chlorambucil has been researched along with Rheumatism in 17 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Methotrexate, azathioprine, mycophenolate mofetil, cyclosporin cyclophosphamide, chlorambucil, and other related drugs have potential benefits in the treatment of severe and/or recalcitrant rheumatic skin diseases." | 4.81 | Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders. ( Callen, JP, 2001) |
| "Azathioprine is a valuable alternative to slow-acting antirheumatic drugs in older patients with rheumatoid arthritis." | 2.38 | Azathioprine, cyclophosphamide and chlorambucil. ( Bacon, PA; Luqmani, RA; Palmer, RG, 1990) |
| "Chlorambucil alone was given in 14 treatment periods, cyclophosphamide alone in six, and both alternately in two." | 1.27 | Alkylating cytostatic treatment in renal amyloidosis secondary to rheumatic disease. ( Berglund, K; Keller, C; Thysell, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (41.18) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 2 (11.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berglund, K | 3 |
| Thysell, H | 3 |
| Keller, C | 2 |
| Steinberg, AD | 1 |
| Bermas, BL | 1 |
| Hill, JA | 1 |
| Ramsey-Goldman, R | 1 |
| Schilling, E | 1 |
| McCarthy, CJ | 1 |
| Sheldon, S | 1 |
| Ross, CW | 1 |
| McCune, WJ | 2 |
| Callen, JP | 1 |
| Ortiz-Santamaría, V | 1 |
| Olivé, A | 1 |
| Valls-Roc, M | 1 |
| Tena, X | 1 |
| Friedman, AW | 1 |
| Luqmani, RA | 1 |
| Palmer, RG | 1 |
| Bacon, PA | 1 |
| Clements, PJ | 1 |
| Davis, J | 1 |
| Deshayes, P | 1 |
| Piguet, H | 1 |
| Renier, JC | 1 |
| Delaporte, J | 1 |
| Laumonier, R | 1 |
| Geffroy, Y | 1 |
| Mayr, E | 1 |
| Kahn, MF | 2 |
| de Sèze, S | 1 |
| Six, B | 1 |
| Krampac, I | 1 |
8 reviews available for chlorambucil and Rheumatism
| Article | Year |
|---|---|
Effects of immunosuppressive drugs during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Azathioprine; Chlorambucil; Cyclophos | 1995 |
Immunosuppressive drug use during pregnancy.
Topics: Adrenal Cortex Hormones; Animals; Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Female | 1997 |
Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders.
Topics: Adult; Alkylating Agents; Antimetabolites; Azathioprine; Child; Chlorambucil; Cladribine; Cyclophosp | 2001 |
Immunosuppressive drug therapy for rheumatic disease.
Topics: Azathioprine; Chlorambucil; Cyclosporine; Humans; Immunosuppressive Agents; Rheumatic Diseases | 1992 |
Azathioprine, cyclophosphamide and chlorambucil.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Connective Tissue Diseases; Cyclophosphamide; Hum | 1990 |
Cytotoxic drugs: their clinical application to the rheumatic diseases.
Topics: Arthritis; Arthritis, Rheumatoid; Azathioprine; Behcet Syndrome; Bone Marrow; Cell Division; Chemica | 1986 |
[Antirheumatics. 40].
Topics: Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Chlorambucil; Female; Humans; Immunosu | 1969 |
[The immunodepressive agents. II. Immunodepressive agents in rheumatic diseases].
Topics: Azathioprine; Chlorambucil; Humans; Immunosuppressive Agents; Rheumatic Diseases; Thiotepa | 1967 |
9 other studies available for chlorambucil and Rheumatism
| Article | Year |
|---|---|
Results, principles and pitfalls in the management of renal AA-amyloidosis; a 10-21 year followup of 16 patients with rheumatic disease treated with alkylating cytostatics.
Topics: Albumins; Amyloidosis; Antineoplastic Agents; C-Peptide; Chlorambucil; Creatinine; Cyclophosphamide; | 1993 |
Chlorambucil in the treatment of patients with immune-mediated rheumatic diseases.
Topics: Chlorambucil; Humans; Immunosuppressive Agents; Rheumatic Diseases | 1993 |
Renal amyloidosis secondary to chronic rheumatic inflammatory disease.
Topics: Amyloidosis; Antineoplastic Agents, Alkylating; Chlorambucil; Chronic Disease; Humans; Kidney Diseas | 1996 |
Cytogenetic abnormalities and therapy-related myelodysplastic syndromes in rheumatic disease.
Topics: Adult; Aged; Alkylating Agents; Chlorambucil; Chromosome Aberrations; Chromosome Disorders; Chromoso | 1998 |
Treatment of AA amyloid with chlorambucil.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyloidosis; Child; Chlorambucil; Creatinine; Female; Hu | 2002 |
Alkylating cytostatic treatment in renal amyloidosis secondary to rheumatic disease.
Topics: Adult; Amyloidosis; Chlorambucil; Cyclophosphamide; Female; Humans; Kidney; Kidney Diseases; Male; R | 1987 |
[Waldenström's disease. Rheumatologic manifestations].
Topics: Aged; Blood Coagulation Disorders; Chlorambucil; Eye Manifestations; Female; Humans; Joint Diseases; | 1968 |
[Immunosuppressive therapy in inflammatory rheumatism].
Topics: Adult; Arthritis, Rheumatoid; Chlorambucil; Female; Humans; Immunosuppressive Agents; Male; Rheumati | 1969 |
[Positive and negative effects of cytostatic therapy in rheumatic patients].
Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Cyclophosphamide; Humans; Mercaptopurine; Methotr | 1970 |