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chloramphenicol and Aging

chloramphenicol has been researched along with Aging in 21 studies

Amphenicol: Chloramphenicol and its derivatives.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Diminished renal function and activity of some hepatic enzymes alter the half-lives of various drugs, making extrapolation from adult dosage impossible."2.36Antimicrobial therapy and the neonate. ( Yaffe, SJ, 1981)
"Necropsy revealed brain abscesses with Escherichia Coli in pure culture."1.29Meningoencephalitis and brain abscessation due to Escherichia coli in a 2 week old alpaca cria. ( Dvir, I; Harmelin, A; Tsur, I; Yanai, J, 1996)
"Chloramphenicol was administered by the intravenous, intramuscular or oral route and dosage ranged between 12 and 210 mg/kg/day."1.27The pharmacokinetics of chloramphenicol in the neonate and young infant. ( de Louvois, J; Hurley, R; Mulhall, A, 1983)
"Rats treated with chloramphenicol from days 7 to 21 of intrauterine life (50 milligrams per kilogram per day, injected subcutaneously into the mothers) or in the first 3 days of extrauterine life (50 to 100 milligrams per kilogram per day) were trained for avoidance conditioning when 60 days old."1.26Chloramphenicol administration during brain development: impairment of avoidance learning in adulthood. ( Bertolini, A; Poggioli, R, 1981)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199017 (80.95)18.7374
1990's4 (19.05)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
MARTIN, WJ1
MCHENRY, MC1
Holden, JT1
Utech, NM1
Prokopczyk, L1
Jahn-Andrychowska, W1
Wańkowicz, B1
Kamińska, E1
Mulhall, A1
de Louvois, J1
Hurley, R1
Rajchgot, P1
Prober, CG1
Soldin, S1
Golas, C1
Good, F1
Harding, E1
MacLeod, S1
Yamakawa, T1
Itoh, S1
Onishi, S1
Isobe, K1
Hosoe, A1
Nishimura, Y1
Heimpel, H1
Heit, W1
Yaffe, SJ1
Guentzel, MN1
Herrera, C1
Posner, JD1
Bertolini, A1
Poggioli, R1
Ashour, B2
Tribe, M2
Whittaker, P2
Danks, S1
Tsur, I1
Harmelin, A1
Dvir, I1
Yanai, J1
Young, WS1
Lietman, PS1
Eberhart, D1
Fitzgerald, K1
Parkinson, A1
Adamson, PJ1
Wilson, WD1
Baggot, JD1
Hietala, SK1
Mihalyi, JE1
Abramson, JS1
Givner, LB1
Peak, MJ1
Peak, JG1
Ting, IP1
Gorodischer, R1
Moses, SW1
Bashan, N1
Subrahmanyan, TP1

Reviews

2 reviews available for chloramphenicol and Aging

ArticleYear
Drug-induced aplastic anaemia: clinical aspects.
    Clinics in haematology, 1980, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Aging; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Colchici

1980
Antimicrobial therapy and the neonate.
    Obstetrics and gynecology, 1981, Volume: 58, Issue:5 Suppl

    Topics: Absorption; Aging; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Biological Availabi

1981

Other Studies

19 other studies available for chloramphenicol and Aging

ArticleYear
BACTEREMIA DUE TO GRAM-NEGATIVE BACILLI. RESUME OF EXPERIENCES IN 303 CASES.
    The Journal-lancet, 1964, Volume: 84

    Topics: Aging; Angiotensins; Bacteremia; Bacteroides; Chloramphenicol; Colistin; Drug Therapy; Enterobacter

1964
Effect of biotin, pantothenic acid and nicotinic acid deficiencies on amino acid transport in Lactobacillus plantarum.
    Biochimica et biophysica acta, 1967, Jul-03, Volume: 135, Issue:3

    Topics: Acetates; Aging; Avitaminosis; Biological Transport; Biotin; Carbon Isotopes; Cell Membrane Permeabi

1967
[Chloramphenicol metabolism in the tissues of newborn and adult rabbits].
    Problemy medycyny wieku rozwojowego, 1984, Volume: 13

    Topics: Aging; Animals; Animals, Newborn; Biotransformation; Chloramphenicol; Female; In Vitro Techniques; I

1984
The pharmacokinetics of chloramphenicol in the neonate and young infant.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:6

    Topics: Administration, Oral; Aging; Chloramphenicol; Drug Interactions; Female; Humans; Infant; Infant, New

1983
Chloramphenicol in the newborn infant.
    Progress in clinical and biological research, 1983, Volume: 135

    Topics: Aging; Chloramphenicol; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kinet

1983
Developmental changes in hepatic esterase activity towards chloramphenicol succinate and its Michaelis-Menten constant of liver, kidney and lung in human.
    Developmental pharmacology and therapeutics, 1984, Volume: 7, Issue:3

    Topics: Adult; Aging; Child, Preschool; Chloramphenicol; Esterases; Female; Fetus; Gestational Age; Humans;

1984
Effects of compromising agents on candidosis in mice with persistent infections initiated in infancy.
    Infection and immunity, 1982, Volume: 35, Issue:1

    Topics: Aging; Animals; Candida albicans; Candidiasis; Chloramphenicol; Cortisone; Cyclophosphamide; Digesti

1982
Particular problems of antibiotic use in the elderly.
    Geriatrics, 1982, Volume: 37, Issue:8

    Topics: Aged; Aging; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Antitubercular Age

1982
Chloramphenicol administration during brain development: impairment of avoidance learning in adulthood.
    Science (New York, N.Y.), 1981, Jul-10, Volume: 213, Issue:4504

    Topics: Aging; Animals; Avoidance Learning; Brain; Chloramphenicol; Female; Male; Maternal-Fetal Exchange; P

1981
The effect of chloramphenicol, ethidium bromide and cycloheximide on mortality and mitochondrial protein synthesis of adult blowflies.
    Journal of cell science, 1980, Volume: 41

    Topics: Aging; Animals; Chloramphenicol; Cycloheximide; Diptera; Dose-Response Relationship, Drug; Ethidium;

1980
Biochemical and ultrastructural studies on flight muscle mitochondria from the blowfly Calliphora erythrocephala following treatment by chloramphenicol and ethidium bromide.
    Journal of cell science, 1980, Volume: 41

    Topics: Aging; Animals; Chloramphenicol; Cytochromes; Diptera; Dose-Response Relationship, Drug; Ethidium; M

1980
Meningoencephalitis and brain abscessation due to Escherichia coli in a 2 week old alpaca cria.
    Australian veterinary journal, 1996, Volume: 74, Issue:6

    Topics: Aging; Animals; Anorexia; Anti-Bacterial Agents; Anti-Inflammatory Agents; Brain; Brain Abscess; Cam

1996
Chloramphenicol glucuronyl transferase: assay, ontogeny and inducibility.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 204, Issue:1

    Topics: Aging; Animals; Chloramphenicol; Enzyme Induction; Female; Fetus; Glucuronosyltransferase; In Vitro

1978
Evidence for the involvement of a distinct form of cytochrome P450 3A in the oxidation of digitoxin by rat liver microsomes.
    Journal of biochemical toxicology, 1992,Spring, Volume: 7, Issue:1

    Topics: Aging; Analysis of Variance; Animals; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrom

1992
Influence of age on the disposition kinetics of chloramphenicol in equine neonates.
    American journal of veterinary research, 1991, Volume: 52, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Chloramphenicol; Female; Horses; Infusions, Intravenous; Labor, In

1991
Should tetracycline be contraindicated for therapy of presumed Rocky Mountain spotted fever in children less than 9 years of age?
    Pediatrics, 1990, Volume: 86, Issue:1

    Topics: Aging; Child; Chloramphenicol; Humans; Rocky Mountain Spotted Fever; Tetracycline

1990
Function and regulation of NADP-specific malate dehydrogenase in Euglena gracilis Z.
    Biochimica et biophysica acta, 1973, Feb-15, Volume: 293, Issue:2

    Topics: Aging; Animals; Carbon Dioxide; Chloramphenicol; Chlorophyll; Chromatography, DEAE-Cellulose; Chroma

1973
Pharmacological modification of glutathione and NADP+ reduction.
    Advances in experimental medicine and biology, 1972, Volume: 27

    Topics: Adult; Aging; Aspirin; Binding, Competitive; Chloramphenicol; Erythrocytes; Glucosephosphate Dehydro

1972
Effect of neonatal thymectomy and thiotepa on the susceptibility of mice to the lethal effects of poxviruses.
    The Australian journal of experimental biology and medical science, 1968, Volume: 46, Issue:3

    Topics: Aging; Animals; Antibody Formation; Antigen-Antibody Reactions; Chloramphenicol; Ectromelia virus; G

1968