chlorambucil has been researched along with Stevens-Johnson Syndrome in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (25.00) | 18.7374 |
1990's | 3 (75.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Aydogdu, I | 1 |
Ozcan, C | 1 |
Harputluoglu, M | 1 |
Karincaoglu, Y | 1 |
Turhan, O | 1 |
Ozcanu, A | 1 |
Barone, C | 1 |
Cassano, A | 1 |
Astone, A | 1 |
Pietrantonio, F | 1 |
Moriconi, L | 1 |
Torino, F | 1 |
Romano, A | 1 |
Gargovich, A | 1 |
Vissian, L | 1 |
Martin, J | 1 |
Vaillaud, JC | 1 |
4 other studies available for chlorambucil and Stevens-Johnson Syndrome
Article | Year |
---|---|
Severe adverse skin reaction to chlorambucil in a patient with chronic lymphocytic leukemia.
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Mal | 1997 |
Toxic epidermal necrolysis during chlorambucil therapy in chronic lymphocytic leukaemia.
Topics: Chlorambucil; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Stevens-Johnson S | 1990 |
Unusual reaction to chlorambucil: a case report.
Topics: Chlorambucil; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Middle Aged; Stevens-Johnson S | 1990 |
[Lyell's syndrome observed during immunosuppressive treatment].
Topics: Adolescent; Chlorambucil; Humans; Immunosuppressive Agents; Kidney Diseases; Male; Skin Diseases; St | 1968 |