chlorambucil has been researched along with Wilms Tumor in 6 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Wilms Tumor: A malignant kidney tumor, caused by the uncontrolled multiplication of renal stem (blastemal), stromal (STROMAL CELLS), and epithelial (EPITHELIAL CELLS) elements. However, not all three are present in every case. Several genes or chromosomal areas have been associated with Wilms tumor which is usually found in childhood as a firm lump in a child's side or ABDOMEN.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SMITH, JC | 1 |
| BOLANDE, RP | 1 |
| Valdez, VA | 1 |
| Planas, AT | 1 |
| Lopez, VF | 1 |
| Goldberg, M | 1 |
| Herrera, NE | 1 |
| Wedemeyer, PP | 1 |
| White, JG | 1 |
| Nesbit, ME | 1 |
| Aust, JB | 1 |
| Leonard, AS | 1 |
| D'Angio, GJ | 1 |
| Krivit, W | 1 |
| Armstrong, JG | 1 |
| Furnari, S | 1 |
| Pavone-Macaluso, M | 1 |
| Veroux, G | 1 |
| Mattea, E | 1 |
| Klener, P | 1 |
1 trial available for chlorambucil and Wilms Tumor
| Article | Year |
|---|---|
Vinca alkaloids. Experimental and clinical trials.
Topics: Animals; Cell Movement; Chlorambucil; Choriocarcinoma; Female; Hematopoiesis; Hematopoietic Stem Cel | 1974 |
5 other studies available for chlorambucil and Wilms Tumor
| Article | Year |
|---|---|
RADIATION AND DRUG INDUCED HYALINIZATION OF THE STOMACH.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Drug Therapy; Ganglioneuroma; Gastroin | 1965 |
Adenosarcoma of uterus and ovary: a clinicopathologic study of two cases.
Topics: Adult; Chlorambucil; Cyclophosphamide; Cytoplasm; Female; Humans; Middle Aged; Neoplasm Metastasis; | 1979 |
Resection of metastases in Wilms' tumor: a report of three cases cured of pulmonary and hepatic metastases.
Topics: Child, Preschool; Chlorambucil; Cobalt Isotopes; Dactinomycin; Female; Humans; Infant; Liver Neoplas | 1968 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |