Compounds > chloramphenicol
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chloramphenicol and Acute Liver Injury, Drug-Induced

chloramphenicol has been researched along with Acute Liver Injury, Drug-Induced in 44 studies

Amphenicol: Chloramphenicol and its derivatives.

Research Excerpts

ExcerptRelevanceReference
" However, their potential for adverse effects, both toxic and allergic, must always be kept in mind."2.36Common adverse effects of antibacterial agents on major organ systems. ( Calderwood, SB; Moellering, RC, 1980)
"The patient developed severe toxic hepatitis as a result of this incorrect treatment."1.27[A case of severe methacycline damage to the liver and bone marrow]. ( Chernev, K; Iordanova, E; Khadzhieva, Zh, 1987)
" The consequences of liver damage for withdrawal times and dosage schedules are discussed."1.27The pharmacokinetic behaviour of chloramphenicol in liver-damaged mini-pigs. ( Kroker, R, 1985)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-199036 (81.82)18.7374
1990's1 (2.27)18.2507
2000's1 (2.27)29.6817
2010's6 (13.64)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fourches, D1
Barnes, JC1
Day, NC1
Bradley, P1
Reed, JZ1
Tropsha, A1
Morgan, RE2
Trauner, M1
van Staden, CJ2
Lee, PH1
Ramachandran, B1
Eschenberg, M1
Afshari, CA2
Qualls, CW1
Lightfoot-Dunn, R1
Hamadeh, HK2
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W2
Warner, DJ1
Chen, H1
Cantin, LD1
Kenna, JG1
Stahl, S1
Walker, CL1
Noeske, T1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Chen, M1
Suzuki, A1
Thakkar, S1
Yu, K1
Hu, C1
Doshi, B1
Sarkar, S1
TERZANI, A1
DOWLING, HF2
LEPPER, MH2
LEHNER, T1
LOCKEY, SD1
FUKAYA, K1
TOMORI, G1
GARROD, LP1
YESNER, R1
KUNKEL, P1
ZIMMERMAN, HJ1
CARROLL, G1
CALDWELL, ER1
SPIES, HW1
WOLFE, CK1
Needham, WP1
Shuster, L1
Kanel, GC1
Thompson, ML1
Calderwood, SB1
Moellering, RC1
Feder, HM1
Casale, TB1
Macher, AM1
Fauci, AS1
Shibata, A2
Fukuda, M2
Fracasso, ME1
Leone, R1
Gralla, EJ1
Horsmans, Y1
Larrey, D1
Pessayre, D1
Benhamou, JP1
Khadzhieva, Zh1
Chernev, K1
Iordanova, E1
Kunii, O1
Kroker, R1
Dölle, W1
Furuyama, M1
Matsuda, I1
Weinstein, L1
Weinstein, AJ1
Hirasawa, K1
VanOmmen, RA1
Westerholm, B1
Fossati, C2
LaMont, JT1
Ito, M1
Fukuiya, Y1
Hodgkinson, R1
Kanetaka, T2
Oda, T1
Renis, M1
Giovine, A1
Rizzi, MM1
Bertolino, A1
Pershin, GN1
Skorodumova, IV1
Juchum, W1
Suzuki, H1

Reviews

10 reviews available for chloramphenicol and Acute Liver Injury, Drug-Induced

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr

2016
Common adverse effects of antibacterial agents on major organ systems.
    The Surgical clinics of North America, 1980, Volume: 60, Issue:1

    Topics: Adult; Anaphylaxis; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Child, Preschool;

1980
[Hepatotoxicity of antimicrobial agents. I: Antibacterial antibiotics].
    Gastroenterologie clinique et biologique, 1990, Volume: 14, Issue:12

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Chloramphenicol; Humans; Lactams; Mac

1990
[Toxic hepatitis induced by antibiotics].
    Nihon rinsho. Japanese journal of clinical medicine, 1985, Volume: 43, Issue:6

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Chloramphenicol; Erythromycin Estolat

1985
The pathophysiology and pathoanatomy of reactions to antimicrobial agents.
    Advances in internal medicine, 1974, Volume: 19

    Topics: Aminosalicylic Acids; Anti-Infective Agents; Bone Marrow Diseases; Chemical and Drug Induced Liver I

1974
[Liver damage due to drugs. I].
    La Clinica terapeutica, 1974, Jan-15, Volume: 68, Issue:1

    Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Re

1974
Postoperative juandice.
    The Surgical clinics of North America, 1974, Volume: 54, Issue:3

    Topics: Aminosalicylic Acids; Anemia, Hemolytic; Bile Ducts; Bilirubin; Chemical and Drug Induced Liver Inju

1974
[Liver damage due to drugs. II].
    La Clinica terapeutica, 1974, Jan-31, Volume: 68, Issue:2

    Topics: Ampicillin; Antitubercular Agents; Asparaginase; Chemical and Drug Induced Liver Injury; Chloramphen

1974
[Hepatitis-aplastic anemia syndrome (after the administration of chloramphenicol) (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1974, Volume: 15, Issue:9

    Topics: Adult; Aged; Anemia, Aplastic; Autopsy; Bone Marrow; Chemical and Drug Induced Liver Injury; Chloram

1974
[Morphology of the side effects of drugs in humans].
    Arkhiv patologii, 1969, Volume: 31, Issue:9

    Topics: Adrenal Cortex Hormones; Agranulocytosis; Alopecia; Analgesics; Anti-Bacterial Agents; Breast; Chemi

1969

Other Studies

34 other studies available for chloramphenicol and Acute Liver Injury, Drug-Induced

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2010
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Topical administration of chloramphenicol can induce acute hepatitis.
    BMJ (Clinical research ed.), 2009, Jun-12, Volume: 338

    Topics: Acute Disease; Administration, Topical; Adult; Anti-Bacterial Agents; Chemical and Drug Induced Live

2009
[DAMAGE FROM THERAPY].
    La Clinica terapeutica, 1963, Oct-15, Volume: 27

    Topics: Adrenal Cortex Hormones; Anemia; Anemia, Aplastic; Anticoagulants; Antipyrine; Blood Group Incompati

1963
HEPATIC REACTIONS TO TETRACYCLINE.
    JAMA, 1964, Apr-20, Volume: 188

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Child; Chloramphenicol; Chlortetracyc

1964
SYSTEMIC CANDIDIASIS AND RENAL INVOLVEMENT.
    Lancet (London, England), 1964, Jun-27, Volume: 2, Issue:7348

    Topics: Anti-Bacterial Agents; Candidiasis; Chemical and Drug Induced Liver Injury; Chloramphenicol; Diagnos

1964
ADVERSE REACTIONS TO DRUGS.
    Pennsylvania medical journal (1928), 1964, Volume: 67

    Topics: Anaphylaxis; Anti-Bacterial Agents; Aspirin; Chemical and Drug Induced Liver Injury; Chloramphenicol

1964
[CASE OF HYPERSENSITIVE HEPATITIS DUE TO PROPIONYL ERYTHROMYCIN LAURYL SULFATE].
    Naika. Internal medicine, 1964, Volume: 14

    Topics: Adolescent; Chemical and Drug Induced Liver Injury; Chloramphenicol; Drug Therapy; Erythromycin; Hep

1964
THE TOXICITY OF ANTIBIOTICS.
    The Medical journal of Australia, 1964, Dec-12, Volume: 2

    Topics: Anemia; Anemia, Aplastic; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacitracin; Chemical a

1964
Preliminary observations on the effect of aureomycin, terramycin, tibione, combined tibione and streptomycin, and chloromycetin on the morphology of the liver in man.
    The Yale journal of biology and medicine, 1951, Volume: 23, Issue:4

    Topics: Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Chloramphenicol; Chlortetracycline; L

1951
Effect of large doses of aureomycin, terramycin, and chloramphenicol on livers of mice and dogs.
    A.M.A. archives of internal medicine, 1951, Volume: 88, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Chlortetracycline; Dogs; Liver; Mi

1951
Liver damage from narcotics in mice.
    Toxicology and applied pharmacology, 1981, Volume: 58, Issue:2

    Topics: Animals; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cytoc

1981
Do we really need to monitor liver function in patients receiving chloramphenicol?
    The Journal of pediatrics, 1983, Volume: 103, Issue:2

    Topics: Chemical and Drug Induced Liver Injury; Child; Chloramphenicol; Humans; Liver Function Tests

1983
Complete hematologic and hepatic recovery in a patient with chloramphenicol hepatitis-pancytopenia syndrome.
    The Journal of pediatrics, 1982, Volume: 101, Issue:6

    Topics: Adolescent; Bacterial Infections; Chemical and Drug Induced Liver Injury; Chloramphenicol; Chromobac

1982
[Chloramphenicol-hepatitis-aplastic anemia syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 1977,Spring, Volume: 35 Suppl 1

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Chemical and Drug Induced Liver Injury; Child; Child, Pre

1977
[Metabolism of chloramphenicol in the isolated and perfused liver of rats poisoned with carbon tetrachloride and fed a steatogenic diet].
    La Clinica terapeutica, 1977, Jan-15, Volume: 80, Issue:1

    Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chloramphenicol; Fa

1977
[Chloramphenicol, liver and hemopoiesis (author's transl)].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1977, Volume: 18, Issue:6

    Topics: Adolescent; Adult; Aged; Animals; Chemical and Drug Induced Liver Injury; Child; Child, Preschool; C

1977
Adverse drug reactions.
    The Veterinary clinics of North America, 1975, Volume: 5, Issue:4

    Topics: Abnormalities, Drug-Induced; Acute Kidney Injury; Agranulocytosis; Anemia, Aplastic; Anemia, Hemolyt

1975
[A case of severe methacycline damage to the liver and bone marrow].
    Vutreshni bolesti, 1987, Volume: 26, Issue:6

    Topics: Acute Disease; Bone Marrow; Bronchopneumonia; Chemical and Drug Induced Liver Injury; Chloramphenico

1987
The pharmacokinetic behaviour of chloramphenicol in liver-damaged mini-pigs.
    Journal of veterinary pharmacology and therapeutics, 1985, Volume: 8, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Female; Half-Life; Liver Diseases;

1985
[Herpes simplex hepatitis in the adult].
    Der Internist, 1972, Volume: 13, Issue:11

    Topics: Adrenal Cortex Hormones; Adult; Antigens, Viral; Chemical and Drug Induced Liver Injury; Chloramphen

1972
Chloramphenicol and jaundice in a baby.
    Lancet (London, England), 1967, Aug-12, Volume: 2, Issue:7511

    Topics: Chemical and Drug Induced Liver Injury; Chloramphenicol; Humans; Infant; Injections, Intramuscular;

1967
[Studies on renin-angiotensin system. I. Angiotensinase activities in hepatic disorders].
    Japanese circulation journal, 1968, Volume: 32, Issue:3

    Topics: Adult; Angiotensin II; Animals; Bile Duct Neoplasms; Biliary Tract Diseases; Blood Pressure; Carbon

1968
Untoward effects of antimicrobial agents on major organ systems.
    The Medical clinics of North America, 1974, Volume: 58, Issue:3

    Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia;

1974
Adverse reactions from chemotherapeutic agents as seen in a national monitoring centre.
    International journal of clinical pharmacology, therapy and toxicology, 1974, Volume: 9, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Chloramphenicol; Drug Hypersensitivity; Drug-Related Side Ef

1974
The chloramphenicol--hepatitis--aplastic anaemia syndrome.
    The Medical journal of Australia, 1973, May-12, Volume: 1, Issue:19

    Topics: Adult; Anemia, Aplastic; Blood Cell Count; Chemical and Drug Induced Liver Injury; Child; Child, Pre

1973
Toxic liver injuries.
    Acta pathologica japonica, 1973, Volume: 23, Issue:3

    Topics: Anti-Bacterial Agents; Antipyrine; Antitubercular Agents; Biopsy; Carbon Tetrachloride Poisoning; Ce

1973
[Ethanol-induced changes in protein synthesis of mitochondria and microsomes of rat brain and liver].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Sep-15, Volume: 49, Issue:17

    Topics: Alcoholic Intoxication; Animals; Brain; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cyc

1973
[Chloramphenicol panmyelopathy in a child].
    Wiener medizinische Wochenschrift (1946), 1970, Jul-25, Volume: 120, Issue:30

    Topics: Anabolic Agents; Blood Cell Count; Blood Transfusion; Bone Marrow; Bone Marrow Diseases; Bone Marrow

1970
[Liver injury caused by chemotherapeutics].
    Saishin igaku. Modern medicine, 1969, Volume: 24, Issue:9

    Topics: Adult; Anti-Bacterial Agents; Cephalothin; Chemical and Drug Induced Liver Injury; Chloramphenicol;

1969
[4 autopsy cases of severe hepatitis].
    Iryo, 1966, Volume: 20, Issue:4

    Topics: Abortion, Legal; Adult; Chemical and Drug Induced Liver Injury; Chloramphenicol; Female; Hepatitis;

1966