chlorambucil has been researched along with Teratoma in 47 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)
Excerpt | Relevance | Reference |
---|---|---|
"Based on the diagnosis of testicular neoplasm, orchiectomy was performed on September 7, 1983." | 1.27 | [Case report of a non-seminomatous testicular neoplasm indicating marked efficacy of a combination chemotherapy of VBL, ACTD, BLM, CDDP and EX (VAB-4 combination therapy)]. ( Ebihara, K; Hayashi, M; Urano, E, 1984) |
"Sixteen patients with metastatic testicular cancer were treated with combination chemotherapy including cisplatin (CDDP) at 3- to 4-week intervals for two to five courses." | 1.27 | [Hypomagnesemia following chemotherapy of disseminated testicular tumors]. ( Hida, S; Nishimura, K; Nishio, Y; Okada, K; Okada, Y; Yoshida, O, 1988) |
"The histologic diagnoses were six immature teratomas, five endodermal sinus tumors, four mixed germ cell tumors, and one nongestational choriocarcinoma." | 1.27 | Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary. ( Cain, JM; Hakes, TB; Lewis, JL; Pierce, VK; Pippitt, CH, 1988) |
"Primary testicular neoplasms are not common childhood tumors, comprising about 1% of all childhood malignancies [1]." | 1.26 | Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management. ( Chu, JY; DeMello, D; McElfresh, AE; O'Connor, DM; Razek, AA, 1978) |
"Of 250 testicular tumors treated up to May 1975 233 (93." | 1.26 | The combined surgical and chemotherapeutic approach to non-seminomatous cancer of the testicle. ( Vahlensieck, W; Weissbach, L, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 44 (93.62) | 18.7374 |
1990's | 3 (6.38) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
ROSENBLATT, MS | 1 |
YANOFF, M | 1 |
RAWSON, AJ | 1 |
LEBHERZ, TB | 1 |
HUSTON, JW | 1 |
AUSTIN, JA | 1 |
BOYCE, CR | 1 |
APPERT, O | 1 |
EDMONDS, LC | 1 |
CARRERA, GM | 1 |
Mackenzie, AR | 1 |
Laplante, MP | 1 |
Mount, BM | 1 |
Vugrin, D | 3 |
Whitmore, WF | 3 |
Golbey, RB | 4 |
Williams, SD | 1 |
Loehrer, PJ | 1 |
Einhorn, LH | 1 |
Hayashi, M | 1 |
Ebihara, K | 1 |
Urano, E | 1 |
Sablińska, B | 1 |
Chu, JY | 1 |
O'Connor, DM | 1 |
DeMello, D | 1 |
Razek, AA | 1 |
McElfresh, AE | 1 |
Vahlensieck, W | 4 |
Weissbach, L | 3 |
Smith, JP | 1 |
Rutledge, F | 1 |
Rodermund, OE | 1 |
Brock, PR | 1 |
Yeomans, EC | 1 |
Bellman, SC | 1 |
Pritchard, J | 1 |
Tiuliandin, SA | 1 |
Honda, N | 1 |
Uchida, T | 1 |
Mukai, N | 1 |
Go, M | 1 |
Yokoyama, E | 1 |
Mashimo, S | 1 |
Endo, T | 1 |
Ishibashi, A | 1 |
Koshiba, K | 1 |
Shibuya, M | 1 |
Toumieux, B | 1 |
Lemarie, E | 1 |
Lavandier, M | 1 |
Hida, S | 1 |
Nishimura, K | 1 |
Nishio, Y | 1 |
Okada, Y | 1 |
Okada, K | 1 |
Yoshida, O | 1 |
Masuda, F | 1 |
Nakada, J | 1 |
Kondo, N | 1 |
Takahashi, T | 1 |
Mochizuki, A | 1 |
Iizuka, N | 1 |
Pippitt, CH | 1 |
Cain, JM | 1 |
Hakes, TB | 1 |
Pierce, VK | 1 |
Lewis, JL | 1 |
Iwasaki, M | 1 |
Kazama, T | 1 |
Nakada, T | 1 |
Katayama, T | 1 |
Le Duc, A | 1 |
Gisselbrecht, C | 1 |
Le Doze, H | 1 |
Mignot, L | 1 |
Gödde, S | 1 |
Skinner, DG | 2 |
Leadbetter, WF | 2 |
Wilkins, EW | 1 |
Wilms, K | 2 |
Bonadonna, G | 1 |
van der Werf-Messing, B | 1 |
Rathert, P | 1 |
Terhorst, B | 1 |
Lutzeyer, W | 1 |
Astrakhan, VI | 1 |
Monul, FA | 1 |
Woodruff, JD | 2 |
Protos, P | 1 |
Peterson, WF | 1 |
Ryssel, HJ | 1 |
Sonntag, RW | 1 |
Brunner, KW | 1 |
Furnari, S | 1 |
Pavone-Macaluso, M | 1 |
Veroux, G | 1 |
Mattea, E | 1 |
Dees, JE | 1 |
Nogales, FF | 1 |
Oliva, HA | 1 |
Julian, CG | 1 |
Hartwich, G | 1 |
Butzler, W | 1 |
Ansfield, FJ | 1 |
Korbitz, BC | 1 |
Davis, HL | 1 |
Ramirez, G | 1 |
Moore, CA | 1 |
Wider, JA | 1 |
Marshall, JR | 1 |
Bardin, CW | 1 |
Lipsett, MB | 1 |
Ross, GT | 1 |
3 reviews available for chlorambucil and Teratoma
Article | Year |
---|---|
[A case report of extragonadal germ cell tumor with special reference to VAB-6 therapy].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Chlorambucil; C | 1988 |
Chemotherapy of testicular tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Chlorambucil; Dactinomycin; Dysgermin | 1971 |
The role of chemotherapy in the treatment of primary ovarian malignancy.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl | 1969 |
2 trials available for chlorambucil and Teratoma
Article | Year |
---|---|
[Chemotherapy of immature ovarian teratomas].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as | 1983 |
Advances in chemotherapy for gynecologic cancer.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug | 1975 |
42 other studies available for chlorambucil and Teratoma
Article | Year |
---|---|
Chemical treatment of metastatic malignant teratoma of the testicle.
Topics: Chlorambucil; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Nitrofurazone; Terato | 1963 |
PELIOSIS HEPATIS. AN ANATOMIC STUDY WITH DEMONSTRATION OF TWO VARIETIES.
Topics: Anatomy; Chlorambucil; Classification; Cyclophosphamide; Dactinomycin; Femoral Fractures; Geriatrics | 1964 |
SUSTAINED PALLIATION IN OVARIAN CARCINOMA.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Carcinoma; Chlorambucil; Dysgerminoma; Female; Gr | 1965 |
[CYTOSTATIC TREATMENT OF A MALIGNANT EMBRYONAL MIXED TESTICULAR TUMOR].
Topics: Chlorambucil; Dactinomycin; Drug Therapy; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metas | 1965 |
EXTRAGENITAL CHORIOCARCINOMA.
Topics: Autopsy; Brain Neoplasms; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Drug Therapy; Epistaxi | 1965 |
Chemotherapy of metastatic testis cancer. Results in 154 patients.
Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Choriocarcinoma; Dactinomycin; Dy | 1966 |
Lymphadenectomy for testicular carcinoma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chor | 1982 |
VAB-6 combination chemotherapy without maintenance in treatment of disseminated cancer of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1983 |
VAB-5 combination chemotherapy in prognostically poor risk patients with germ cell tumors.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisp | 1983 |
Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum combination chemotherapy in metastatic testis cancer--a 1-year program.
Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; | 1982 |
Chemotherapy of advanced testicular cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit | 1984 |
[Case report of a non-seminomatous testicular neoplasm indicating marked efficacy of a combination chemotherapy of VBL, ACTD, BLM, CDDP and EX (VAB-4 combination therapy)].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; | 1984 |
Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management.
Topics: Castration; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Inf | 1978 |
The combined surgical and chemotherapeutic approach to non-seminomatous cancer of the testicle.
Topics: Chlorambucil; Dactinomycin; Drug Therapy, Combination; Dysgerminoma; Humans; Ifosfamide; Lymph Node | 1977 |
[Effect of a cytostatic triple-drug-interval therapy on human germinal epithelium].
Topics: Adult; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Age | 1975 |
Cisplatin therapy in infants: short and long-term morbidity.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chlorambucil; Cisplatin; | 1992 |
[Infusion of high doses of platidiam in the treatment of patients with germ cell testicular tumors].
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1990 |
[A case of retrovesical embryonal cell carcinoma].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined | 1991 |
[Non seminomatous germ cell tumors of the mediastinum treated successfully by the chemotherapy and surgical excision combination].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; | 1988 |
[Hypomagnesemia following chemotherapy of disseminated testicular tumors].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis | 1988 |
[Treatment of nonseminomatous testicular tumor with liver metastases].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis | 1988 |
Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chorioca | 1988 |
[Role of chemotherapy in the treatment of cancer of the testis in adults].
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis | 1985 |
[Transperitoneal lymph node excision and cytostatic postoperative treatment of malignant germinal testicular neoplasms].
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Synergism; Dysgerminoma; Humans; Lymph Node | 1968 |
The surgical management of testis tumors metastatic to the lung: a report of 10 cases with subsequent resection of from one to seven pulmonary metastases.
Topics: Adolescent; Adult; Castration; Child; Chlorambucil; Dactinomycin; Follow-Up Studies; Humans; Lung Ne | 1971 |
[Cytostatic treatment of malignant testicular neoplasms].
Topics: Adult; Antibiotics, Antineoplastic; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; D | 1971 |
[Cytostatic therapy of malignant testicular tumors].
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Dysgerminoma; Humans; Male; Methotrexate; Plicamy | 1973 |
The treatment of pulmonary metastases of malignant teratoma of the testis.
Topics: Chlorambucil; Dactinomycin; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Pneumon | 1973 |
[Bleomycin for malignant tumours of the genitals of the male (author's transl)].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil | 1974 |
[The combined chemotherapy of testicular tumors resistant to sarcolysin].
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; | 1967 |
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin | 1968 |
[Treatment of choriocarcinoma and malignant testicular neoplasms in internal medicine].
Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Humans; Lung Neoplasms; | 1967 |
Cancer chemotherapy in urology.
Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal | 1971 |
Operative and cytostatic treatment of germinal tumours of the testis.
Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Child, Preschool; Chlorambucil; Cyclic | 1973 |
Metastatic embryonal cell carcinoma of testis: an apparent 8-year cure.
Topics: Adult; Chlorambucil; Dactinomycin; Humans; Lung Neoplasms; Lymphography; Male; Methotrexate; Neoplas | 1973 |
Peritoneal gliomatosis produced by ovarian teratomas.
Topics: Adult; Chlorambucil; Dactinomycin; Fallopian Tubes; Female; Glioma; Humans; Hysterectomy; Methotrexa | 1974 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
The surgical management of testis tumors.
Topics: Adolescent; Adult; Castration; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin; | 1971 |
Triple drug therapy in testicular tumors.
Topics: Adolescent; Adult; Chlorambucil; Choriocarcinoma; Dactinomycin; Humans; Male; Methotrexate; Middle A | 1969 |
The place of chemotherapy in the treatment of testicular tumors.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadot | 1970 |
Triple chemotherapy in the treatment of metastatic testicular neoplasms.
Topics: Adult; Chlorambucil; Choriocarcinoma; Dactinomycin; Humans; Male; Methotrexate; Neoplasm Metastasis; | 1968 |
Sustained remissions after chemotherapy for primary ovarian cancers containing choriocarcinoma.
Topics: Adolescent; Adult; Child; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Dysge | 1969 |