Compounds > chloramphenicol
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chloramphenicol and Liver Diseases

chloramphenicol has been researched along with Liver Diseases in 43 studies

Amphenicol: Chloramphenicol and its derivatives.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"During the course of typhoid fever, the usual histologic finding of the liver is "nonspecific reactive hepatitis."2.42Typhoid fever as a rare cause of hepatic, splenic, and bone marrow granulomas. ( Aki, H; Aktuglu, Y; Mert, A; Ozaras, R; Ozturk, R; Tabak, F, 2004)
" Pharmacokinetics of selected anti-infective agents are altered in hepatic disease, necessitating careful monitoring and dosage titration to avoid enhanced drug concentrations and risk of toxicity."2.39Anti-infective agents and hepatic disease. ( Tschida, SJ; Vance-Bryan, K; Zaske, DE, 1995)
" The consequences of liver damage for withdrawal times and dosage schedules are discussed."1.27The pharmacokinetic behaviour of chloramphenicol in liver-damaged mini-pigs. ( Kroker, R, 1985)
" The extent to which hemodialysis removes chloramphenicol from the plasma does not appear significant enough to warrant routine dosage adjustment."1.26Chloramphenicol hemodialysis clearance. ( Blouin, RA; Bustrack, JA; Dutro, MP; Erwin, WG; Rowse, KL, 1980)
" The half-life of chloramphenicol (t 1/2) was increased in the various liver disorders, the metabolic clearance rate (MCR) and apparent volume of distribution (Vd) were decreased and the area under the time - concentrations curve (AUC) showed an increase."1.26Pharmacokinetic study of chloramphenicol in patients with liver disease. ( Datta, DV; Mathur, VS; Narang, AP; Nath, N, 1981)
"One patient with fatal disseminated intravascular coagulation and enteric fever is also presented."1.26Enteric fever: a clinicopathologic study of 104 cases. ( Nasrallah, SM; Nassar, VH, 1978)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199040 (93.02)18.7374
1990's2 (4.65)18.2507
2000's1 (2.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PEDERZINI, A1
BERGONZINI, R1
FALOON, WW1
SUHRLAND, LG1
WEISBERGER, AS1
REID, JV1
WRIGHT, R1
CARROLL, R1
RAYBAUD, C1
WILSON, J1
ORSINI, A1
LEVRAT, M1
BRETTE, R1
TRUCHOT, R1
WHALLEY, PJ1
ADAMS, RH1
COMBES, B1
ROSENBAUM, JL1
BLACK, MW1
TAKAGAKI, Y1
ITO, M1
FUJIWARA, K2
MAEJIMA, M1
NAIKI, M1
TAJIMA, Y1
MACBETH, WA1
KASS, EH1
MCDERMOTT, WV1
Mert, A1
Tabak, F1
Ozaras, R1
Ozturk, R1
Aki, H1
Aktuglu, Y1
Fuglesang, J1
Bergan, T1
Lesar, TS1
Zaske, DE2
Howard, PH1
Raebel, M1
Hurley, DL1
Blouin, RA1
Erwin, WG1
Dutro, MP1
Bustrack, JA1
Rowse, KL1
Narang, AP1
Datta, DV1
Nath, N1
Mathur, VS1
Epping, J1
Fuchshofen, M1
Richter, E1
Slaughter, RL1
Pieper, JA1
Cerra, B1
Brodsky, B1
Koup, JR1
Tschida, SJ1
Vance-Bryan, K1
Aronson, AL1
Nasrallah, SM1
Nassar, VH1
Luft, FC1
Hill, MJ1
Drasar, BS1
Gralla, EJ1
Bhutta, ZA1
Naqvi, SH1
Durrani, S1
Suria, A1
Kroker, R1
Linhart, P1
Presant, CA1
Wiernik, PH1
Serpick, AA1
Hirasawa, K1
Yokoiyama, S1
Fujii, T1
Menz, HP1
Bezler, HJ1
Hartmann, I1
von Oldershausen, HF1
Havelka, J2
Havlík, J2
Moore, RD1
LaMont, JT1
Fossati, C1
Pánek, V1
Kröner, H1
Schlag, P1
Staib, W1
Gussoff, BD1
Lee, SL1
Burger, H1
Dalton, AC1
Erlinger, S1
Sakellaridis, DA1
Maillard, JN1
Benhamou, JP1

Reviews

7 reviews available for chloramphenicol and Liver Diseases

ArticleYear
Typhoid fever as a rare cause of hepatic, splenic, and bone marrow granulomas.
    Internal medicine (Tokyo, Japan), 2004, Volume: 43, Issue:5

    Topics: Aged; Biopsy, Needle; Bone Marrow Diseases; Chloramphenicol; Female; Follow-Up Studies; Granuloma; H

2004
Chloramphenicol and thiamphenicol.
    Antibiotics and chemotherapy, 1982, Volume: 31

    Topics: Animals; Biological Availability; Body Fluids; Chloramphenicol; Female; Humans; Intestinal Absorptio

1982
Antibiotics and hepatic disease.
    The Medical clinics of North America, 1982, Volume: 66, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Chloramphenicol; Clindamycin; Humans; Isoniazid; Kinetics; L

1982
Anti-infective agents and hepatic disease.
    The Medical clinics of North America, 1995, Volume: 79, Issue:4

    Topics: Anti-Infective Agents; Chloramphenicol; Clindamycin; Fluoroquinolones; Humans; Isoniazid; Liver Dise

1995
The use, misuse, and abuse of antibacterial agents.
    Modern veterinary practice, 1975, Volume: 56, Issue:6

    Topics: Administration, Oral; Anesthesia, General; Animals; Anti-Bacterial Agents; Cats; Cattle; Cattle Dise

1975
Postoperative juandice.
    The Surgical clinics of North America, 1974, Volume: 54, Issue:3

    Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju

1974
[Liver damage due to drugs. II].
    La Clinica terapeutica, 1974, Jan-31, Volume: 68, Issue:2

    Topics: Ampicillin; Antitubercular Agents; Asparaginase; Chemical and Drug Induced Liver Injury; Chloramphen

1974

Trials

2 trials available for chloramphenicol and Liver Diseases

ArticleYear
Chloramphenicol therapy of typhoid fever and its relationship to hepatic dysfunction.
    Journal of tropical pediatrics, 1991, Volume: 37, Issue:6

    Topics: Adolescent; Child; Child, Preschool; Chloramphenicol; Clinical Protocols; Drug Monitoring; Humans; I

1991
Chloramphenicol-induced hematopoietic depression: a controlled comparison with tetracycline.
    The American journal of the medical sciences, 1966, Volume: 251, Issue:1

    Topics: Chloramphenicol; Clinical Trials as Topic; Hematopoietic System; Humans; Kidney Diseases; Liver Dise

1966

Other Studies

34 other studies available for chloramphenicol and Liver Diseases

ArticleYear
[Behavior of the chloramphenicol tolerance test curve in liver disease].
    Minerva medica, 1952, Sep-24, Volume: 43, Issue:77

    Topics: Chloramphenicol; Humans; Liver Diseases; Liver Function Tests

1952
Metabolic and histologic studies in patients with and without liver disease receiving chloramphenicol and oxytetracycline.
    The Journal of laboratory and clinical medicine, 1954, Volume: 44, Issue:1

    Topics: Biochemical Phenomena; Chloramphenicol; Liver Diseases; Metabolism; Nitrogen; Oxytetracycline

1954
CHLORAMPHENICOL TOXICITY IN LIVER AND RENAL DISEASE.
    Archives of internal medicine, 1963, Volume: 112

    Topics: Anemia; Anemia, Aplastic; Ascites; Chloramphenicol; Erythropoiesis; Hematocrit; Humans; Iron Isotope

1963
CHRONIC SALMONELLOSIS.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1963, Nov-23, Volume: 37

    Topics: Anemia; Black People; Blood Protein Disorders; Child; Chloramphenicol; Eosinophilia; Fever; Hepatome

1963
ANTIBIOTICS AND HEPATIC ISCHAEMIA.
    The British journal of surgery, 1964, Volume: 51

    Topics: Anti-Bacterial Agents; Chloramphenicol; Ischemia; Liver Diseases; Penicillins; Rabbits; Research; Te

1964
[BRUCELLOSIS IN CHILDREN].
    La Medecine infantile, 1964, Volume: 71

    Topics: Bacteriological Techniques; Brucellosis; Child; Chloramphenicol; Complement Fixation Tests; Diagnosi

1964
[THE BILIARY ELIMINATION OF ANTIBIOTICS].
    Revue internationale d'hepatologie, 1964, Volume: 14

    Topics: Anti-Bacterial Agents; Bacitracin; Bile; Biliary Tract; Chloramphenicol; Dogs; Erythromycin; Hepatob

1964
TETRACYCLINE TOXICITY IN PREGNANCY. LIVER AND PANCREATIC DYSFUNCTION.
    JAMA, 1964, Aug-03, Volume: 189

    Topics: Chloramphenicol; Clinical Enzyme Tests; Escherichia coli Infections; Female; Humans; Jaundice; Jaund

1964
HEMODIALYSIS FOR ACUTE CARBON TETRACHLORIDE POISONING.
    The Journal of the Albert Einstein Medical Center, Philadelphia, 1964, Volume: 12

    Topics: Barbiturates; Carbon Tetrachloride Poisoning; Chloramphenicol; Kidney Diseases; Kidneys, Artificial;

1964
[EFFECTS OF ANTIBIOTICS AND SULFONAMIDES ON TYZZER'S DISEASE IN EXPERIMENTALLY INFECTED MICE].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1964, Volume: 158

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Chloramphenicol; Colistin; Cortisone; E

1964
TREATMENT OF HEPATIC ENCEPHALOPATHY BY ALTERATION OF INTESTINAL FLORA WITH LACTOBACILLUS ACIDOPHILUS.
    Lancet (London, England), 1965, Feb-20, Volume: 1, Issue:7382

    Topics: Amino Acid Oxidoreductases; Anti-Bacterial Agents; Bacteriological Techniques; Blood Chemical Analys

1965
The use of antimicrobial agents in patients with hepatic and renal dysfunction.
    The Surgical clinics of North America, 1982, Volume: 62, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Chloramphenicol; Drug Administration Schedul

1982
Chloramphenicol hemodialysis clearance.
    Therapeutic drug monitoring, 1980, Volume: 2, Issue:4

    Topics: Aged; Blood Proteins; Chloramphenicol; Female; Humans; Kidney Failure, Chronic; Liver Diseases; Male

1980
Pharmacokinetic study of chloramphenicol in patients with liver disease.
    European journal of clinical pharmacology, 1981, Volume: 20, Issue:6

    Topics: Acute Disease; Adult; Budd-Chiari Syndrome; Chloramphenicol; Female; Half-Life; Hepatitis; Humans; H

1981
[Enterohepatic circulation in liver diseases].
    Medizinische Klinik, 1980, Feb-01, Volume: 75, Issue:3

    Topics: Animals; Barbiturates; Bile Acids and Salts; Biotransformation; Bisacodyl; Chloramphenicol; Cholesta

1980
Chloramphenicol sodium succinate kinetics in critically ill patients.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:1

    Topics: Acute Disease; Adult; Aged; Chloramphenicol; Creatinine; Female; Humans; Hydrolysis; Individuality;

1980
Enteric fever: a clinicopathologic study of 104 cases.
    The American journal of gastroenterology, 1978, Volume: 69, Issue:1

    Topics: Adolescent; Adult; Child; Child, Preschool; Chloramphenicol; Disseminated Intravascular Coagulation;

1978
Antimicrobials in kidney and liver failure.
    American family physician, 1976, Volume: 14, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Antifungal Agents; Antitubercular Agents; Cephalosporins; Ch

1976
The normal colonic bacterial flora.
    Gut, 1975, Volume: 16, Issue:4

    Topics: Ammonia; Bacteria; Bacteroides; Bile Acids and Salts; Carcinogens; Chloramphenicol; Clostridium; Col

1975
Adverse drug reactions.
    The Veterinary clinics of North America, 1975, Volume: 5, Issue:4

    Topics: Abnormalities, Drug-Induced; Acute Kidney Injury; Agranulocytosis; Anemia, Aplastic; Anemia, Hemolyt

1975
The pharmacokinetic behaviour of chloramphenicol in liver-damaged mini-pigs.
    Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Female; Half-Life; Liver Diseases;

1985
Affinity of UDP-glucuronyl-transferase for several substrates and for chloramphenicol.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Jul-04, Volume: 163, Issue:3

    Topics: Animals; Bilirubin; Binding, Competitive; Chloramphenicol; Estradiol; Glucuronates; Glucuronosyltran

1974
Effects of phenylalanine and related compounds on serum alkaline phosphatase assay.
    Clinica chimica acta; international journal of clinical chemistry, 1971, Volume: 32, Issue:3

    Topics: Adult; Alkaline Phosphatase; Bone Diseases; Chemistry, Clinical; Chloramphenicol; Fenclonine; Humans

1971
[Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders].
    Japanese circulation journal, 1968, Volume: 32, Issue:3

    Topics: Adult; Angiotensin II; Animals; Bile Duct Neoplasms; Biliary Tract Diseases; Blood Pressure; Carbon

1968
Effect of antibiotics on Tyzzer's disease.
    The Japanese journal of experimental medicine, 1971, Volume: 41, Issue:1

    Topics: Amphotericin B; Ampicillin; Animals; Anti-Bacterial Agents; Azaguanine; Cephaloridine; Chloramphenic

1971
Effects of vitamin E on toxicoderma associated with liver damage. Case report.
    The Keio journal of medicine, 1972, Volume: 21, Issue:2

    Topics: Adult; Alkanesulfonates; Antipyrine; Aspirin; Chloramphenicol; Female; Humans; Liver Diseases; Skin

1972
[Pharmacokinetics of thiamphenicol. Behavior in a acute and chronic hepatic insufficiency].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:1

    Topics: Acetamides; Anti-Bacterial Agents; Chloramphenicol; Half-Life; Heparin; Hepatitis; Humans; Liver; Li

1974
[Functional state of liver and penetration of chloramfenicol into bile (author's transl)].
    Casopis lekaru ceskych, 1974, Jan-18, Volume: 113, Issue:3

    Topics: Adult; Bile; Chloramphenicol; Female; Humans; Liver; Liver Diseases; Middle Aged

1974
Modification of the response to Freund's adjuvant by chloramphenicol.
    Journal of the Reticuloendothelial Society, 1973, Volume: 14, Issue:1

    Topics: Animals; Antigens, Bacterial; Chloramphenicol; Complement Fixation Tests; Female; Fluorescent Antibo

1973
[Biliary excretion of chloramphenicol. IV. During peroral administration of the antibiotic in patients with normal and pathologically changed liver parenchyma].
    Casopis lekaru ceskych, 1973, Jul-20, Volume: 112, Issue:29

    Topics: Administration, Oral; Bile; Chloramphenicol; Humans; Liver; Liver Diseases

1973
[Studies concerning the relationship between the release of enzymes and electrolyte shift in the liver (author's transl)].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Volume: 162, Issue:1

    Topics: Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride Poisoning; Chloramphenicol; Dinitrophen

1974
[Pathology of photosensitivity].
    Berliner und Munchener tierarztliche Wochenschrift, 1969, Apr-01, Volume: 82, Issue:7

    Topics: Animal Diseases; Animal Feed; Animals; Chloramphenicol; Liver Diseases; Photosensitivity Disorders;

1969
Host factors and toxicity of antimicrobial agents.
    Southern medical journal, 1970, Volume: 63, Issue:7

    Topics: Age Factors; Anti-Bacterial Agents; Biliary Tract Diseases; Chloramphenicol; Drug Hypersensitivity;

1970
[The angiocholitic forms of the congenital hepatic fibrosis].
    La Presse medicale, 1969, Jul-12, Volume: 77, Issue:34

    Topics: Adolescent; Adult; Ampulla of Vater; Biliary Tract Diseases; Chloramphenicol; Cholangiography; Chola

1969