chlorambucil has been researched along with Pemphigus in 8 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Pemphigus: Group of chronic blistering diseases characterized histologically by ACANTHOLYSIS and blister formation within the EPIDERMIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We retrospectively reviewed the medical records of 9 patients with pemphigus (7 with pemphigus vulgaris and 2 with pemphigus foliaceus) in whom therapy with other immunosuppressive regimens failed and who were subsequently treated with chlorambucil and prednisone." | 7.70 | The use of chlorambucil with prednisone in the treatment of pemphigus. ( Elgart, GW; Green, AR; Kerdel, F; Shah, N, 2000) |
| "We retrospectively reviewed the medical records of 9 patients with pemphigus (7 with pemphigus vulgaris and 2 with pemphigus foliaceus) in whom therapy with other immunosuppressive regimens failed and who were subsequently treated with chlorambucil and prednisone." | 3.70 | The use of chlorambucil with prednisone in the treatment of pemphigus. ( Elgart, GW; Green, AR; Kerdel, F; Shah, N, 2000) |
| "Pemphigus is an autoimmune skin disease that can present in a variety of forms and can be a challenging disease to manage and treat." | 2.42 | Pemphigus: current therapy. ( Rosenkrantz, WS, 2004) |
| "Paraneoplastic pemphigus is an autoimmune disease of the skin and mucosa described in 1990." | 1.31 | [Paraneoplastic pemphigus: a pustular form during chronic lymphoid leukemia]. ( Huttenberger, B; Jan, V; Joly, P; Lorette, G; Machet, MC; Martin, L; Rivollier, C; Vaillant, L, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peterson, A | 1 |
| McKay, L | 1 |
| Irwin, KE | 1 |
| Beale, KM | 1 |
| Fadok, VA | 1 |
| Gergely, L | 1 |
| Váróczy, L | 1 |
| Vadász, G | 1 |
| Remenyik, E | 1 |
| Illés, A | 1 |
| Rosenkrantz, WS | 1 |
| Cowley, NC | 1 |
| Neill, SM | 1 |
| Staughton, RC | 1 |
| Shah, N | 1 |
| Green, AR | 1 |
| Elgart, GW | 1 |
| Kerdel, F | 1 |
| Rivollier, C | 1 |
| Vaillant, L | 1 |
| Machet, MC | 1 |
| Martin, L | 1 |
| Jan, V | 1 |
| Huttenberger, B | 1 |
| Joly, P | 1 |
| Lorette, G | 1 |
| Degos, R | 1 |
| Civatte, J | 1 |
| Larrègue, M | 1 |
2 reviews available for chlorambucil and Pemphigus
| Article | Year |
|---|---|
Crusty cats: feline pemphigus foliaceus.
Topics: Animals; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Immunosuppressive Agents; Pemphigus | 2010 |
Pemphigus: current therapy.
Topics: Animals; Antirheumatic Agents; Azathioprine; Chlorambucil; Cyclophosphamide; Cyclosporine; Dapsone; | 2004 |
6 other studies available for chlorambucil and Pemphigus
| Article | Year |
|---|---|
Use of modified ciclosporin in the management of feline pemphigus foliaceus: a retrospective analysis.
Topics: Animals; Cat Diseases; Cats; Chlorambucil; Cyclosporine; Dose-Response Relationship, Drug; Female; G | 2012 |
Successful treatment of B cell chronic lymphocytic leukemia-associated severe paraneoplastic pemphigus with cyclosporin A.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; Cyclophosph | 2003 |
Pemphigus foliaceus and non-Hodgkin's lymphoma.
Topics: Allopurinol; Chlorambucil; Drug Therapy, Combination; Female; Fluorescent Antibody Technique; Humans | 1994 |
The use of chlorambucil with prednisone in the treatment of pemphigus.
Topics: Adult; Aged; Alkylating Agents; Chlorambucil; Drug Therapy, Combination; Female; Glucocorticoids; Hu | 2000 |
[Paraneoplastic pemphigus: a pustular form during chronic lymphoid leukemia].
Topics: Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Biopsy; Chlorambucil; Drug Therapy, Com | 2001 |
[Treatment of Duhring-Brocq disease with chloraminophene].
Topics: Adult; Aged; Autoantibodies; Basement Membrane; Chlorambucil; Complement Fixation Tests; Dermatitis | 1971 |