chlorambucil has been researched along with Pregnancy in 88 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
Excerpt | Relevance | Reference |
---|---|---|
"The widely accepted standard therapy for cutaneous sarcoidosis includes corticosteroids, antimalarials, and methotrexate." | 4.84 | Cutaneous sarcoidosis therapy updated. ( Badgwell, C; Rosen, T, 2007) |
" Methotrexate, azathioprine, mycophenolate mofetil, cyclosporin cyclophosphamide, chlorambucil, and other related drugs have potential benefits in the treatment of severe and/or recalcitrant rheumatic skin diseases." | 4.81 | Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders. ( Callen, JP, 2001) |
"This report describes a 53-year-old white woman with metastatic gestational trophoblastic neoplasia that recurred after evacuation of an accidental pregnancy and did not respond sufficiently to treatment with a combination of methotrexate, actinomycin D, and chlorambucil." | 3.67 | Chemotherapy-resistant gestational trophoblastic neoplasia treated successfully with cisplatin, etoposide, and bleomycin. ( Aalders, JG; Bouma, J; Sleijfer, DT; Willemse, PH, 1988) |
"The clinical features of patients with brain metastases are reviewed in detail." | 1.29 | Brain metastases of gestational trophoblastic tumor. ( Bakri, Y; Berkowitz, RS; Goldstein, DP; Jabbar, FA; Senoussi, M; Subhi, J; von Sinner, W, 1994) |
"Surgery combined with chemotherapy was applied in 34 out of 178 patients (19." | 1.29 | Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD). ( Kietlińska, Z; Sablińska, B; Zieliński, J, 1993) |
"Of 19 patients with gestational trophoblastic tumor and liver metastases, 6 received MAC chemotherapy, and 8 received PEA." | 1.29 | Liver metastases of gestational trophoblastic tumor. ( Amer, M; Bakri, YN; Ezzat, A; Jabbar, FA; Sinner, W; Subhi, J; Tweijry, A, 1993) |
"Chlorambucil (CHL) was administered ip on d 11 of gestation at doses of 0, 3, and 6 mg/kg; nitrofen (2,4-dichlorophenyl p-nitrophenyl ether) (NIT) was given po on d 8-16 of gestation at 0, 4." | 1.27 | Morphometric, biochemical, and physiological assessment of perinatally induced renal dysfunction. ( Gray, JA; Kavlock, RJ, 1983) |
"Chlorambucil was three times more potent than cyclophosphamide on an mg/kg basis." | 1.26 | Aspects of the teratology of cyclophosphamide (NSC-26271). ( Ashby, R; Davis, L; Dewhurst, BB; Espinal, R; Penn, RN; Upshall, DG, 1976) |
" They type and frequency of malformations differed according to the dosage and day of treatment." | 1.25 | Teratogenic effects of chlorambucil on in vivo and in vitro organogenesis in mice. ( Kochhar, DM; Salder, TW, 1975) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 74 (84.09) | 18.7374 |
1990's | 11 (12.50) | 18.2507 |
2000's | 3 (3.41) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ali, R | 1 |
Ozkalemkas, F | 1 |
Kimya, Y | 1 |
Koksal, N | 1 |
Ozkocaman, V | 1 |
Yorulmaz, H | 1 |
Eroglu, A | 1 |
Ozcelik, T | 1 |
Tunali, A | 1 |
SHOTTON, D | 1 |
MONIE, IW | 1 |
SULLI, G | 1 |
HRESCHCHYSHYN, MM | 1 |
BREWER, JI | 1 |
GERBIE, AB | 1 |
DOLKART, RE | 1 |
SKOM, JH | 1 |
NAGLE, RG | 1 |
TOROK, EE | 1 |
EDMONDS, LC | 1 |
CARRERA, GM | 1 |
RUGH, R | 2 |
SKAREDOFF, L | 1 |
Badgwell, C | 1 |
Rosen, T | 1 |
Soukup, S | 1 |
Takacs, E | 1 |
Warkany, J | 1 |
Giavini, E | 1 |
Bonanomi, L | 1 |
Ornaghi, F | 1 |
Harder, M | 1 |
Limacher, F | 1 |
Kavlock, RJ | 3 |
Gray, JA | 1 |
Lurain, JR | 1 |
Piver, MS | 1 |
Sablińska, B | 2 |
Cześnin, K | 1 |
Ploch, E | 1 |
Jones, WB | 2 |
Fujii, T | 1 |
Nakatsuka, T | 1 |
Mirkes, PE | 1 |
Greenaway, JC | 1 |
Steege, JF | 1 |
Caldwell, DS | 1 |
Bakri, Y | 1 |
Berkowitz, RS | 1 |
Goldstein, DP | 1 |
Subhi, J | 2 |
Senoussi, M | 1 |
von Sinner, W | 1 |
Jabbar, FA | 2 |
Hammond, CB | 4 |
Olt, GJ | 1 |
Kietlińska, Z | 1 |
Zieliński, J | 1 |
Bakri, YN | 1 |
Amer, M | 1 |
Ezzat, A | 1 |
Sinner, W | 1 |
Tweijry, A | 1 |
Powell, JL | 1 |
Johnson, NA | 1 |
Bailey, CL | 1 |
Otis, CN | 1 |
Generoso, WM | 1 |
Witt, KL | 1 |
Cain, KT | 1 |
Hughes, L | 1 |
Cacheiro, NL | 1 |
Lockhart, AM | 1 |
Shelby, MD | 1 |
Bermas, BL | 1 |
Hill, JA | 1 |
Ramsey-Goldman, R | 1 |
Schilling, E | 1 |
Callen, JP | 2 |
Lewis, JL | 1 |
Lehr, M | 1 |
Galbraith, RM | 1 |
Eddleston, AL | 1 |
Williams, R | 1 |
Zuckerman, AJ | 1 |
Ross, GT | 2 |
Becker, RL | 1 |
Avioli, LV | 1 |
Tscherne, G | 1 |
Einhorn, LH | 1 |
Hoffman, R | 1 |
Wasserman, LR | 1 |
Schaison, G | 1 |
Jacquillat, C | 1 |
Auclerc, G | 1 |
Weil, M | 1 |
Brummett, ES | 1 |
Johnson, EM | 1 |
Pratt, RA | 1 |
Di Chiro, G | 1 |
Weed, JC | 1 |
Schiffman, FJ | 1 |
Fisher, JM | 1 |
Rabinovitz, M | 1 |
O'Neill, E | 1 |
Pelegrina, I | 1 |
Vicens, R | 1 |
Almodóvar, AR | 1 |
Sadler, TW | 1 |
Kochhar, DM | 2 |
Baumgartner, G | 1 |
Stutzman, L | 2 |
Zipori, D | 1 |
Trainin, N | 1 |
Brandt, L | 1 |
Kónyves, I | 1 |
Móller, TR | 1 |
Salder, TW | 1 |
Ashby, R | 1 |
Davis, L | 1 |
Dewhurst, BB | 1 |
Espinal, R | 1 |
Penn, RN | 1 |
Upshall, DG | 1 |
Ba-Thike, K | 1 |
Oo, N | 1 |
Mortakis, AE | 1 |
Braga, CA | 1 |
Willemse, PH | 1 |
Aalders, JG | 1 |
Bouma, J | 1 |
Sleijfer, DT | 1 |
du Toit, JP | 1 |
Curry, SL | 1 |
Blessing, JA | 1 |
DiSaia, PJ | 1 |
Soper, JT | 1 |
Twiggs, LB | 1 |
Gerulath, AH | 1 |
Dembo, AJ | 1 |
Aitken, S | 1 |
Quirt, IC | 1 |
Osborne, R | 1 |
Blackstein, M | 1 |
Rider, WD | 1 |
Takamizawa, H | 1 |
Sekiya, S | 1 |
Kobayashi, O | 1 |
Matsui, H | 1 |
Tanaka, O | 1 |
Rehnberg, BF | 2 |
Rogers, EH | 2 |
Lajos, L | 1 |
Székely, J | 1 |
Major, A | 1 |
Balogh, S | 1 |
Bücs, G | 1 |
Semenovskiĭ, AV | 1 |
Bret, AJ | 1 |
Grépinet, J | 1 |
Woodruff, JD | 2 |
Protos, P | 1 |
Peterson, WF | 1 |
Clavert, A | 1 |
Gabriel-Robez, O | 1 |
Armstrong, JG | 1 |
Parker, RT | 2 |
Li, MC | 1 |
Bloomfield, RD | 1 |
Ober, WB | 1 |
Edgcomb, JH | 1 |
Price, EB | 1 |
Borchert, LG | 1 |
Tyrey, L | 1 |
Creasman, WT | 1 |
Klener, P | 1 |
Hervet, E | 1 |
Barrat, J | 1 |
Darbois, Y | 1 |
Faguer, C | 1 |
Shepard, TH | 1 |
Skinner, MD | 1 |
Schwartz, RS | 1 |
Forbes, IJ | 1 |
Zittoun, R | 1 |
Drox, JP | 1 |
de Carbonniére, C | 1 |
Bernadou, A | 1 |
Bilski-Pasquier, G | 1 |
Bousser, J | 1 |
Sandström, B | 1 |
Sokal, JE | 1 |
Baum, J | 1 |
Vaughan, J | 1 |
Julian, CG | 1 |
Mayr, E | 1 |
Jacobs, EM | 1 |
Johnson, FD | 1 |
Froud, PJ | 1 |
Henderson, AH | 1 |
Kernis, MM | 1 |
Marcus, SL | 1 |
Wider, JA | 1 |
Marshall, JR | 1 |
Bardin, CW | 1 |
Lipsett, MB | 1 |
19 reviews available for chlorambucil and Pregnancy
Article | Year |
---|---|
[MEDICAL THERAPY OF MALIGNANT NEOPLASMS].
Topics: Antimetabolites; Antineoplastic Agents; Antiviral Agents; Blood Transfusion; Busulfan; Chlorambucil; | 1964 |
Cutaneous sarcoidosis therapy updated.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Allopurinol; Animals; Anti-Inflammatory Agents | 2007 |
Management of advanced juvenile granulosa cell tumor of the ovary.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; | 1993 |
Effects of immunosuppressive drugs during pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Azathioprine; Chlorambucil; Cyclophos | 1995 |
Immunosuppressive drug use during pregnancy.
Topics: Adrenal Cortex Hormones; Animals; Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Female | 1997 |
Immunosuppressive and cytotoxic drugs in the treatment of rheumatic skin disorders.
Topics: Adult; Alkylating Agents; Antimetabolites; Azathioprine; Child; Chlorambucil; Cladribine; Cyclophosp | 2001 |
[New aspects of diagnosis, treatment and follow-up of trophoblastic tumours (author's transl)].
Topics: Adult; Aftercare; Brain Neoplasms; Chlorambucil; Chorionic Gonadotropin; Dactinomycin; Drug Therapy, | 1979 |
Natural history and management of polycythemia vera.
Topics: Acute Disease; Adult; Antineoplastic Agents; Bloodletting; Cell Transformation, Neoplastic; Chloramb | 1979 |
Chlorambucil.
Topics: Animals; Carcinogens; Chlorambucil; Drug Evaluation, Preclinical; Female; Fetus; Humans; Lethal Dose | 1975 |
Current status of treatment of lymphomas.
Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Therapy, Combin | 1975 |
Immunosuppressive and cytotoxic drugs: uses in the dermatologic patient.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Drug Interactions; Female; Humans; Immunosuppressive A | 1990 |
[Chemotherapy of trophoblastic disease].
Topics: Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Cyc | 1974 |
Trophoblastic disease: natural history, diagnosis, and treatment.
Topics: Alkylating Agents; Aminopterin; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; | 1971 |
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; | 1971 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
Use of anticancer drugs during pregnancy.
Topics: Alkylating Agents; Aminopterin; Animals; Antimetabolites; Antineoplastic Agents; Busulfan; Chlorambu | 1968 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Humans; Immunosuppressi | 1969 |
The role of chemotherapy in the treatment of primary ovarian malignancy.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl | 1969 |
[Antirheumatics. 40].
Topics: Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Chlorambucil; Female; Humans; Immunosu | 1969 |
3 trials available for chlorambucil and Pregnancy
Article | Year |
---|---|
A prospective randomized comparison of methotrexate, dactinomycin, and chlorambucil versus methotrexate, dactinomycin, cyclophosphamide, doxorubicin, melphalan, hydroxyurea, and vincristine in "poor prognosis" metastatic gestational trophoblastic disease:
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin; | 1989 |
Vinca alkaloids. Experimental and clinical trials.
Topics: Animals; Cell Movement; Chlorambucil; Choriocarcinoma; Female; Hematopoiesis; Hematopoietic Stem Cel | 1974 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
67 other studies available for chlorambucil and Pregnancy
Article | Year |
---|---|
Pregnancy in chronic lymphocytic leukemia: experience with fetal exposure to chlorambucil.
Topics: Adult; Allopurinol; Antimetabolites; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Fetus; | 2009 |
POSSIBLE TERATOGENIC EFFECT OF CHLORAMBUCIL ON A HUMAN FETUS.
Topics: Chlorambucil; Congenital Abnormalities; Female; Fetus; Hodgkin Disease; Humans; Pregnancy; Pregnancy | 1963 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
CHEMOTHERAPY IN TROPHOBLASTIC DISEASES.
Topics: Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Drug Therapy; Female; Gestation | 1964 |
EXTRAGENITAL CHORIOCARCINOMA.
Topics: Autopsy; Brain Neoplasms; Child; Chlorambucil; Choriocarcinoma; Dactinomycin; Drug Therapy; Epistaxi | 1965 |
RADIATION AND RADIOMIMETRIC CHLORAMBUCIL AND THE FETAL RETINA.
Topics: Abnormalities, Drug-Induced; Animals; Biomedical Research; Chlorambucil; Congenital Abnormalities; E | 1965 |
Chromosome changes in embryos treated with various teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Chlorambucil; Chromosome Aberrations; Diet; Female; Hydroxyure | 1967 |
Developmental toxicity during the preimplantation period: embryotoxicity and clastogenic effects of chlorambucil in the rat.
Topics: Animals; Blastocyst; Bone Marrow; Cell Nucleus; Chlorambucil; Embryo Implantation; Embryonic Develop | 1984 |
[Generalized metastasizing chorion carcinoma with complete remission after cytostatic therapy].
Topics: Adult; Breast Neoplasms; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Cyclophosphamide; Da | 1983 |
Morphometric, biochemical, and physiological assessment of perinatally induced renal dysfunction.
Topics: Age Factors; Animals; Animals, Newborn; Chlorambucil; Deamino Arginine Vasopressin; Diuresis; Dogs; | 1983 |
Metastatic gestational trophoblastic disease: secondary chemotherapy.
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Humans; Methot | 1980 |
[Management of trophoblastic disease].
Topics: Adolescent; Adult; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; Follow-Up | 1980 |
Management of low-risk metastatic gestational trophoblastic disease.
Topics: Antineoplastic Agents; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Humans; Hyster | 1981 |
Potentiating effects of caffeine on teratogenicity of alkylating agents in mice.
Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Alkylating Agents; Animals; Antibioti | 1983 |
Chlorambucil.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Chlorambucil; Drug Interactions; Female; Fetal | 1981 |
Teratogenicity of chlorambucil in rat embryos in vitro.
Topics: Abnormalities, Drug-Induced; Animals; Biotransformation; Chlorambucil; Cyclophosphamide; Dose-Respon | 1982 |
Renal agenesis after first trimester exposure to chlorambucil.
Topics: Abnormalities, Drug-Induced; Abortion, Therapeutic; Adult; Chlorambucil; Female; Humans; Kidney; Mal | 1980 |
Brain metastases of gestational trophoblastic tumor.
Topics: Adult; Antineoplastic Agents; Biomarkers, Tumor; Brain Neoplasms; Chlorambucil; Chorionic Gonadotrop | 1994 |
Gestational trophoblastic disease.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug A | 1994 |
Chemotherapy combined with surgery in the treatment of gestational trophoblastic disease (GTD).
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Chorioca | 1993 |
Liver metastases of gestational trophoblastic tumor.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Dactinomycin; Etopos | 1993 |
Dominant lethal and heritable translocation tests with chlorambucil and melphalan in male mice.
Topics: Animals; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Genes, Dominant; Genes, Lethal; Ge | 1995 |
Monitor of chemotherapy in gestational trophoblastic neoplasm by radioimmunoassay of the beta-subunit of human chorionic gonadotropin.
Topics: Adult; Antineoplastic Agents; Biological Assay; Bleomycin; Chlorambucil; Choriocarcinoma; Chorionic | 1975 |
Fulminant hepatic failure in leukaemia and choriocarcinoma related to withdrawal of cytotoxic drug therapy.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; | 1975 |
Congenital anomalies among children born of mothers receiving chemotherapy for gestational trophoblastic neoplasms.
Topics: Abnormalities, Drug-Induced; Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; | 1976 |
Gestational trophoblastic disease.
Topics: Adult; Brain Neoplasms; Cerebral Hemorrhage; Chlorambucil; Choriocarcinoma; Dactinomycin; Female; He | 1977 |
Cancer chemotherapy.
Topics: Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Female; Hodgkin Disease; Humans; Leuk | 1977 |
[Fetal risk of cancer chemotherapy (author's transl)].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Adult; Alkaloids; Animals; Antibiotics, Antineop | 1979 |
Morphological alterations in the developing fetal rat limb due to maternal injection of chlorambucil.
Topics: Animals; Bone and Bones; Bone Development; Chlorambucil; Extremities; Female; Gestational Age; Mater | 1979 |
Cerebral necrosis following irradiation and chemotherapy for metastatic choriocarcinoma.
Topics: Adult; Antineoplastic Agents; Brain; Brain Diseases; Brain Neoplasms; Chlorambucil; Choriocarcinoma; | 1977 |
Serum displacing agents in cancer chemotherapy.
Topics: Animals; Cattle; Cells, Cultured; Chemical Phenomena; Chemistry; Chlorambucil; Clofibrate; Culture M | 1977 |
Normal pregnancy and delivery after cerebral metastases of choriocarcinoma: Case report.
Topics: Adolescent; Brain Neoplasms; Chlorambucil; Choriocarcinoma; Dactinomycin; Drug Therapy, Combination; | 1976 |
Chlorambucil-induced cell death in embryonic mouse limb buds.
Topics: Acid Phosphatase; Animals; Cells, Cultured; Chlorambucil; Cytoplasm; Embryo, Mammalian; Extremities; | 1976 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
The role of a thymus humoral factor in the proliferation of bone marrow CFU-S from thymectomized mice.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cell Division; Chlorambucil; C | 1975 |
Therapeutic effect of Leo 1031, an alkylating corticosteroid ester, in lymphoproliferative disorders. I. chronic lymphocytic leukaemia.
Topics: Adult; Aged; Chlorambucil; Drug Evaluation; Esters; Female; Humans; Leukemia, Lymphoid; Male; Middle | 1975 |
Teratogenic effects of chlorambucil on in vivo and in vitro organogenesis in mice.
Topics: Abnormalities, Drug-Induced; Animals; Cells, Cultured; Chlorambucil; Female; Fetus; Gestational Age; | 1975 |
Aspects of the teratology of cyclophosphamide (NSC-26271).
Topics: Abnormalities, Drug-Induced; Alkylation; Animals; Chemical Phenomena; Chemistry; Chlorambucil; Cyclo | 1976 |
Non-Hodgkin's lymphoma in pregnancy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophosphamide; Female; Fetus | 1990 |
"Poor prognosis" metastatic gestational trophoblastic disease: the prognostic significance of the scoring system in predicting chemotherapy failures.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chlorambucil; Choriocarcinom | 1990 |
Chemotherapy-resistant gestational trophoblastic neoplasia treated successfully with cisplatin, etoposide, and bleomycin.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Dactinomycin; Et | 1988 |
High risk malignant gestational trophoblastic disease: experience with triple chemotherapy (MAC) in Third World circumstances.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dactinomycin; Female; Humans; L | 1989 |
Poor prognosis metastatic gestational trophoblastic disease: experience with moderate dose methotrexate plus folinic acid rescue as initial therapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chlorambucil; Chorionic Gonadotropi | 1986 |
Chemotherapy for gestational trophoblastic tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropi | 1987 |
[Abnormalities of brain differentiation induced by chemical agents].
Topics: Abnormalities, Drug-Induced; Animals; Brain; Chlorambucil; Female; Mice; Neural Tube Defects; Oncoge | 1988 |
Chlorambucil induced congenital renal hypoplasia: effects on basal renal function in the developing rat.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Chlorambucil; Dose-Response Relationship, Drug; Female; K | 1986 |
Critical prenatal periods for chlorambucil-induced functional alterations of the rat kidney.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Chlorambucil; Female; Gestational Age; Kidney; Li | 1987 |
[Importance of chemotherapeutic agents in the treatment of malignant trophoblast tumors].
Topics: Adnexa Uteri; Adult; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Hu | 1969 |
[Uterine chorioepithelioma].
Topics: Abortion, Spontaneous; Adult; Antineoplastic Agents; Chlorambucil; Chloramines; Choriocarcinoma; Dac | 1966 |
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin | 1968 |
[Ocular abnormalities induced by chloraminophene in the mouse].
Topics: Animals; Atrophy; Chlorambucil; Eye; Female; Lens, Crystalline; Mice; Morphogenesis; Optic Nerve; Pr | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
Diagnosis and treatment of trophoblastic disease. A report from the Southeastern Regional Center.
Topics: Adult; Antineoplastic Agents; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; D | 1970 |
The pathology of choriocarcinoma.
Topics: Adolescent; Adult; Age Factors; Animals; Autopsy; Child; Chlorambucil; Choriocarcinoma; Chorionic Go | 1971 |
Treatment of metastatic trophoblastic disease: good and poor prognosis.
Topics: Brain Neoplasms; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Follow | 1973 |
[Letter: Teratogenic effects of medications].
Topics: Abnormalities, Drug-Induced; Adult; Chlorambucil; Female; Humans; Hydroxyurea; Leukemia, Lymphoid; M | 1974 |
Teratogenicity from drugs--an increasing problem.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Aminopterin; Amniocentesis; Animals; Anti-Bact | 1974 |
The clinical use of immunosuppressive drugs.
Topics: Adrenal Cortex Hormones; Aged; Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; | 1973 |
[The evolution of idiopathic autoimmune hemolytic anemia].
Topics: Age Factors; Anemia, Hemolytic, Autoimmune; Antibodies; Chlorambucil; Cyclophosphamide; Female; Huma | 1973 |
[Malignant mole and choriocarcinoma].
Topics: Chlorambucil; Choriocarcinoma; Female; Humans; Hydatidiform Mole; Methotrexate; Pregnancy; Prognosis | 1973 |
Radiobiology. NYO-2740-4.
Topics: Animals; Animals, Newborn; Cataract; Chlorambucil; Embryo, Mammalian; Female; Fetus; Haplorhini; Hum | 1967 |
Cytotoxic agents in the treatment of malignant disease.
Topics: Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Chlorambucil; Choriocarcinoma; | 1968 |
Gestational choriocarcinoma.
Topics: Adult; California; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Female; Huma | 1972 |
The treatment of Wegener's granulomatosis with immunosuppressive-cytotoxic drugs.
Topics: Adult; Azathioprine; Chlorambucil; Female; Granulomatosis with Polyangiitis; Humans; Male; Methylpre | 1971 |
Abnormal yolk sac function induced by chlorambucil.
Topics: Abnormalities, Drug-Induced; Animals; Carbon Isotopes; Chlorambucil; Embryo, Mammalian; Extraembryon | 1971 |
Effect of induced leukopenia on the contraceptive action of an intrauterine device in the rat.
Topics: Animals; Chlorambucil; Contraception; Embryo Implantation; Endometrium; Exudates and Transudates; Fe | 1971 |
Sustained remissions after chemotherapy for primary ovarian cancers containing choriocarcinoma.
Topics: Adolescent; Adult; Child; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Dysge | 1969 |