chlorambucil has been researched along with Vasculitis in 8 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Vasculitis: Inflammation of any one of the blood vessels, including the ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Of three patients with lung-biopsy-proven benign lymphocytic angiitis and granulomatosis, two experienced complete resolution of their disease from therapy with chlorambucil and one underwent spontaneous remission with no drug therapy after lung biopsy and removal of a benign spindle cell thymoma." | 3.67 | Benign lymphocytic angiitis and granulomatosis: experience with three cases. ( Colby, TV; DeRemee, RA; Gracey, DR; Unni, KK; Weiland, LH, 1988) |
| " In 1976 she developed a mixed cryoglobulinemia and an immune complex mediated vasculitis manifested by purpura and neuropathy which improved on prednisone and chlorambucil therapy." | 3.66 | Behçet's disease associated with a lymphoproliferative disorder, mixed cryoglobulinemia, and an immune complex mediated vasculitis. ( Houston, KA; McDuffie, FC; O'duffy, JD, 1978) |
| "Azathioprine is a valuable alternative to slow-acting antirheumatic drugs in older patients with rheumatoid arthritis." | 2.38 | Azathioprine, cyclophosphamide and chlorambucil. ( Bacon, PA; Luqmani, RA; Palmer, RG, 1990) |
| "If the vasculitis is secondary to an underlying disease, such as lymphoma, therapy should be directed at the primary disease." | 2.37 | Pulmonary vasculitis. ( Fauci, AS; Leavitt, RY, 1986) |
| "Urticarial vasculitis is a form of cutaneous leukocytoclastic vasculitis clinically characterized by persistent and often painful urticarial lesions." | 1.33 | Plasmapheresis for refractory urticarial vasculitis in a patient with B-cell chronic lymphocytic leukemia. ( Alexander, JL; Kalaaji, AN; Pittelkow, MR; Shehan, JM; Yokel, BK, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, JL | 1 |
| Kalaaji, AN | 1 |
| Shehan, JM | 1 |
| Yokel, BK | 1 |
| Pittelkow, MR | 1 |
| Valente, RM | 1 |
| Conn, DL | 1 |
| Taylor, HG | 1 |
| Samanta, A | 1 |
| Houston, KA | 1 |
| O'duffy, JD | 1 |
| McDuffie, FC | 1 |
| Luqmani, RA | 1 |
| Palmer, RG | 1 |
| Bacon, PA | 1 |
| Leavitt, RY | 1 |
| Fauci, AS | 1 |
| Gracey, DR | 1 |
| DeRemee, RA | 1 |
| Colby, TV | 1 |
| Unni, KK | 1 |
| Weiland, LH | 1 |
| Nashel, DJ | 1 |
5 reviews available for chlorambucil and Vasculitis
| Article | Year |
|---|---|
Current therapies for systemic vasculitis.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Dapsone; Humans; Immunization, Passive; | 1994 |
Treatment of vasculitis.
Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Azathioprine; Chlorambucil; Combined Modality Thera | 1993 |
Azathioprine, cyclophosphamide and chlorambucil.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Connective Tissue Diseases; Cyclophosphamide; Hum | 1990 |
Pulmonary vasculitis.
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cy | 1986 |
Mechanisms of action and clinical applications of cytotoxic drugs in rheumatic disorders.
Topics: Arthritis, Reactive; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Collagen Diseases; Cyclophos | 1985 |
3 other studies available for chlorambucil and Vasculitis
| Article | Year |
|---|---|
Plasmapheresis for refractory urticarial vasculitis in a patient with B-cell chronic lymphocytic leukemia.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mal | 2006 |
Behçet's disease associated with a lymphoproliferative disorder, mixed cryoglobulinemia, and an immune complex mediated vasculitis.
Topics: Antigen-Antibody Complex; Behcet Syndrome; Chlorambucil; Cryoglobulins; Female; Follow-Up Studies; H | 1978 |
Benign lymphocytic angiitis and granulomatosis: experience with three cases.
Topics: Aged; Chlorambucil; Female; Humans; Lung Neoplasms; Lymphomatoid Granulomatosis; Middle Aged; Precan | 1988 |