Page last updated: 2024-10-24

chlorambucil and Proteinuria

chlorambucil has been researched along with Proteinuria in 56 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Proteinuria: The presence of proteins in the urine, an indicator of KIDNEY DISEASES.

Research Excerpts

ExcerptRelevanceReference
" The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy."7.67Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984)
"The therapy of nephrotic syndrome in focal segmental glomerulosclerosis (FSGS) is still a matter of controversy."6.71Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis. ( Braun, N; Fünfstück, R; Grabensee, B; Heering, P; Ivens, K; Keller, F; Krämer, BK; Müllejans, R; Risler, T; Schollmeyer, P; Zäuner, I, 2004)
" To explore this uncertainty, a meta-analysis of controlled trials of treatment with cyclophosphamide or chlorambucil was performed in patients with idiopathic membranous nephropathy and nephrotic-range proteinuria."6.17Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials. ( Berns, JS; Goldfarb, S; Imperiale, TF, 1995)
"This observational study aimed to evaluate the results of treatment with low-dose chlorambucil in combination with corticosteroids in patients with idiopathic membranous nephropathy (iMGN) and nephrotic syndrome."5.14Efficacy and safety of low-dose chlorambucil in nephrotic patients with idiopathic membranous nephropathy. ( Idasiak-Piechocka, I; Oko, A; Skrobańska, B; Łochyńska-Bielecka, K, 2009)
" It was found that RTX did not significantly improve serum albumin levels and e-GFR when compared with the control group (including cyclosporine and cyclophosphamide, chlorambucil, prednisone, non-immunosuppressive anti-proteinuria treatment), serum albumin levels (OR = 0."5.05Efficacy and safety of rituximab in the treatment of membranous nephropathy: A systematic review and meta-analysis. ( Gong, S; Li, J; Lu, W; Luo, H; Wang, Y, 2020)
"Sixty-seven adults with idiopathic membranous nephropathy and the nephrotic syndrome were randomly assigned to symptomatic treatment only or to a six-month course of methylprednisolone alternated with chlorambucil every other month."5.05Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy. ( Cagnoli, L; Grassi, C; Imbasciati, E; Limido, D; Pasquali, S; Passerini, P; Ponticelli, C; Pozzi, C; Volpini, T; Zucchelli, P, 1984)
" Renal biopsy confirmed the diagnosis of amyloidosis, and chlorambucil was initiated, with general improvement of the disease and reduction of proteinuria."3.73Renal amyloidosis: an uncommon complication of juvenile idiopathic arthritis. ( Correia, AJ; Duarte, C; Gomes, C; Salgado, M, 2006)
"Twenty-one patients with membranous nephropathy, heavy proteinuria and progressive renal failure were treated with alternating monthly cycles of corticosteroids and chlorambucil for six months."3.69Prednisolone and chlorambucil therapy for idiopathic membranous nephropathy with progressive renal failure. ( Boulton-Jones, JM; Geddes, CG; Warwick, GL, 1994)
" The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy."3.67Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984)
"The therapy of nephrotic syndrome in focal segmental glomerulosclerosis (FSGS) is still a matter of controversy."2.71Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis. ( Braun, N; Fünfstück, R; Grabensee, B; Heering, P; Ivens, K; Keller, F; Krämer, BK; Müllejans, R; Risler, T; Schollmeyer, P; Zäuner, I, 2004)
"Patients with biopsy-proven membranous nephropathy and with a nephrotic syndrome were randomized to be given methylprednisolone (1 g intravenously for 3 consecutive days followed by oral methylprednisolone, 0."2.69A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy. ( Altieri, P; Antonucci, F; Bellazzi, R; Cesana, B; Dugo, M; Farina, M; Grassi, C; Lupo, A; Melis, P; Minari, M; Pasquali, S; Passerini, P; Pedrini, L; Piccoli, G; Pisano, G; Ponticelli, C; Pozzi, C; Roccatello, D; Sasdelli, M; Scalia, A; Scolari, F; Segagni, S; Valzorio, B, 1998)
"Those with nephrotic syndrome are usually treated with steroids initially and often followed by alkylating agents (cyclophosphamide or chlorambucil)."2.46Membranous nephropathy in children: clinical presentation and therapeutic approach. ( Menon, S; Valentini, RP, 2010)
"Persistent hyperlipidemia increases the risk of cardiovascular diseases."2.42[Membranous nephropathy]. ( Godin, M; Legallicier, B; Passos, EM, 2003)
"Patients with nephrotic syndrome are in a constant state of flux with respect to fluid status, organ function, and critical protein balance."2.38Pharmacologic management of adult idiopathic nephrotic syndrome. ( Alaniz, C; Brosius, FC; Palmieri, J, 1993)
"Children with systemic lupus erythematosus and nephritis may benefit from the addition of cytotoxic agents to their corticosteroid regime, although the indications for this are not clear, and controlled evidence is lacking."2.36Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children. ( Cameron, JS, 1979)
"Idiopathic Idiopathic membranous nephropathy (iMN) is an immune-complex mediated renal disease which is usually associated with the nephrotic syndrome (NS)."1.56Idiopathic Membranous Nephropathy and Treatment Related Complications. ( Dzemidzic, J; Haskovic, D; Muslimovic, A; Serdarevic, N; Uncanin, S, 2020)
"Although nondiabetic nephropathies are common among type 2 diabetic patients, very few cases of minimal change nephrotic syndrome have been reported in diabetic patients."1.32[Relapsing nephrotic syndrome in a diabetic patient with minimal change]. ( Espejo, B; García Donaire, JA; Gutiérrez Martínez, E; Manzanera, MI; Praga, M; Valentín, MO, 2004)
" No untoward effect from drugs sufficient to alter the dosage used was recorded."1.30Clinical features and treatment outcome of idiopathic membranous nephropathy in Chinese patients. ( Chan, TM; Cheng, IK; Lai, KN; Tang, S, 1999)
"Proteinuria was reduced in all eight, from a mean (SD) of 15."1.27Prednisolone and chlorambucil treatment in idiopathic membranous nephropathy with deteriorating renal function. ( Evans, DJ; Maidment, CG; Mathieson, PW; Rees, AJ; Turner, AN, 1988)
"The renal survival of 53 MPGN patients treated on a long-term basis by non-steroid anti-inflammatory drugs (NSAID) was compared to that of untreated MPGN patients previously reported in the literature."1.27Renal survival in membranoproliferative glomerulonephritis (MPGN): role of long-term treatment with non-steroid anti-inflammatory drugs (NSAID). ( Belghiti, D; Lagrue, G; Laurent, J, 1988)
"Proteinuria is the most frequent sign in the early stage of the amyloidosis."1.26[Amyloidosis-a dreaded complication of juvenile chronic arthritis (JCA). (author's transl)]. ( Michels, H; Renaud, M; Renz, K; Schuchmann, L, 1981)

Research

Studies (56)

TimeframeStudies, this research(%)All Research%
pre-199035 (62.50)18.7374
1990's9 (16.07)18.2507
2000's8 (14.29)29.6817
2010's2 (3.57)24.3611
2020's2 (3.57)2.80

Authors

AuthorsStudies
Lu, W1
Gong, S1
Li, J1
Luo, H1
Wang, Y1
Uncanin, S1
Dzemidzic, J1
Serdarevic, N1
Muslimovic, A1
Haskovic, D1
Schmidt, S1
Sears, M1
Crawford, S1
Cicci, C1
Diskin, CJ1
Idasiak-Piechocka, I1
Oko, A1
Łochyńska-Bielecka, K1
Skrobańska, B1
Menon, S1
Valentini, RP1
Heering, P1
Braun, N1
Müllejans, R1
Ivens, K1
Zäuner, I1
Fünfstück, R1
Keller, F1
Krämer, BK1
Schollmeyer, P1
Risler, T1
Grabensee, B1
Passos, EM1
Legallicier, B1
Godin, M1
García Donaire, JA1
Manzanera, MI1
Valentín, MO1
Espejo, B1
Gutiérrez Martínez, E1
Praga, M2
Hebert, LA1
Rovin, BH1
Agarwal, AK1
Spetie, DN1
Duarte, C1
Gomes, C1
Correia, AJ1
Salgado, M1
Ponticelli, C6
Zucchelli, P4
Imbasciati, E2
Cagnoli, L3
Pozzi, C4
Passerini, P4
Grassi, C3
Limido, D1
Pasquali, S3
Volpini, T1
Abuelo, JG1
Esparza, AR1
Garella, S1
Schuchmann, L1
Michels, H1
Renaud, M1
Renz, K1
Imperiale, TF1
Goldfarb, S1
Berns, JS1
Como, G1
Viganò, E1
Melis, P2
Altieri, P2
Winearls, CG1
Sanderson, F1
Warwick, GL1
Geddes, CG1
Boulton-Jones, JM1
Alaniz, C1
Brosius, FC1
Palmieri, J1
Scolari, F1
Roccatello, D1
Cesana, B2
Valzorio, B1
Sasdelli, M1
Piccoli, G1
Lupo, A1
Segagni, S1
Antonucci, F1
Dugo, M1
Minari, M1
Scalia, A1
Pedrini, L1
Pisano, G1
Farina, M1
Bellazzi, R1
Moroni, G1
Maccario, M1
Banfi, G1
Quaglini, S1
Tang, S1
Chan, TM1
Cheng, IK1
Lai, KN1
Torres, A1
Domínguez-Gil, B1
Carreño, A1
Hernández, E1
Morales, E1
Segura, J1
González, E1
Ortiz-Santamaría, V1
Olivé, A1
Valls-Roc, M1
Tena, X1
Cameron, JS3
Lagrue, G4
Bernard, D1
Bariety, J3
Druet, P1
Guenel, J1
Epstein, WV1
Brandis, M1
Krause, PH1
Hünermund, G1
Bahlmann, J1
Niaudet, P1
Redaelli, B1
Mathieson, PW1
Turner, AN1
Maidment, CG1
Evans, DJ1
Rees, AJ1
Aroldi, A1
Beltrandi, E1
Laurent, J1
Belghiti, D1
Boulton-Jones, M1
Robinson, R1
Ogg, C1
Mukherjee, AP1
Grupe, WE1
Rossipal, E2
Falk, W1
Zangger, J1
Dathan, JR1
Heyworth, MF1
MacIver, AG1
Deshayes, P1
Piguet, H1
Renier, JC1
Delaporte, J1
Laumonier, R1
Geffroy, Y1
Hooft, C1
van Acker, KJ1
Zech, P1
Richard, P1
Blanc-Brunat, N1
Labeeuw, M1
Colon, S1
Pozet, N1
Dupont, E1
Fries, D1
Traeger, J1
Habib, R1
Levy, M1
Lokich, JJ1
Galvanek, EG1
Moloney, WC1
Linshaw, MA1
Gruskin, AB1
Orlowski, T1
Gradowska, L1
Lao, M1
Rancewicz, Z1
Rowinska, D1
Snaith, ML1
Holt, JM1
Oliver, DO1
Stephenson, A1
Forssman, O1
Björkman, G1
Hollender, A1
Englund, NE1
Makker, SP1
Heymann, W1
Samarcq, P1
Fritel, D1
Milliez, P1
Poth, JL1
Sharp, GS1
Schrier, SL1
Brodovsky, HS1
Samuels, ML1
Migliore, PJ1
Howe, CD1
Lévèque, B1
Debauchez, C1
Deflandre, L1
Marie, J1
Brass, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Clinical Study of Rituximab or Cyclophosphamide Combined With Steroids in the Treatment of Idiopathic Membranous Nephropathy[NCT05514015]Phase 472 participants (Anticipated)Interventional2022-08-25Not yet recruiting
Random, Open, Control and Monocentric Clinical Research on Tacrolimus Monotherapy for Idiopathic Membranous Nephropathy (IMN)[NCT03549663]108 participants (Anticipated)Interventional2018-07-04Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for chlorambucil and Proteinuria

ArticleYear
Efficacy and safety of rituximab in the treatment of membranous nephropathy: A systematic review and meta-analysis.
    Medicine, 2020, Volume: 99, Issue:16

    Topics: Adult; Aged; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Hormonal; Antineoplastic Agen

2020
Membranous nephropathy in children: clinical presentation and therapeutic approach.
    Pediatric nephrology (Berlin, Germany), 2010, Volume: 25, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biopsy; Child; Chlorambucil; Cycl

2010
[Membranous nephropathy].
    La Revue du praticien, 2003, Nov-30, Volume: 53, Issue:18

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Basement Membrane; Child; Child, Preschool; Chlorambuci

2003
Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:8

    Topics: Chlorambucil; Cyclophosphamide; Glomerulonephritis, Membranous; Humans; Kidney; Nephrotic Syndrome;

1995
Pharmacologic management of adult idiopathic nephrotic syndrome.
    Clinical pharmacy, 1993, Volume: 12, Issue:6

    Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclosporine; Drug Therapy, Combination; Edema; Glomeruloneph

1993
Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children.
    Paediatrician, 1979, Volume: 8, Issue:5-6

    Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive A

1979
[Prognosis of the idiopathic nephrotic syndrome in children].
    Verhandelingen - Koninklijke Vlaamse Academie voor Geneeskunde van Belgie, 1974, Volume: 36, Issue:2

    Topics: Adrenocorticotropic Hormone; Biopsy; Blood Proteins; Chlorambucil; Cyclophosphamide; Female; Humans;

1974
Management of the nephrotic syndrome.
    Clinical pediatrics, 1974, Volume: 13, Issue:1

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos

1974
Immunosuppressant agents in the treatment of glomerulonephritis. 2. Cytotoxic drugs.
    Journal of the Royal College of Physicians of London, 1971, Volume: 5, Issue:4

    Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antilymphocyte Serum; Antineoplastic Agents; Azath

1971

Trials

11 trials available for chlorambucil and Proteinuria

ArticleYear
Efficacy and safety of low-dose chlorambucil in nephrotic patients with idiopathic membranous nephropathy.
    Kidney & blood pressure research, 2009, Volume: 32, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Follow-Up

2009
Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2004, Volume: 43, Issue:1

    Topics: Adult; Aged; Alkylating Agents; Biopsy; Chlorambucil; Cyclosporine; Drug Therapy, Combination; Femal

2004
Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy.
    The New England journal of medicine, 1984, Apr-12, Volume: 310, Issue:15

    Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Creatinine; Drug Administration Schedule; Femal

1984
Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 5, Issue:8

    Topics: Chlorambucil; Cyclophosphamide; Glomerulonephritis, Membranous; Humans; Kidney; Nephrotic Syndrome;

1995
Idiopathic membranous nephropathy in the elderly.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1993, Volume: 8, Issue:12

    Topics: Adolescent; Adult; Aged; Chlorambucil; Creatinine; Drug Therapy, Combination; Female; Glomerulonephr

1993
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu

1998
[Treatment with chlorambucil and azathioprine in primary glomerulonephritis. Results of a "controlled" study].
    Journal d'urologie et de nephrologie, 1975, Volume: 81, Issue:9

    Topics: Anti-Bacterial Agents; Antihypertensive Agents; Azathioprine; Chlorambucil; Clinical Trials as Topic

1975
A randomized trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy.
    The New England journal of medicine, 1989, Jan-05, Volume: 320, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Chlorambucil; Clinical Trials as Topic; Creatinine; D

1989
Prognostic value of T lymphocyte subset ratio in idiopathic membranous nephropathy.
    American journal of nephrology, 1988, Volume: 8, Issue:1

    Topics: Adult; Antibodies, Monoclonal; Chlorambucil; Humans; Methylprednisolone; Middle Aged; Nephrotic Synd

1988
The advantages of immunosuppressive therapy in renal disease.
    Annales de medecine interne, 1988, Volume: 139, Issue:2

    Topics: Chlorambucil; Clinical Trials as Topic; Follow-Up Studies; Glomerulonephritis; Humans; Immunosuppres

1988
Management of the nephrotic syndrome.
    Clinical pediatrics, 1974, Volume: 13, Issue:1

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos

1974

Other Studies

38 other studies available for chlorambucil and Proteinuria

ArticleYear
Idiopathic Membranous Nephropathy and Treatment Related Complications.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2020, Volume: 74, Issue:3

    Topics: Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents, Alkylating; Chlorambucil; Drug Ther

2020
Membranous Glomerulopathy in Hypogammaglobulinemia.
    The American journal of the medical sciences, 2017, Volume: 353, Issue:3

    Topics: Agammaglobulinemia; Chlorambucil; gamma-Globulins; Glomerulonephritis, Membranous; Humans; Infusions

2017
[Relapsing nephrotic syndrome in a diabetic patient with minimal change].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24, Issue:2

    Topics: Chlorambucil; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diagnosis, Differential; Drug Thera

2004
Cyclophosphamide or chlorambucil therapy is indicated in idiopathic membranous nephropathy with strong risk factors for progression.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2005, Volume: 45, Issue:4

    Topics: Chlorambucil; Creatinine; Cyclophosphamide; Disease Progression; Drug Therapy, Combination; Glomerul

2005
Renal amyloidosis: an uncommon complication of juvenile idiopathic arthritis.
    Clinical rheumatology, 2006, Volume: 25, Issue:4

    Topics: Age of Onset; Amyloidosis; Arthritis, Juvenile; Child; Chlorambucil; Female; Humans; Kidney; Protein

2006
Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil.
    Archives of internal medicine, 1984, Volume: 144, Issue:12

    Topics: Adult; Chlorambucil; Female; Glomerulonephritis; Humans; Lupus Erythematosus, Systemic; Nephrotic Sy

1984
[Amyloidosis-a dreaded complication of juvenile chronic arthritis (JCA). (author's transl)].
    Klinische Padiatrie, 1981, Volume: 193, Issue:2

    Topics: Adolescent; Amyloidosis; Arthritis, Juvenile; Child; Child, Preschool; Chlorambucil; Chronic Disease

1981
Treatment of aggressive idiopathic membranous glomerulonephritis.
    The Quarterly journal of medicine, 1994, Volume: 87, Issue:4

    Topics: Chlorambucil; Glomerulonephritis, Membranous; Humans; Kidney Failure, Chronic; Prognosis; Proteinuri

1994
Prednisolone and chlorambucil therapy for idiopathic membranous nephropathy with progressive renal failure.
    The Quarterly journal of medicine, 1994, Volume: 87, Issue:4

    Topics: Adult; Aged; Chlorambucil; Cohort Studies; Female; Glomerulonephritis, Membranous; Humans; Kidney; K

1994
Treatment of membranous lupus nephritis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1998, Volume: 31, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chlorambucil; Drug Evaluation; Drug Therapy, Combination

1998
Clinical features and treatment outcome of idiopathic membranous nephropathy in Chinese patients.
    QJM : monthly journal of the Association of Physicians, 1999, Volume: 92, Issue:7

    Topics: Aged; Antihypertensive Agents; Chlorambucil; Creatinine; Cyclophosphamide; Drug Therapy, Combination

1999
Conservative versus immunosuppressive treatment of patients with idiopathic membranous nephropathy.
    Kidney international, 2002, Volume: 61, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Creatinine;

2002
Treatment of AA amyloid with chlorambucil.
    Rheumatology (Oxford, England), 2002, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amyloidosis; Child; Chlorambucil; Creatinine; Female; Hu

2002
Specificity of SLE serum antibody for single-stranded and double-stranded DNA configuration.
    The Journal of rheumatology, 1975, Volume: 2, Issue:2

    Topics: Adolescent; Ammonium Sulfate; Antibody Specificity; Arthritis, Rheumatoid; Chemical Precipitation; C

1975
[Rapidly progressive glomerulonephritis in a child. Clinical and histological observation over 3 1/2 years (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1976, Volume: 124, Issue:2

    Topics: Acute Disease; Anuria; Biopsy, Needle; Child; Chlorambucil; Glomerular Filtration Rate; Glomerulonep

1976
How to manage a child with steroid-responsive nephrotic syndrome when dose of prednisolone is reduced or when placed on high-dose alternate day steroids.
    Pediatric nephrology (Berlin, Germany), 1992, Volume: 6, Issue:6

    Topics: Child, Preschool; Chlorambucil; Cyclophosphamide; Female; Humans; Nephrotic Syndrome; Prednisolone;

1992
Prednisolone and chlorambucil treatment in idiopathic membranous nephropathy with deteriorating renal function.
    Lancet (London, England), 1988, Oct-15, Volume: 2, Issue:8616

    Topics: Adult; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Female; Follow-Up Studies; Glome

1988
Renal survival in membranoproliferative glomerulonephritis (MPGN): role of long-term treatment with non-steroid anti-inflammatory drugs (NSAID).
    International urology and nephrology, 1988, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Chlorambucil; Creati

1988
Treatment of lupus nephritis with cyclophosphamide.
    Lancet (London, England), 1970, Oct-24, Volume: 2, Issue:7678

    Topics: Adolescent; Adult; Age Factors; Azathioprine; Biopsy; Chlorambucil; Cortisone; Cyclophosphamide; Fem

1970
Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults.
    Lancet (London, England), 1971, Dec-18, Volume: 2, Issue:7738

    Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Cholesterol; Creatinine; Cyclophosphamide; Female; Gl

1971
Chlorambucil in steroid-dependent nephrotic syndrome.
    The Journal of pediatrics, 1973, Volume: 82, Issue:4

    Topics: Adolescent; Beta-Globulins; Blood Pressure; Child; Child, Preschool; Chlorambucil; Drug Synergism; F

1973
[Atypical measles with giant cell pneumonia under treatment with chlorambucil (author's transl)].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1972, Volume: 56

    Topics: Child, Preschool; Chlorambucil; Female; Humans; Immunologic Deficiency Syndromes; Measles; Nephrotic

1972
Nephrotic syndrome in chronic lymphocytic leukaemia.
    British medical journal, 1974, Sep-14, Volume: 3, Issue:5932

    Topics: Aged; Basement Membrane; Biopsy; Blood Proteins; Bone Marrow; Chlorambucil; Complement System Protei

1974
[Waldenström's disease. Rheumatologic manifestations].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, Apr-08, Volume: 44, Issue:17

    Topics: Aged; Blood Coagulation Disorders; Chlorambucil; Eye Manifestations; Female; Humans; Joint Diseases;

1968
[Course of nephropathy in systemic lupus erythematosus . Influence of the treatment on clinical symptoms, renal function and histology].
    Journal d'urologie et de nephrologie, 1972, Volume: 78, Issue:12

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antimalarials; Azathioprine; Biopsy; Chlorambucil;

1972
[Nephropathies of rheumatoid purpura in children. Clinical and anatomical study of 60 cases].
    Archives francaises de pediatrie, 1972, Volume: 29, Issue:3

    Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Diagnosis, Differential; Female; Fluorescent Anti

1972
Nephrosis of Hodgkin disease. An immune complex-induced lesion.
    Archives of internal medicine, 1973, Volume: 132, Issue:4

    Topics: Antigen-Antibody Complex; Basement Membrane; Biopsy; Blood Urea Nitrogen; Body Weight; Capillaries;

1973
[Treatment of chronic glomerulopathy].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1972, Nov-15, Volume: 27, Issue:22

    Topics: Anti-Inflammatory Agents; Azathioprine; Biopsy; Chlorambucil; Chronic Disease; Creatine; Cyclophosph

1972
Successful treatment of patients with systemic lupus erythematosus, including nephritis, using chlorambucil.
    Annals of the rheumatic diseases, 1973, Volume: 32, Issue:3

    Topics: Chlorambucil; Female; Humans; Lupus Erythematosus, Systemic; Nephritis; Proteinuria

1973
IgM-producing lymphocytes in peripheral nerve in a patient with benign monoclonal gammopathy.
    Scandinavian journal of haematology, 1973, Volume: 11, Issue:4

    Topics: Adult; Biopsy; Chlorambucil; Electrophoresis, Paper; Humans; Hypergammaglobulinemia; Immunoelectroph

1973
The idiopathic nephrotic syndrome of childhood. A clinical reevaluation of 148 cases.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:6

    Topics: Adolescent; Antistreptolysin; Azathioprine; Bacteriuria; Blood Urea Nitrogen; Child; Child, Preschoo

1974
[Recovery of normal ultrastructure in 2 cases of primary glomerulonephritis with diffuse extra-membranous deposits].
    La Presse medicale, 1968, Nov-27, Volume: 76, Issue:46

    Topics: Adult; Basement Membrane; Biopsy; Chlorambucil; Female; Glomerulonephritis; Glucocorticoids; Hematur

1968
[Prognosis of the idiopathic nephrotic syndrome in childhood by means of plasma protein clearance].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1969, Volume: 50, Issue:5

    Topics: Age Factors; Azathioprine; Blood Proteins; Child; Child, Preschool; Chlorambucil; Cyclophosphamide;

1969
[Correlations between the histological changes and results of treatment with corticoids and immunosuppressive agents in primary glomerulonephritis].
    Minerva medica, 1970, Jul-11, Volume: 61, Issue:55

    Topics: Adrenal Cortex Hormones; Alkylating Agents; Azathioprine; Chlorambucil; Glomerulonephritis; Humans;

1970
Cold agglutinin disease and the nephrotic syndrome.
    JAMA, 1970, Mar-23, Volume: 211, Issue:12

    Topics: Aged; Anemia, Hemolytic; Autopsy; Bone Marrow; Chlorambucil; Coombs Test; Cryoglobulins; Female; Hum

1970
Chronic lymphocytic leukemia, Hodgkin's disease, and the nephrotic syndrome.
    Archives of internal medicine, 1968, Volume: 121, Issue:1

    Topics: Blood Protein Electrophoresis; Chlorambucil; Cobalt Isotopes; Electrophoresis; Female; Hodgkin Disea

1968
[Chlorambucil in the treatment of idiopathic nephrotic syndrome without glomrular lesions in childhood. Apropos of 30 cases].
    Annales de pediatrie, 1969, Jan-02, Volume: 16, Issue:1

    Topics: Adolescent; Anemia; Biopsy; Child; Child, Preschool; Chlorambucil; Female; Glucocorticoids; Humans;

1969
[Therapeutic possibilities in chronic glomerulonephritis].
    Munchener medizinische Wochenschrift (1950), 1969, Aug-29, Volume: 111, Issue:35

    Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Chronic Disease; Glomerulonephritis; Humans; Immunosu

1969