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chlorambucil and Teratoma

chlorambucil has been researched along with Teratoma in 47 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Teratoma: A true neoplasm composed of a number of different types of tissue, none of which is native to the area in which it occurs. It is composed of tissues that are derived from three germinal layers, the endoderm, mesoderm, and ectoderm. They are classified histologically as mature (benign) or immature (malignant). (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1642)

Research Excerpts

ExcerptRelevanceReference
"Based on the diagnosis of testicular neoplasm, orchiectomy was performed on September 7, 1983."1.27[Case report of a non-seminomatous testicular neoplasm indicating marked efficacy of a combination chemotherapy of VBL, ACTD, BLM, CDDP and EX (VAB-4 combination therapy)]. ( Ebihara, K; Hayashi, M; Urano, E, 1984)
"Sixteen patients with metastatic testicular cancer were treated with combination chemotherapy including cisplatin (CDDP) at 3- to 4-week intervals for two to five courses."1.27[Hypomagnesemia following chemotherapy of disseminated testicular tumors]. ( Hida, S; Nishimura, K; Nishio, Y; Okada, K; Okada, Y; Yoshida, O, 1988)
"The histologic diagnoses were six immature teratomas, five endodermal sinus tumors, four mixed germ cell tumors, and one nongestational choriocarcinoma."1.27Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary. ( Cain, JM; Hakes, TB; Lewis, JL; Pierce, VK; Pippitt, CH, 1988)
"Primary testicular neoplasms are not common childhood tumors, comprising about 1% of all childhood malignancies [1]."1.26Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management. ( Chu, JY; DeMello, D; McElfresh, AE; O'Connor, DM; Razek, AA, 1978)
"Of 250 testicular tumors treated up to May 1975 233 (93."1.26The combined surgical and chemotherapeutic approach to non-seminomatous cancer of the testicle. ( Vahlensieck, W; Weissbach, L, 1977)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199044 (93.62)18.7374
1990's3 (6.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ROSENBLATT, MS1
YANOFF, M1
RAWSON, AJ1
LEBHERZ, TB1
HUSTON, JW1
AUSTIN, JA1
BOYCE, CR1
APPERT, O1
EDMONDS, LC1
CARRERA, GM1
Mackenzie, AR1
Laplante, MP1
Mount, BM1
Vugrin, D3
Whitmore, WF3
Golbey, RB4
Williams, SD1
Loehrer, PJ1
Einhorn, LH1
Hayashi, M1
Ebihara, K1
Urano, E1
Sablińska, B1
Chu, JY1
O'Connor, DM1
DeMello, D1
Razek, AA1
McElfresh, AE1
Vahlensieck, W4
Weissbach, L3
Smith, JP1
Rutledge, F1
Rodermund, OE1
Brock, PR1
Yeomans, EC1
Bellman, SC1
Pritchard, J1
Tiuliandin, SA1
Honda, N1
Uchida, T1
Mukai, N1
Go, M1
Yokoyama, E1
Mashimo, S1
Endo, T1
Ishibashi, A1
Koshiba, K1
Shibuya, M1
Toumieux, B1
Lemarie, E1
Lavandier, M1
Hida, S1
Nishimura, K1
Nishio, Y1
Okada, Y1
Okada, K1
Yoshida, O1
Masuda, F1
Nakada, J1
Kondo, N1
Takahashi, T1
Mochizuki, A1
Iizuka, N1
Pippitt, CH1
Cain, JM1
Hakes, TB1
Pierce, VK1
Lewis, JL1
Iwasaki, M1
Kazama, T1
Nakada, T1
Katayama, T1
Le Duc, A1
Gisselbrecht, C1
Le Doze, H1
Mignot, L1
Gödde, S1
Skinner, DG2
Leadbetter, WF2
Wilkins, EW1
Wilms, K2
Bonadonna, G1
van der Werf-Messing, B1
Rathert, P1
Terhorst, B1
Lutzeyer, W1
Astrakhan, VI1
Monul, FA1
Woodruff, JD2
Protos, P1
Peterson, WF1
Ryssel, HJ1
Sonntag, RW1
Brunner, KW1
Furnari, S1
Pavone-Macaluso, M1
Veroux, G1
Mattea, E1
Dees, JE1
Nogales, FF1
Oliva, HA1
Julian, CG1
Hartwich, G1
Butzler, W1
Ansfield, FJ1
Korbitz, BC1
Davis, HL1
Ramirez, G1
Moore, CA1
Wider, JA1
Marshall, JR1
Bardin, CW1
Lipsett, MB1
Ross, GT1

Reviews

3 reviews available for chlorambucil and Teratoma

ArticleYear
[A case report of extragonadal germ cell tumor with special reference to VAB-6 therapy].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Bleomycin; Chlorambucil; C

1988
Chemotherapy of testicular tumors.
    Acta chirurgica Belgica, 1971, Volume: 70, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Chlorambucil; Dactinomycin; Dysgermin

1971
The role of chemotherapy in the treatment of primary ovarian malignancy.
    Obstetrical & gynecological survey, 1969, Volume: 24, Issue:11

    Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl

1969

Trials

2 trials available for chlorambucil and Teratoma

ArticleYear
[Chemotherapy of immature ovarian teratomas].
    Ginekologia polska, 1983, Volume: 54, Issue:10

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as

1983
Advances in chemotherapy for gynecologic cancer.
    Cancer, 1975, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug

1975

Other Studies

42 other studies available for chlorambucil and Teratoma

ArticleYear
Chemical treatment of metastatic malignant teratoma of the testicle.
    Northwest medicine, 1963, Volume: 62

    Topics: Chlorambucil; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Nitrofurazone; Terato

1963
PELIOSIS HEPATIS. AN ANATOMIC STUDY WITH DEMONSTRATION OF TWO VARIETIES.
    Archives of pathology, 1964, Volume: 77

    Topics: Anatomy; Chlorambucil; Classification; Cyclophosphamide; Dactinomycin; Femoral Fractures; Geriatrics

1964
SUSTAINED PALLIATION IN OVARIAN CARCINOMA.
    Obstetrics and gynecology, 1965, Volume: 25

    Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Carcinoma; Chlorambucil; Dysgerminoma; Female; Gr

1965
[CYTOSTATIC TREATMENT OF A MALIGNANT EMBRYONAL MIXED TESTICULAR TUMOR].
    Schweizerische medizinische Wochenschrift, 1965, Mar-27, Volume: 95

    Topics: Chlorambucil; Dactinomycin; Drug Therapy; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metas

1965
EXTRAGENITAL CHORIOCARCINOMA.
    The Journal of pediatrics, 1965, Volume: 67

    Topics: Autopsy; Brain Neoplasms; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Drug Therapy; Epistaxi

1965
Chemotherapy of metastatic testis cancer. Results in 154 patients.
    Cancer, 1966, Volume: 19, Issue:10

    Topics: Adult; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Choriocarcinoma; Dactinomycin; Dy

1966
Lymphadenectomy for testicular carcinoma.
    Canadian journal of surgery. Journal canadien de chirurgie, 1982, Volume: 25, Issue:3

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chor

1982
VAB-6 combination chemotherapy without maintenance in treatment of disseminated cancer of the testis.
    Cancer, 1983, Jan-15, Volume: 51, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin;

1983
VAB-5 combination chemotherapy in prognostically poor risk patients with germ cell tumors.
    Cancer, 1983, Mar-15, Volume: 51, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisp

1983
Vinblastine, actinomycin D, bleomycin, cyclophosphamide and cis-platinum combination chemotherapy in metastatic testis cancer--a 1-year program.
    The Journal of urology, 1982, Volume: 128, Issue:6

    Topics: Adolescent; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bleomycin;

1982
Chemotherapy of advanced testicular cancer.
    Seminars in urology, 1984, Volume: 2, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined Modalit

1984
[Case report of a non-seminomatous testicular neoplasm indicating marked efficacy of a combination chemotherapy of VBL, ACTD, BLM, CDDP and EX (VAB-4 combination therapy)].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1984, Volume: 11, Issue:12 Pt 2

    Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil;

1984
Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management.
    Medical and pediatric oncology, 1978, Volume: 4, Issue:2

    Topics: Castration; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Doxorubicin; Humans; Inf

1978
The combined surgical and chemotherapeutic approach to non-seminomatous cancer of the testicle.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1977, Issue:60

    Topics: Chlorambucil; Dactinomycin; Drug Therapy, Combination; Dysgerminoma; Humans; Ifosfamide; Lymph Node

1977
[Effect of a cytostatic triple-drug-interval therapy on human germinal epithelium].
    Zeitschrift fur Hautkrankheiten, 1975, Apr-01, Volume: 50, Issue:7

    Topics: Adult; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Humans; Male; Methotrexate; Middle Age

1975
Cisplatin therapy in infants: short and long-term morbidity.
    The British journal of cancer. Supplement, 1992, Volume: 18

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Chlorambucil; Cisplatin;

1992
[Infusion of high doses of platidiam in the treatment of patients with germ cell testicular tumors].
    Voprosy onkologii, 1990, Volume: 36, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide

1990
[A case of retrovesical embryonal cell carcinoma].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1991, Volume: 82, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combined

1991
[Non seminomatous germ cell tumors of the mediastinum treated successfully by the chemotherapy and surgical excision combination].
    Annales de chirurgie, 1988, Volume: 42, Issue:2

    Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil;

1988
[Hypomagnesemia following chemotherapy of disseminated testicular tumors].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis

1988
[Treatment of nonseminomatous testicular tumor with liver metastases].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:2

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis

1988
Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary.
    Gynecologic oncology, 1988, Volume: 31, Issue:2

    Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chorioca

1988
[Role of chemotherapy in the treatment of cancer of the testis in adults].
    Presse medicale (Paris, France : 1983), 1985, Feb-09, Volume: 14, Issue:5

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Choriocarcinoma; Cis

1985
[Transperitoneal lymph node excision and cytostatic postoperative treatment of malignant germinal testicular neoplasms].
    Langenbecks Archiv fur Chirurgie, 1968, Volume: 322

    Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Synergism; Dysgerminoma; Humans; Lymph Node

1968
The surgical management of testis tumors metastatic to the lung: a report of 10 cases with subsequent resection of from one to seven pulmonary metastases.
    The Journal of urology, 1971, Volume: 105, Issue:2

    Topics: Adolescent; Adult; Castration; Child; Chlorambucil; Dactinomycin; Follow-Up Studies; Humans; Lung Ne

1971
[Cytostatic treatment of malignant testicular neoplasms].
    Deutsche medizinische Wochenschrift (1946), 1971, Nov-26, Volume: 96, Issue:48

    Topics: Adult; Antibiotics, Antineoplastic; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; D

1971
[Cytostatic therapy of malignant testicular tumors].
    Minerva medica, 1973, Mar-14, Volume: 64, Issue:14

    Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Dysgerminoma; Humans; Male; Methotrexate; Plicamy

1973
The treatment of pulmonary metastases of malignant teratoma of the testis.
    Clinical radiology, 1973, Volume: 24, Issue:1

    Topics: Chlorambucil; Dactinomycin; Humans; Lung Neoplasms; Male; Methotrexate; Neoplasm Metastasis; Pneumon

1973
[Bleomycin for malignant tumours of the genitals of the male (author's transl)].
    Der Urologe. Ausg. A, 1974, Volume: 13, Issue:2

    Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Bleomycin; Carcinoma, Squamous Cell; Chlorambucil

1974
[The combined chemotherapy of testicular tumors resistant to sarcolysin].
    Voprosy onkologii, 1967, Volume: 13, Issue:4

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide;

1967
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
    American journal of obstetrics and gynecology, 1968, Nov-01, Volume: 102, Issue:5

    Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin

1968
[Treatment of choriocarcinoma and malignant testicular neoplasms in internal medicine].
    Helvetica medica acta. Supplementum, 1967, May-28, Volume: 47

    Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dysgerminoma; Humans; Lung Neoplasms;

1967
Cancer chemotherapy in urology.
    Urologia internationalis, 1971, Volume: 26, Issue:4

    Topics: Adenocarcinoma; Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites; Chlorambucil; Cobal

1971
Operative and cytostatic treatment of germinal tumours of the testis.
    International urology and nephrology, 1973, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Antineoplastic Agents; Castration; Child; Child, Preschool; Chlorambucil; Cyclic

1973
Metastatic embryonal cell carcinoma of testis: an apparent 8-year cure.
    The Journal of urology, 1973, Volume: 110, Issue:1

    Topics: Adult; Chlorambucil; Dactinomycin; Humans; Lung Neoplasms; Lymphography; Male; Methotrexate; Neoplas

1973
Peritoneal gliomatosis produced by ovarian teratomas.
    Obstetrics and gynecology, 1974, Volume: 43, Issue:6

    Topics: Adult; Chlorambucil; Dactinomycin; Fallopian Tubes; Female; Glioma; Humans; Hysterectomy; Methotrexa

1974
[Secondary tumors in hemoblastoses during cytostatic treatment].
    Medizinische Klinik, 1971, Oct-22, Volume: 66, Issue:43

    Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo

1971
The surgical management of testis tumors.
    The Journal of urology, 1971, Volume: 106, Issue:1

    Topics: Adolescent; Adult; Castration; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin;

1971
Triple drug therapy in testicular tumors.
    Cancer, 1969, Volume: 24, Issue:3

    Topics: Adolescent; Adult; Chlorambucil; Choriocarcinoma; Dactinomycin; Humans; Male; Methotrexate; Middle A

1969
The place of chemotherapy in the treatment of testicular tumors.
    JAMA, 1970, Jul-06, Volume: 213, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadot

1970
Triple chemotherapy in the treatment of metastatic testicular neoplasms.
    The Journal of urology, 1968, Volume: 100, Issue:4

    Topics: Adult; Chlorambucil; Choriocarcinoma; Dactinomycin; Humans; Male; Methotrexate; Neoplasm Metastasis;

1968
Sustained remissions after chemotherapy for primary ovarian cancers containing choriocarcinoma.
    The New England journal of medicine, 1969, Jun-26, Volume: 280, Issue:26

    Topics: Adolescent; Adult; Child; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Dysge

1969