Page last updated: 2024-11-08

chloramphenicol and Hepatitis A

chloramphenicol has been researched along with Hepatitis A in 31 studies

Amphenicol: Chloramphenicol and its derivatives.

Hepatitis A: INFLAMMATION of the LIVER in humans caused by a member of the HEPATOVIRUS genus, HUMAN HEPATITIS A VIRUS. It can be transmitted through fecal contamination of food or water.

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
DE SOSBILLA GONZALEZ, JM	1
RODRIGUEZ DEL CASTILLO, J	1
HOLLIS, WJ	1
HANISCH, LE	1
MOHNIKE, G	1
REDECHKINA, ZP	1
FUKAYA, K	1
TOMORI, G	1
ARON, SB	1
GRAEF, H	1
HALL, L	1
WHARTON, GK	1
COLBERT, JW	1
BUNGARDS, L	1
KNOWLTON, M	1
LOTT, H	1
YOUNG, RW	1
STOVALL, JC	1
CREYX, M	1
LEVY, J	1
VINCENDEAU, J	1
DAVID-CHAUSSE, J	1
Celińska, W	1
Borkowska, A	1
Hodgkinson, R	2
Dölle, W	1
Wallnöfer, H	1
Täuber, K	1
LaMont, JT	1
Benestad, HB	1
Mathé, G	1
Amiel, JL	1
Schwarzenberg, L	1
Choay, J	1
Trolard, P	1
Schneider, M	1
Hayat, M	1
Schlumberger, JR	1
Jasmin, C	1
Böttiger, LE	1
Westerholm, B	1
Stieglitz, R	1
Büttner, HH	1
Ribbe, FW	1
Amtoft, A	1
Jacobsen, N	1
Wiontzek, H	2
Wille, L	1
Griss, P	1
Vanista, J	1
Srámková, L	1
Siegmund, H	1

Clinical Trials (2)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
A Randomized Trial of Immunosuppression in Aplastic Anemia Patients With Refractory Pancytopenia or Suboptimal Hematologic Response After h-ATG/CsA Treatment[NCT00065260]	Phase 2	54 participants (Actual)	Interventional	2003-11-06	Completed
Collection of Blood, Stool, Bone Marrow and/or Tissue Samples From Subjects With Hepatitis-Associated Aplastic Anemia[NCT00050115]		9 participants (Actual)	Observational	2003-03-10	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Robust Hematologic Recovery With Reticulocyte or Platelet Count

Number of participants with robust hematologic recovery with reticulocyte or platelet count ≥ 50,000/uL (NCT00065260)
Timeframe: 6 months

Intervention	Participants (Count of Participants)
r-ATG /Cyclosporine	9
Alemtuzumab (Campath-1H)	9

Percentage of Cumulative Incidence of Clonal Evolution in Participants

Percent of cumulative incidence of clonal evolution in participants to either paroxysmal nocturnal hemoglobinuria (PNH), myelodysplasia or acute leukemia. (NCT00065260)
Timeframe: 3 years

Intervention	Percentage of Cumulative Incidence (Number)
r-ATG /Cyclosporine	16
Alemtuzumab (Campath-1H)	5

Percentage of Cumulative Incidence of Relapse in Participants

Percentage of cumulative incidence of relapse of disease in participants (NCT00065260)
Timeframe: 3 year

Intervention	percentage of cumulative incidence (Number)
r-ATG /Cyclosporine	19
Alemtuzumab (Campath-1H)	9

Participants no Longer Meeting Criteria for Severe Aplastic Anemia.

Number of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment at 6 months (NCT00065260)
Timeframe: 6 months

Intervention	participants (Number)
	No Response	Partial Response	Complete Response
Alemtuzumab (Campath-1H)	17	9	0
r-ATG /Cyclosporine	18	9	0

Percentage of Participants no Longer Meeting Criteria for Severe Aplastic Anemia.

Percentage of participants no longer meeting the criteria for severe aplastic anemia as measured by response to treatment (NCT00065260)
Timeframe: 3 months and 6 months

Intervention	percentage of participants (Number)
	3 Months	6 Months
Alemtuzumab (Campath-1H)	19	37
r-ATG /Cyclosporine	19	33

Reviews

2 reviews available for chloramphenicol and Hepatitis A

Article	Year
Postoperative juandice. The Surgical clinics of North America, 1974, Volume: 54, Issue:3 Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju	1974
Aplastic anaemia: considerations on the pathogenesis. Acta medica Scandinavica, 1974, Volume: 196, Issue:4 Topics: Anemia, Aplastic; Autoantibodies; B-Lymphocytes; Blood Platelets; Cell Division; Chloramphenicol; Ch	1974

Other Studies

29 other studies available for chloramphenicol and Hepatitis A

Article	Year
[Acute hepatitis in infectious mononucleosis; coexistence with encephalitis and facial paralysis; success of chloromycetin therapy]. Medicamenta, 1952, May-01, Volume: 10, Issue:217 Topics: Chloramphenicol; Communicable Diseases; Encephalitis; Facial Paralysis; Hepatitis; Hepatitis A; Hepa	1952
[Contribution to the treatment of parenchymatous jaundice]. Medicamenta, 1952, Aug-10, Volume: 10, Issue:222 Topics: Chloramphenicol; Hepatitis; Hepatitis A; Jaundice; Viral Vaccines	1952
Aplastic anemia; report of case following chloromycetin therapy and infectious hepatitis. The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1953, Volume: 105, Issue:10 Topics: Anemia; Anemia, Aplastic; Chloramphenicol; Hepatitis; Hepatitis A; Humans	1953
[HEPATIC COMA. DIAGNOSIS AND THERAPY]. Zeitschrift fur arztliche Fortbildung, 1963, May-15, Volume: 57 Topics: Chloramphenicol; Folic Acid; Fructose; Hepatic Encephalopathy; Hepatitis; Hepatitis A; Humans; Liver	1963
[EFFECT OF SOME FACTORS ON THE FORMATION OF THE TYPHOID-PARATYPHOID CARRIER STATE]. Zhurnal mikrobiologii, epidemiologii i immunobiologii, 1963, Volume: 40 Topics: Bacillus; Carrier State; Chloramphenicol; Chlortetracycline; Cholecystitis; Dysentery; Dysentery, Ba	1963
[CASE OF HYPERSENSITIVE HEPATITIS DUE TO PROPIONYL ERYTHROMYCIN LAURYL SULFATE]. Naika. Internal medicine, 1964, Volume: 14 Topics: Adolescent; Chemical and Drug Induced Liver Injury; Chloramphenicol; Drug Therapy; Erythromycin; Hep	1964
[STATUS OF SOME FUNCTIONS OF THE LIVER IN PATIENTS WITH TYPHOID TREATED WITH ANTIBIOTICS]. Sovetskaia meditsina, 1964, Volume: 27 Topics: Anti-Bacterial Agents; Chloramphenicol; Drug Therapy; Hepatitis; Hepatitis A; Humans; Hyperbilirubin	1964
[Aureomycin and chloromycetin in the therapy of epidemic hepatitis]. Deutsche medizinische Wochenschrift (1946), 1951, Aug-03, Volume: 76, Issue:31-32 Topics: Anti-Bacterial Agents; Chloramphenicol; Chlortetracycline; Communicable Diseases; Dermatologic Agent	1951
Chloramphenicol (chlormycetin) in the treatment of viral hepatitis. Gastroenterology, 1951, Volume: 19, Issue:1 Topics: Chlamydia Infections; Chloramphenicol; Communicable Diseases; Hepatitis; Hepatitis A; Humans	1951
Aureomycin, chloromycetin and terramycin in treatment of acute viral hepatitis. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 79, Issue:3 Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Chloramphenicol; Chlortetracycline; Communicable	1952
Viral hepatitis; report of 2 cases treated with chloramphenicol. The New Orleans medical and surgical journal, 1950, Volume: 102, Issue:11 Topics: Chloramphenicol; Communicable Diseases; Hepatitis; Hepatitis A; Hepatitis, Viral, Human; Humans	1950
[Infectious jaundice caused by paratyphoid B bacilli; favorable action of chloromycetin]. Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1950, Volume: 66, Issue:21-22 Topics: Bacillus; Chloramphenicol; Communicable Diseases; Hepatitis; Hepatitis A; Humans; Jaundice; Lacticas	1950
[Acquired failure of the hematopietic system in children]. Wiadomosci lekarskie (Warsaw, Poland : 1960), 1975, Mar-01, Volume: 28, Issue:5 Topics: Adolescent; Age Factors; Bone Marrow; Bone Marrow Diseases; Child; Child, Preschool; Chloramphenicol	1975
Infectious hepatitis and aplastic anaemia. Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707 Topics: Adult; Anemia, Aplastic; Bone Marrow Diseases; Child; Child, Preschool; Chloramphenicol; Female; Hep	1971
[Herpes simplex hepatitis in the adult]. Der Internist, 1972, Volume: 13, Issue:11 Topics: Adrenal Cortex Hormones; Adult; Antigens, Viral; Chemical and Drug Induced Liver Injury; Chloramphen	1972
[Panmyelopathy after viral hepatitis]. Medizinische Klinik, 1970, Jan-23, Volume: 65, Issue:4 Topics: Adrenocorticotropic Hormone; Adult; Antigen-Antibody Reactions; Autoimmune Diseases; Azathioprine; B	1970
The hepatitis-aplastic anaemia syndrome. The Medical journal of Australia, 1973, May-12, Volume: 1, Issue:19 Topics: Anemia, Aplastic; Chloramphenicol; Hepatitis A; Humans; Liver; Syndrome	1973
The chloramphenicol--hepatitis--aplastic anaemia syndrome. The Medical journal of Australia, 1973, May-12, Volume: 1, Issue:19 Topics: Adult; Anemia, Aplastic; Blood Cell Count; Chemical and Drug Induced Liver Injury; Child; Child, Pre	1973
Bone marrow graft in man after conditioning by antilymphocytic serum. British medical journal, 1970, Apr-18, Volume: 2, Issue:5702 Topics: Acute Disease; Adolescent; Adult; Agranulocytosis; Antilymphocyte Serum; Bone Marrow Transplantation	1970
Aplastic anaemia. 3. Aplastic anaemia and infectious hepatitis. Acta medica Scandinavica, 1972, Volume: 192, Issue:4 Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Chloramphenicol; Female; Hepatitis A; Humans; Male; Oxyph	1972
[Virushepatitis and panmyelophthisis]. Zeitschrift fur arztliche Fortbildung, 1971, Nov-01, Volume: 65, Issue:21 Topics: Adolescent; Adult; Age Factors; Aged; Anemia, Myelophthisic; Animals; Autoimmune Diseases; Biopsy; B	1971
[Virus hepatitis and panmyelophthisis]. Padiatrie und Grenzgebiete, 1971, Volume: 10, Issue:3 Topics: Anemia, Aplastic; Autopsy; Child; Chloramphenicol; Female; Hepatitis A; Humans; Infant	1971
[Bone marrow aplasia in connection with epidemic hepatitis. 2 cases]. Ugeskrift for laeger, 1969, Nov-06, Volume: 131, Issue:45 Topics: Adult; Anemia, Aplastic; Blood Transfusion; Chloramphenicol; Female; Hepatitis A; Humans; Male; Pred	1969
[Bone marrow lesions following viral hepatitis]. Die Medizinische Welt, 1970, Jul-25, Volume: 30 Topics: Aged; Agranulocytosis; Autoimmune Diseases; Bone Marrow Diseases; Chloramphenicol; Hepatitis A; Huma	1970
[Panmyelopathy after viral hepatitis. Comment to H. Wallnöfer, K. Tauber: Med. Klin. 65 (1970), 159]. Medizinische Klinik, 1970, Oct-16, Volume: 65, Issue:42 Topics: Aminopyrine; Asthma; Azathioprine; Bone Marrow Diseases; Chloramphenicol; Female; Hepatitis A; Human	1970
[Hepatitis and panmyelophthisis]. Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:4 Topics: Acute Disease; Ampicillin; Anemia, Aplastic; Blood Transfusion; Child; Child, Preschool; Chloramphen	1970
[Panmyelopathy following acute hepatitis]. Medizinische Klinik, 1968, May-10, Volume: 63, Issue:19 Topics: Acute Disease; Adult; Blood Transfusion; Bone Diseases; Bone Marrow Diseases; Bone Marrow Examinatio	1968
[Pancytopenia following viral hepatitis]. Medizinische Klinik, 1969, Jun-06, Volume: 64, Issue:23 Topics: Anemia, Aplastic; Anti-Bacterial Agents; Blood Transfusion; Bone Marrow Examination; Chloramphenicol	1969
[4 autopsy cases of severe hepatitis]. Iryo, 1966, Volume: 20, Issue:4 Topics: Abortion, Legal; Adult; Chemical and Drug Induced Liver Injury; Chloramphenicol; Female; Hepatitis;	1966