chlorambucil has been researched along with Pyoderma Gangrenosum in 2 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Pyoderma Gangrenosum: An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burruss, JB | 1 |
| Farmer, ER | 1 |
| Callen, JP | 1 |
| Resnik, BI | 1 |
| Rendon, M | 1 |
| Kerdel, FA | 1 |
1 trial available for chlorambucil and Pyoderma Gangrenosum
| Article | Year |
|---|---|
Chlorambucil is an effective corticosteroid-sparing agent for recalcitrant pyoderma gangrenosum.
Topics: Adult; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Humans; Male; Middle Aged; Pyoderma | 1996 |
1 other study available for chlorambucil and Pyoderma Gangrenosum
| Article | Year |
|---|---|
Successful treatment of aggressive pyoderma gangrenosum with pulse steroids and chlorambucil.
Topics: Administration, Oral; Aged; Aged, 80 and over; Chlorambucil; Drug Therapy, Combination; Female; Huma | 1992 |