chloramphenicol has been researched along with Leukemia, Lymphoid in 19 studies
Amphenicol: Chloramphenicol and its derivatives.
Leukemia, Lymphoid: Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A population-based case-control interview study of 309 childhood leukaemia cases and 618 age and sex matched controls showed a significant dose-response relation between chloramphenicol and risk of both acute lymphocytic leukaemia (ALL) and acute non-lymphocytic leukaemia (ANLL), treatment for more than 10 days being associated with risks of 11." | 1.27 | Chloramphenicol use and childhood leukaemia in Shanghai. ( Brinton, LA; Fraumeni, JF; Gao, RN; Gao, YT; Jin, F; Linet, MS; Shu, XO, 1987) |
| "Corynebacterium equi, a known cause of pneumonitis in foals, calves, and swine, was isolated from the sputum and bronchial washings of a child with pneumonitis and leukemia." | 1.26 | Pneumonitis due to Corynebacterium equi. ( Gardner, SE; Hughes, WT; Pearson, T, 1976) |
| "First, 3 cases of aplastic anemia (chlorpromazine, chloramphenicol and probably autoantibodytypes) are discussed." | 1.25 | [Clinical-hematological demonstrations: aplastic anemia, acute leukemias, polyneuropathy in Waldenstrom's disease, acute porphyria]. ( Moeschlin, S, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DARJA, M | 1 |
| DAVY, MI | 1 |
| Klein, B | 1 |
| Bessler, H | 1 |
| Lewinski, UH | 1 |
| Cohen, AM | 1 |
| Djaldetti, M | 1 |
| Moeschlin, S | 1 |
| Hennemann, HH | 1 |
| Gardner, SE | 1 |
| Pearson, T | 1 |
| Hughes, WT | 2 |
| Shu, XO | 1 |
| Gao, YT | 1 |
| Linet, MS | 1 |
| Brinton, LA | 1 |
| Gao, RN | 1 |
| Jin, F | 1 |
| Fraumeni, JF | 2 |
| Liberman, DF | 2 |
| Roti Roti, JL | 2 |
| Lange, CS | 1 |
| Baltimore, RS | 1 |
| Dobek, AS | 1 |
| Stark, FR | 1 |
| Artenstein, MS | 1 |
| Armenian, HK | 1 |
| Lilienfeld, AM | 1 |
| Amiel, JL | 2 |
| Mathe, G | 2 |
| Schwarzenberg, L | 2 |
| Schneider, M | 2 |
| Choay, J | 2 |
| Trolard, P | 2 |
| Hayat, M | 2 |
| Schlumberger, JR | 2 |
| Jasmin, C | 2 |
| Kára, J | 1 |
| Libánský, J | 1 |
| Cerná, H | 1 |
| Novotná, O | 1 |
| Gadner, H | 1 |
| Gethmann, U | 1 |
| Jessenberger, K | 1 |
| Riehm, H | 1 |
| Squire, RA | 1 |
| Bush, M | 1 |
| Forni, A | 1 |
| Vigliani, EC | 1 |
| Pearson, TA | 1 |
| Mitchell, CA | 1 |
| Mozziconacci, P | 1 |
| Le Bouar, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Trial of Immunosuppression in Aplastic Anemia Patients With Refractory Pancytopenia or Suboptimal Hematologic Response After h-ATG/CsA Treatment[NCT00065260] | Phase 2 | 54 participants (Actual) | Interventional | 2003-11-06 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of participants with robust hematologic recovery with reticulocyte or platelet count ≥ 50,000/uL (NCT00065260)
Timeframe: 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| r-ATG /Cyclosporine | 9 |
| Alemtuzumab (Campath-1H) | 9 |
Percent of cumulative incidence of clonal evolution in participants to either paroxysmal nocturnal hemoglobinuria (PNH), myelodysplasia or acute leukemia. (NCT00065260)
Timeframe: 3 years
| Intervention | Percentage of Cumulative Incidence (Number) |
|---|---|
| r-ATG /Cyclosporine | 16 |
| Alemtuzumab (Campath-1H) | 5 |
Percentage of cumulative incidence of relapse of disease in participants (NCT00065260)
Timeframe: 3 year
| Intervention | percentage of cumulative incidence (Number) |
|---|---|
| r-ATG /Cyclosporine | 19 |
| Alemtuzumab (Campath-1H) | 9 |
Number of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment at 6 months (NCT00065260)
Timeframe: 6 months
| Intervention | participants (Number) | ||
|---|---|---|---|
| No Response | Partial Response | Complete Response | |
| Alemtuzumab (Campath-1H) | 17 | 9 | 0 |
| r-ATG /Cyclosporine | 18 | 9 | 0 |
Percentage of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment (NCT00065260)
Timeframe: 3 months and 6 months
| Intervention | percentage of participants (Number) | |
|---|---|---|
| 3 Months | 6 Months | |
| Alemtuzumab (Campath-1H) | 19 | 37 |
| r-ATG /Cyclosporine | 19 | 33 |
2 reviews available for chloramphenicol and Leukemia, Lymphoid
| Article | Year |
|---|---|
Clinical epidemiology of leukemia.
Topics: Adolescent; Age Factors; Anemia, Pernicious; Benzene; Child, Preschool; Chloramphenicol; Chromosome | 1969 |
Chemical leukemogenesis in man.
Topics: Anemia, Aplastic; Benzene; Benzene Derivatives; Bone Marrow; Bone Marrow Cells; Chloramphenicol; Hum | 1974 |
17 other studies available for chloramphenicol and Leukemia, Lymphoid
| Article | Year |
|---|---|
PULMONARY MUCORMYCOSIS WITH CULTURAL IDENTIFICATION.
Topics: Anti-Bacterial Agents; Canada; Chloramphenicol; Cortisone; Erythromycin; Geriatrics; Humans; Leukemi | 1963 |
Beneficial effect of chloramphenicol on pyrexia in patients with acute leukemia.
Topics: Adolescent; Adult; Chloramphenicol; DNA, Neoplasm; Female; Fever of Unknown Origin; Humans; Leukemia | 1980 |
[Clinical-hematological demonstrations: aplastic anemia, acute leukemias, polyneuropathy in Waldenstrom's disease, acute porphyria].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Autoantibodies; Chloramphenicol; Chlorpromazine; Cortison | 1975 |
[Septicaemia in leukaemia (author's transl)].
Topics: Adult; Amikacin; Ampicillin; Chloramphenicol; Female; Gentamicins; Humans; Immunity, Cellular; Immun | 1977 |
Pneumonitis due to Corynebacterium equi.
Topics: Adolescent; Chloramphenicol; Corynebacterium; Corynebacterium Infections; Humans; Immunosuppression | 1976 |
Chloramphenicol use and childhood leukaemia in Shanghai.
Topics: Child; Child, Preschool; China; Chloramphenicol; Dose-Response Relationship, Drug; Humans; Interview | 1987 |
Effect of chloramphenicol on the growth and viability of exponentially growing mouse leukemic cells (L5178Y).
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Survival; Chloramphenicol; Culture Media; Leukem | 1973 |
Specific G2 phase toxicity of chloramphenicol on mouse leukemic cells (L5178Y).
Topics: Animals; Cell Division; Cell Line; Cell Survival; Chloramphenicol; Leukemia, Lymphoid; Methods; Mice | 1973 |
Clinical and epidemiological correlates of Pseudomonas typing.
Topics: Aged; Agglutination Tests; Aminoglycosides; Ampicillin; Animals; Anti-Bacterial Agents; Bacteriologi | 1974 |
The distribution of incubation periods of neoplastic diseases.
Topics: Adenoma; Adolescent; Adult; Burkitt Lymphoma; Carcinoma, Bronchogenic; Child; Child, Preschool; Chlo | 1974 |
[Allogenic bone marrow graft after conditioning with only antilymphocytic serum in states of bone marrow aplasias].
Topics: Adolescent; Adult; Antilymphocyte Serum; Bone Marrow Diseases; Bone Marrow Transplantation; Child; C | 1970 |
Antileukaemic and antiviral effect of chloramphenicol and rifampicin combination in the therapy of Rauscher murine leukaemia.
Topics: Animals; Chloramphenicol; Drug Therapy, Combination; Drug Tolerance; Leukemia, Experimental; Leukemi | 1974 |
[Acute leukemia following exposure to chloramphenicol? Three case reports and review of the literature (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; | 1973 |
The therapy of canine and feline lymphosarcoma.
Topics: Ampicillin; Animals; BCG Vaccine; Cat Diseases; Cats; Chloramphenicol; Cyclophosphamide; Dog Disease | 1973 |
Bone marrow graft in man after conditioning by antilymphocytic serum.
Topics: Acute Disease; Adolescent; Adult; Agranulocytosis; Antilymphocyte Serum; Bone Marrow Transplantation | 1970 |
Aeromonas hydrophila septicemia.
Topics: Aeromonas; Child; Child, Preschool; Chloramphenicol; Female; Gentamicins; Humans; Immunosuppression | 1972 |
[Treatment of suppurative meningitis due to multiresistant bacteria].
Topics: Age Factors; Cephaloridine; Child; Chloramphenicol; Drug Resistance, Microbial; Drug Synergism; Fema | 1971 |