chloramphenicol has been researched along with Mucopolysaccharidosis I in 1 studies
Amphenicol: Chloramphenicol and its derivatives.
Mucopolysaccharidosis I: Systemic lysosomal storage disease caused by a deficiency of alpha-L-iduronidase (IDURONIDASE) and characterized by progressive physical deterioration with urinary excretion of DERMATAN SULFATE and HEPARAN SULFATE. There are three recognized phenotypes representing a spectrum of clinical severity from severe to mild: Hurler syndrome, Hurler-Scheie syndrome and Scheie syndrome (formerly mucopolysaccharidosis V). Symptoms may include DWARFISM; hepatosplenomegaly; thick, coarse facial features with low nasal bridge; corneal clouding; cardiac complications; and noisy breathing.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chloramphenicol is a peptidyl transferase inhibitor able to induce readthrough and is efficient in cross the blood brain barrier." | 5.39 | Chloramphenicol enhances IDUA activity on fibroblasts from mucopolysaccharidosis I patients. ( Artigalás, OA; Baldo, G; Giugliani, R; Lagranha, VL; Matte, U; Mayer, FQ; Schwartz, IV, 2013) |
| "Chloramphenicol is a peptidyl transferase inhibitor able to induce readthrough and is efficient in cross the blood brain barrier." | 1.39 | Chloramphenicol enhances IDUA activity on fibroblasts from mucopolysaccharidosis I patients. ( Artigalás, OA; Baldo, G; Giugliani, R; Lagranha, VL; Matte, U; Mayer, FQ; Schwartz, IV, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mayer, FQ | 1 |
| Artigalás, OA | 1 |
| Lagranha, VL | 1 |
| Baldo, G | 1 |
| Schwartz, IV | 1 |
| Matte, U | 1 |
| Giugliani, R | 1 |
1 other study available for chloramphenicol and Mucopolysaccharidosis I
| Article | Year |
|---|---|
Chloramphenicol enhances IDUA activity on fibroblasts from mucopolysaccharidosis I patients.
Topics: Cells, Cultured; Chloramphenicol; Codon, Nonsense; Codon, Terminator; Enzyme Inhibitors; Fibroblasts | 2013 |