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chlorambucil and Stevens-Johnson Syndrome

chlorambucil has been researched along with Stevens-Johnson Syndrome in 4 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's3 (75.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aydogdu, I1
Ozcan, C1
Harputluoglu, M1
Karincaoglu, Y1
Turhan, O1
Ozcanu, A1
Barone, C1
Cassano, A1
Astone, A1
Pietrantonio, F1
Moriconi, L1
Torino, F1
Romano, A1
Gargovich, A1
Vissian, L1
Martin, J1
Vaillaud, JC1

Other Studies

4 other studies available for chlorambucil and Stevens-Johnson Syndrome

ArticleYear
Severe adverse skin reaction to chlorambucil in a patient with chronic lymphocytic leukemia.
    Anti-cancer drugs, 1997, Volume: 8, Issue:5

    Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mal

1997
Toxic epidermal necrolysis during chlorambucil therapy in chronic lymphocytic leukaemia.
    European journal of cancer (Oxford, England : 1990), 1990, Volume: 26, Issue:11-12

    Topics: Chlorambucil; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Stevens-Johnson S

1990
Unusual reaction to chlorambucil: a case report.
    Cancer letters, 1990, Nov-05, Volume: 54, Issue:3

    Topics: Chlorambucil; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Stevens-Johnson S

1990
[Lyell's syndrome observed during immunosuppressive treatment].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1968, Volume: 75, Issue:5

    Topics: Adolescent; Chlorambucil; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Skin Diseases; St

1968