chlorambucil has been researched along with Peripheral Nervous System Diseases in 9 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Peripheral Nervous System Diseases: Diseases of the peripheral nerves external to the brain and spinal cord, which includes diseases of the nerve roots, ganglia, plexi, autonomic nerves, sensory nerves, and motor nerves.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Waldenström's macroglobulinemia is a rare malignant disorder of B lymphocytes." | 2.70 | IFN-alpha as induction and maintenance treatment of patients newly diagnosed with Waldenström's macroglobulinemia. ( Abraham-Majluf, S; Arenas-Osuna, J; Aviña-Zubieta, JA; García-Chávez, J; García-Ruiz Esparza, MA; Padilla-González, Y; Rosas-Cabral, A; Salazar-Exaire, D; Vadillo-Buenfil, M; Vela-Ojeda, J; Xolotl-Castillo, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (55.56) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vela-Ojeda, J | 1 |
| García-Ruiz Esparza, MA | 1 |
| Padilla-González, Y | 1 |
| Rosas-Cabral, A | 1 |
| García-Chávez, J | 1 |
| Xolotl-Castillo, M | 1 |
| Salazar-Exaire, D | 1 |
| Arenas-Osuna, J | 1 |
| Aviña-Zubieta, JA | 1 |
| Vadillo-Buenfil, M | 1 |
| Abraham-Majluf, S | 1 |
| Meier, C | 1 |
| Roberts, K | 1 |
| Steck, A | 1 |
| Hess, C | 1 |
| Miloni, E | 1 |
| Tschopp, L | 1 |
| Geltner, D | 1 |
| Kohn, RW | 1 |
| Gorevic, P | 1 |
| Franklin, EC | 1 |
| Dalakas, MC | 1 |
| Flaum, MA | 1 |
| Rick, M | 1 |
| Engel, WK | 1 |
| Gralnick, HR | 1 |
| Oksenhendler, E | 1 |
| Chevret, S | 1 |
| Léger, JM | 1 |
| Louboutin, JP | 1 |
| Bussel, A | 1 |
| Brouet, JC | 1 |
| Vigushin, DM | 1 |
| Hawkins, PN | 1 |
| Hsuan, JJ | 1 |
| Totty, NF | 1 |
| Pepys, MB | 1 |
| Mateos-Colino, A | 1 |
| Gonzalez-Gay, MA | 1 |
| Cereijo, MJ | 1 |
| Santiago, J | 1 |
| Rabuñal, R | 1 |
| Brañas, F | 1 |
| Sandler, RM | 1 |
| Gonsalkorale, M | 1 |
| Nobile-Orazio, E | 1 |
| Baldini, L | 1 |
| Barbieri, S | 1 |
| Marmiroli, P | 1 |
| Spagnol, G | 1 |
| Francomano, E | 1 |
| Scarlato, G | 1 |
2 trials available for chlorambucil and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
IFN-alpha as induction and maintenance treatment of patients newly diagnosed with Waldenström's macroglobulinemia.
Topics: Aged; Chlorambucil; Disease-Free Survival; Drug Administration Schedule; Drug Therapy, Combination; | 2002 |
Plasma exchange and chlorambucil in polyneuropathy associated with monoclonal IgM gammopathy. IgM-associated Polyneuropathy Study Group.
Topics: Aged; Chlorambucil; Female; Humans; Immunoglobulin M; Male; Middle Aged; Neural Conduction; Paraprot | 1995 |
7 other studies available for chlorambucil and Peripheral Nervous System Diseases
| Article | Year |
|---|---|
Polyneuropathy in Waldenström's macroglobulinaemia: reduction of endoneurial IgM-deposits after treatment with chlorambucil and plasmapheresis.
Topics: Chlorambucil; Humans; Immunoglobulin M; Male; Middle Aged; Peripheral Nerves; Peripheral Nervous Sys | 1984 |
The effect of combination therapy (steroids, immunosuppressives, and plasmapheresis) on 5 mixed cryoglobulinemia patients with renal, neurologic, and vascular involvement.
Topics: Aged; Chlorambucil; Cryoglobulinemia; Female; Humans; Kidney Diseases; Male; Middle Aged; Paraprotei | 1981 |
Treatment of polyneuropathy in Waldenström's macroglobulinemia: role of paraproteinemia and immunologic studies.
Topics: B-Lymphocytes; Chlorambucil; Female; Humans; Immunoglobulin M; Middle Aged; Neurons; Peripheral Nerv | 1983 |
AL kappa amyloid in a solitary extradural lymphoma.
Topics: Aged; Amino Acid Sequence; Amyloid; Chlorambucil; Combined Modality Therapy; Craniotomy; Dysarthria; | 1994 |
[Neuro-Behçet: a follow-up of 4 cases treated with chlorambucil].
Topics: Adult; Antineoplastic Agents, Alkylating; Behcet Syndrome; Brain Diseases; Chlorambucil; Drug Therap | 1995 |
Chronic lymphatic leukaemia, chlorambucil, and sensorimotor peripheral neuropathy.
Topics: Chlorambucil; Humans; Leukemia, Lymphoid; Male; Middle Aged; Peripheral Nervous System Diseases; Pre | 1977 |
Treatment of patients with neuropathy and anti-MAG IgM M-proteins.
Topics: Aged; Antineoplastic Agents; Autoantibodies; Blood Proteins; Chlorambucil; Cyclophosphamide; Humans; | 1988 |