chloramphenicol and Endophthalmitis studies

Endophthalmitis: Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection.

Research Excerpts

Excerpt	Relevance	Reference
"The main aim of the study was to assess whether omitting prophylactic postoperative topical antibiotics (chloramphenicol) influenced the risk of developing endophthalmitis after cataract surgery."	7.79	Endophthalmitis following cataract surgery: the role of prophylactic postoperative chloramphenicol eye drops. ( Drolsum, L; Råen, M; Sandvik, GF, 2013)
"In 520 consecutive cataract extractions, 1 gm chloramphenicol has been given intravenously immediately before entering the anterior chamber of the eye with no known resultant blood dyscrasias and no bacterial endophthalmitis."	7.66	Intravenous chloramphenicol to prevent postoperative endophthalmitis in cataract surgery--520 consecutive cases. ( Snyder, HP, 1978)
"Nonconcurrent analysis of 45,954 cataract operations performed by a single surgeon indicates that periocular injection of penicillin combined with multiple preoperative applications of topical chloramphenicol-sulphadimidine reduced the incidence of postoperative endophthalmitis by 72%."	5.04	Antibiotic prophylaxis of postoperative endophthalmitis. ( Christy, NE; Sommer, A, 1979)
"The main aim of the study was to assess whether omitting prophylactic postoperative topical antibiotics (chloramphenicol) influenced the risk of developing endophthalmitis after cataract surgery."	3.79	Endophthalmitis following cataract surgery: the role of prophylactic postoperative chloramphenicol eye drops. ( Drolsum, L; Råen, M; Sandvik, GF, 2013)
"In 520 consecutive cataract extractions, 1 gm chloramphenicol has been given intravenously immediately before entering the anterior chamber of the eye with no known resultant blood dyscrasias and no bacterial endophthalmitis."	3.66	Intravenous chloramphenicol to prevent postoperative endophthalmitis in cataract surgery--520 consecutive cases. ( Snyder, HP, 1978)
"Endophthalmitis is but one of the apparently increasing number of unsuual complications that may be observed as a result of H influenzae type b bacteremia."	1.26	Endophthalmitis associated with Haemophilus influenzae type b bacteremia and meningitis. ( Baker, CJ; Sastry, RV, 1979)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (50.00)	18.7374
1990's	4 (14.29)	18.2507
2000's	4 (14.29)	29.6817
2010's	3 (10.71)	24.3611
2020's	3 (10.71)	2.80

Authors	Studies
Guo, B	1
Au, B	1
Allen, P	1
Van Heerden, A	1
Trovato Battagliola, E	1
Riveros Cabral, RJ	1
Manco, G	1
Puggioni, G	1
Brancato, C	1
Mangiantini, P	1
Testa, F	1
Malvasi, M	1
Raponi, G	1
Turchetti, P	1
Pacella, F	1
Pacella, E	1
Grandi, G	1
Bianco, G	1
Boattini, M	1
Scalabrin, S	1
Iannaccone, M	1
Fea, A	1
Cavallo, R	1
Costa, C	1
Dadia, SD	1
Modi, RR	1
Shirwadkar, S	1
Potdar, NA	1
Shinde, CA	1
Nair, AG	1
Akkach, S	1
Kam, J	1
Meusemann, R	1
Råen, M	1
Sandvik, GF	1
Drolsum, L	1
SAUBERMANN, G	1
THEODORE, FH	1
BERAN, V	1
PINCUS, J	1
DEITER, P	1
SEARS, ML	1
Seppälä, H	1
Al-Juhaish, M	1
Järvinen, H	1
Laitinen, R	1
Huovinen, P	1
Liu, DT	1
Hui, M	1
Lam, DS	1
Chan, WM	1
Bloom, C	1
Thomson, EC	1
Main, J	1
Wong, JG	1
Bank, A	1
Taylor, JR	1
Cibis, GW	1
Hamtil, LW	1
Kirkness, CM	1
Seal, DV	2
Hay, J	1
Gerding, DN	1
Poley, BJ	1
Hall, WH	1
LeWin, DP	1
Clark, MD	1
Perry, LD	1
Skaggs, C	1
Snyder, HP	1
Sastry, RV	1
Baker, CJ	1
Christy, NE	1
Sommer, A	1
Nigrin, J	1
Tyrrell, DL	1
Jackson, FL	1
Ombres, SR	1
Morgan, RA	1
Pivetti-Pezzi, P	1
Accorinti, M	1
Liu, X	1
Heathcote, JG	1
McCartney, AC	1
Rice, NS	1
Peacock, J	1
Jensen, AD	1
Naidoff, MA	1
Koziol, J	1
Peyman, G	1
Bigger, JF	1
Meltzer, G	1
Mandell, A	1
Burde, RM	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
Intracameral Levofloxacin (0.5%) Versus Intracameral Cefuroxime (1mg/0.1ml) Effect on Corneal Endothelial Cell Count and Morphology in Uneventful Phacoemulsification[NCT04212078]			Phase 1/Phase 2	138 participants (Anticipated)	Interventional	2019-07-29	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Topical antibiotic prophylaxis before intravitreal injections: a pilot study. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023, Volume: 261, Issue:10 Topics: Adolescent; Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Chlor	2023
Antibiotic prophylaxis of postoperative endophthalmitis. Annals of ophthalmology, 1979, Volume: 11, Issue:8 Topics: Anti-Bacterial Agents; Cataract Extraction; Chloramphenicol; Drug Combinations; Drug Therapy, Combin	1979

Article	Year
Role of chloramphenicol eye drops for endophthalmitis prophylaxis following cataract surgery: Outcomes of institutional cessation. Clinical & experimental ophthalmology, 2021, Volume: 49, Issue:9 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract; Cataract Extraction; Chloramphenicol; Endop	2021
Bacterial etiology and antimicrobial resistance trends in ocular infections: A 30-year study, Turin area, Italy. European journal of ophthalmology, 2021, Volume: 31, Issue:2 Topics: Anti-Bacterial Agents; Bacteria; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Endophthalmi	2021
Post-cataract surgery endophthalmitis: The role of prophylactic antibiotic eye drops. Clinical & experimental ophthalmology, 2019, Volume: 47, Issue:4 Topics: Administration, Ophthalmic; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Chlo	2019
Endophthalmitis following cataract surgery: the role of prophylactic postoperative chloramphenicol eye drops. Acta ophthalmologica, 2013, Volume: 91, Issue:2 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chloramphenicol; Dexamethaso	2013
[EXOGENOUS INFECTIONS OF THE EYE]. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 1964, Volume: 147 Topics: Anthelmintics; Anti-Bacterial Agents; Antifungal Agents; Aqueous Humor; Chloramphenicol; Chlortetrac	1964
TREATMENT OF BACTERIAL ENDOPHTHALMITIS FOLLOWING CATARACT EXTRACTION. Eye, ear, nose & throat monthly, 1964, Volume: 43 Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Cataract Extraction; Ch	1964
[EFFECT OF MODERN TREATMENT OF PERFORATING INJURIES ON THE TERMINAL FUNCTION OF THE EYE]. Ceskoslovenska oftalmologie, 1964, Volume: 20 Topics: Chloramphenicol; Endophthalmitis; Eye Injuries; Humans; Ophthalmia, Sympathetic; Vision, Ocular	1964
EXPERIENCES WITH FIVE CASES OF POSTOPERATIVE ENDOPHTHALMITIS. American journal of ophthalmology, 1965, Volume: 59 Topics: Adrenal Cortex Hormones; Cataract Extraction; Chloramphenicol; Drug Therapy; Endophthalmitis; Geriat	1965
Effect of prophylactic antibiotics on antimicrobial resistance of viridans streptococci in the normal flora of cataract surgery patients. Journal of cataract and refractive surgery, 2004, Volume: 30, Issue:2 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Chloram	2004
Effect of prophylactic antibiotics on antimicrobial resistance of viridans streptococci in the normal flora of cataract surgery patients. Journal of cataract and refractive surgery, 2005, Volume: 31, Issue:4 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cataract Extraction; Chloramphenicol; Chloramphenicol	2005
An elderly lady with sudden blindness and a sore foot. The Journal of infection, 2006, Volume: 52, Issue:2 Topics: Administration, Topical; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Blindness; Ceftriaxon	2006
Surgical removal of intraocular antibiotic ointment after routine cataract phacoemulsification. Journal of cataract and refractive surgery, 2006, Volume: 32, Issue:5 Topics: Aged; Anterior Chamber; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chloramphenicol; Endophthalmi	2006
Endophthalmitis complicating Haemophilus influenzae type B meningitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1980, Volume: 98, Issue:2 Topics: Chloramphenicol; Dexamethasone; Endophthalmitis; Eye; Female; Haemophilus influenzae; Humans; Infant	1980
Topical chloramphenicol: use or abuse? Eye (London, England), 1995, Volume: 9 ( Pt 4) Topics: Administration, Topical; Anti-Bacterial Agents; Blepharitis; Bone Marrow; Chloramphenicol; Conjuncti	1995
Treatment of Pseudomonas endophthalmitis associated with prosthetic intraocular lens implantation. American journal of ophthalmology, 1979, Volume: 88, Issue:5 Topics: Anti-Bacterial Agents; Carbenicillin; Cephalothin; Chloramphenicol; Endophthalmitis; Gentamicins; Hu	1979
Preoperative topical antibiotics and lash trimming in cataract surgery. Ophthalmic surgery, 1977, Volume: 8, Issue:5 Topics: Administration, Topical; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Cataract Extraction;	1977
Intravenous chloramphenicol to prevent postoperative endophthalmitis in cataract surgery--520 consecutive cases. Annals of ophthalmology, 1978, Volume: 10, Issue:8 Topics: Agranulocytosis; Cataract Extraction; Chloramphenicol; Drug Evaluation; Endophthalmitis; Humans; Inf	1978
Endophthalmitis associated with Haemophilus influenzae type b bacteremia and meningitis. American journal of diseases of children (1960), 1979, Volume: 133, Issue:6 Topics: Administration, Topical; Ampicillin; Atropine; Chloramphenicol; Cyclopentolate; Dexamethasone; Endop	1979
Listeria monocytogenes endophthalmitis in an immune-suppressed host. Canadian Medical Association journal, 1977, Jun-18, Volume: 116, Issue:12 Topics: Aged; Chloramphenicol; Endophthalmitis; Humans; Immunity, Cellular; Listeria monocytogenes; Listerio	1977
Propionibacterium endophthalmitis. Ophthalmology, 1992, Volume: 99, Issue:12 Topics: Administration, Oral; Cataract Extraction; Chloramphenicol; Endophthalmitis; Eye Infections, Bacteri	1992
[Culture of anaerobic bacteria and antibiotic sensitivity test in ocular infectious diseases]. [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1991, Volume: 27, Issue:2 Topics: Adult; Bacteria, Anaerobic; Cephaloridine; Chloramphenicol; Conjunctivitis, Bacterial; Dacryocystiti	1991
Endophthalmitis caused by exogenous nocardial infection in a patient with Sjögren's syndrome. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1990, Volume: 25, Issue:1 Topics: Chloramphenicol; Corneal Diseases; Endophthalmitis; Eye Enucleation; Eye Infections, Bacterial; Fema	1990
Bilateral meningococcal endophthalmitis. Archives of ophthalmology (Chicago, Ill. : 1960), 1973, Volume: 90, Issue:5 Topics: Atropine; Borates; Child; Chloramphenicol; Conjunctiva; Cornea; Endophthalmitis; Exudates and Transu	1973
Intraocular chloramphenicol and bacterial endophthalmitis. Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1974, Volume: 9, Issue:3 Topics: Animals; Aqueous Humor; Chloramphenicol; Endophthalmitis; Escherichia coli Infections; Injections; M	1974
Serratia marcescens endophthalmitis. American journal of ophthalmology, 1971, Volume: 72, Issue:6 Topics: Aged; Anterior Chamber; Bacitracin; Cataract Extraction; Cephalothin; Chloramphenicol; Conjunctiva;	1971

chloramphenicol and Endophthalmitis

Research Excerpts

Research

Studies (28)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies