chloramphenicol and Myocardial Ischemia studies

chloramphenicol and Myocardial Ischemia

Amphenicol: Chloramphenicol and its derivatives.

Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).

Research Excerpts

Excerpt	Relevance	Reference
"Chloramphenicol is an inhibitor of mitochondrial protein synthesis and is also an inhibitor of a subset of cytochrome P450 monooxygenases (CYPs)."	1.32	Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. ( Gottlieb, RA; Granville, DJ; Gustafsson, AB; Huang, C; Sayen, MR; Takeuchi, C; Tashakkor, B; Wentworth, P; Yeager, M, 2004)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

3 (100.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Granville, DJ	1
Tashakkor, B	1
Takeuchi, C	1
Gustafsson, AB	1
Huang, C	1
Sayen, MR	1
Wentworth, P	1
Yeager, M	1
Gottlieb, RA	2
Leslie, M	1
He, H	1
Chen, M	1
Scheffler, NK	1
Gibson, BW	1
Spremulli, LL	1

Studies

Granville, DJ

Tashakkor, B

Takeuchi, C

Gustafsson, AB

Huang, C

Sayen, MR

Wentworth, P

Yeager, M

Gottlieb, RA

Leslie, M

He, H

Chen, M

Scheffler, NK

Gibson, BW

Spremulli, LL

Other Studies

3 other studies available for chloramphenicol and Myocardial Ischemia

Article	Year
Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2004, Feb-03, Volume: 101, Issue:5 Topics: Animals; Chloramphenicol; Cimetidine; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrom	2004
Hampering a heartbreaker. Antibiotic might stem injury from heart attack. Science of aging knowledge environment : SAGE KE, 2004, Jan-28, Volume: 2004, Issue:4 Topics: Animals; Chloramphenicol; Enzyme Inhibitors; Humans; Myocardial Infarction; Myocardial Ischemia; Myo	2004
Phosphorylation of mitochondrial elongation factor Tu in ischemic myocardium: basis for chloramphenicol-mediated cardioprotection. Circulation research, 2001, Aug-31, Volume: 89, Issue:5 Topics: Adenosine Triphosphate; Animals; Chloramphenicol; Enzyme Inhibitors; Genistein; Ischemic Preconditio	2001

Article

Year

Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors.

Proceedings of the National Academy of Sciences of the United States of America, 2004, Feb-03, Volume: 101, Issue:5

Topics: Animals; Chloramphenicol; Cimetidine; Creatine Kinase; Cytochrome P-450 Enzyme Inhibitors; Cytochrom

2004

Hampering a heartbreaker. Antibiotic might stem injury from heart attack.

Science of aging knowledge environment : SAGE KE, 2004, Jan-28, Volume: 2004, Issue:4

Topics: Animals; Chloramphenicol; Enzyme Inhibitors; Humans; Myocardial Infarction; Myocardial Ischemia; Myo

2004

Phosphorylation of mitochondrial elongation factor Tu in ischemic myocardium: basis for chloramphenicol-mediated cardioprotection.

Circulation research, 2001, Aug-31, Volume: 89, Issue:5

Topics: Adenosine Triphosphate; Animals; Chloramphenicol; Enzyme Inhibitors; Genistein; Ischemic Preconditio

2001