Page last updated: 2024-10-24

chlorambucil and Sezary Syndrome

chlorambucil has been researched along with Sezary Syndrome in 14 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Sezary Syndrome: A form of cutaneous T-cell lymphoma manifested by generalized exfoliative ERYTHRODERMA; PRURITUS; peripheral lymphadenopathy, and abnormal hyperchromatic mononuclear (cerebriform) cells in the skin, LYMPH NODES, and peripheral blood (Sezary cells).

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's3 (21.43)18.2507
2000's0 (0.00)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al-Niaimi, F1
Cox, NH1
Taylor, WD1
Jurkovicova, J1
Xicoy, B1
Bielsa, I1
Arellano, A1
Holmes, RC1
McGibbon, DH1
Black, MM1
Winkelmann, RK3
Diaz-Perez, JL1
Buechner, SA1
Lorent, A1
Feermans, W1
Blondeel, A1
Meerts, P1
Achten, G1
Ferme, F1
Andrieu, JM1
Flandrin, G1
Bernard, J1
Weinerman, BH1
Lu, LC1
Pineda, AA2
Marschalkó, M1
Knobler, R1
Soós, G1
Berecz, M1
Pálóczy, K1
Rácz, I1
Distelrath, K1
Neuber, K1
Blödorn-Schlicht, N1
Altenhoff, J1
Dührsen, U1
Düring, J1
Steinkraus, V1
Hamminga, L1
Hartgrink-Groeneveld, CA1
van Vloten, WA1
Harland, CC1
Balsitis, M1
Millard, LG1
McEvoy, MT1
Zelickson, BD1
Bernengo, MG1
Meregalli, M1
Jemma, C1
Lisa, F1

Other Studies

14 other studies available for chlorambucil and Sezary Syndrome

ArticleYear
Follicular hyperkeratosis as a manifestation of Sézary syndrome.
    The British journal of dermatology, 2010, Volume: 162, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Diagnosis, Differential; Facial Dermatoses; Humans;

2010
[Sustained molecular remission in an adult patient with Sézary syndrome after peripheral allogeneic stem-cell transplantation].
    Medicina clinica, 2011, Mar-19, Volume: 136, Issue:7

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Fema

2011
Mycosis fungoides: progression towards Sézary syndrome reversed with chlorambucil.
    Clinical and experimental dermatology, 1983, Volume: 8, Issue:4

    Topics: Aged; Chlorambucil; Humans; Male; Mycosis Fungoides; Sezary Syndrome

1983
The treatment of Sézary syndrome.
    Journal of the American Academy of Dermatology, 1984, Volume: 10, Issue:6

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy

1984
[Sézary syndrome: treatment with a prednisolone-chlorambucil combination].
    Dermatologica, 1982, Volume: 165, Issue:5

    Topics: Administration, Oral; Aged; Chlorambucil; Drug Therapy, Combination; Female; Humans; Prednisolone; S

1982
Sézary syndrome occurring ten years after monoclonal gammapathy treated for four years by chlorambucil.
    Leukemia research, 1981, Volume: 5, Issue:2

    Topics: Aged; Chlorambucil; Humans; Hypergammaglobulinemia; Male; Sezary Syndrome; Time Factors

1981
Sézary syndrome-an unusual case.
    Cancer, 1981, Jun-15, Volume: 47, Issue:12

    Topics: Administration, Topical; Chlorambucil; Female; Humans; Leukocyte Count; Mechlorethamine; Prednisone;

1981
Leukapheresis in the treatment of Sézary syndrome.
    Journal of the American Academy of Dermatology, 1981, Volume: 5, Issue:5

    Topics: Adult; Aged; Blood Cell Count; Chlorambucil; Drug Therapy, Combination; Female; Humans; Leukapheresi

1981
[Extracorporeal photopheresis in the therapy of Sézary syndrome].
    Orvosi hetilap, 1993, Jun-06, Volume: 134, Issue:23

    Topics: Administration, Oral; Blood Component Transfusion; Chlorambucil; Combined Modality Therapy; Humans;

1993
[Painful ischemia of the extremities with T-cell lymphoma].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:4

    Topics: Chlorambucil; Female; Foot; Hand; Humans; Ischemia; Lymphoma, T-Cell; Male; Middle Aged; Pain; Predn

1999
Sézary's syndrome: a clinical evaluation of eight patients.
    The British journal of dermatology, 1979, Volume: 100, Issue:3

    Topics: Aged; Bone Marrow; Chlorambucil; Female; Humans; Leukocyte Count; Lymph Nodes; Lymphocytes; Male; Mi

1979
Sézary-type cutaneous T-cell leukaemia. Response to Winkelmann regimen.
    Acta dermato-venereologica, 1990, Volume: 70, Issue:3

    Topics: Adult; Chlorambucil; Female; Humans; Leukemia, T-Cell; Lymphoma; Prednisolone; Prognosis; PUVA Thera

1990
Intermittent leukapheresis: an adjunct to low-dose chemotherapy for Sézary syndrome.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:1

    Topics: Chlorambucil; Combined Modality Therapy; Drug Therapy, Combination; Female; Humans; Leukapheresis; M

1989
Functional properties in Sézary cells with an unusual phenotype.
    Clinical immunology and immunopathology, 1985, Volume: 37, Issue:3

    Topics: Aged; Antibodies, Monoclonal; Chlorambucil; Dermatitis, Exfoliative; Drug Therapy, Combination; Huma

1985