Page last updated: 2024-11-08

chloramphenicol and Necrosis

chloramphenicol has been researched along with Necrosis in 32 studies

Amphenicol: Chloramphenicol and its derivatives.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"These data show that acute renal failure in meningococcemia presents high mortality rate associated to shock; 80% of the survivors recover renal function; and bilateral cortical necrosis occurred in one patient in this series."1.30Outcome of acute renal failure in meningococcemia. ( Marotto, MS; Marotto, PC; Seguro, AC; Sztajnbok, J, 1997)
"25 hr following injection, and these values declined with a terminal half-life of 2."1.29Pharmacokinetics and tolerability of chloramphenicol in budgerigars (Melopsittacus undulatus). ( Itoh, N; Okada, H, 1993)
"In a case of pediatric Whipple disease confined to the central nervous system, white matter lesions initially appeared as areas of very low signal intensity on T1-weighted MR images and as areas of hyperintensity on proton density-weighted and T2-weighted images, and showed slight peripheral enhancement on delayed contrast-enhanced T1-weighted images."1.29Whipple disease confined to the central nervous system in childhood. ( Bonnier, C; Duprez, TP; Dutrieux, JL; Evrard, P; Gadisseux, JF; Grandin, CB; Thauvoy, CW, 1996)
"Necrotizing fasciitis is a soft-tissue infection, usually polymicrobial, that causes necrosis of fascia and subcutaneous tissue while sparing skin and muscle."1.28Cervical necrotizing fasciitis: an uncommon sequela to dental infection. ( Kunpittaya, S; Moss, RM; Sorasuchart, A, 1990)
"Necrotising fasciitis of the genitalia still carries a high risk of mortality and morbidity, frequently necessitating long periods of hospitalisation and repeated surgical procedures."1.27Fournier's gangrene: necrotising fasciitis of the male genitalia. ( Arndt, TC; Bahlmann, JC; Fourie, IJ, 1983)
"Treatment with prednisone, immunosuppressants, and aspirin was unsuccessful."1.26Bilateral acute retinal necrosis. ( Price, FW; Schlaegel, TF, 1980)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199023 (71.88)18.7374
1990's4 (12.50)18.2507
2000's1 (3.13)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Faveret, PLS1
Santiago, F1
Vatakuti, S1
Pennings, JL1
Gore, E1
Olinga, P1
Groothuis, GM1
Przyklenk, K1
Undyala, VV1
Wider, J1
Sala-Mercado, JA1
Gottlieb, RA1
Mentzer, RM1
Lacativa, AM1
Loyola, AM1
Sousa, CJ1
SALM, R1
ZUCCHI, C1
ROSENBAUM, JL1
BLACK, MW1
RUTHER, H1
Jorge, MT1
Malaque, C1
Ribeiro, LA1
Fan, HW1
Cardoso, JL1
Nishioka, SA1
Sano-Martins, IS1
França, FO1
Kamiguti, AS1
Theakston, RD1
Warrell, DA1
Iaremchuk, AIa1
Mendel', AK1
Karaban, NI1
Bahlmann, JC1
Fourie, IJ1
Arndt, TC1
Price, FW1
Schlaegel, TF1
Itoh, N1
Okada, H1
Duprez, TP1
Grandin, CB1
Bonnier, C1
Thauvoy, CW1
Gadisseux, JF1
Dutrieux, JL1
Evrard, P1
Marotto, MS1
Marotto, PC1
Sztajnbok, J1
Seguro, AC1
Long, JR1
Truscott, RB1
Griffith, GL1
Luce, EA1
Castro, JA1
de Ferreyra, EC1
de Castro, CR1
de Fenos, OM1
Gram, TE1
Reagan, RL1
Guarino, AM1
Ometov, VK1
Khasabov, LM1
Mumme, C1
Moss, RM1
Kunpittaya, S1
Sorasuchart, A1
Mohr, HJ1
Gordon, SL1
Greer, RB1
Craig, CP1
Bernier, G1
Filion, R1
Malo, R1
Phaneuf, JB1
LaMont, JT1
Eikmeier, H1
Toledo-Pereyra, LH1
Raij, L1
Simmons, RL1
Najarian, JS1
Padeĭskaia, EN1
Berezina, EK1
Rein, JM1
Cosman, B1
Erausquin, J1
Muruzábal, M1
Rea, WJ1
Wyrick, WJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Routine vs. Clinically-Directed Antibiotic Treatment in Snake Bite With Local Envenomation: a Randomised Controlled Trial[NCT02570347]Phase 4130 participants (Anticipated)Interventional2016-04-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for chloramphenicol and Necrosis

ArticleYear
Surgical Management of Penile Lesions Secondary to Foreign Body Reaction: A Case Report and Systematic Review.
    Aesthetic surgery journal, 2018, Jun-13, Volume: 38, Issue:7

    Topics: Adult; Body Modification, Non-Therapeutic; Brazil; Chloramphenicol; Collagenases; Debridement; Drug

2018
Postoperative juandice.
    The Surgical clinics of North America, 1974, Volume: 54, Issue:3

    Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju

1974

Trials

1 trial available for chloramphenicol and Necrosis

ArticleYear
Failure of chloramphenicol prophylaxis to reduce the frequency of abscess formation as a complication of envenoming by Bothrops snakes in Brazil: a double-blind randomized controlled trial.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 2004, Volume: 98, Issue:9

    Topics: Abscess; Administration, Oral; Adolescent; Adult; Animals; Anti-Bacterial Agents; Bothrops; Brazil;

2004

Other Studies

29 other studies available for chloramphenicol and Necrosis

ArticleYear
Classification of Cholestatic and Necrotic Hepatotoxicants Using Transcriptomics on Human Precision-Cut Liver Slices.
    Chemical research in toxicology, 2016, Mar-21, Volume: 29, Issue:3

    Topics: Acetaminophen; Aged; Benzofurans; Bile Acids and Salts; Chloramphenicol; Chlorpromazine; Cholestasis

2016
Acute induction of autophagy as a novel strategy for cardioprotection: getting to the heart of the matter.
    Autophagy, 2011, Volume: 7, Issue:4

    Topics: Animals; Apoptosis; Autophagy; Chloramphenicol; Disease Models, Animal; Models, Biological; Myocardi

2011
Histological evaluation of bone response to pediatric endodontic pastes: an experimental study in guinea pig.
    Brazilian dental journal, 2012, Volume: 23, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Biocompatible Materials; Bone Resorption;

2012
Acute necrosis of the liver following chloramphenicol therapy.
    Edinburgh medical journal, 1953, Volume: 60, Issue:7

    Topics: Chloramphenicol; Humans; Liver; Necrosis

1953
[Trypsin detergence of suppurative necrotic superficial lesions].
    Archivio italiano di chirurgia, 1960, Volume: 86

    Topics: Chloramphenicol; Communicable Diseases; Necrosis; Skin; Skin Diseases; Soft Tissue Injuries; Trypsin

1960
HEMODIALYSIS FOR ACUTE CARBON TETRACHLORIDE POISONING.
    The Journal of the Albert Einstein Medical Center, Philadelphia, 1964, Volume: 12

    Topics: Barbiturates; Carbon Tetrachloride Poisoning; Chloramphenicol; Kidney Diseases; Kidneys, Artificial;

1964
[On the debridement of necrotic tissue defects and varicose leg ulcers with proteolytic enzymes].
    Die Medizinische Welt, 1962, Jan-20, Volume: 3

    Topics: Chloramphenicol; Debridement; Dermatologic Agents; Humans; Necrosis; Peptide Hydrolases; Trypsin; Va

1962
[Clinicomorphological characteristics of suppurative wounds treated with iruksol].
    Klinicheskaia meditsina, 1982, Volume: 60, Issue:6

    Topics: Adult; Amidohydrolases; Chloramphenicol; Clostridium perfringens; Drug Combinations; Drug Evaluation

1982
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 24-1984. Pancytopenia and fever in a renal-transplant recipient.
    The New England journal of medicine, 1984, Jun-14, Volume: 310, Issue:24

    Topics: Bone Marrow; Chloramphenicol; Disseminated Intravascular Coagulation; Histoplasmosis; Humans; Kidney

1984
Fournier's gangrene: necrotising fasciitis of the male genitalia.
    British journal of urology, 1983, Volume: 55, Issue:1

    Topics: Adult; Aged; Chloramphenicol; Fasciitis; Gangrene; Genital Diseases, Male; Humans; Male; Metronidazo

1983
Bilateral acute retinal necrosis.
    American journal of ophthalmology, 1980, Volume: 89, Issue:3

    Topics: Adult; Chloramphenicol; Female; Fluorescein Angiography; Hemorrhage; Humans; Necrosis; Photography;

1980
Pharmacokinetics and tolerability of chloramphenicol in budgerigars (Melopsittacus undulatus).
    The Journal of veterinary medical science, 1993, Volume: 55, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chloramphenicol; Creatine K

1993
Whipple disease confined to the central nervous system in childhood.
    AJNR. American journal of neuroradiology, 1996, Volume: 17, Issue:8

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Brain Diseases; Cerebellar Diseases; Child, Preschool;

1996
Outcome of acute renal failure in meningococcemia.
    Renal failure, 1997, Volume: 19, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Chlorampheni

1997
Necrotic enteritis in broiler chickens. III. Reproduction of the disease.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1976, Volume: 40, Issue:1

    Topics: Animals; Chickens; Chloramphenicol; Clostridium Infections; Clostridium perfringens; Enteritis; Necr

1976
Massive skin necrosis in Rocky Mountain spotted fever.
    Southern medical journal, 1978, Volume: 71, Issue:11

    Topics: Child; Chloramphenicol; Debridement; Disseminated Intravascular Coagulation; Female; Heparin; Humans

1978
Mechanism of chloramphenicol prevention of carbon tetrachloride-induced liver damage.
    Experimental and molecular pathology, 1978, Volume: 28, Issue:3

    Topics: Animals; Body Temperature; Carbon Tetrachloride; Chloramphenicol; Lipid Metabolism; Liver; Male; Mic

1978
[Ulcerative-necrotic skin lesions caused by application of synthomycin emulsion].
    Vestnik dermatologii i venerologii, 1978, Issue:3

    Topics: Chloramphenicol; Emulsions; Humans; Male; Middle Aged; Necrosis; Skin; Skin Ulcer; Streptomycin

1978
[Agranulocytosis from the point of view of the general practitioner. In memory of Edgar Reye (30.5.1882-11.12.1945) (author's translation)].
    MMW, Munchener medizinische Wochenschrift, 1976, Mar-05, Volume: 118, Issue:10

    Topics: Adult; Agranulocytosis; Aminopyrine; Chloramphenicol; Diagnosis, Differential; Family Practice; Fema

1976
Cervical necrotizing fasciitis: an uncommon sequela to dental infection.
    The Annals of otology, rhinology, and laryngology, 1990, Volume: 99, Issue:8

    Topics: Adult; Bacterial Infections; Chloramphenicol; Clindamycin; Fasciitis; Gingival Diseases; Humans; Mal

1990
[Experimental studies on the etiology and pathogenesis of pyelonephritis].
    Beitrage zur pathologischen Anatomie und zur allgemeinen Pathologie, 1969, Volume: 138, Issue:4

    Topics: Animals; Chloramphenicol; Escherichia coli Infections; Glycoproteins; Glycosaminoglycans; Histocytoc

1969
Recurrent osteomyelitis. Report of four cases culturing L-form variants of Staphylococci.
    The Journal of bone and joint surgery. American volume, 1971, Volume: 53, Issue:6

    Topics: Adolescent; Adult; Cephalosporins; Chloramphenicol; Chronic Disease; Culture Media; Enterococcus fae

1971
[Necrotic enteritis in broilers. II. Characteristics of the strains of Clostridium perfringens isolated].
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1974, Volume: 38, Issue:3

    Topics: Animals; Antitoxins; Chickens; Chloramphenicol; Clostridium perfringens; Culture Media; Enteritis; G

1974
[Aseptic necroses in newborn puppies following i.m. injections].
    Berliner und Munchener tierarztliche Wochenschrift, 1973, Nov-01, Volume: 86, Issue:21

    Topics: Animals; Animals, Newborn; Chloramphenicol; Dog Diseases; Dogs; Injections, Intramuscular; Necrosis

1973
Role of exdotoxin and bacteria in long-term survival of preserved small-bowel allografts.
    Surgery, 1974, Volume: 76, Issue:3

    Topics: Animals; Ascitic Fluid; Bacteria; Blood; Chloramphenicol; Disseminated Intravascular Coagulation; Do

1974
[Chemotherapy of experimental chronic salmonellosis in mice with dioxidine, quinoxidine, levomycetin and ampicillin].
    Antibiotiki, 1972, Volume: 17, Issue:3

    Topics: Ampicillin; Animals; Chloramphenicol; Dioxins; Mice; Necrosis; Quinoxalines; Salmonella; Salmonella

1972
Bacteroides necrotizing fasciitis of the upper extremity. Case report.
    Plastic and reconstructive surgery, 1971, Volume: 48, Issue:6

    Topics: Adult; Anaerobiosis; Arm; Bacteroides; Bacteroides Infections; Chloramphenicol; Fascia; Female; Huma

1971
Necrosis of cementum induced by root canal treatments in the molar teeth of rats.
    Archives of oral biology, 1967, Volume: 12, Issue:10

    Topics: Animals; Chloramphenicol; Dental Cementum; Dental Pulp Exposure; Dentin; Mandible; Molar; Necrosis;

1967
Necrotizing fasciitis.
    Annals of surgery, 1970, Volume: 172, Issue:6

    Topics: Adolescent; Adult; Aged; Arteriosclerosis; Calcium; Child; Child, Preschool; Chloramphenicol; Debrid

1970