chlorambucil has been researched along with Sarcoidosis, Pulmonary in 1 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Sarcoidosis, Pulmonary: Sarcoidosis affecting predominantly the lungs, the site most frequently involved and most commonly causing morbidity and mortality in sarcoidosis. Pulmonary sarcoidosis is characterized by sharply circumscribed granulomas in the alveolar, bronchial, and vascular walls, composed of tightly packed cells derived from the mononuclear phagocyte system. The clinical symptoms when present are dyspnea upon exertion, nonproductive cough, and wheezing. (Cecil Textbook of Medicine, 19th ed, p431)
| Excerpt | Relevance | Reference |
|---|---|---|
| "1) PURPOSE: To demonstrate usefulness of chlorambucil in patients with severe sarcoidosis unresponsive to, or intolerant of, corticosteroids." | 7.68 | Chlorambucil treatment of sarcoidosis. ( Israel, HL; McComb, BL, 1991) |
| "1) PURPOSE: To demonstrate usefulness of chlorambucil in patients with severe sarcoidosis unresponsive to, or intolerant of, corticosteroids." | 3.68 | Chlorambucil treatment of sarcoidosis. ( Israel, HL; McComb, BL, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Israel, HL | 1 |
| McComb, BL | 1 |
1 other study available for chlorambucil and Sarcoidosis, Pulmonary
| Article | Year |
|---|---|
Chlorambucil treatment of sarcoidosis.
Topics: Adult; Chlorambucil; Female; Humans; Lung; Male; Middle Aged; Radiography; Sarcoidosis; Sarcoidosis, | 1991 |