chlorambucil has been researched along with Prolymphocytic Leukemia in 4 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Although hypercalcemia is more frequently found in T-cell leukaemia associated with human T lymphotropic lymphocyte type I, scattered reports indicate that patients with B-CLL can also be affected with this metabolic disturbance." | 2.39 | B-CLL in PLL transformation associated with hypercalcemia. ( De Oliveira, MS; Esteves, C; Lerner, D, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zver, S | 1 |
| Kokalj Vokac, N | 1 |
| Zagradisnik, B | 1 |
| Erjavec, A | 1 |
| Zagorac, A | 1 |
| Zupan, IP | 1 |
| Cernelc, P | 1 |
| Doorduijn, JK | 1 |
| Michiels, JJ | 1 |
| Lerner, D | 1 |
| Esteves, C | 1 |
| De Oliveira, MS | 1 |
| Islam, A | 1 |
| Majer, R | 1 |
| Cumber, P | 1 |
| Poynton, C | 1 |
1 review available for chlorambucil and Prolymphocytic Leukemia
| Article | Year |
|---|---|
B-CLL in PLL transformation associated with hypercalcemia.
Topics: Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Chlorambucil; Cyclophosph | 1994 |
3 other studies available for chlorambucil and Prolymphocytic Leukemia
| Article | Year |
|---|---|
T cell prolymphocytic leukemia with new chromosome rearrangements.
Topics: Aged; Chlorambucil; Chromobox Protein Homolog 5; Chromosome Aberrations; Female; Humans; Karyotyping | 2004 |
Effectiveness of fludarabine in end-stage prolymphocytic leukemia.
Topics: Aged; Anemia; Antigens, CD; Antineoplastic Agents; Blood Transfusion; Chlorambucil; Female; Humans; | 1994 |
Chlorambucil and prednisolone therapy in a patient with T-cell chronic lymphocytic leukaemia.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Female; Humans; Immunophenotypin | 1996 |