chlorambucil has been researched along with Retinal Detachment in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Retinal Detachment: Separation of the inner layers of the retina (neural retina) from the pigment epithelium. Retinal detachment occurs more commonly in men than in women, in eyes with degenerative myopia, in aging and in aphakia. It may occur after an uncomplicated cataract extraction, but it is seen more often if vitreous humor has been lost during surgery. (Dorland, 27th ed; Newell, Ophthalmology: Principles and Concepts, 7th ed, p310-12).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chlorambucil therapy was begun at 2 mg daily, increased by 2 mg per day each week to the maximum of 8 to 12 mg per day." | 1.29 | Chlorambucil therapy in sympathetic ophthalmia. ( Liu, JH; Yang, CS, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cunningham, ET | 1 |
| Demetrius, R | 1 |
| Frieden, IJ | 1 |
| Emery, HM | 1 |
| Irvine, AR | 1 |
| Good, WV | 1 |
| Yang, CS | 1 |
| Liu, JH | 1 |
| Murphy, JA | 1 |
| Pitts, JF | 1 |
| Dudgeon, J | 1 |
| Hogg, RB | 1 |
| Harnett, AN | 1 |
| Bonnet, M | 1 |
1 review available for chlorambucil and Retinal Detachment
| Article | Year |
|---|---|
[Immunodepressors in ophthalmology].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Antibiotics, Antineoplastic; Antilymphocyte Se | 1971 |
3 other studies available for chlorambucil and Retinal Detachment
| Article | Year |
|---|---|
Vogt-Koyanagi-Harada syndrome in a 4-year old child.
Topics: Alopecia; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Blindness; Child, Preschool; | 1995 |
Chlorambucil therapy in sympathetic ophthalmia.
Topics: Adult; Cataract; Cataract Extraction; Chlorambucil; Eye Foreign Bodies; Eye Injuries, Penetrating; F | 1995 |
Retinal detachments due to chronic lymphocytic leukaemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Humans; Leu | 1991 |