Page last updated: 2024-11-08

chloramphenicol and Malaria

chloramphenicol has been researched along with Malaria in 13 studies

Amphenicol: Chloramphenicol and its derivatives.

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
"The objective of this study was to determine if the current dosage regimen for chloramphenicol CAP administered to children with severe malaria SM for presumptive treatment of concomitant bacterial meningitis achieves steady state plasma CAP concentrations within the reported therapeutic range of 10-25 mg/l."7.73Chloramphenicol pharmacokinetics in African children with severe malaria. ( Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR, 2006)
"A young women was treated with intravenous quinine and chloramphenicol for suspected severe malaria and/or typhoid fever."7.68Quinine blindness. ( Dutta, TK; Lalloo, D; Moyia, N; Naraqi, S; Okem, S; Zzferio, B, 1992)
") seizure prophylactic dose of fosphenytoin (18 mg kg-1 phenytoin sodium equivalents) were concomitantly administered to 15 African children with malaria."5.10Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration. ( Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR; Otieno, GO, 2002)
"The objective of this study was to determine if the current dosage regimen for chloramphenicol CAP administered to children with severe malaria SM for presumptive treatment of concomitant bacterial meningitis achieves steady state plasma CAP concentrations within the reported therapeutic range of 10-25 mg/l."3.73Chloramphenicol pharmacokinetics in African children with severe malaria. ( Kokwaro, GO; Muchohi, SN; Newton, CR; Ogutu, BR, 2006)
"A young women was treated with intravenous quinine and chloramphenicol for suspected severe malaria and/or typhoid fever."3.68Quinine blindness. ( Dutta, TK; Lalloo, D; Moyia, N; Naraqi, S; Okem, S; Zzferio, B, 1992)
"The monthly admissions for typhoid to Goroka Base Hospital showed a peak in 1988."1.29Typhoid in the highlands of Papua New Guinea 1984-1990: a hospital-based perspective. ( Richens, J, 1995)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's2 (15.38)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ogutu, BR2
Newton, CR2
Muchohi, SN2
Otieno, GO1
Kokwaro, GO2
RUIZ-SANCHEZ, F1
QUEZADA, M1
PAREDES, M2
CASILLAS, J2
RIEBELING, R1
IMBODEN, CA1
COOPER, WC1
COATNEY, GR1
JEFFERY, GM1
RUIZ SANCHEZ, F1
RIEBELING, OB1
Puri, SK1
Dutta, GP1
Richens, J1
Duggan, MB1
Beyer, L1
Feigl, A1
Feigl, D1
Shem-Tov, A1
Brish, M1
Rotem, J1
Naraqi, S1
Okem, S1
Moyia, N1
Dutta, TK1
Zzferio, B1
Lalloo, D1
Macmillan, AL1
Geddes, AM1
Warhurst, DC1
Robinson, BL1

Reviews

1 review available for chloramphenicol and Malaria

ArticleYear
Antibiotics in the chemotherapy of malaria.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1982, Volume: 26

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Chloramphenicol; Clindamycin; Erythromycin; Gentami

1982

Trials

1 trial available for chloramphenicol and Malaria

ArticleYear
Phenytoin pharmacokinetics and clinical effects in African children following fosphenytoin and chloramphenicol coadministration.
    British journal of clinical pharmacology, 2002, Volume: 54, Issue:6

    Topics: Anti-Bacterial Agents; Anticonvulsants; Area Under Curve; Cefotaxime; Child, Preschool; Chlorampheni

2002

Other Studies

11 other studies available for chloramphenicol and Malaria

ArticleYear
Chloramphenicol in malaria.
    The American journal of tropical medicine and hygiene, 1952, Volume: 1, Issue:6

    Topics: Chloramphenicol; Humans; Malaria

1952
Studies in human malaria. XXIX. Trials of aureomycin, chloramphenicol, penicillin, and dihydrostreptomycin against the Chesson strain of Plasmodium vivax.
    Journal. National Malaria Society (U.S.), 1950, Volume: 9, Issue:4

    Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Chloramphenicol; Chlortetracycline; Dermatologic

1950
[Two cases of malaria treated with chloramphenicol].
    Revista. Asociacion Medica Mexicana, 1951, Oct-25, Volume: 31, Issue:638

    Topics: Chloramphenicol; Humans; Malaria

1951
Chloramphenicol pharmacokinetics in African children with severe malaria.
    Journal of tropical pediatrics, 2006, Volume: 52, Issue:4

    Topics: Africa; Anti-Bacterial Agents; Child; Child, Preschool; Chloramphenicol; Female; Humans; Infant; Inj

2006
Typhoid in the highlands of Papua New Guinea 1984-1990: a hospital-based perspective.
    Papua and New Guinea medical journal, 1995, Volume: 38, Issue:4

    Topics: Adult; Age Distribution; Algorithms; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory

1995
Enteric fever in young Yoruba children.
    Archives of disease in childhood, 1975, Volume: 50, Issue:1

    Topics: Age Factors; Anemia; Arthritis, Infectious; Blood Transfusion; Child, Preschool; Chloramphenicol; Di

1975
Congenital atrial flutter.
    Chest, 1975, Volume: 67, Issue:5

    Topics: Atrial Flutter; Chloramphenicol; Chloroquine; Digoxin; Electrocardiography; Female; Fetal Diseases;

1975
Quinine blindness.
    Papua and New Guinea medical journal, 1992, Volume: 35, Issue:4

    Topics: Adult; Ascorbic Acid; Blindness; Chloramphenicol; Cyclandelate; Dexamethasone; Drug Therapy, Combina

1992
Generalised pustular drug rash.
    Dermatologica, 1973, Volume: 146, Issue:5

    Topics: Adult; Aged; Biguanides; Chloramphenicol; Chloroquine; Cross Reactions; Digoxin; Drug Eruptions; Fur

1973
Imported infections. Unexplained fever.
    British medical journal, 1974, Nov-16, Volume: 4, Issue:5941

    Topics: Africa; Asia; Brucellosis; Chloramphenicol; Chloroquine; Fever; Humans; Leishmaniasis, Visceral; Liv

1974
Cytotoxic agents and haemozoin pigment in malaria parasites (Plasmodium berghei).
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1971, Jul-08, Volume: 10, Issue:13

    Topics: Animals; Antineoplastic Agents; Azaserine; Chloramphenicol; Chloroquine; Cycloheximide; Cytoplasm; D

1971