone; Optic Neuritis; Research

1965
Chloramphenicol optic neuritis. Apparent protective effects of very high daily doses of pyridoxine and cyanocobalamin.
    American journal of diseases of children (1960), 1967, Volume: 114, Issue:4

    Topics: Child; Chloramphenicol; Cystic Fibrosis; Female; Humans; Optic Neuritis; Pyridoxine; Vitamin B 12

1967
Toxic metabolic disorders of myelin --ophthalmological features.
    Bulletin de la Societe belge d'ophtalmologie, 1983, Volume: 208 Pt 1

    Topics: Adolescent; Adult; Aged; Amblyopia; Child; Child, Preschool; Chloramphenicol; Contraceptives, Oral,

1983
[Acquired colour-vision-deficiencies caused by side-effects of pharmacotherapy (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1977, Volume: 170, Issue:3

    Topics: Antipsychotic Agents; Chloramphenicol; Chloroquine; Chlorpropamide; Color Vision Defects; Contracept

1977
Degeneration of fasciculus gracilis in cystic fibrosis.
    Neurology, 1977, Volume: 27, Issue:2

    Topics: Adolescent; Autopsy; Child, Preschool; Chloramphenicol; Cystic Fibrosis; Humans; Nerve Degeneration;

1977
Peripheral and optic neuritis in a patient with hemoglobin SC disease during treatment of salmonella osteomyelitis with chloramphenicol.
    The Johns Hopkins medical journal, 1977, Volume: 140, Issue:3

    Topics: Child; Chloramphenicol; Female; Hemoglobin, Sickle; Hemoglobinopathies; Humans; Neuritis; Optic Neur

1977
Chloramphenicol toxicity.
    Southern medical journal, 1977, Volume: 70, Issue:4

    Topics: Adult; Anemia, Aplastic; Angioedema; Chloramphenicol; Drug Hypersensitivity; Erythropoiesis; Fever;

1977
[Myelo-optico-neuropathy probably due to chloramphenicol--an autopsy case].
    Rinsho shinkeigaku = Clinical neurology, 1976, Volume: 16, Issue:1

    Topics: Abdomen; Chloramphenicol; Humans; Male; Middle Aged; Myelitis; Optic Neuritis; Pain

1976
Chloramphenicol neurotoxicity.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:5

    Topics: Child; Chloramphenicol; Humans; Male; Optic Neuritis; Paresthesia; Pyridoxine; Time Factors; Visual

1988
Propionate and acetate excretion in chloramphenicol toxicity.
    Lancet (London, England), 1968, Sep-21, Volume: 2, Issue:7569

    Topics: Acetates; Chloramphenicol; Fatty Acids, Nonesterified; Female; Folic Acid; Humans; Middle Aged; Neur

1968
[Comparative studies on the toxicity of tetracyclines and chloramphenicol in the treatment of nonspecific bronchopulmonary infections].
    Zeitschrift fur Erkrankungen der Atmungsorgane mit Folia bronchologica, 1972, Volume: 136, Issue:2

    Topics: Administration, Oral; Adult; Bronchiectasis; Bronchitis; Chloramphenicol; Drug Eruptions; Female; Ga

1972
Comparative study of neurotoxicity of clioquinol, ethambutol, isoniazid and chloramphenicol in dogs.
    Folia psychiatrica et neurologica japonica, 1974, Volume: 28, Issue:1

    Topics: Abdomen; Administration, Oral; Animals; Axons; Chloramphenicol; Clioquinol; Dogs; Ethambutol; Isonia

1974
[Harmful effects of common drugs on the visual apparatus. Anti-infective drugs. B. Antibiotics].
    Bulletin de la Societe belge d'ophtalmologie, 1972, Volume: 160, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Blindness; Cephalosporins; Child; Child, Preschool;

1972
Untoward effects of antimicrobial agents on major organ systems.
    The Medical clinics of North America, 1974, Volume: 58, Issue:3

    Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia;

1974
[Autopsy case of neural complication of chloramphenicol administration].
    Rinsho shinkeigaku = Clinical neurology, 1974, Volume: 14, Issue:4

    Topics: Anemia, Aplastic; Brain; Cerebellar Diseases; Cerebellum; Chloramphenicol; Female; Humans; Middle Ag

1974
[Retrobulbar optic neuritis and polyneuritis due to prolonged chloramphenicol therapy].
    Rinsho shinkeigaku = Clinical neurology, 1973, Volume: 13, Issue:4

    Topics: Aged; Chloramphenicol; Female; Humans; Lung Abscess; Male; Middle Aged; Myelin Sheath; Optic Neuriti

1973
[Case of chloramphenicol optico-neuropathy].
    Rinsho shinkeigaku = Clinical neurology, 1973, Volume: 13, Issue:2

    Topics: Adult; Chloramphenicol; Humans; Leg; Male; Movement Disorders; Muscular Atrophy; Optic Neuritis; Per

1973
Optic neuropathy, chloramphenicol, and infantile genetic agranulocytosis.
    Investigative ophthalmology, 1973, Volume: 12, Issue:7

    Topics: Agranulocytosis; Autopsy; Bacterial Infections; Child, Preschool; Chloramphenicol; Choroid; Female;

1973
[Optic and peripheral neuritis following chloramphenicol therapy (author's transl)].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1973, Volume: 62, Issue:12

    Topics: Adolescent; Adult; Aged; Chloramphenicol; Female; Humans; Lung Diseases; Male; Middle Aged; Neuritis

1973
Optic neuritis with prolonged use of chloramphenicol. Case report and relationship to fundus changes in cystic fibrosis.
    The Journal of pediatrics, 1966, Volume: 68, Issue:1

    Topics: Child; Chloramphenicol; Cystic Fibrosis; Female; Fundus Oculi; Humans; Optic Neuritis; Pseudomonas a

1966
[Optic neuritis as a complication to treatment of cystic fibrosis with chloramphenicol].
    Ugeskrift for laeger, 1972, Oct-30, Volume: 134, Issue:44

    Topics: Child; Child, Preschool; Chloramphenicol; Cystic Fibrosis; Female; Humans; Optic Atrophy; Optic Neur

1972
[Optic nerve lesions due to chloramphenicol].
    Klinische Monatsblatter fur Augenheilkunde, 1969, Volume: 155, Issue:1

    Topics: Age Factors; Child, Preschool; Chloramphenicol; Female; Humans; Infant; Male; Ophthalmoscopy; Optic

1969
Retinopathy due to chloramphenicol.
    Scottish medical journal, 1968, Volume: 13, Issue:5

    Topics: Child, Preschool; Chloramphenicol; Exudates and Transudates; Female; Fundus Oculi; Humans; Optic Neu

1968
[Bilateral optic neuritis after treatment with chloramphenicol. A case and a survey].
    Ugeskrift for laeger, 1968, Aug-08, Volume: 130, Issue:32

    Topics: Chloramphenicol; Humans; Male; Middle Aged; Optic Neuritis; Pyuria

1968