chlorambucil has been researched along with Stomach Neoplasms in 15 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Stomach Neoplasms: Tumors or cancer of the STOMACH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aetiological association between MALT lymphomas and Helicobacter pylori is well established." | 2.74 | Chlorambucil versus observation after anti-Helicobacter therapy in gastric MALT lymphomas: results of the international randomised LY03 trial. ( Ambrosetti, A; Burton, C; Capella, C; Cavalli, F; Copie-Bergman, C; Cortelazzo, S; Delchier, JC; Ferreri, AJ; Gisselbrecht, C; Hancock, BW; Jakupovic, I; Levy, M; Linch, D; Martinelli, G; Pinotti, G; Qian, W; Smith, P; Souhami, R; Traulle, C; Vitolo, U; Wotherspoon, A; Zucca, E, 2009) |
| "Localized MALT lymphomas have excellent prognosis following moderate-dose RT." | 1.31 | Stage I and II MALT lymphoma: results of treatment with radiotherapy. ( Bezjak, A; Crump, M; Gospodarowicz, MK; Hodgson, DC; Pintilie, M; Tsang, RW; Wells, W, 2001) |
| "Low-grade B-cell MALT lymphoma was diagnosed by histologic and immunohistologic examination of endoscopic biopsies." | 1.29 | Efficacy of single-agent chemotherapy in low-grade B-cell mucosa-associated lymphoid tissue lymphoma with prominent gastric expression. ( Chaumette, MT; Delchier, JC; Divine, M; Gaulard, P; Haioun, C; Hammel, P; Reyes, F, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (33.33) | 18.7374 |
| 1990's | 4 (26.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hancock, BW | 1 |
| Qian, W | 1 |
| Linch, D | 1 |
| Delchier, JC | 4 |
| Smith, P | 1 |
| Jakupovic, I | 1 |
| Burton, C | 1 |
| Souhami, R | 1 |
| Wotherspoon, A | 1 |
| Copie-Bergman, C | 3 |
| Capella, C | 2 |
| Traulle, C | 2 |
| Levy, M | 3 |
| Cortelazzo, S | 1 |
| Ferreri, AJ | 1 |
| Ambrosetti, A | 1 |
| Pinotti, G | 2 |
| Martinelli, G | 1 |
| Vitolo, U | 1 |
| Cavalli, F | 2 |
| Gisselbrecht, C | 1 |
| Zucca, E | 2 |
| Mirabile, A | 1 |
| Devizzi, L | 1 |
| Gianni, AM | 1 |
| Cabras, A | 1 |
| Carbone, A | 1 |
| Amiot, A | 1 |
| Dupuis, J | 1 |
| Le Baleur, Y | 1 |
| Belhadj, K | 1 |
| Hémery, F | 2 |
| Sobhani, I | 1 |
| Delfau-Larue, MH | 1 |
| Leroy, K | 1 |
| Haioun, C | 2 |
| Novik, AA | 1 |
| Denisov, NL | 1 |
| Gershanovich, ML | 1 |
| Pozharisskiĭ, KM | 1 |
| Gorodokin, I | 1 |
| LOPESCARDOZO, E | 1 |
| Hammel, P | 1 |
| Chaumette, MT | 1 |
| Gaulard, P | 2 |
| Divine, M | 1 |
| Reyes, F | 1 |
| Roggero, E | 1 |
| Pascarella, A | 1 |
| Bertoni, F | 1 |
| Savio, A | 1 |
| Savio, E | 1 |
| Pedrinis, E | 1 |
| Saletti, P | 1 |
| Morandi, E | 1 |
| Santandrea, G | 1 |
| Bornand-Rousselot, A | 1 |
| Saint-Jean, O | 1 |
| Leblond, V | 1 |
| Tsang, RW | 1 |
| Gospodarowicz, MK | 1 |
| Pintilie, M | 1 |
| Bezjak, A | 1 |
| Wells, W | 1 |
| Hodgson, DC | 1 |
| Crump, M | 1 |
| Lavergne-Slove, A | 1 |
| Brousse, N | 1 |
| Flejou, JF | 1 |
| de Mascarel, A | 1 |
| Barranco, SC | 1 |
| Weintraub, B | 1 |
| MacLean, KK | 1 |
| Beasley, EG | 1 |
| Jenkins, VK | 1 |
| Townsend, CM | 1 |
| Comis, RL | 1 |
| Carter, SK | 1 |
| Lebacq, E | 1 |
| Bessot, M | 1 |
| Brouant, JF | 1 |
| Laurent, J | 1 |
| Macinot, C | 1 |
| Barry, RE | 1 |
| Salmon, PR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Protocol for a Randomised Trial of Observation Versus Chlorambucil After Anti-Helicobacter Therapy in Low Grade Gastric Lymphoma[NCT00003617] | Phase 3 | 200 participants (Anticipated) | Interventional | 1995-03-31 | Active, not recruiting | ||
| Phase III Trial of S-1 and Cisplatin (3 Weekly) Versus S-1 and Oxaliplatin Combination Chemotherapy for First Line Treatment of Advanced Gastric Cancer[NCT01671449] | Phase 3 | 338 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for chlorambucil and Stomach Neoplasms
| Article | Year |
|---|---|
[Helicobacter pylori infection and gastric MALT lymphoma: present-day approaches to research and treatment].
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Chr | 2002 |
A review of chemotherapy in gastric cancer.
Topics: Adenocarcinoma; Antineoplastic Agents; Carmustine; Chlorambucil; Chromomycins; Cyclophosphamide; Cyt | 1974 |
3 trials available for chlorambucil and Stomach Neoplasms
| Article | Year |
|---|---|
Chlorambucil versus observation after anti-Helicobacter therapy in gastric MALT lymphomas: results of the international randomised LY03 trial.
Topics: Aged; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Disease-Free Survival; | 2009 |
Clinical features, treatment and outcome in a series of 93 patients with low-grade gastric MALT lymphoma.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Antineopla | 1997 |
Conservative treatment of primary gastric low-grade B-cell lymphoma of mucosa-associated lymphoid tissue: predictive factors of response and outcome.
Topics: Adult; Aged; Amoxicillin; Antineoplastic Agents, Alkylating; Biopsy, Needle; Chlorambucil; Clarithro | 2002 |
10 other studies available for chlorambucil and Stomach Neoplasms
| Article | Year |
|---|---|
MALT lymphoma and Kaposi sarcoma in an HIV-negative patient.
Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, | 2010 |
Rituximab and chlorambucil versus rituximab alone in gastric mucosa-associated lymphoid tissue lymphoma according to t(11;18) status: a monocentric non-randomized observational study.
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chem | 2013 |
[CYTOSTATIC THERAPY].
Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambucil; Colchicine; Cyclophosphamide; Femal | 1964 |
Efficacy of single-agent chemotherapy in low-grade B-cell mucosa-associated lymphoid tissue lymphoma with prominent gastric expression.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Chlorambuci | 1995 |
Sequential chlorambucil and prednisone as second line therapy in gastric malt lymphoma resistant to Helicobacter pylori eradication. A case report in an octogenarian patient.
Topics: Aged; Aged, 80 and over; Chlorambucil; Drug Therapy, Combination; Female; Helicobacter Infections; H | 1998 |
Stage I and II MALT lymphoma: results of treatment with radiotherapy.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Co | 2001 |
Relationship between glutathione levels and drug or radiation sensitivities in human gastric cancer cell lines in vitro.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Chlorambucil; Cyclophosphamide; Doxor | 1991 |
[Gastric localizations of chronic lymphoid leukemia].
Topics: Adult; Chlorambucil; Duodenal Neoplasms; Duodenal Ulcer; Gastric Mucosa; Hematemesis; Humans; Hyperp | 1969 |
[Lymphoid tumor of the stomach].
Topics: Chlorambucil; Female; Humans; Lymphocytosis; Lymphography; Lymphoma, Non-Hodgkin; Middle Aged; Stoma | 1969 |
Recurrent leukaemoid reaction in pernicious anaemia complicated by gastric carcinoma.
Topics: Adenocarcinoma; Anemia, Pernicious; Chlorambucil; Chronic Disease; Diagnosis, Differential; Female; | 1969 |