chlorambucil has been researched along with Uveomeningoencephalitic Syndrome in 6 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Uveomeningoencephalitic Syndrome: A syndrome characterized by bilateral granulomatous UVEITIS with IRITIS and secondary GLAUCOMA, premature ALOPECIA, symmetrical VITILIGO, poliosis circumscripta (a strand of depigmented hair), HEARING DISORDERS, and meningeal signs (neck stiffness and headache). Examination of the cerebrospinal fluid reveals a pattern consistent with MENINGITIS, ASEPTIC. (Adams et al., Principles of Neurology, 6th ed, p748; Surv Ophthalmol 1995 Jan;39(4):265-292)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intensive and prolonged systemic treatment with corticosteroids is recommended for the patients with first attack of VKH syndrome, where as regular treatment with chlorambucil is useful for control of chronic and recurrent uveitis seen in VKH syndrome." | 3.71 | [Therapeutic regimen in Vogt-Koyanagi-Harada syndrome]. ( Fu, T; Huang, X; Li, F; Wang, H; Yang, P; Zhong, H; Zhou, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, R | 1 |
| Chen, L | 1 |
| Su, G | 1 |
| Du, L | 1 |
| Qin, Y | 1 |
| Xu, J | 1 |
| Tan, H | 1 |
| Zhou, C | 1 |
| Cao, Q | 1 |
| Yuan, G | 1 |
| Kijlstra, A | 1 |
| Yang, P | 2 |
| Wang, H | 1 |
| Zhou, H | 1 |
| Zhong, H | 2 |
| Li, F | 1 |
| Huang, X | 1 |
| Fu, T | 1 |
| Cunningham, ET | 1 |
| Demetrius, R | 1 |
| Frieden, IJ | 1 |
| Emery, HM | 1 |
| Irvine, AR | 1 |
| Good, WV | 1 |
| Dinning, WJ | 1 |
| Perkins, ES | 1 |
| Johnston, CA | 1 |
| Teitelbaum, CS | 1 |
| Godfrey, WA | 1 |
| Epstein, WV | 1 |
| O'Connor, GR | 1 |
| Kimura, SJ | 1 |
| Hogan, MJ | 1 |
| Nozik, RA | 1 |
6 other studies available for chlorambucil and Uveomeningoencephalitic Syndrome
| Article | Year |
|---|---|
Identification of Ribosomal Protein S4, Y-Linked 1 as a cyclosporin A plus corticosteroid resistance gene.
Topics: Adult; Cells, Cultured; Chlorambucil; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Gluc | 2020 |
[Therapeutic regimen in Vogt-Koyanagi-Harada syndrome].
Topics: Adolescent; Adult; Child; Chlorambucil; Female; Follow-Up Studies; Glucocorticoids; Humans; Male; Me | 2002 |
Vogt-Koyanagi-Harada syndrome in a 4-year old child.
Topics: Alopecia; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Blindness; Child, Preschool; | 1995 |
Immunosuppressives in uveitis. A preliminary report of experience with chlorambucil.
Topics: Adult; Behcet Syndrome; Chlorambucil; Endophthalmitis; Female; Follow-Up Studies; Humans; Leukopenia | 1975 |
Magnetic resonance imaging in Vogt-Koyanagi-Harada syndrome.
Topics: Administration, Oral; Adult; Chlorambucil; Diagnosis, Differential; Female; Humans; Magnetic Resonan | 1990 |
The use of chlorambucil in intractable idiopathic uveitis.
Topics: Adolescent; Arthritis, Rheumatoid; Behcet Syndrome; Blood Cell Count; Blood Platelets; Chemical Phen | 1974 |