chlorambucil has been researched along with Thymoma in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Thymoma: A neoplasm originating from thymic tissue, usually benign, and frequently encapsulated. Although it is occasionally invasive, metastases are extremely rare. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (previously termed granulomatous thymoma), should not be regarded as thymoma. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "A cell-surface localizing xenogeneic antibody against an AKR mouse lymphoma of spontaneous origin could be bound to chlorambucil without interference with either the alkylating activity of chlorambucil or the immunologic reactivity of the antibody." | 7.65 | Suppression of an AKR lymphoma by antibody and chlorambucil. ( Ghose, T; Guclu, A; Tai, J, 1975) |
| "A cell-surface localizing xenogeneic antibody against an AKR mouse lymphoma of spontaneous origin could be bound to chlorambucil without interference with either the alkylating activity of chlorambucil or the immunologic reactivity of the antibody." | 3.65 | Suppression of an AKR lymphoma by antibody and chlorambucil. ( Ghose, T; Guclu, A; Tai, J, 1975) |
| " Radical excision of the tumor, if possible, and the remaining thymus, high dosage alternate day prednisone, and radiation therapy, if indicated, seem the treatments of choice." | 1.25 | Myasthenia gravis and invasive thymoma: a 20-year experience. ( Brown, WJ; Goldman, AJ; Herrmann, C; Keesey, JC; Mulder, DG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| STEEL, SJ | 1 |
| Ghose, T | 1 |
| Guclu, A | 1 |
| Tai, J | 1 |
| Goldman, AJ | 1 |
| Herrmann, C | 1 |
| Keesey, JC | 1 |
| Mulder, DG | 1 |
| Brown, WJ | 1 |
| Smyth, MJ | 1 |
| Pietersz, GA | 1 |
| Classon, BJ | 1 |
| McKenzie, IF | 1 |
4 other studies available for chlorambucil and Thymoma
| Article | Year |
|---|---|
HODGKIN'S DISEASE OF THE LUNG WITH CAVITATION.
Topics: Antineoplastic Agents; Chlorambucil; Diagnosis, Differential; Hodgkin Disease; Lung Neoplasms; Mechl | 1964 |
Suppression of an AKR lymphoma by antibody and chlorambucil.
Topics: Animals; Antibodies, Neoplasm; Chlorambucil; Female; Fluorescent Antibody Technique; Immunization, P | 1975 |
Myasthenia gravis and invasive thymoma: a 20-year experience.
Topics: Adult; Aged; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Middle Aged; Myasthenia Gravis; N | 1975 |
Specific targeting of chlorambucil to tumors with the use of monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Chlorambucil; Mice; Mice, Inbred Strains; Neoplasm Trans | 1986 |