chlorambucil has been researched along with Pain in 6 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With long-term administration (the longest term, 20 weeks, 36 patients), the dose-limiting factor was concluded to be a decrease in the peripheral leukocyte count when the total amount administered reached about 10 g." | 1.27 | [Phase I study of bestrabucil (KM 2210)]. ( Agatsuma, T; Fugiwara, A; Fujita, K; Goto, T; Isurugi, K; Kamei, H; Kubota, T; Nakao, I; Suga, S; Takenaka, K, 1986) |
| "Estramustine has been shown previously to be an effective drug in the treatment of metastatic prostatic cancer, demonstrating significant objective and subjective responses in long-term non-randomized trials and in other randomized trials." | 1.26 | The use of estramustine and prednimustine versus prednimustine alone in advanced metastatic prostatic cancer patients who have received prior irradiation. ( Chu, TM; Gaeta, JF; Gibbons, RP; Johnson, DE; Loening, SA; Murphy, GP; Prout, GR; Saroff, J; Schmidt, JD; Scott, WW; Slack, N; Soloway, MS; Wajsman, Z, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HARMAN, JB | 1 |
| Beaver, WT | 1 |
| Trump, DL | 1 |
| Anderson, SA | 1 |
| Distelrath, K | 1 |
| Neuber, K | 1 |
| Blödorn-Schlicht, N | 1 |
| Altenhoff, J | 1 |
| Dührsen, U | 1 |
| Düring, J | 1 |
| Steinkraus, V | 1 |
| Murphy, GP | 1 |
| Gibbons, RP | 1 |
| Johnson, DE | 1 |
| Prout, GR | 1 |
| Schmidt, JD | 1 |
| Soloway, MS | 1 |
| Loening, SA | 1 |
| Chu, TM | 1 |
| Gaeta, JF | 1 |
| Saroff, J | 1 |
| Wajsman, Z | 1 |
| Slack, N | 1 |
| Scott, WW | 1 |
| Kamei, H | 1 |
| Takenaka, K | 1 |
| Goto, T | 1 |
| Suga, S | 1 |
| Fugiwara, A | 1 |
| Nakao, I | 1 |
| Agatsuma, T | 1 |
| Fujita, K | 1 |
| Isurugi, K | 1 |
| Kubota, T | 1 |
1 review available for chlorambucil and Pain
| Article | Year |
|---|---|
Analgesic efficacy of dextropropoxyphene and dextropropoxyphene-containing combinations: a review.
Topics: Acetaminophen; Aminoacridines; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Chlorambucil | 1984 |
1 trial available for chlorambucil and Pain
| Article | Year |
|---|---|
Analgesic efficacy of dextropropoxyphene and dextropropoxyphene-containing combinations: a review.
Topics: Acetaminophen; Aminoacridines; Antineoplastic Combined Chemotherapy Protocols; Aspirin; Chlorambucil | 1984 |
5 other studies available for chlorambucil and Pain
| Article | Year |
|---|---|
THE TREATMENT OF INCURABLE MALIGNANT DISEASE.
Topics: Adrenalectomy; Androgens; Breast Neoplasms; Busulfan; Chlorambucil; Estrogens; Heroin; Hormones; Hum | 1964 |
Painful gynecomastia following cytotoxic therapy for testis cancer: a potentially favorable prognostic sign?
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1983 |
[Painful ischemia of the extremities with T-cell lymphoma].
Topics: Chlorambucil; Female; Foot; Hand; Humans; Ischemia; Lymphoma, T-Cell; Male; Middle Aged; Pain; Predn | 1999 |
The use of estramustine and prednimustine versus prednimustine alone in advanced metastatic prostatic cancer patients who have received prior irradiation.
Topics: Chlorambucil; Drug Therapy, Combination; Estramustine; Humans; Male; Nausea; Neoplasm Metastasis; Ni | 1979 |
[Phase I study of bestrabucil (KM 2210)].
Topics: Adult; Aged; Animals; Anorexia; Chlorambucil; Dose-Response Relationship, Drug; Drug Administration | 1986 |