chlorambucil has been researched along with Vascular Diseases in 10 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 7.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 3.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| "The excess risk of cancer after chlorambucil appears to persist for 5 years after stopping this treatment." | 1.29 | The very-long-term course of polycythaemia: a complement to the previously published data of the Polycythaemia Vera Study Group. ( Dresch, C; Najean, Y; Rain, JD, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Geltner, D | 1 |
| Kohn, RW | 1 |
| Gorevic, P | 1 |
| Franklin, EC | 1 |
| Najean, Y | 1 |
| Dresch, C | 1 |
| Rain, JD | 1 |
| Dinning, WJ | 1 |
| Perkins, ES | 1 |
| Pivetti Pezzi, P | 1 |
| Gasparri, V | 1 |
| De Liso, P | 1 |
| Catarinelli, G | 1 |
| Golde, D | 1 |
| Epstein, W | 1 |
| Rafii, MR | 1 |
| Betow, C | 1 |
| Snaith, ML | 1 |
| Holt, JM | 1 |
| Oliver, DO | 1 |
| Dunnill, MS | 1 |
| Halley, W | 1 |
| Stephenson, AC | 1 |
| Abdalla, MI | 1 |
| el-D Bahoat, N | 1 |
| Lévèque, B | 1 |
| Debauchez, C | 1 |
| Deflandre, L | 1 |
| Marie, J | 1 |
| Lewis, FB | 1 |
| Schwartz, RS | 1 |
| Dameshek, W | 1 |
10 other studies available for chlorambucil and Vascular Diseases
| Article | Year |
|---|---|
The effect of combination therapy (steroids, immunosuppressives, and plasmapheresis) on 5 mixed cryoglobulinemia patients with renal, neurologic, and vascular involvement.
Topics: Aged; Chlorambucil; Cryoglobulinemia; Female; Humans; Kidney Diseases; Male; Middle Aged; Paraprotei | 1981 |
The very-long-term course of polycythaemia: a complement to the previously published data of the Polycythaemia Vera Study Group.
Topics: Aged; Bloodletting; Chlorambucil; Follow-Up Studies; Humans; Middle Aged; Neoplasms; Phosphorus Radi | 1994 |
Immunosuppressives in uveitis. A preliminary report of experience with chlorambucil.
Topics: Adult; Behcet Syndrome; Chlorambucil; Endophthalmitis; Female; Follow-Up Studies; Humans; Leukopenia | 1975 |
Prognosis in Behcet's disease.
Topics: Adolescent; Adult; Behcet Syndrome; Central Nervous System Diseases; Chlorambucil; Eye Diseases; Fem | 1985 |
Mixed cryoglobulins and glomerulonephritis.
Topics: Beta-Globulins; Chlorambucil; Creatinine; Cryoglobulins; Fluorescent Antibody Technique; gamma-Globu | 1968 |
[Wegener's granulomatosis. Contribution to the diagnosis, therapy and course].
Topics: Aged; Chlorambucil; Cyclophosphamide; Female; Glomerulonephritis; Granulomatosis with Polyangiitis; | 1974 |
Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil.
Topics: Adult; Alopecia; Amenorrhea; Azathioprine; Biopsy; Bone Marrow; Chlorambucil; Cyclophosphamide; Cyst | 1973 |
Long-lasting remission of Behcet's disease after chlorambucil therapy.
Topics: Adrenal Cortex Hormones; Adult; Arthritis; Behcet Syndrome; Chlorambucil; Erythema Nodosum; Female; | 1973 |
[Chlorambucil in the treatment of idiopathic nephrotic syndrome without glomrular lesions in childhood. Apropos of 30 cases].
Topics: Adolescent; Anemia; Biopsy; Child; Child, Preschool; Chlorambucil; Female; Glucocorticoids; Humans; | 1969 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1966 |