chlorambucil has been researched along with Purpura, Thrombopenic in 10 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 67-year-old man with Waldenström's macroglobulinemia had a relapse of chronic idiopathic thrombocytopenic purpura (ITP), which had been refractory to corticosteroids, splenectomy, vinca alkaloids, and high-dose intravenous gamma-globulin therapy." | 2.39 | Role of plasmapheresis in thrombocytopenic purpura associated with Waldenström's macroglobulinemia. ( Moore, SB; Patel, TC; Pineda, AA; Witzig, TE, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Patel, TC | 1 |
| Moore, SB | 1 |
| Pineda, AA | 1 |
| Witzig, TE | 1 |
| Stacher, A | 1 |
| Delespesse, G | 1 |
| Kennes, B | 1 |
| Duchateau, J | 1 |
| Dacie, JV | 1 |
| Klener, P | 1 |
| Stojcevski, T | 1 |
| Nedelkoski, J | 1 |
| Kostovska, S | 1 |
| Berceanu, S | 1 |
| Sighetea, E | 1 |
| Gociu, M | 1 |
| Ghetie, I | 1 |
| Stoica, GH | 1 |
| Voiosu, R | 1 |
| Schumacher, K | 1 |
| Gross, R | 1 |
| Cattan, D | 1 |
| Caen, J | 1 |
| Fernandez, Y | 1 |
| Izard, J | 1 |
| Leclere, H | 1 |
| Tanguy, A | 1 |
| Lemenager, J | 1 |
| Lewis, FB | 1 |
| Schwartz, RS | 1 |
| Dameshek, W | 1 |
2 reviews available for chlorambucil and Purpura, Thrombopenic
| Article | Year |
|---|---|
Role of plasmapheresis in thrombocytopenic purpura associated with Waldenström's macroglobulinemia.
Topics: Aged; Chlorambucil; Humans; Male; Plasmapheresis; Prednisone; Purpura, Thrombocytopenic; Waldenstrom | 1996 |
[Auto-immune diseases and immunodepressive therapy. II. Current clinical indications].
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Arteritis; Autoimmune | 1974 |
1 trial available for chlorambucil and Purpura, Thrombopenic
| Article | Year |
|---|---|
Vinca alkaloids. Experimental and clinical trials.
Topics: Animals; Cell Movement; Chlorambucil; Choriocarcinoma; Female; Hematopoiesis; Hematopoietic Stem Cel | 1974 |
7 other studies available for chlorambucil and Purpura, Thrombopenic
| Article | Year |
|---|---|
[Immunosuppressive therapy in hematology].
Topics: Adrenal Cortex Hormones; Adult; Anemia, Aplastic; Anemia, Hemolytic, Autoimmune; Anemia, Myelophthis | 1972 |
Clinical immunology and the physician. Blood.
Topics: Adrenocorticotropic Hormone; Anemia, Hemolytic, Autoimmune; Anemia, Macrocytic; Blood Transfusion; C | 1974 |
[Immunosuppressive cytostatic therapy in idiopathic thrombocytopenic purpura].
Topics: Adolescent; Adult; Aged; Azathioprine; Chlorambucil; Female; Humans; Mercaptopurine; Middle Aged; Pu | 1973 |
Peculiar forms of monoclonal gammapathies.
Topics: Adrenal Cortex Hormones; Antigen-Antibody Complex; Blood Protein Disorders; Chlorambucil; Cryoglobul | 1973 |
[Immunosuppressive treatment of autoantibody anemia and idiopathic thrombocytopenic purpura].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antibodies; Autoantibodie | 1972 |
[Chronic thrombopenic purpura. Hyperthyroidism, pretibial myxedema and L.A.T.S].
Topics: Autoimmune Diseases; Azathioprine; Chlorambucil; Chronic Disease; Exophthalmos; Female; Glucocortico | 1970 |
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Chlorambucil; Humans; Leukemia, Lymphoid; Lymphoma, Non- | 1966 |