Page last updated: 2024-11-08

chloramphenicol and Kwashiorkor

chloramphenicol has been researched along with Kwashiorkor in 6 studies

Amphenicol: Chloramphenicol and its derivatives.

Kwashiorkor: A syndrome produced by severe protein deficiency, characterized by retarded growth, changes in skin and hair pigment, edema, and pathologic changes in the liver, including fatty infiltration, necrosis, and fibrosis. The word is a local name in Gold Coast, Africa, meaning displaced child. Although first reported from Africa, kwashiorkor is now known throughout the world, but mainly in the tropics and subtropics. It is considered to be related to marasmus. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"The binding of chloramphenicol to normal and kwashiorkor sera was investigated in vitro."7.65Chloramphenicol binding to normal and kwashiorkor sera. ( Buchanan, N; Van der Walt, LA, 1977)
" Seventeen % of the dose (range 0-51%) was recovered in urine as intact prodrug, indicating incomplete and variable bioavailability of chloramphenicol."1.29Decreased chloramphenicol clearance in malnourished Ethiopian children. ( Alemayehu, E; Ashton, M; Bolme, P; Eriksson, M; Paalzow, L, 1993)
" In consequence the mean half-life was prolonged (3."1.27Chloramphenicol pharmacokinetics in Ethiopian children of differing nutritional status. ( Bolme, P; Eriksson, M; Mariam, TW; Paalzow, L, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KONDI, A1
FOY, H1
Eriksson, M2
Paalzow, L2
Bolme, P2
Mariam, TW1
Ashton, M1
Alemayehu, E1
Buchanan, N2
Van der Walt, LA2
Hansen, JD1
Robinson, R1
Koornhot, HJ1
Poskitt, EM1

Other Studies

6 other studies available for chloramphenicol and Kwashiorkor

ArticleYear
VACUOLISATION OF EARLY ERYTHROBLASTS IN RIBOFLAVINE-DEFICIENT BABOONS AND IN MARASMUS AND KWASHIORKOR.
    Lancet (London, England), 1964, Nov-28, Volume: 2, Issue:7370

    Topics: Animals; Biomedical Research; Blood; Bone Marrow Cells; Child; Chloramphenicol; Diet; Erythroblasts;

1964
Chloramphenicol pharmacokinetics in Ethiopian children of differing nutritional status.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:6

    Topics: Administration, Oral; Child; Child, Preschool; Chloramphenicol; Ethiopia; Half-Life; Humans; Infant;

1983
Decreased chloramphenicol clearance in malnourished Ethiopian children.
    European journal of clinical pharmacology, 1993, Volume: 45, Issue:2

    Topics: Biological Availability; Child; Child, Preschool; Chloramphenicol; Ethiopia; Female; Humans; Infant;

1993
Chloramphenicol binding to normal and kwashiorkor sera.
    The American journal of clinical nutrition, 1977, Volume: 30, Issue:6

    Topics: Alpha-Globulins; Beta-Globulins; Child; Chloramphenicol; Humans; Kwashiorkor; Protein Binding; Serum

1977
Letter to the editor: Chloramphenicol metabolism in children with PCM.
    The American journal of clinical nutrition, 1976, Volume: 29, Issue:4

    Topics: Adult; Blood Proteins; Child; Chloramphenicol; Humans; Kwashiorkor; Penicillin G; Protein Binding

1976
Clinical problems related to the use of drugs in malnutrition.
    The Proceedings of the Nutrition Society, 1974, Volume: 33, Issue:3

    Topics: Child; Child Nutritional Physiological Phenomena; Chloramphenicol; Chloroquine; Drug-Related Side Ef

1974