chlorambucil has been researched along with Waldenstrom Macroglobulinemia in 132 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Waldenstrom Macroglobulinemia: A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Few recurrent chromosomal abnormalities have been reported, and their prognostic value is not known." | 2.78 | Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia. ( Andrieux, J; Baranger, L; Barin, C; Bilhou-Nabera, C; Blons, H; Callet-Bauchu, E; Chapiro, E; Chevret, S; Chiesa, J; Daudignon, A; Eclache, V; Gachard, N; Grelier, A; Henry, C; Lambert, J; Leblondon, V; Lejeune, J; Luquet, I; Merle-Beral, H; Mossafa, H; Mould, S; Mozziconacci, MJ; Mugneret, F; Nguyen-Khac, F; Owen, R; Penther, D; Struski, S; Terre, C; Veronese, L, 2013) |
| "Waldenström's macroglobulinemia is a rare malignant disorder of B lymphocytes." | 2.70 | IFN-alpha as induction and maintenance treatment of patients newly diagnosed with Waldenström's macroglobulinemia. ( Abraham-Majluf, S; Arenas-Osuna, J; Aviña-Zubieta, JA; García-Chávez, J; García-Ruiz Esparza, MA; Padilla-González, Y; Rosas-Cabral, A; Salazar-Exaire, D; Vadillo-Buenfil, M; Vela-Ojeda, J; Xolotl-Castillo, M, 2002) |
| "Chlorambucil is an effective agent and should be compared with purine analogues or rituxan (Rituximab) in a prospective study." | 2.69 | Waldenström's macroglobulinaemia: a prospective study comparing daily with intermittent oral chlorambucil. ( Gertz, MA; Greipp, PR; Kyle, RA; Lacy, MQ; Lust, JA; Therneau, TM; Witzig, TE, 2000) |
| "Waldenström's macroglobulinemia (WM) is a clinical syndrome with diverse prognoses, and not all patients require therapy at diagnosis." | 2.41 | Waldenström's macroglobulinemia. ( Barlogie, B; Desikan, KR; Dhodapkar, MV, 2000) |
| "A 67-year-old man with Waldenström's macroglobulinemia had a relapse of chronic idiopathic thrombocytopenic purpura (ITP), which had been refractory to corticosteroids, splenectomy, vinca alkaloids, and high-dose intravenous gamma-globulin therapy." | 2.39 | Role of plasmapheresis in thrombocytopenic purpura associated with Waldenström's macroglobulinemia. ( Moore, SB; Patel, TC; Pineda, AA; Witzig, TE, 1996) |
| "Sarcoidosis is seldom associated with Waldenström's macroglobulinaemia." | 2.38 | [Association of sarcoidosis and Waldenström's macroglobulinemia]. ( Boulitrop-Morvan, C; Camus, P; Collet, E; Dalac, S; Lambert, D, 1992) |
| "We report on a case of Waldenström's macroglobulinemia (WM) treated with splenic re-irradiation." | 1.38 | Splenic re-irradiation for waldenstrőm's macroglobulinemia. ( Han, W; Wei, Z; Yanxia, Y; Ying, X; Yuhua, J, 2012) |
| "Treatment with prednisone and chlorambucil was initiated, and the dog had a good response." | 1.37 | Waldenström's macroglobulinemia in a dog with a bleeding diathesis. ( Fournel-Fleury, C; Jaillardon, L, 2011) |
| "Cytogenetic analysis showed complex chromosomal abnormalities including 5q deletion, 12p deletion and monosomy 18." | 1.33 | Myelodysplastic syndrome with complex karyotypic abnormality in a patient with Waldenström's macroglobulinemia after sequential treatment with chlorambucil and fludarabine. ( Cho, HS; Chun, SH; Hyun, MS; Kim, KO; Kim, MK; Lee, KH; Shin, SJ, 2005) |
| "Waldenstrom's macroglobulinemia (WM) is a rare condition, accounting for approximately 2% of haematologic malignancies." | 1.33 | Waldenstrom's macroglobulinemia terminating in acute myeloid leukemia. ( Adil, SN; Khalid, S; Khurshid, M, 2006) |
| "A diagnosis of Waldenstrom's macroglobulinemia was made on the basis of these findings." | 1.33 | Bilateral orbital tumor formation and isolated facial palsy in Waldenstrom's macroglobulinemia. ( Chauhan, D; Das, S; Goyal, JL; Kumar, S; Sangit, V, 2005) |
| "Bartholomew's Hospital 40 untreated Waldenstrom's macroglobulinemia (WM) patients received either chlorambucil (n = 23); cyclophosphamide, vincristine, and prednisolone (CVP) (n = 5); fludarabine-based therapy (n = 5); or other combination chemotherapy (n = 7)." | 1.32 | Waldenstrom's macroglobulinemia: a retrospective analysis of 40 patients from 1972 to 2001. ( Amess, JA; Lister, TA; Matthews, J; Ngan, S; Norton, A; Rohatiner, AZ; Williams, A, 2003) |
| "Treatment with prednisolone and cyclophosphamide induced a rapid recovery from acute renal failure." | 1.31 | A case with acute renal failure complicated by Waldenström's macroglobulinemia and cryoglobulinemia. ( Fujigaki, Y; Hishida, A; Ikegaya, N; Sano, K; Suzuki, T; Yonemura, K, 2000) |
| "Bleeding tendency was seen in 17%, infections in 17%, hyperviscosity syndrome in 12%, and cardiac failure in 25% of the patients." | 1.31 | Waldenström's macroglobulinemia: clinical course and prognostic factors in 60 patients. Experience from a single hematology unit. ( Angelopoulou, MK; Boussiotis, V; Dimopoulou, MN; Fessas, P; Gribabis, A; Kittas, C; Konstantopoulos, K; Kontopidou, FN; Kyrtsonis, MC; Pangalis, GA; Siakantaris, P; Vaiopoulos, GA; Vassilakopoulos, TP, 2001) |
| "We describe a case of dry eye associated with Waldenström's macroglobulinemia that responded poorly to substitutive topical treatment but improved spectacularly in response to systemic chemotherapy." | 1.29 | Dry eye in Waldenström's macroglobulinemia. Improvement after systemic chemotherapy. ( Cordido, M; Fernández-Lago, C; Fernández-Vigo, J; López-Nieto, C, 1995) |
| "Schnitzler's syndrome has been described in 1972." | 1.29 | [Chronic urticaria-macroglobulinemia (Schnitzler syndrome): developing to IgM myeloma. Apropos of a case]. ( Brochot, P; Eschard, JP; Etienne, JC; Govindaraju, S; Morrone, A; Paternotte, L; Ringot, AC, 1993) |
| "Ataxia in macroglobulinemia has been attributed to cerebral infarction and blood hyperviscosity, but no previous case reports documented gradually progressive cerebellar signs without these concomitants and with regression on therapy." | 1.26 | Progressive and treatable cerebellar ataxia in macroglobulinemia. ( Moench, JC; Spencer, SS, 1980) |
| "Waldenstrom macroglobulinemia (WMG), a proliferation of malignant monoclonal IgM secreting plasmacytoid lymphocytes in lymph nodes, spleen, and marrow, usually pursues a chronic clinical course." | 1.26 | Pulmonary manifestations of Waldenstrom macroglobulinemia. ( Herion, JC; Rausch, PG, 1980) |
| "A case of Waldenström's macroglobulinemia in a 63-year-old man is presented." | 1.26 | [Waldenström's macroglobulinemia with immunocytoma of the lung]. ( Fontana, A; Fuchs, P; Sulser, H, 1977) |
| "This led to the discovery of a large malignant lymphoma of the nasopharynx." | 1.26 | Malignant lymphoma of thenasopharyns in waldenström's macroglobulinemia: report of a case with severe epistaxis. ( Napoli, VM; Nichols, CW; Wright, RE, 1977) |
| "The diagnosis of lymphocytic leukemia was based on the finding of a large number of mature lymphocytes in the blood and bone marrow." | 1.26 | Hyperviscosity syndrome associated with lymphocytic leukemia in three dogs. ( Hayes, A; Hurvitz, AI; MacEwen, EG, 1977) |
| "Treatment with chlorambucil resulted in normalization of the peripheral blood smear, but the malignant infiltration of the bone marrow continued and manifested itself by appearance of new osteolytic lesions, though some of the old lesions underwent recalcification after treatment." | 1.26 | Macroglobulinemia of Waldenström associated with severe osteolytic lesions. ( Krausz, Y; Zlotnick, A, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 94 (71.21) | 18.7374 |
| 1990's | 9 (6.82) | 18.2507 |
| 2000's | 18 (13.64) | 29.6817 |
| 2010's | 10 (7.58) | 24.3611 |
| 2020's | 1 (0.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chien, HC | 1 |
| Morreall, D | 1 |
| Patil, V | 1 |
| Rasmussen, KM | 1 |
| Yong, CM | 1 |
| Li, CY | 1 |
| Passey, DG | 1 |
| Burningham, Z | 1 |
| Sauer, BC | 1 |
| Halwani, AS | 1 |
| Leleu, X | 1 |
| Soumerai, J | 1 |
| Roccaro, A | 1 |
| Hatjiharissi, E | 1 |
| Hunter, ZR | 1 |
| Manning, R | 1 |
| Ciccarelli, BT | 1 |
| Sacco, A | 1 |
| Ioakimidis, L | 1 |
| Adamia, S | 1 |
| Moreau, AS | 1 |
| Patterson, CJ | 1 |
| Ghobrial, IM | 2 |
| Treon, SP | 1 |
| van Gaalen, FA | 1 |
| Zanin, DE | 1 |
| Brand, A | 1 |
| Harnalikar, M | 1 |
| Pande, S | 1 |
| Kharkar, V | 1 |
| Khopkar, U | 1 |
| Rourke, M | 1 |
| Anderson, KC | 1 |
| Gertz, MA | 2 |
| Peinert, S | 1 |
| Seymour, JF | 3 |
| van Gelder, M | 1 |
| van Marion, A | 1 |
| Goossens, V | 1 |
| Bommer, M | 1 |
| Leblond, V | 3 |
| Jaillardon, L | 1 |
| Fournel-Fleury, C | 1 |
| Pentsova, E | 1 |
| Rosenblum, M | 1 |
| Holodny, A | 1 |
| Palomba, ML | 1 |
| Omuro, A | 1 |
| Wei, Z | 1 |
| Yanxia, Y | 1 |
| Ying, X | 1 |
| Han, W | 1 |
| Yuhua, J | 1 |
| Nguyen-Khac, F | 2 |
| Lambert, J | 1 |
| Chapiro, E | 1 |
| Grelier, A | 1 |
| Mould, S | 1 |
| Barin, C | 1 |
| Daudignon, A | 1 |
| Gachard, N | 1 |
| Struski, S | 1 |
| Henry, C | 1 |
| Penther, D | 1 |
| Mossafa, H | 1 |
| Andrieux, J | 1 |
| Eclache, V | 1 |
| Bilhou-Nabera, C | 1 |
| Luquet, I | 1 |
| Terre, C | 1 |
| Baranger, L | 1 |
| Mugneret, F | 1 |
| Chiesa, J | 1 |
| Mozziconacci, MJ | 1 |
| Callet-Bauchu, E | 1 |
| Veronese, L | 1 |
| Blons, H | 1 |
| Owen, R | 1 |
| Lejeune, J | 2 |
| Chevret, S | 2 |
| Merle-Beral, H | 1 |
| Leblondon, V | 1 |
| Johnson, S | 1 |
| Copplestone, A | 1 |
| Rule, S | 1 |
| Tournilhac, O | 1 |
| Patmore, RD | 1 |
| Wright, D | 1 |
| Morel, P | 2 |
| Dilhuydy, MS | 1 |
| Willoughby, S | 1 |
| Dartigeas, C | 1 |
| Malphettes, M | 1 |
| Royer, B | 1 |
| Ewings, M | 1 |
| Pratt, G | 1 |
| Choquet, S | 1 |
| Owen, RG | 3 |
| Vela-Ojeda, J | 1 |
| García-Ruiz Esparza, MA | 1 |
| Padilla-González, Y | 1 |
| Rosas-Cabral, A | 1 |
| García-Chávez, J | 1 |
| Xolotl-Castillo, M | 1 |
| Salazar-Exaire, D | 1 |
| Arenas-Osuna, J | 1 |
| Aviña-Zubieta, JA | 1 |
| Vadillo-Buenfil, M | 1 |
| Abraham-Majluf, S | 1 |
| Zinzani, PL | 1 |
| Tani, M | 1 |
| Alinari, L | 1 |
| Stefoni, V | 1 |
| Baccarani, M | 1 |
| Ngan, S | 1 |
| Rohatiner, AZ | 1 |
| Matthews, J | 1 |
| Williams, A | 1 |
| Amess, JA | 1 |
| Norton, A | 1 |
| Lister, TA | 1 |
| BAYRD, ED | 2 |
| CLATANOFF, DV | 2 |
| MEYER, OO | 1 |
| KOK, D | 1 |
| FURGERSON, WB | 1 |
| BACHMAN, LB | 1 |
| O'TOOLE, WF | 1 |
| WALDENSTROEM, J | 1 |
| VERRASTRO, T | 1 |
| COELHO, E | 1 |
| JAMRA, M | 1 |
| HIRSCH, SR | 1 |
| WANEBO, HJ | 1 |
| CLARKSON, BD | 1 |
| HAGEDORN, AB | 1 |
| MCGUCKIN, WF | 1 |
| Kolyvanos Naumann, U | 1 |
| Käser, L | 1 |
| Vetter, W | 1 |
| Annibali, O | 1 |
| Petrucci, MT | 1 |
| Martini, V | 1 |
| Tirindelli, MC | 1 |
| Levi, A | 1 |
| Fossati, C | 1 |
| Del Bianco, P | 1 |
| Mandelli, F | 1 |
| Foa, R | 1 |
| Avvisati, G | 1 |
| Johnson, SA | 1 |
| Oscier, DG | 1 |
| Levy, V | 1 |
| Jaeger, U | 1 |
| Shin, SJ | 1 |
| Chun, SH | 1 |
| Kim, KO | 1 |
| Kim, MK | 1 |
| Lee, KH | 1 |
| Hyun, MS | 1 |
| Cho, HS | 1 |
| Khalid, S | 1 |
| Adil, SN | 1 |
| Khurshid, M | 1 |
| Kumar, S | 1 |
| Das, S | 1 |
| Goyal, JL | 1 |
| Chauhan, D | 1 |
| Sangit, V | 1 |
| Meier, C | 1 |
| Roberts, K | 1 |
| Steck, A | 1 |
| Hess, C | 1 |
| Miloni, E | 1 |
| Tschopp, L | 1 |
| Richards, JD | 1 |
| Coates, PB | 1 |
| Closs, SP | 1 |
| Tobias, JS | 1 |
| Joannides, T | 1 |
| Dalakas, MC | 1 |
| Flaum, MA | 1 |
| Rick, M | 1 |
| Engel, WK | 1 |
| Gralnick, HR | 1 |
| Horsman, DE | 1 |
| Card, RT | 1 |
| Skinnider, LF | 1 |
| Mashaly, R | 1 |
| Gray, F | 1 |
| Poisson, M | 1 |
| Rancurel, G | 1 |
| Escourolle, R | 1 |
| Buge, A | 1 |
| Emmerich, B | 1 |
| Spencer, SS | 1 |
| Moench, JC | 1 |
| Rausch, PG | 1 |
| Herion, JC | 1 |
| Lindström, FD | 1 |
| Hed, J | 1 |
| Eneström, S | 1 |
| Laurin, S | 1 |
| Maheu, M | 1 |
| Debrie, JC | 1 |
| Lavigne, F | 1 |
| Renambot, J | 1 |
| Quiniou, M | 1 |
| Bolognesi, G | 1 |
| Cordido, M | 1 |
| Fernández-Lago, C | 1 |
| Fernández-Vigo, J | 1 |
| López-Nieto, C | 1 |
| Wagner, DR | 1 |
| Eckert, F | 1 |
| Gresser, U | 1 |
| Landthaler, M | 1 |
| Middeke, M | 1 |
| Zöllner, N | 1 |
| Govindaraju, S | 1 |
| Brochot, P | 1 |
| Ringot, AC | 1 |
| Paternotte, L | 1 |
| Morrone, A | 1 |
| Eschard, JP | 1 |
| Etienne, JC | 1 |
| Facon, T | 1 |
| Brouillard, M | 1 |
| Duhamel, A | 1 |
| Simon, M | 1 |
| Jouet, JP | 1 |
| Bauters, F | 1 |
| Fenaux, P | 1 |
| Patel, TC | 1 |
| Moore, SB | 1 |
| Pineda, AA | 1 |
| Witzig, TE | 2 |
| Dussol, B | 1 |
| Kaplanski, G | 1 |
| Daniel, L | 1 |
| Brunet, P | 1 |
| Pellissier, JF | 1 |
| Berland, Y | 1 |
| Kyle, RA | 1 |
| Greipp, PR | 1 |
| Lust, JA | 1 |
| Lacy, MQ | 1 |
| Therneau, TM | 1 |
| Yonemura, K | 1 |
| Suzuki, T | 1 |
| Sano, K | 1 |
| Fujigaki, Y | 1 |
| Ikegaya, N | 1 |
| Hishida, A | 1 |
| Weinberg, JM | 1 |
| Ioffreda, M | 1 |
| White, SM | 1 |
| Rudolph, RI | 1 |
| Kramer, EM | 1 |
| García-Sanz, R | 1 |
| Montoto, S | 1 |
| Torrequebrada, A | 1 |
| de Coca, AG | 1 |
| Petit, J | 1 |
| Sureda, A | 1 |
| Rodríguez-García, JA | 1 |
| Massó, P | 1 |
| Pérez-Aliaga, A | 1 |
| Monteagudo, MD | 1 |
| Navarro, I | 1 |
| Moreno, G | 1 |
| Toledo, C | 1 |
| Alonso, A | 1 |
| Besses, C | 1 |
| Besalduch, J | 1 |
| Jarque, I | 1 |
| Salama, P | 1 |
| Rivas, JA | 1 |
| Navarro, B | 1 |
| Bladé, J | 2 |
| Miguel, JF | 1 |
| Kyrtsonis, MC | 1 |
| Vassilakopoulos, TP | 1 |
| Angelopoulou, MK | 1 |
| Siakantaris, P | 1 |
| Kontopidou, FN | 1 |
| Dimopoulou, MN | 1 |
| Boussiotis, V | 1 |
| Gribabis, A | 1 |
| Konstantopoulos, K | 1 |
| Vaiopoulos, GA | 1 |
| Fessas, P | 1 |
| Kittas, C | 1 |
| Pangalis, GA | 1 |
| Desikan, KR | 1 |
| Dhodapkar, MV | 1 |
| Barlogie, B | 1 |
| Kuenn, JW | 1 |
| Weber, R | 1 |
| Teague, PO | 1 |
| Keitt, AS | 1 |
| Brouet, JC | 1 |
| Montserrat-Costa, E | 1 |
| Rozman, C | 1 |
| Aranalde, JM | 1 |
| Feliu, E | 1 |
| Grañena, A | 1 |
| Marín, P | 1 |
| Laroche, C | 2 |
| Caquet, R | 2 |
| Festal, G | 1 |
| Cremer, GA | 1 |
| Uro, J | 1 |
| Shulman, G | 1 |
| Lynch, SR | 1 |
| Bezwoda, WR | 1 |
| Gilich, GC | 1 |
| Fuchs, P | 1 |
| Fontana, A | 1 |
| Sulser, H | 1 |
| Hurvitz, AI | 2 |
| MacEwen, EG | 2 |
| Middaugh, CR | 1 |
| Litman, GW | 1 |
| Napoli, VM | 1 |
| Nichols, CW | 1 |
| Wright, RE | 1 |
| Hayes, A | 1 |
| Krausz, Y | 1 |
| Zlotnick, A | 1 |
| Bonilla Velasco, FA | 1 |
| Durantez Martínez, A | 1 |
| Becq-Giraudon, B | 1 |
| Yver, L | 1 |
| Sudre, Y | 1 |
| Hurez, D | 1 |
| Gombert, J | 1 |
| Alcalay, D | 1 |
| Krajny, M | 1 |
| Pruzanski, W | 1 |
| Oluboyede, OA | 1 |
| Bademosi, O | 1 |
| David-West, A | 1 |
| Thomas, CO | 1 |
| Francis, TI | 1 |
| Luzzatto, L | 1 |
| Schubert, JC | 1 |
| Fraser, DM | 1 |
| Parker, AC | 1 |
| Amer, S | 1 |
| Campbell, IW | 1 |
| Mokeeva, RA | 3 |
| Majado, MJ | 1 |
| González García, C | 1 |
| Marín-Blazquez, MD | 1 |
| Morales Lázaro, A | 1 |
| Moreno Moreno, M | 1 |
| Collet, E | 1 |
| Boulitrop-Morvan, C | 1 |
| Dalac, S | 1 |
| Camus, P | 1 |
| Lambert, D | 1 |
| Lossos, A | 1 |
| Averbuch-Heller, L | 1 |
| Reches, A | 1 |
| Abramsky, O | 1 |
| Filuk, RB | 1 |
| Warren, PW | 1 |
| Busnach, G | 1 |
| Dal Col, A | 1 |
| Brando, B | 1 |
| Perrino, ML | 1 |
| Brunatti, C | 1 |
| Minetti, L | 1 |
| Nii, Y | 1 |
| Ogushi, F | 1 |
| Satou, K | 1 |
| Sone, S | 1 |
| Ozaki, T | 1 |
| Kobayashi, H | 1 |
| Yasuoka, S | 1 |
| Ogura, T | 1 |
| Jenkins, EC | 1 |
| Genevrier, R | 1 |
| Gacouin, JC | 1 |
| Baviera, E | 1 |
| Murat, JA | 1 |
| Buchanan, JG | 1 |
| Scott, PJ | 1 |
| McLachlan, EM | 1 |
| Smith, F | 1 |
| Richmond, DE | 1 |
| North, JD | 1 |
| Wuhrmann, F | 1 |
| Märki, HH | 1 |
| Baez Villaseñor, J | 1 |
| Monge Herrera, B | 1 |
| Alarcon Segovia, D | 1 |
| Muñiz, C | 1 |
| Dryll, A | 1 |
| Rousselet, F | 1 |
| Ryckewaert, A | 1 |
| Kahn, MF | 1 |
| Duguet, M | 1 |
| de Sèze, S | 1 |
| Pronk, EA | 1 |
| Elkerbout, F | 1 |
| Klein, F | 1 |
| Radema, H | 1 |
| Cleton, FJ | 1 |
| Major, D | 1 |
| Meltzer, MH | 1 |
| Nedwich, A | 1 |
| Hayes, B | 1 |
| Oaks, WW | 1 |
| Rigo, P | 1 |
| de Leval-Rutten, F | 2 |
| Salmon, J | 1 |
| Ferracci, C | 1 |
| Darracq, R | 1 |
| Bobin, P | 1 |
| Varieras, G | 1 |
| Ruiz, VG | 1 |
| Alexanian, R | 1 |
| Winterbauer, RH | 1 |
| Riggins, RC | 1 |
| Griesman, FA | 1 |
| Bauermeister, DE | 1 |
| Cardamone, JM | 1 |
| Kimmerle, RI | 1 |
| Marshall, EY | 1 |
| Zittoun, R | 1 |
| Lebon, P | 1 |
| Diebold, J | 1 |
| Ota, H | 1 |
| Tanaka, M | 1 |
| Ikeda, Y | 1 |
| Kunii, A | 1 |
| Deshayes, P | 1 |
| Piguet, H | 1 |
| Renier, JC | 1 |
| Delaporte, J | 1 |
| Laumonier, R | 1 |
| Geffroy, Y | 1 |
| Morgenfeld, MC | 2 |
| Helft, F | 2 |
| Bomchil, G | 2 |
| André, R | 1 |
| Duhamel, G | 1 |
| Salmon, C | 1 |
| Najman, A | 1 |
| Homberg, JC | 1 |
| Mongin, M | 1 |
| Kourilsky, R | 1 |
| Kourilsky, S | 1 |
| Piéron, R | 1 |
| Lesobre, B | 1 |
| Bernueau, J | 1 |
| Godeau, P | 1 |
| Sicard, D | 1 |
| Herreman, G | 1 |
| Slama, G | 1 |
| Rubens-Duval, A | 1 |
| Kaplan, G | 1 |
| Nobillot, A | 1 |
| Rabiner, SF | 1 |
| Aprill, SN | 1 |
| Radner, DB | 1 |
| Gouffier, E | 1 |
| Bernheim, P | 1 |
| Cruchaud, A | 1 |
| Hausser, E | 1 |
| Buckle, RM | 1 |
| Jenkins, GC | 1 |
| Mills, GL | 1 |
| Wright, I | 1 |
| Moeschlin, S | 1 |
| Macfarlane, H | 1 |
| Crockson, RA | 1 |
| Jones, JV | 1 |
| Spokes, RM | 1 |
| Rose, MN | 1 |
| Soothill, JF | 1 |
| Romeo, JA | 1 |
| Schmidt, RB | 1 |
| Peters, HA | 1 |
| Rosen, ES | 1 |
| Simmons, AV | 1 |
| Warnes, TW | 1 |
| Klemm, D | 2 |
| Merker, H | 1 |
| Westerhausen, M | 1 |
| Kopp, WL | 1 |
| MacKinney, AA | 1 |
| Wasson, G | 1 |
| Silva, J | 1 |
| Newell, GR | 1 |
| Schlott, DW | 1 |
| Papush, ND | 1 |
| Novikova, EZ | 1 |
| Mémin, Y | 2 |
| Vigne, J | 1 |
| Bouchat, R | 1 |
| Pattin, S | 2 |
| Lechat, S | 1 |
| Castaldi, PA | 1 |
| Penny, R | 1 |
| Presant, CA | 1 |
| Wiernik, PH | 1 |
| Serpick, AA | 1 |
| Bouchat, J | 2 |
| Degos, R | 1 |
| Touraine, R | 1 |
| Jouffroy, L | 1 |
| Revuz, MJ | 1 |
| Szulkin, E | 2 |
| Bromberg-Sznek, S | 2 |
| Wolańska, A | 2 |
| Osterberg, G | 1 |
| Rausing, A | 1 |
| Afifi, AM | 1 |
| Tawfeek, S | 1 |
| Clément, F | 1 |
| Hartwich, G | 1 |
| Butzler, W | 1 |
| Berceanu, S | 1 |
| Gociu, M | 1 |
| Geib, R | 1 |
| Sighetea, E | 1 |
| Dăncescu, I | 1 |
| Segal, E | 1 |
| Tănăsescu, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| US Post-Marketing Retrospective Observational Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITI)(TM)[NCT04125290] | 2 participants (Actual) | Observational | 2019-12-09 | Terminated (stopped due to Study stopped due to lack of recruitment.) | |||
| Randomized Trial Comparing the Efficacy of Chlorambucil to Fludarabine in Patients With Advanced Waldenström Macroglobulinemia,Lymphoplasmacytic Lymphoma or Splenic Marginal Zone Lymphoma[NCT00566332] | Phase 3 | 414 participants (Actual) | Interventional | 2001-06-30 | Completed | ||
| A Randomised Trial of Chlorambucil Versus Fludarabine as Initial Therapy of Waldenström's Macroglobulinaemia and Splenic Lymphoma With Villous Lymphocytes[NCT00608374] | Phase 3 | 400 participants (Anticipated) | Interventional | 2006-06-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for chlorambucil and Waldenstrom Macroglobulinemia
| Article | Year |
|---|---|
Review of clinical trials conducted in Waldenstrom macroglobulinemia and recommendations for reporting clinical trial responses in these patients.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Chlorambucil; Cladribine; Clinical Tr | 2010 |
[Waldenstrom macroglobulinemia].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, M | 2004 |
Role of plasmapheresis in thrombocytopenic purpura associated with Waldenström's macroglobulinemia.
Topics: Aged; Chlorambucil; Humans; Male; Plasmapheresis; Prednisone; Purpura, Thrombocytopenic; Waldenstrom | 1996 |
Treatment options in Waldenström's macroglobulinaemia: the role of the purine analogues.
Topics: Alkylating Agents; Antimetabolites; Chlorambucil; Cladribine; Clinical Trials as Topic; Drug Resista | 2001 |
Waldenström macroglobulinaemia: presenting features and outcome in a series with 217 cases.
Topics: Aged; Antibodies, Anti-Idiotypic; Antibodies, Monoclonal; Antineoplastic Agents, Alkylating; beta 2- | 2001 |
Waldenström's macroglobulinemia.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; beta 2-Microg | 2000 |
[Association of sarcoidosis and Waldenström's macroglobulinemia].
Topics: Chlorambucil; Female; Humans; Middle Aged; Sarcoidosis; Skin Diseases; Waldenstrom Macroglobulinemia | 1992 |
Multiple myeloma and macroglobulinemia. Advances in treatment.
Topics: Anemia; Blood Protein Electrophoresis; Blood Transfusion; Blood Viscosity; Chlorambucil; Drug Therap | 1974 |
6 trials available for chlorambucil and Waldenstrom Macroglobulinemia
| Article | Year |
|---|---|
Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Chromosome Aberrations; Chromos | 2013 |
Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Chromosome Aberrations; Chromos | 2013 |
Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Chromosome Aberrations; Chromos | 2013 |
Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Chromosome Aberrations; Chromos | 2013 |
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma.
Topics: Aged; Antineoplastic Agents; Chlorambucil; Disease-Free Survival; Female; Humans; Kaplan-Meier Estim | 2013 |
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma.
Topics: Aged; Antineoplastic Agents; Chlorambucil; Disease-Free Survival; Female; Humans; Kaplan-Meier Estim | 2013 |
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma.
Topics: Aged; Antineoplastic Agents; Chlorambucil; Disease-Free Survival; Female; Humans; Kaplan-Meier Estim | 2013 |
Results of a randomized trial of chlorambucil versus fludarabine for patients with untreated Waldenström macroglobulinemia, marginal zone lymphoma, or lymphoplasmacytic lymphoma.
Topics: Aged; Antineoplastic Agents; Chlorambucil; Disease-Free Survival; Female; Humans; Kaplan-Meier Estim | 2013 |
IFN-alpha as induction and maintenance treatment of patients newly diagnosed with Waldenström's macroglobulinemia.
Topics: Aged; Chlorambucil; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; | 2002 |
Phase III study of chlorambucil versus fludarabine as initial therapy for Waldenstrom's macroglobulinemia and related disorders.
Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Antineoplastic Agents; Antineoplastic Ag | 2005 |
Waldenström's macroglobulinaemia: a prospective study comparing daily with intermittent oral chlorambucil.
Topics: Aged; Blood Proteins; Chi-Square Distribution; Chlorambucil; Drug Administration Schedule; Female; H | 2000 |
Therapy of macroglobulinaemia. Comparison of the effect of therapy on the level of monoclonal immunoglobulins and on clinical symptoms in four cases of waldenström's macroglobulinaemia and one case of IgA myeloma.
Topics: Agar; Aged; Alkylating Agents; Anemia, Hemolytic; Blood Coagulation Disorders; Blood Protein Disorde | 1969 |
118 other studies available for chlorambucil and Waldenstrom Macroglobulinemia
| Article | Year |
|---|---|
Real-world treatment patterns and outcomes in a national study of veterans with Waldenström macroglobulinemia, 2006-2019.
Topics: Adenine; Antineoplastic Combined Chemotherapy Protocols; Bendamustine Hydrochloride; Bortezomib; Chl | 2021 |
Increased incidence of transformation and myelodysplasia/acute leukemia in patients with Waldenström macroglobulinemia treated with nucleoside analogs.
Topics: Adult; Aged; Aged, 80 and over; Cell Transformation, Neoplastic; Chlorambucil; Cladribine; Female; F | 2009 |
Erythrocyte survival tests in cases of anti-AnWj antibodies.
Topics: Anemia, Hemolytic; Blood Group Antigens; Blood Group Incompatibility; Chlorambucil; Coombs Test; Ery | 2009 |
Keratotic vascular papules over the feet: a case of Waldenström's macroglobulinaemia-associated cutaneous macroglobulinosis.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Fluorescent Antibody | 2010 |
What's new in Waldenström macroglobulinemia.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Chlorambucil; Cladribine; Clinical Tr | 2010 |
Unresolved issues in the comparison of therapies and determination of responses in Waldenström macroglobulinemia.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Chlorambucil; Cladribine; Clinical Tr | 2010 |
Resolution of Waldenström's macroglubulinemia related isolated neutropenia by immunochemotherapy.
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil | 2011 |
Waldenström's macroglobulinemia in a dog with a bleeding diathesis.
Topics: Animals; Antineoplastic Agents; Blood Cell Count; Bone Marrow; Chlorambucil; Diarrhea; Disease Susce | 2011 |
Chemotherapy-related magnetic resonance imaging abnormalities mimicking disease progression following intraventricular liposomal cytarabine and high dose methotrexate for neurolymphomatosis.
Topics: Aged; Antineoplastic Agents; Autopsy; Brain; Brain Injuries; Chlorambucil; Cytarabine; Disease Progr | 2012 |
Splenic re-irradiation for waldenstrőm's macroglobulinemia.
Topics: Aged; Antineoplastic Agents; Chlorambucil; Combined Modality Therapy; Cyclophosphamide; Disease Prog | 2012 |
Waldenstrom's macroglobulinemia: is there a place and time for a cease-fire?
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy | 2003 |
Waldenstrom's macroglobulinemia: a retrospective analysis of 40 patients from 1972 to 2001.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Chlorambucil; Female; Humans; Male; Middle Ag | 2003 |
Continuous chlorambucil therapy in primary macroglobulinemia of Waldenstrom: report of four cases.
Topics: Chlorambucil; Globulins; Mechlorethamine; Nitrogen Mustard Compounds; Serum Globulins; Waldenstrom M | 1961 |
Response to chlorambucil in macroglobulinemia.
Topics: Chlorambucil; Humans; Waldenstrom Macroglobulinemia | 1963 |
Treatment of macroglobulinaemia.
Topics: Chlorambucil; Humans; Mechlorethamine; Waldenstrom Macroglobulinemia | 1963 |
WALDENSTROM'S MACROGLOBULINEMIA WITH DIFFUSE PULMONARY INFILTRATION: LUNG BIOPSY AND RESPONSE TO CHLORAMBUCIL THERAPY.
Topics: Biopsy; Blood Protein Electrophoresis; Chlorambucil; Humans; Lung Diseases; Radiography, Thoracic; R | 1963 |
MELPHALAN THERAPY IN MYELOMATOSIS.
Topics: Chlorambucil; Erythrocyte Count; Geriatrics; Humans; Melphalan; Multiple Myeloma; Prognosis; Protein | 1964 |
[TREATMENT OF WALDENSTROEM'S MACROGLOBULINEMIA].
Topics: Blood Cell Count; Blood Coagulation Tests; Blood Protein Electrophoresis; Blood Viscosity; Chlorambu | 1963 |
MACROGLOBULINEMIA.
Topics: Chlorambucil; Diagnosis; Electrophoresis; Humans; Penicillin G; Penicillins; Waldenstrom Macroglobul | 1964 |
ESSENTIAL MACROGLOBULINEMIA. REPORT OF A CASE INCLUDING IMMUNOFLUORESCENT AND ELECTRON MICROSCOPIC STUDIES.
Topics: Blood Protein Electrophoresis; Bone Marrow Cells; Chlorambucil; Electrons; Fluorescent Antibody Tech | 1965 |
MACROGLOBULINEMIA, ITS RECOGNITION AND TREATMENT.
Topics: Blood Sedimentation; Bone Marrow Cells; Chlorambucil; Chromatography; Diagnosis; Drug Therapy; Hemog | 1965 |
Treatment of 72 newly diagnosed Waldenstrom macroglobulinemia cases with oral melphalan, cyclophosphamide, and prednisone: results and cost analysis.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols | 2005 |
Myelodysplastic syndrome with complex karyotypic abnormality in a patient with Waldenström's macroglobulinemia after sequential treatment with chlorambucil and fludarabine.
Topics: Aged; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow | 2005 |
Waldenstrom's macroglobulinemia terminating in acute myeloid leukemia.
Topics: Adult; Chlorambucil; Cyclophosphamide; Humans; Leukemia, Myeloid, Acute; Male; Waldenstrom Macroglob | 2006 |
Bilateral orbital tumor formation and isolated facial palsy in Waldenstrom's macroglobulinemia.
Topics: Adult; Antineoplastic Agents, Alkylating; Biopsy, Fine-Needle; Chlorambucil; Diagnosis, Differential | 2005 |
Polyneuropathy in Waldenström's macroglobulinaemia: reduction of endoneurial IgM-deposits after treatment with chlorambucil and plasmapheresis.
Topics: Chlorambucil; Humans; Immunoglobulin M; Male; Middle Aged; Peripheral Nerves; Peripheral Nervous Sys | 1984 |
Case of macroglobulinaemia treated with hemibody irradiation.
Topics: Aged; Chlorambucil; Humans; Male; Methods; Waldenstrom Macroglobulinemia | 1983 |
Treatment of polyneuropathy in Waldenström's macroglobulinemia: role of paraproteinemia and immunologic studies.
Topics: B-Lymphocytes; Chlorambucil; Female; Humans; Immunoglobulin M; Middle Aged; Neurons; Peripheral Nerv | 1983 |
Waldenström macroglobulinemia terminating in acute leukemia: a report of three cases.
Topics: Aged; Chlorambucil; Cyclophosphamide; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; | 1983 |
[Acquired cerebral toxoplasmosis in adults. Clinical and neuropathologic study].
Topics: Aged; Biopsy; Brain; Brain Diseases; Chlorambucil; Diagnostic Errors; Female; Humans; Immunosuppress | 1983 |
[Therapy of malignant gammopathies].
Topics: Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Humans; Hypergammaglobulinemia; Melphalan | 1984 |
Progressive and treatable cerebellar ataxia in macroglobulinemia.
Topics: Cerebellar Ataxia; Chlorambucil; Humans; Male; Middle Aged; Waldenstrom Macroglobulinemia | 1980 |
Pulmonary manifestations of Waldenstrom macroglobulinemia.
Topics: Adult; Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Lung Diseases; Lung Neoplasms; Male; Mi | 1980 |
Renal pathology of Waldenström's macroglobulinaemia with monoclonal antiglomerular antibodies and nephrotic syndrome.
Topics: Aged; Autoantibodies; Chlorambucil; Humans; Immunoglobulin M; Kidney; Kidney Glomerulus; Male; Nephr | 1980 |
[Von Willebrand's disease associated with Waldenström's macroglobulinemia].
Topics: Aged; Chlorambucil; Female; Humans; von Willebrand Diseases; Waldenstrom Macroglobulinemia | 1980 |
[Pseudotumoral localization of Waldenström's disease in the nasal cavity (apropos of a case)].
Topics: Chlorambucil; Humans; Male; Middle Aged; Nose Neoplasms; Waldenstrom Macroglobulinemia | 1980 |
[Hairy cell leukemia].
Topics: Chlorambucil; Diagnosis, Differential; Heavy Chain Disease; Humans; Leukemia, Hairy Cell; Leukemia, | 1982 |
Dry eye in Waldenström's macroglobulinemia. Improvement after systemic chemotherapy.
Topics: Chlorambucil; Drug Therapy, Combination; Dry Eye Syndromes; Humans; Lacrimal Apparatus; Male; Middle | 1995 |
Deposits of paraprotein in small vessels as a cause of skin ulcers in Waldenström's macroglobulinemia.
Topics: Aged; Artifacts; Blood Viscosity; Chlorambucil; Cryoglobulinemia; Cyclophosphamide; Fluocortolone; H | 1993 |
[Chronic urticaria-macroglobulinemia (Schnitzler syndrome): developing to IgM myeloma. Apropos of a case].
Topics: Adrenal Cortex Hormones; Aged; Chlorambucil; Chronic Disease; Humans; Immunoglobulin M; Male; Multip | 1993 |
Prognostic factors in Waldenström's macroglobulinemia: a report of 167 cases.
Topics: Aged; Cause of Death; Chlorambucil; Female; Humans; Male; Middle Aged; Multivariate Analysis; Progno | 1993 |
Simultaneous occurrence of fibrillary glomerulopathy and AL amyloid.
Topics: Amyloid; Amyloidosis; Antineoplastic Agents, Alkylating; Biopsy; Chlorambucil; Follow-Up Studies; Gl | 1998 |
A case with acute renal failure complicated by Waldenström's macroglobulinemia and cryoglobulinemia.
Topics: Acute Kidney Injury; Chlorambucil; Combined Modality Therapy; Cryoglobulinemia; Follow-Up Studies; H | 2000 |
Purplish papules on the legs. Diagnosis: type I cryoglobulinemia in association with WM.
Topics: Aged; Betamethasone; Chlorambucil; Cryoglobulinemia; Diagnosis, Differential; Drug Therapy, Combinat | 2000 |
Waldenström's macroglobulinemia: clinical course and prognostic factors in 60 patients. Experience from a single hematology unit.
Topics: Adult; Aged; Aged, 80 and over; Blood Viscosity; Cardiac Output, Low; Chlorambucil; Fatigue; Female; | 2001 |
Cryopathic gangrene with an IgM lambda cryoprecipitating cold agglutinin.
Topics: Adult; Agglutinins; Autoantibodies; Breast Neoplasms; Chlorambucil; Cryoglobulins; Female; Gangrene; | 1978 |
[Waldenström's macroglobulinemia].
Topics: Adrenal Cortex Hormones; B-Lymphocytes; Chlorambucil; Humans; Immunoglobulin M; Plasmapheresis; Wald | 1979 |
[Pleural involvement in macroglobulinaemia. Report of a case and a review of the literature (author's transl)].
Topics: Aged; Chlorambucil; Diagnosis, Differential; Humans; Male; Pleural Effusion; Radiography; Waldenstro | 1979 |
[Gastric and pleural localization of Waldenström's disease].
Topics: Chlorambucil; Female; Humans; Immunoglobulin M; Jejunum; Middle Aged; Pleura; Pleurisy; Stomach; Sto | 1975 |
Serum beta-lipoprotein and other specific protein concentrations in patients with immunocytoma.
Topics: Aged; Blood Protein Electrophoresis; Blood Proteins; Chlorambucil; Cholesterol; Female; Follow-Up St | 1976 |
[Waldenström's macroglobulinemia with immunocytoma of the lung].
Topics: Chlorambucil; Humans; Lung Neoplasms; Male; Middle Aged; Plasmacytoma; Prednisone; Waldenstrom Macro | 1977 |
Monoclonal cryoglobulinemia with macroglobulinemia in a dog.
Topics: Animals; Blood Proteins; Chlorambucil; Cryoglobulins; Dog Diseases; Dogs; Female; Immunoglobulin M; | 1977 |
Malignant lymphoma of thenasopharyns in waldenström's macroglobulinemia: report of a case with severe epistaxis.
Topics: Chlorambucil; Cobalt Radioisotopes; Epistaxis; Female; Humans; Lymphoma; Middle Aged; Nasopharyngeal | 1977 |
Hyperviscosity syndrome associated with lymphocytic leukemia in three dogs.
Topics: Animals; Blood Viscosity; Chlorambucil; Dog Diseases; Dogs; Immunoglobulin A; Immunoglobulin M; Leuk | 1977 |
Macroglobulinemia of Waldenström associated with severe osteolytic lesions.
Topics: Aged; Bone Resorption; Chlorambucil; Female; Humans; Leukemia, Lymphoid; Osteolysis; Waldenstrom Mac | 1977 |
[Macroglobulinemia: report on 11 patients].
Topics: Aged; Chlorambucil; Humans; Immunoglobulin M; Middle Aged; Waldenstrom Macroglobulinemia | 1978 |
[Waldenstrom's disease associated with Sjögren's syndrome. Double IgM population (lambda and kappa). Response to chlorambucil].
Topics: Chlorambucil; Female; Humans; Immunoglobulin M; Middle Aged; Sjogren's Syndrome; Waldenstrom Macrogl | 1976 |
Waldenström's macroglobulinemia: review of 45 cases.
Topics: Adult; Aged; Bence Jones Protein; Bone Marrow; Chlorambucil; Cyclophosphamide; Female; Follow-Up Stu | 1976 |
Monoclonal gammopathy (Waldenström's macroglobulinaemia) producing specific red cell antibody.
Topics: Adolescent; Agglutinins; Autoantibodies; Chlorambucil; Cold Temperature; Hemagglutinins; Humans; I B | 1976 |
[Therapy of Waldenstrom's disease and of heavy chain disease].
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Chlorambucil; Cyclophosphamide; Drug Therapy, | 1976 |
Mononeuritis multiplex in a patient with macroglobulinaemia.
Topics: Aged; Blood Viscosity; Chlorambucil; Cranial Nerves; Electroencephalography; Humans; Male; Motor Neu | 1976 |
[Treatment of Waldenstrom's macroglobulinemia].
Topics: Chlorambucil; Cyclophosphamide; Evaluation Studies as Topic; Humans; Plasmapheresis; Waldenstrom Mac | 1976 |
[Appearance of a chronic myeloid leukemia in Waldenström's macroglobulinemia].
Topics: Busulfan; Chlorambucil; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; | 1992 |
Complete unilateral ophthalmoplegia as the presenting manifestation of Waldenström's macroglobulinemia.
Topics: Aged; Chlorambucil; Humans; Male; Ophthalmoplegia; Waldenstrom Macroglobulinemia | 1990 |
Bronchoalveolar lavage in Waldenström's macroglobulinaemia with pulmonary infiltrates.
Topics: Adult; Bronchi; Chlorambucil; Humans; Male; Pulmonary Alveoli; Therapeutic Irrigation; Waldenstrom M | 1986 |
Efficacy of a combined treatment with plasma exchange and cytostatics in macroglobulinemia.
Topics: Chlorambucil; Combined Modality Therapy; Humans; Immunoglobulins; Plasma Exchange; Waldenstrom Macro | 1986 |
[A case of pulmonary Waldenstrom's macroglobulinemia].
Topics: Biopsy; Chlorambucil; Cyclophosphamide; Humans; Immunoglobulin M; Lung; Lung Diseases; Male; Middle | 1988 |
Waldenstrom's macroglobulinaemia and phytohaemagglutinin response.
Topics: Aged; Chlorambucil; Humans; Lectins; Lymphocyte Activation; Male; Waldenstrom Macroglobulinemia | 1972 |
[Pathological changes in the respiratory tract in Waldenström's macroglobulinemia. Example of 5 observations].
Topics: Aged; Chlorambucil; Diagnosis, Differential; Female; gamma-Globulins; Humans; Immunoelectrophoresis; | 1974 |
A chromosome translocation in association with periarteritis nodosa and macroglobulinemia.
Topics: Anemia; Arthritis; Blood Proteins; Chlorambucil; Chromosome Aberrations; Chromosome Disorders; Diaph | 1967 |
[Therapy of Waldenström disease].
Topics: Anemia, Hemolytic; Antineoplastic Agents; Blood Viscosity; Chlorambucil; Cyclophosphamide; gamma-Glo | 1968 |
[Waldenstrom's macroglobulinemia. Review of the literature and report of a clinical case].
Topics: Aged; Chlorambucil; Female; gamma-Globulins; Humans; Waldenstrom Macroglobulinemia | 1967 |
[Inflammatory rheumatisms and paraproteins excepting myeloma and Waldenström's disease. Study of 18 personal cases of this association].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Blood Protein Disorders; Chlorambucil; Electrophoresi | 1969 |
Waldenstrom's macroglobulinemia presenting as a pulmonary mass.
Topics: Biopsy, Needle; Bone Marrow Examination; Chlorambucil; Humans; Lung; Lung Diseases; Male; Middle Age | 1973 |
[Diagnosis and treatment of Waldenstrom's macroglobulinemia].
Topics: Adult; Aged; Chlorambucil; Female; Humans; Male; Middle Aged; Waldenstrom Macroglobulinemia | 1973 |
[Mixed IgM-IgG cryoglobulinemia in a patient with Waldenstrom's macroglobulinemia].
Topics: Amputation, Surgical; Biopsy; Bone and Bones; Chlorambucil; Cryoglobulins; Dextrans; Edema; Female; | 1974 |
[Case of Waldenström's disease with predominantly digestive symptomatology].
Topics: Adult; Chlorambucil; Diarrhea; Gastric Mucosa; Hepatomegaly; Humans; Immunoglobulin A; Immunoglobuli | 1974 |
[A case of allergic vascularitis].
Topics: Antigen-Antibody Complex; Biopsy; Chlorambucil; Dextrans; Female; Fingers; Gangrene; Humans; Immunoe | 1974 |
Pleuropulmonary manifestations of Waldenstrom's macroglobulinemia.
Topics: Aged; Chlorambucil; Female; Humans; Lung; Lung Diseases; Lymphocytes; Male; Middle Aged; Pleura; Ple | 1974 |
Development of acute erythroleukemia in B-cell immunoproliferative disorders after prolonged therapy with alkylating drugs.
Topics: Aged; Alkylating Agents; Biopsy; Bone Marrow; Chlorambucil; Female; Humans; Leukemia, Erythroblastic | 1974 |
[Sjögren's syndrome with pseudolymphoma].
Topics: Biopsy; Chlorambucil; Diagnosis, Differential; Female; Hodgkin Disease; Humans; Lymph Nodes; Lymphat | 1974 |
[A case of Sjögren's syndrome associated with macroglobulinemia which responded excellently to chlorambucil].
Topics: Adult; Chlorambucil; Female; Humans; Sjogren's Syndrome; Waldenstrom Macroglobulinemia | 1974 |
[Waldenström's disease. Rheumatologic manifestations].
Topics: Aged; Blood Coagulation Disorders; Chlorambucil; Eye Manifestations; Female; Humans; Joint Diseases; | 1968 |
[Different response of the superficial and deep lymph nodes to therapy in malignant lymphoreticulopathies].
Topics: Adult; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Lymphatic Metastasis; Lym | 1968 |
[Autoimmune hemolytic anemia with lymphatic nodules in the bone marrow].
Topics: Aged; Anemia, Hemolytic, Autoimmune; Autoantibodies; Bone Marrow; Bone Marrow Examination; Chlorambu | 1968 |
[Waldenström's macroglobulinemia].
Topics: Aged; Chlorambucil; Diagnosis, Differential; Eye Manifestations; Female; Humans; Immunoglobulin M; M | 1969 |
[Waldenström's disease and pulmonary images. 2 cases].
Topics: Blood Sedimentation; Chlorambucil; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; | 1970 |
[Waldenström's macroglobulinemia with pleuropulmonary, orbital and subcutaneous localisation. Favorable effect of chlorambucil].
Topics: Aged; Biopsy; Bronchial Diseases; Chlorambucil; Humans; Immunoelectrophoresis; Lung; Lung Diseases; | 1972 |
[Cryoglobulins, macroglobulins and the Gougerot-Sjogren syndrome. Treatment with chlorambucil and cyclophosphamide].
Topics: Arthritis; Biopsy; Blood Protein Disorders; Bone Marrow; Chlorambucil; Cryoglobulins; Cyclophosphami | 1974 |
Waldenström's macroglobulinemia. Report of a case with pulmonary involvement and improvement in pulmonary symptoms only following chlorambucil therapy.
Topics: Chlorambucil; Female; Humans; Immunoglobulin M; Immunoglobulins; Lung; Lymphocytes; Middle Aged; Wal | 1972 |
[Waldenström's macroglobulinemia with gastric and pleural localization].
Topics: Chlorambucil; Female; Humans; Immunoelectrophoresis; Laparotomy; Macroglobulins; Middle Aged; Pleuri | 1972 |
[Waldenström's macroglobulinemia].
Topics: Chlorambucil; Humans; Male; Middle Aged; Raynaud Disease; Waldenstrom Macroglobulinemia | 1965 |
Waldenström's macroglobulinaemia treated with cylophosphamide and chlorambucil.
Topics: Chlorambucil; Cyclophosphamide; Female; Humans; Middle Aged; Waldenstrom Macroglobulinemia | 1966 |
Waldenström's macroglobulinaemia: a cause of epistaxis in the elderly.
Topics: Aged; Blood Sedimentation; Blood Transfusion; Chlorambucil; Epistaxis; Humans; Male; Methenolone; Pl | 1966 |
Macroglobulinemia Waldenström with miliary lunginfiltrations and terminal plasmacell-leukemia. (Chlorambuci induced clinical remission despite autoradiographically persistant DNA- and RNA-synthesis).
Topics: Aged; Autoradiography; Biopsy; Bone Marrow Examination; Chlorambucil; DNA; Female; Humans; Immunoele | 1966 |
C-reactive protein in macroglobulinaemia and multiple myelomatosis.
Topics: Arthritis, Rheumatoid; C-Reactive Protein; Chemistry, Clinical; Chlorambucil; Humans; Immunodiffusio | 1966 |
Primary macroglobulinemia: report of a case and clinical discussion.
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic; Blood Proteins; Blood Sedimentation; Chlorambucil; Femal | 1967 |
Spinal muscular atrophy secondary to macroglobulinemia. Reversal of symptoms with chlorambucil therapy.
Topics: Blood Protein Electrophoresis; Blood Proteins; Bone Marrow; Chlorambucil; Electromyography; Humans; | 1968 |
Retinopathy of Waldenström's macroglobulinemia: photographic assessment.
Topics: Aneurysm; Angiography; Atrophy; Blood Transfusion; Blood Viscosity; Capillaries; Chlorambucil; Densi | 1968 |
[Acute new proliferation inparaproteinemic hemoblastoses during long-term treatment with cytostatic agents].
Topics: Aged; Blood Sedimentation; Chlorambucil; Cyclophosphamide; Female; Humans; Immunoelectrophoresis; Ma | 1968 |
Blood volume and hematocrit value in macroglobulinemia and myeloma.
Topics: Antineoplastic Agents; Blood Protein Electrophoresis; Blood Proteins; Blood Volume; Blood Volume Det | 1969 |
[Paraproteinemic diseases].
Topics: Anemia, Hemolytic; Blood Protein Disorders; Chlorambucil; Cryoglobulins; Cyclophosphamide; Diagnosis | 1969 |
Macroglobulinemia associated with subcutaneous tumors: report of two cases.
Topics: Aged; Blood Proteins; Blood Viscosity; Chlorambucil; Extremities; Humans; Lung Diseases; Lymphocytes | 1969 |
[Tumor transformations in macroglobulinemic reticulosis].
Topics: Adult; Chlorambucil; Female; Humans; Lymphatic Diseases; Middle Aged; Waldenstrom Macroglobulinemia | 1969 |
[Osseous and osteoarticular manifestations associated with Waldenstrom's disease. Favorable prognosis for dysglobulinemia under the influence of chlorambucil].
Topics: Aged; Bone Diseases; Chlorambucil; Humans; Joint Diseases; Male; Waldenstrom Macroglobulinemia | 1969 |
A macroglobulin with inhibitory activity against coagulation factor VIII.
Topics: Adsorption; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Transfusion; Chlorambucil; C | 1970 |
Disseminated extrapulmonary nocardiosis presenting as a renal abscess.
Topics: Abscess; Adult; Anemia, Hemolytic, Autoimmune; Autopsy; Brain Diseases; Chlorambucil; Diagnosis, Dif | 1970 |
[Orbital tumor and dysglobulinemia].
Topics: Aged; Chlorambucil; Female; Humans; Orbital Neoplasms; Plasmacytoma; Waldenstrom Macroglobulinemia | 1969 |
[Waldenström's macroglobulinemia with bullous lesions. Disappearance of cutaneous manifestations after treatment with chloraminophene].
Topics: Blister; Chlorambucil; Humans; Male; Skin Manifestations; Waldenstrom Macroglobulinemia | 1969 |
[Osseous and osteo-articular manifestations in Waldenstrom's disease, ophthalmologic and developmental aspects. 2 cases].
Topics: Aged; Bone Diseases; Chlorambucil; Chorioretinitis; Electrophoresis; Female; Humans; Joint Diseases; | 1970 |
[Different response of superficial and deep lymph nodes to drug therapy in malignant lymphoreticulopathy].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Leukemia, Lymphoid; Lymph Nodes; Lymphoma, Lar | 1969 |
[Syndrome of blood hyperviscosity in macrocryogelglobulinemia].
Topics: Blood Sedimentation; Blood Viscosity; Chlorambucil; Eye Manifestations; Female; Humans; Immunoelectr | 1970 |
Reticulum cell sarcoma in Waldenström's macroglobulinemia after chlorambucil treatment.
Topics: Amyloidosis; Bone Marrow Cells; Bone Neoplasms; Chlorambucil; Female; Humans; Lymphoma, Non-Hodgkin; | 1970 |
Deafness due to Waldenstrom macroglobulinaemia.
Topics: Audiometry; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Proteins; Chlorambucil; Deaf | 1971 |
[Modern hematology. Sidero-achrestic anemias, polyglobulias, chemotherapy].
Topics: Adenoma; Adolescent; Adult; Aged; Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Sideroblastic; Bl | 1971 |
[Leukeran in treatment of macroglobulinemia].
Topics: Chlorambucil; Female; Humans; Middle Aged; Remission, Spontaneous; Waldenstrom Macroglobulinemia | 1971 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
[Results and current biological bases of therapy of malignant hemoreticulopathies].
Topics: Antineoplastic Agents; Chlorambucil; Cortisone; Cyclophosphamide; Humans; Hydrazines; Leukemia; Lymp | 1971 |