chlorambucil has been researched along with Ovarian Neoplasms in 135 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Three hundred and sixty-nine patients with advanced ovarian adenocarcinoma were treated in a prospective randomized trial comparing combination versus sequential therapy with chlorambucil and cisplatin." | 9.06 | Chemotherapy of advanced ovarian adenocarcinoma: a randomized comparison of combination versus sequential therapy using chlorambucil and cisplatin. ( , 1986) |
| "Fifty-six tumor specimens from patients with ovarian adenocarcinoma were tested for sensitivity to single and combination drug regimens in a short-term antimetabolic assay measuring inhibition of thymidine incorporation." | 7.68 | Combination chemotherapy tested in a short-term thymidine incorporation assay in primary cultures of ovarian adenocarcinomas. ( Hayward, IP; Hurst, T; Khoo, SK; Parsons, PG, 1992) |
| "It was discovered that for breast cancer cells, the new compounds were up to 4." | 5.38 | Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines. ( Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Leblanc, V; Parent, S, 2012) |
| "Three hundred and sixty-nine patients with advanced ovarian adenocarcinoma were treated in a prospective randomized trial comparing combination versus sequential therapy with chlorambucil and cisplatin." | 5.06 | Chemotherapy of advanced ovarian adenocarcinoma: a randomized comparison of combination versus sequential therapy using chlorambucil and cisplatin. ( , 1986) |
| "Seventeen patients with advanced ovarian adenocarcinoma recurring or progressing after prior treatment with chlorambucil and cis-platinum were treated with cyclophosphamide, adriamycin, and cis-platinum (CAP) every 3 weeks." | 5.05 | Combined cyclophosphamide, adriamycin and cis-platinum in advanced ovarian cancer resistant to chlorambucil and cis-platinum. ( Malden, LT; Mann, GJ; Solomon, HJ; Tattersall, MH, 1985) |
| "Drug resistance in cancer cells involves complex molecular mechanisms and ovarian carcinoma cells become resistant to chlorambucil (Cbl) after continuous treatment." | 3.76 | Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells. ( Maiti, AK, 2010) |
| "Fifty-six tumor specimens from patients with ovarian adenocarcinoma were tested for sensitivity to single and combination drug regimens in a short-term antimetabolic assay measuring inhibition of thymidine incorporation." | 3.68 | Combination chemotherapy tested in a short-term thymidine incorporation assay in primary cultures of ovarian adenocarcinomas. ( Hayward, IP; Hurst, T; Khoo, SK; Parsons, PG, 1992) |
| "Two cases of advanced ovarian carcinoma treated with chlorambucil and terminating in acute leukemia are presented and the literature reviewed." | 3.65 | Acute leukemia in advanced ovarian carcinoma after treatment with alkylating agents. ( Jafari, K; Lash, AF; Sotrel, G; Stepto, RC, 1976) |
| "Of 369 patients with apparent advanced ovarian cancer entered on a randomized trial between September 1979 and June 1983, 56 survived more than 5 years." | 2.67 | Long-term survival with advanced ovarian cancer: an analysis of 5-year survivors in the Australian trial comparing combination versus sequential chlorambucil and cisplatin therapy. ( Solomon, HJ; Swanson, CE; Tattersall, MH, 1992) |
| "Chlorambucil and melphalan were the most leukemogenic drugs, followed by thiotepa; cyclophosphamide and treosulfan were the weakest leukemogens, and the effect per gram was substantially lower at high doses than at lower doses." | 2.67 | Leukemia following chemotherapy for ovarian cancer. ( Bell, J; Clarke, EA; Day, NE; Høst, H; Kaldor, JM; Karjalainen, S; Mehnert, W; Pedersen, D; Pettersson, F; Prior, P, 1990) |
| "Prednimustine can produce durable responses in advanced ovarian cancer using a schedule that results in negligible toxicity." | 2.66 | Randomised trial comparing prednimustine with combination chemotherapy in advanced ovarian carcinoma. ( Cornbleet, MA; Fletcher, S; Kerr, GR; Leonard, RC; Livingstone, JR; Smart, GE; Smyth, JF; Webb, JN, 1989) |
| "Ninety-eight patients with advanced ovarian cancer took part in a prospective, randomised trial comparing low-dose cisplatin and chlorambucil with low-dose cisplatin, chlorambucil, and doxorubicin." | 2.65 | Randomised trial comparing low-dose cisplatin and chlorambucil with low-dose cisplatin, chlorambucil, and doxorubicin in advanced ovarian carcinoma. ( Barker, GH; Wiltshaw, E, 1981) |
| "We evaluated the occurrence of acute nonlymphocytic leukemia (ANL) among 1399 women with ovarian cancer who were treated in five randomized clinical trials." | 2.65 | Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials. ( Blessing, JA; Boice, JD; Dembo, AJ; Greene, MH; Greer, BE, 1982) |
| "Thirty-seven patients with advanced ovarian cancer were treated in a prospective, randomised trial comparing chlorambucil with a combination of cyclophosphamide and cis-diamminedichloroplatinum (cis DDP)." | 2.65 | Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum. ( Bell, DR; Fox, RM; Levi, JA; Tattersall, MH; Woods, RL, 1982) |
| "PDL1-expressing mouse and human ovarian cancer lines and mouse melanoma were more sensitive to chlorambucil-mediated proliferation inhibition in vitro versus corresponding genetically PDL1-depleted lines." | 1.91 | Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects. ( Bai, H; Conejo-Garcia, JR; Curiel, T; Deng, Y; Garcia, M; Gupta, HB; Kancharla, A; Kari, SJ; Kornepati, AVR; Liao, YJ; Murray, CJ; Ontiveros, C; Padron, AS; Reyes, RM, 2023) |
| "It was discovered that for breast cancer cells, the new compounds were up to 4." | 1.38 | Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines. ( Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Leblanc, V; Parent, S, 2012) |
| "The histologic diagnoses were six immature teratomas, five endodermal sinus tumors, four mixed germ cell tumors, and one nongestational choriocarcinoma." | 1.27 | Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary. ( Cain, JM; Hakes, TB; Lewis, JL; Pierce, VK; Pippitt, CH, 1988) |
| "In melphalan-treated patients where LCLs were established serially, the melphalan Do increased after further melphalan treatment in vivo and decreased when no further treatment was given." | 1.27 | Melphalan-resistant lymphoblastoid cell lines established from patients with ovarian cancer treated with cross-linking agents. ( Daunter, B; Khoo, SK; Maynard, K; Musk, P; Parsons, PG, 1985) |
| "Dysgerminomas are highly sensitive not only to irradiation but also to chemotherapy." | 1.27 | [Chemotherapy of dysgerminoma]. ( Brökelmann, J; Hartlapp, JH, 1987) |
| "Of 602 patients treated for non-Hodgkin's lymphomas, 9 developed overt acute nonlymphocytic leukemia or preleukemia with refractory cytopenia and cytogenetic abnormalities of the bone marrow." | 1.27 | Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents. ( Ersbøll, J; Keiding, N; Larsen, MS; Larsen, SO; Nissen, NI; Pedersen-Bjergaard, J; Philip, P; Schultz, H; Sørensen, HM, 1985) |
| " Treatment dosage on a few occasions was decreased and increased again, due to drops in hemoglobin level and white blood cell and platelet counts." | 1.26 | Long-term survival in a case of stage IV carcinoma of the ovary treated with a single chemotherapeutic agent. ( Akbiyik, N; Alexander, L; Solisio, E, 1979) |
| "Thirteen cases of acute nonlymphocytic leukemia occurred among 5455 patients, as compared to 0." | 1.26 | Acute leukemia after alkylating-agent therapy of ovarian cancer. ( Fraumeni, JF; Hoover, R; Reimer, RR; Young, RC, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 112 (82.96) | 18.7374 |
| 1990's | 12 (8.89) | 18.2507 |
| 2000's | 4 (2.96) | 29.6817 |
| 2010's | 4 (2.96) | 24.3611 |
| 2020's | 3 (2.22) | 2.80 |
| Authors | Studies |
|---|---|
| Aputen, AD | 1 |
| Elias, MG | 1 |
| Gilbert, J | 1 |
| Sakoff, JA | 1 |
| Gordon, CP | 1 |
| Scott, KF | 1 |
| Aldrich-Wright, JR | 1 |
| Bai, H | 1 |
| Padron, AS | 1 |
| Deng, Y | 1 |
| Liao, YJ | 1 |
| Murray, CJ | 1 |
| Ontiveros, C | 1 |
| Kari, SJ | 1 |
| Kancharla, A | 1 |
| Kornepati, AVR | 1 |
| Garcia, M | 1 |
| Reyes, RM | 1 |
| Gupta, HB | 1 |
| Conejo-Garcia, JR | 1 |
| Curiel, T | 1 |
| Huang, P | 1 |
| Wang, G | 1 |
| Wang, Z | 1 |
| Zhang, C | 1 |
| Wang, F | 1 |
| Cui, X | 1 |
| Guo, S | 1 |
| Huang, W | 1 |
| Zhang, R | 1 |
| Yan, D | 1 |
| Jean, SR | 1 |
| Pereira, MP | 1 |
| Kelley, SO | 1 |
| Maiti, AK | 1 |
| Clavel, CM | 1 |
| Zava, O | 1 |
| Schmitt, F | 1 |
| Kenzaoui, BH | 1 |
| Nazarov, AA | 1 |
| Juillerat-Jeanneret, L | 1 |
| Dyson, PJ | 1 |
| Descôteaux, C | 1 |
| Brasseur, K | 1 |
| Leblanc, V | 1 |
| Parent, S | 1 |
| Asselin, E | 1 |
| Bérubé, G | 1 |
| WILLIAMS, HM | 1 |
| GENTIL, F | 1 |
| MOORE, JG | 1 |
| VANCAMPENHOUT, JL | 1 |
| BRANDKAMP, WW | 1 |
| LOPESCARDOZO, E | 1 |
| PAPAVASILIOU, C | 1 |
| KOSTOUROS, D | 1 |
| ZELENIK, JS | 1 |
| HALPERN, AJ | 1 |
| WILLIAMS, DW | 1 |
| MIALE, A | 1 |
| KESLER, K | 1 |
| HRESCHCHYSHYN, MM | 1 |
| LEBHERZ, TB | 2 |
| HUSTON, JW | 1 |
| AUSTIN, JA | 1 |
| BOYCE, CR | 1 |
| PARKER, RT | 1 |
| WILTSHAW, E | 5 |
| MASTERSON, JG | 1 |
| CALAME, RJ | 1 |
| NELSON, J | 1 |
| MILLER, SP | 2 |
| BRENNER, SM | 1 |
| Boldogh, I | 3 |
| Roy, G | 3 |
| Lee, MS | 1 |
| Bacsi, A | 1 |
| Hazra, TK | 1 |
| Bhakat, KK | 1 |
| Das, GC | 1 |
| Mitra, S | 3 |
| Barker, GH | 1 |
| Grundsell, H | 2 |
| Johnsson, JE | 2 |
| Tropé, C | 2 |
| Szepesi, T | 2 |
| Kärcher, KH | 1 |
| Seitz, W | 1 |
| Kogelnik, HD | 1 |
| Reinartz, G | 1 |
| Janisch, H | 2 |
| Szalay, S | 3 |
| Breitenecker, G | 1 |
| Schratter-Sehn, A | 1 |
| Rogan, AM | 1 |
| Riss, T | 1 |
| Wittich, G | 1 |
| Heckenthaler, W | 1 |
| Fasching, W | 1 |
| Scheiber, V | 1 |
| Tsukamoto, N | 2 |
| Imachi, M | 2 |
| Sumioki, H | 1 |
| Kamura, T | 2 |
| Sablińska, B | 1 |
| Bruntsch, U | 2 |
| Gallmeier, WM | 2 |
| Neville, AJ | 1 |
| Gilchrist, KW | 1 |
| Davis, TE | 2 |
| Gaminara, EJ | 1 |
| Pearson, TC | 1 |
| Greene, MH | 2 |
| Boice, JD | 2 |
| Greer, BE | 1 |
| Blessing, JA | 1 |
| Dembo, AJ | 4 |
| Schulz, U | 1 |
| Lapukins, Z | 1 |
| Bell, DR | 1 |
| Woods, RL | 1 |
| Levi, JA | 1 |
| Fox, RM | 1 |
| Tattersall, MH | 4 |
| Bush, RS | 4 |
| Dalley, VM | 1 |
| Morales, PH | 1 |
| Fayos, JV | 1 |
| Khalil, AM | 1 |
| Khatib, RA | 1 |
| Shamseddine, AI | 1 |
| Sharara, NH | 1 |
| Seoud, MA | 1 |
| Taylor, AE | 1 |
| Gore, ME | 1 |
| Green, JA | 1 |
| Robertson, LJ | 1 |
| Clark, AH | 1 |
| Powell, JL | 1 |
| Johnson, NA | 1 |
| Bailey, CL | 1 |
| Otis, CN | 1 |
| Warwick, J | 1 |
| Kehoe, S | 1 |
| Earl, H | 1 |
| Luesley, D | 3 |
| Redman, C | 1 |
| Chan, KK | 2 |
| Horton, JK | 2 |
| Piper, JT | 1 |
| Van Houten, B | 1 |
| Awasthi, YC | 1 |
| Alaoui-Jamali, MA | 1 |
| Singhal, SS | 1 |
| Roy, R | 1 |
| Denning, T | 1 |
| McCully, KS | 1 |
| Narayansingh, GV | 1 |
| Cumming, GP | 1 |
| Sarkar, TK | 1 |
| Parkin, DE | 1 |
| Wittman, MD | 1 |
| Kadow, JF | 1 |
| Vyas, DM | 1 |
| Lee, FL | 1 |
| Rose, WC | 1 |
| Long, BH | 1 |
| Fairchild, C | 1 |
| Johnston, K | 1 |
| Beale, FA | 3 |
| Bean, HA | 2 |
| Pringle, JF | 3 |
| Sturgeon, JF | 1 |
| Valdez, VA | 1 |
| Planas, AT | 1 |
| Lopez, VF | 1 |
| Goldberg, M | 1 |
| Herrera, NE | 1 |
| Akbiyik, N | 1 |
| Solisio, E | 1 |
| Alexander, L | 1 |
| Mattsson, W | 1 |
| Aspegren, K | 1 |
| Könyves, I | 1 |
| Khandekar, JD | 1 |
| Kurtides, ES | 1 |
| Stalzer, RC | 1 |
| Reimer, RR | 1 |
| Hoover, R | 1 |
| Fraumeni, JF | 1 |
| Young, RC | 1 |
| Haefliger, JM | 1 |
| Alberto, P | 2 |
| Leff, P | 1 |
| Bardsley, WG | 1 |
| Sturgeon, J | 2 |
| Reid, JG | 1 |
| Queisser, W | 1 |
| Kalb, M | 1 |
| Morrison, J | 1 |
| Yon, JL | 1 |
| Berry, RJ | 1 |
| Laing, AH | 1 |
| Wells, J | 1 |
| Brenner, S | 1 |
| Horton, J | 1 |
| Stolbach, L | 1 |
| Shnider, BI | 1 |
| Pocock, S | 1 |
| Piver, S | 1 |
| Barlow, JJ | 2 |
| Chung, WS | 1 |
| Lee, FT | 1 |
| Vongtama, V | 2 |
| Ettinger, DS | 1 |
| Parmley, TH | 1 |
| Owellen, RJ | 1 |
| Allt, WE | 1 |
| Bean, H | 1 |
| Baumgartner, G | 1 |
| Sotrel, G | 1 |
| Jafari, K | 1 |
| Lash, AF | 1 |
| Stepto, RC | 1 |
| Cannon, PM | 1 |
| Smart, CR | 1 |
| Wilson, ML | 1 |
| Edwards, CB | 1 |
| Smith, JP | 1 |
| Rutledge, F | 1 |
| Piver, MS | 2 |
| Lee, FJ | 1 |
| Swanson, CE | 1 |
| Solomon, HJ | 3 |
| Hayward, IP | 1 |
| Hurst, T | 1 |
| Parsons, PG | 2 |
| Khoo, SK | 2 |
| Rankin, EM | 1 |
| Mill, L | 2 |
| Kaye, SB | 2 |
| Atkinson, R | 1 |
| Cassidy, L | 1 |
| Cordiner, J | 1 |
| Cruickshank, D | 1 |
| Davis, J | 1 |
| Duncan, ID | 1 |
| Fullerton, W | 1 |
| Kaldor, JM | 1 |
| Day, NE | 1 |
| Pettersson, F | 1 |
| Clarke, EA | 1 |
| Pedersen, D | 1 |
| Mehnert, W | 1 |
| Bell, J | 1 |
| Høst, H | 1 |
| Prior, P | 1 |
| Karjalainen, S | 1 |
| Lawton, F | 2 |
| Blackledge, G | 3 |
| Hilton, C | 2 |
| Kelly, K | 2 |
| Latief, T | 2 |
| Mould, J | 1 |
| Spooner, D | 1 |
| Rollason, T | 2 |
| Wade-Evans, T | 2 |
| Gerding, MN | 1 |
| Blom van Assendelft, PM | 1 |
| Bosl, GJ | 1 |
| Geller, NL | 1 |
| Vogelzang, NJ | 1 |
| Carey, R | 1 |
| Auman, J | 1 |
| Whitmore, WF | 1 |
| Herr, H | 1 |
| Morse, M | 1 |
| Sogani, P | 1 |
| Chan, E | 1 |
| Goto, Y | 1 |
| Imai, K | 1 |
| Yamashita, M | 1 |
| Konishi, I | 1 |
| Fujii, S | 1 |
| Noda, Y | 1 |
| Okamura, H | 1 |
| Mori, T | 1 |
| Suzuki, A | 1 |
| Lawton, FG | 1 |
| Kelly, KA | 1 |
| Sant Cassia, LJ | 1 |
| Pippitt, CH | 1 |
| Cain, JM | 1 |
| Hakes, TB | 1 |
| Pierce, VK | 1 |
| Lewis, JL | 1 |
| Leonard, RC | 1 |
| Smart, GE | 1 |
| Livingstone, JR | 1 |
| Cornbleet, MA | 1 |
| Kerr, GR | 1 |
| Fletcher, S | 1 |
| Webb, JN | 1 |
| Smyth, JF | 1 |
| Uchino, H | 1 |
| Ono, M | 1 |
| Saito, T | 1 |
| Matsukuma, K | 1 |
| Jordan, J | 1 |
| Fielding, J | 1 |
| Maynard, K | 1 |
| Musk, P | 1 |
| Daunter, B | 1 |
| Luesley, DM | 1 |
| Newton, JR | 1 |
| Blackledge, GR | 1 |
| Harding, M | 1 |
| Kennedy, R | 1 |
| MacLean, A | 1 |
| Duncan, I | 1 |
| Kennedy, J | 1 |
| Soukop, M | 1 |
| Solomon, J | 1 |
| Ciobanu, N | 1 |
| Runowicz, C | 1 |
| Gucalp, R | 1 |
| Frank, M | 1 |
| Charuvanki, V | 1 |
| Kaufman, D | 1 |
| Wiernik, PH | 1 |
| Bennett, JM | 1 |
| Moloney, WC | 1 |
| Evans, B | 1 |
| Rustin, G | 1 |
| Gilbey, E | 1 |
| Baker, J | 1 |
| Barker, G | 1 |
| Brökelmann, J | 1 |
| Hartlapp, JH | 1 |
| Mead, GM | 2 |
| Williams, CJ | 2 |
| Whitehouse, JM | 2 |
| Mann, GJ | 1 |
| Malden, LT | 1 |
| Atkinson, KA | 1 |
| Coppleson, JV | 1 |
| Elliott, PM | 1 |
| Houghton, CR | 1 |
| Green, D | 1 |
| Russell, P | 1 |
| Bannatyne, P | 1 |
| Macbeth, FR | 1 |
| Thompson, J | 1 |
| MacDonald, H | 1 |
| Harvey, VJ | 1 |
| Slevin, ML | 1 |
| Lister, TA | 1 |
| Shepherd, JH | 1 |
| Mäenpää, J | 1 |
| Kangas, L | 1 |
| Grönroos, M | 1 |
| Pedersen-Bjergaard, J | 1 |
| Ersbøll, J | 1 |
| Sørensen, HM | 1 |
| Keiding, N | 1 |
| Larsen, SO | 1 |
| Philip, P | 1 |
| Larsen, MS | 1 |
| Schultz, H | 1 |
| Nissen, NI | 1 |
| Perez, DJ | 1 |
| Semenovskiĭ, AV | 1 |
| Copenhaver, EH | 1 |
| Abu-Rustum, S | 1 |
| Villasanta, U | 1 |
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| Speckhard, ME | 1 |
| Hurley, JD | 1 |
| Fetherston, WC | 1 |
| Grueninger, AJ | 1 |
| Moncada, R | 1 |
| Cooper, RA | 1 |
| Garces, M | 1 |
| Badrinath, K | 1 |
| Nechaeva, ID | 2 |
| Kotova, DG | 1 |
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11 reviews available for chlorambucil and Ovarian Neoplasms
| Article | Year |
|---|---|
[New trends in treatment of ovarian carcinoma (author's transl)].
Topics: Carcinoma; Chlorambucil; Cyclophosphamide; Cystadenocarcinoma; Female; Humans; Melphalan; Mesonephro | 1982 |
Management of advanced juvenile granulosa cell tumor of the ovary.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined Modality Therapy; | 1993 |
Chlorambucil.
Topics: Animals; Carcinogens; Chlorambucil; Drug Evaluation, Preclinical; Female; Fetus; Humans; Lethal Dose | 1975 |
[Chemotherapy of trophoblastic disease].
Topics: Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Cyc | 1974 |
Current cancer chemotherapy in obstetrics and gynecology.
Topics: Alkaloids; Alkylating Agents; Anti-Bacterial Agents; Antimetabolites; Blood Cell Count; Bone Marrow; | 1971 |
Guidelines for the management of patients with ovarian adenocarcinoma.
Topics: Adenocarcinoma; Castration; Chlorambucil; Cobalt Isotopes; Female; Humans; Hysterectomy; Melphalan; | 1972 |
Calcified metastases from malignant ovarian neoplasm. Review of the literature.
Topics: Abdominal Neoplasms; Adult; Aged; Axilla; Biopsy; Breast Neoplasms; Calcinosis; Chlorambucil; Cystad | 1974 |
[Combination chemotherapy in the treatment of cancer].
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Cyclophosphamide; Dacti | 1972 |
The role of chemotherapy in the treatment of primary ovarian malignancy.
Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Ascites; Chlorambucil; Chromium; DNA Repl | 1969 |
[Current status of chemotherapy of malignant tumors of the ovaries].
Topics: Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; | 1968 |
Trends in the treatment of pelvic malignant diseases.
Topics: Carcinoma; Chlorambucil; Cyclophosphamide; Female; Genital Neoplasms, Female; Humans; Hysterectomy; | 1971 |
25 trials available for chlorambucil and Ovarian Neoplasms
| Article | Year |
|---|---|
Randomised trial comparing low-dose cisplatin and chlorambucil with low-dose cisplatin, chlorambucil, and doxorubicin in advanced ovarian carcinoma.
Topics: Adenocarcinoma; Chlorambucil; Cisplatin; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combin | 1981 |
[Treatment of advanced ovarian cancer as an interdisciplinary task: surgery, histopathology, radiotherapy, and chemotherapy].
Topics: Adenocarcinoma, Mucinous; Bleomycin; Bone and Bones; Carcinoma; Chlorambucil; Cyclophosphamide; Doxo | 1983 |
[Chemotherapy of immature ovarian teratomas].
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Clinical Trials as | 1983 |
Acute nonlymphocytic leukemia after therapy with alkylating agents for ovarian cancer: a study of five randomized clinical trials.
Topics: Acute Disease; Adult; Aged; Alkylating Agents; Animals; Chlorambucil; Clinical Trials as Topic; Fema | 1982 |
Advanced ovarian cancer: a prospective randomised trial of chlorambucil versus combined cyclophosphamide and cis-diamminedichloroplatinum.
Topics: Chlorambucil; Cisplatin; Clinical Trials as Topic; Cyclophosphamide; Drug Therapy, Combination; Fema | 1982 |
Long-term follow-up of patients with advanced ovarian cancer treated in randomised clinical trials.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Combine | 1995 |
The Princess Margaret Hospital study of ovarian cancer: stages I, II, and asymptomatic III presentations.
Topics: Cell Differentiation; Chlorambucil; Clinical Trials as Topic; Female; Humans; Middle Aged; Neoplasm | 1979 |
Phase II study of Leo 1031 (prednimustine) in advanced ovarian carcinoma.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Middle Aged; O | 1979 |
Ovarian carcinoma: improved survival following abdominopelvic irradiation in patients with a completed pelvic operation.
Topics: Abdomen; Castration; Chlorambucil; Fallopian Tubes; Female; Humans; Hysterectomy; Middle Aged; Ovari | 1979 |
Comparative evaluation of combined radiation-chlorambucil treatment of ovarian carcinomatosis.
Topics: Chlorambucil; Digestive System; Evaluation Studies as Topic; Female; Humans; Leukopenia; Ovarian Neo | 1975 |
Primary treatment of advanced ovarian adenocarcinoma, stages III and IV.
Topics: Adenocarcinoma; Alkylating Agents; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Therapy, Combi | 1975 |
Advances in chemotherapy for gynecologic cancer.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug | 1975 |
Long-term survival with advanced ovarian cancer: an analysis of 5-year survivors in the Australian trial comparing combination versus sequential chlorambucil and cisplatin therapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Australia; Chlorambucil; Cisplatin; Fem | 1992 |
A randomised study comparing standard dose carboplatin with chlorambucil and carboplatin in advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Chlorambucil; Drug Adminis | 1992 |
Leukemia following chemotherapy for ovarian cancer.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Case-Control Studie | 1990 |
A randomized trial comparing whole abdominal radiotherapy with chemotherapy following cisplatinum cytoreduction in epithelial ovarian cancer. West Midlands Ovarian Cancer Group Trial II.
Topics: Abdomen; Chlorambucil; Cisplatin; Combined Modality Therapy; Female; Humans; Methods; Middle Aged; O | 1990 |
Randomised trial comparing prednimustine with combination chemotherapy in advanced ovarian carcinoma.
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clinical Trial | 1989 |
Failure of second-look laparotomy to influence survival in epithelial ovarian cancer.
Topics: Actuarial Analysis; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chlorambucil; Cisplat | 1988 |
The role of surgical reexploration following chemotherapy in ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clinical Trials as Topic; F | 1988 |
Chemotherapy of advanced ovarian adenocarcinoma: a randomized comparison of combination versus sequential therapy using chlorambucil and cisplatin.
Topics: Adenocarcinoma; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clini | 1986 |
A prospective randomized trial comparing high-dose cisplatin with low-dose cisplatin and chlorambucil in advanced ovarian carcinoma.
Topics: Actuarial Analysis; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cispl | 1986 |
Combined cyclophosphamide, adriamycin and cis-platinum in advanced ovarian cancer resistant to chlorambucil and cis-platinum.
Topics: Adenocarcinoma; Adult; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Clin | 1985 |
King George V Memorial Hospital, Sydney-Ovarian Cancer Programme (1978-1982).
Topics: Australia; Castration; Chlorambucil; Cisplatin; Clinical Trials as Topic; Combined Modality Therapy; | 1985 |
Cisplatin combination chemotherapy versus chlorambucil in advanced ovarian carcinoma: mature results of a randomized trial.
Topics: Actuarial Analysis; Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chloram | 1985 |
Effects of chlorambucil (NSC-3088) in 374 patients with advanced cancer. Eastern Clinical Drug Evualuation Program.
Topics: Carcinoma; Chlorambucil; Clinical Trials as Topic; Female; Humans; Neoplasms; Ovarian Neoplasms; Pan | 1968 |
99 other studies available for chlorambucil and Ovarian Neoplasms
| Article | Year |
|---|---|
Potent Chlorambucil-Platinum(IV) Prodrugs.
Topics: Antineoplastic Agents; Carboplatin; Cell Line, Tumor; Chlorambucil; Cisplatin; Female; Humans; Male; | 2022 |
Pharmacological tumor PDL1 depletion with chlorambucil treats ovarian cancer and melanoma: improves antitumor immunity and renders anti-PDL1-resistant tumors anti-PDL1-sensitive through NK cell effects.
Topics: Animals; B7-H1 Antigen; Chlorambucil; Female; Humans; Killer Cells, Natural; Melanoma, Experimental; | 2023 |
Floxuridine-chlorambucil conjugate nanodrugs for ovarian cancer combination chemotherapy.
Topics: Antineoplastic Agents; Chlorambucil; Drug Therapy, Combination; Female; Floxuridine; Humans; Nanopar | 2020 |
Structural modifications of mitochondria-targeted chlorambucil alter cell death mechanism but preserve MDR evasion.
Topics: Alkylating Agents; Antineoplastic Agents; Apoptosis; Cell Death; Cell Line, Tumor; Cell Nucleus; Cel | 2014 |
Gene network analysis of oxidative stress-mediated drug sensitivity in resistant ovarian carcinoma cells.
Topics: Apoptosis; Carcinoma; Cell Line, Tumor; Chlorambucil; DNA-Activated Protein Kinase; Drug Resistance, | 2010 |
Thermoresponsive chlorambucil derivatives for tumour targeting.
Topics: Antineoplastic Agents, Alkylating; Cell Line, Tumor; Chlorambucil; DNA Damage; Drug Design; Drug Scr | 2011 |
Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines.
Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorambucil; | 2012 |
CLINICAL EVALUATION OF URACIL MUSTARD.
Topics: Anemia; Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Female; Hodgkin Disease; Humans; Kidn | 1963 |
[CHEMOTHERAPY OF CANCER OF THE OVARY].
Topics: Androgens; Castration; Chlorambucil; Cobalt Isotopes; Corpus Luteum Hormones; Female; Humans; Neopla | 1963 |
EFFECTS OF IONIZING IRRADIATION AND CHEMOTHERAPEUTIC AGENTS ON HUMAN CHROMOSOMES.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Choriocarcinoma; Chromosome Aberrations; C | 1964 |
[CYTOSTATIC THERAPY].
Topics: Antineoplastic Agents; Breast Neoplasms; Busulfan; Chlorambucil; Colchicine; Cyclophosphamide; Femal | 1964 |
COMBINED TREATMENT OF DISSEMINATED OVARIAN CARCINOMA WITH COBALT TELETHERAPY AND CYTOSTATICS (CHLORAMBUCIL).
Topics: Carcinoma; Chlorambucil; Cobalt; Cobalt Isotopes; Combined Modality Therapy; Cytostatic Agents; Fema | 1964 |
TREATMENT OF NEOPLASTIC EFFUSIONS WITH CHLORAMBUCIL.
Topics: Ascites; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplasms; Pharmacology; Pleural Effusion; | 1964 |
OVARIAN DISGERMINOMA. REPORT OF A CASE TREATED WITH ACTINOMYCIN D, CHLORAMBUCIL, AND METHOTREXATE AFTER MASSIVE IRRADIATION.
Topics: Chlorambucil; Dactinomycin; Drug Therapy; Dysgerminoma; Female; Humans; Methotrexate; Neoplasms; Neo | 1964 |
EXPERIENCES WITH CHEMOTHERAPY IN GYNECOLOGIC CANCER.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Ge | 1964 |
SUSTAINED PALLIATION IN OVARIAN CARCINOMA.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Carcinoma; Chlorambucil; Dysgerminoma; Female; Gr | 1965 |
CARCINOMA OF THE OVARY.
Topics: Adenocarcinoma; Chlorambucil; Dactinomycin; Drug Therapy; Female; Humans; Lung Neoplasms; Methotrexa | 1965 |
CHLORAMBUCIL IN THE TREATMENT OF PRIMARY ADENOCARCINOMA OF THE OVARY.
Topics: Adenocarcinoma; Chlorambucil; Drug Therapy; Female; Humans; Neoplasms, Glandular and Epithelial; Ova | 1965 |
A RETROSPECTIVE COMPARISON OF CHLORAMBUCIL AND RADIOTHERAPY IN THE TREATMENT OF OVARIAN ADENOCARCINOMA.
Topics: Adenocarcinoma; Carcinoma, Ovarian Epithelial; Chlorambucil; Drug Therapy; Female; Humans; Neoplasms | 1965 |
A clinical study on the use of chlorambucil in the treatment of cancer of the ovary.
Topics: Antineoplastic Agents; Biomedical Research; Chlorambucil; Female; Humans; Neoplasms; Ovarian Neoplas | 1960 |
Combination therapy with cobalt-60 and chlorambucil in the treatment of disseminated ovarian carcinomatosis.
Topics: Carcinoma; Chlorambucil; Cobalt; Cobalt Radioisotopes; Combined Modality Therapy; Female; Humans; Me | 1962 |
Reduced DNA double strand breaks in chlorambucil resistant cells are related to high DNA-PKcs activity and low oxidative stress.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Caspases; Cell Cycle; Cell Line, Tu | 2003 |
[A phase II study of prednimustine in advanced ovarian cancer].
Topics: Aged; Chlorambucil; Drug Evaluation; Female; Humans; Middle Aged; Ovarian Neoplasms; Palliative Care | 1980 |
[Simultaneous radio-chemotherapy of advanced epithelial ovarian cancer--results after three years (author's transl)].
Topics: Adult; Aged; Antineoplastic Agents; Bleomycin; Chlorambucil; Doxorubicin; Drug Therapy, Combination; | 1981 |
[Modified VAB-3 combination chemotherapy of stage IV endodermal sinus tumor of the ovary].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; | 1984 |
[Chemotherapy of epithelial ovarian carcinoma].
Topics: Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Chlorambucil; Cisplatin; Cyc | 1983 |
The chemotherapy of granulosa cell tumors of the ovary: experience of the Wisconsin Clinical Cancer Center.
Topics: Adult; Aged; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cyclophospha | 1984 |
Chlorambucil-induced myelofibrosis.
Topics: Blood Transfusion; Chlorambucil; Female; Humans; Middle Aged; Ovarian Neoplasms; Primary Myelofibros | 1984 |
[Technic and results of radiotherapy in early stages of ovarian cancer].
Topics: Adult; Chlorambucil; Female; Humans; Methods; Middle Aged; Neoplasm Staging; Ovarian Neoplasms | 1983 |
Current concepts in cancer: ovary--treatment of stages III and IV. Choice of postoperative therapy based on prognostic factors.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Middle Aged; Ovarian Neoplasms; Prognosis; Statistics as | 1982 |
The role of radiotherapy and chemotherapy in the treatment of cancer of the ovary.
Topics: Brachytherapy; Carcinoma; Chlorambucil; Cisplatin; Cyclophosphamide; Female; Humans; Neoplasm Stagin | 1982 |
Epithelial carcinoma of the ovary.
Topics: Adolescent; Adult; Aged; Biopsy; Carcinoma; Chlorambucil; Female; Follow-Up Studies; Humans; Hystere | 1981 |
Prolonged intake of chlorambucil for ovarian cancer.
Topics: Chlorambucil; Cystadenocarcinoma; Female; Humans; Leukemia; Middle Aged; Ovarian Neoplasms | 1995 |
Chlorambucil for platinum-refractory ovarian cancer.
Topics: Adult; Aged; Carcinoma; Chlorambucil; Combined Modality Therapy; Drug Resistance; Female; Follow-Up | 1994 |
Glutathione S-transferase expression in benign and malignant ovarian tumours.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Chlorambucil; Cisplatin; Cyclopho | 1993 |
Characterization of a chlorambucil-resistant human ovarian carcinoma cell line overexpressing glutathione S-transferase mu.
Topics: Antineoplastic Agents, Alkylating; Catalysis; Cell Division; Chlorambucil; DNA Damage; Drug Resistan | 1999 |
Acquired alkylating drug resistance of a human ovarian carcinoma cell line is unaffected by altered levels of pro- and anti-apoptotic proteins.
Topics: Antineoplastic Agents, Alkylating; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Chlorambuci | 2000 |
A reappraisal of the role of chlorambucil in patients with end stage ovarian cancer who have previously been treated with platinum regimens.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Fem | 2000 |
Synthesis and antitumor activity of novel paclitaxel-chlorambucil hybrids.
Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic | 2001 |
Adenosarcoma of uterus and ovary: a clinicopathologic study of two cases.
Topics: Adult; Chlorambucil; Cyclophosphamide; Cytoplasm; Female; Humans; Middle Aged; Neoplasm Metastasis; | 1979 |
Long-term survival in a case of stage IV carcinoma of the ovary treated with a single chemotherapeutic agent.
Topics: Adenocarcinoma, Scirrhous; Adult; Chlorambucil; Cystadenoma; Female; Humans; Ovarian Neoplasms; Time | 1979 |
Acute erythroleukemia complicating prolonged chemotherapy for ovarian carcinoma.
Topics: Adult; Aged; Chlorambucil; Female; Humans; Leukemia, Erythroblastic, Acute; Long-Term Care; Ovarian | 1977 |
Acute leukemia after alkylating-agent therapy of ovarian cancer.
Topics: Acute Disease; Alkylating Agents; Altretamine; Chlorambucil; Cyclophosphamide; Female; Fluorouracil; | 1977 |
[Chemotherapy of the ovarian carcinoma (author's transl)].
Topics: Altretamine; Antineoplastic Agents; Chlorambucil; Cisplatin; Cyclophosphamide; Doxorubicin; Drug The | 1977 |
[Retrospective study of 99 cases of ovarian carcinoma, stages I to IV].
Topics: Aged; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Humans; Middle Aged; Neoplas | 1977 |
Pharmacokinetics of chlorambucil in ovarian carcinoma using a new HPLC assay.
Topics: Biotransformation; Chlorambucil; Chromatography, High Pressure Liquid; Esterification; Female; Human | 1979 |
[Secondary carcinoma: a complication of cytostatic therapy?].
Topics: Antineoplastic Agents; Breast Neoplasms; Carcinogens; Chlorambucil; Female; Humans; Immunosuppressio | 1979 |
Acute leukemia following chlorambucil therapy of advanced ovarian and fallopian tube carcinoma.
Topics: Acute Disease; Carcinoma; Chlorambucil; Fallopian Tube Neoplasms; Female; Humans; Leukemia; Middle A | 1978 |
Fresh explant culture of human tumours in vitro and the assessment of sensitivity to cytotoxic chemotherapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Chlorambucil; Culture Techniques; Drug Evaluation, Preclini | 1975 |
Endodermal sinus tumor. Report of a case with remission following chemotherapy.
Topics: Adult; Chlorambucil; Female; Humans; Ovarian Neoplasms; Remission, Spontaneous | 1977 |
Treatment of epithelial carcinoma of the ovary: operation, irradiation, and chemotherapy.
Topics: Abdomen; Castration; Chlorambucil; Cyclophosphamide; Fallopian Tubes; Female; Humans; Hysterectomy; | 1977 |
[Cytostatic therapy of inoperable carcinomas].
Topics: Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; Choriocarcinoma; Cyclophosphamide; Dactinomycin | 1976 |
Acute leukemia in advanced ovarian carcinoma after treatment with alkylating agents.
Topics: Acute Disease; Adenocarcinoma, Papillary; Adult; Alkylating Agents; Chlorambucil; Cystadenoma; Femal | 1976 |
Hypercalcemia with ovarian granulosa cell carcinoma.
Topics: Adult; Chlorambucil; Cobalt Radioisotopes; Female; Granulosa Cell Tumor; Humans; Hypercalcemia; Ovar | 1975 |
Sequential therapy for advanced ovarian adenocarcinoma: operation, chemotherapy, second-look laparotomy, and radiation therapy.
Topics: Adenocarcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Laparotomy; Melp | 1975 |
Combination chemotherapy tested in a short-term thymidine incorporation assay in primary cultures of ovarian adenocarcinomas.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosph | 1992 |
Hypokalaemia and lactic acidosis in a patient with myelomonocytic leukemia.
Topics: Acidosis, Lactic; Adenocarcinoma; Chlorambucil; Female; Humans; Hypokalemia; Leukemia, Myelomonocyti | 1990 |
Alternating cycles of etoposide plus cisplatin and VAB-6 in the treatment of poor-risk patients with germ cell tumors.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplati | 1987 |
[VAB-3 chemotherapy of endodermal sinus tumor of the ovary].
Topics: Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; | 1987 |
Speed of response to platinum-based chemotherapy: implications for the management of epithelial ovarian cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Cisplatin; Cyclophosphamide | 1987 |
Primary chemotherapy and the role of second-look laparotomy in non-dysgerminomatous germ cell malignancies of the ovary.
Topics: Adolescent; Adult; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Chlorambucil; Chorioca | 1988 |
Modified VAB-3 combination chemotherapy of advanced and recurrent endodermal sinus tumors of the ovary.
Topics: Adolescent; Adult; alpha-Fetoproteins; Antineoplastic Combined Chemotherapy Protocols; Bleomycin; Ca | 1985 |
Melphalan-resistant lymphoblastoid cell lines established from patients with ovarian cancer treated with cross-linking agents.
Topics: B-Lymphocytes; Cell Line; Cell Survival; Cell Transformation, Viral; Cells, Cultured; Chlorambucil; | 1985 |
Serial urinary cyclic guanosine monophosphate measurements in the assessment of response to treatment in epithelial ovarian cancer.
Topics: Chlorambucil; Cisplatin; Cyclic GMP; Female; Follow-Up Studies; Humans; Ovarian Neoplasms | 1987 |
A pilot study of carboplatin (JM8, CBDCA) and chlorambucil in combination for advanced ovarian cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma; Chlorambucil; F | 1988 |
Reversible central nervous system toxicity associated with high-dose chlorambucil in autologous bone marrow transplantation for ovarian carcinoma.
Topics: Adult; Bone Marrow Transplantation; Carcinoma; Chlorambucil; Dose-Response Relationship, Drug; Femal | 1987 |
Acute myeloid leukemia and other myelopathic disorders following treatment with alkylating agents.
Topics: Adolescent; Adult; Aged; Alkylating Agents; Anemia, Aplastic; Child; Child, Preschool; Chlorambucil; | 1987 |
[Chemotherapy of dysgerminoma].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Combined | 1987 |
Cisplatin, adriamycin and cyclophosphamide (PACe) combination chemotherapy in patients with ovarian carcinoma resistant to chlorambucil.
Topics: Alopecia; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Cyclophosphamide; | 1985 |
Response of ovarian cancer to combined cytotoxic agents in the subrenal capsule assay: Part I.
Topics: Aclarubicin; Adolescent; Adult; Aged; Altretamine; Animals; Antibiotics, Antineoplastic; Antineoplas | 1985 |
Risk of acute nonlymphocytic leukemia and preleukemia in patients treated with cyclophosphamide for non-Hodgkin's lymphomas. Comparison with results obtained in patients treated for Hodgkin's disease and ovarian carcinoma with other alkylating agents.
Topics: Acute Disease; Adolescent; Adult; Aged; Alkylating Agents; Antineoplastic Combined Chemotherapy Prot | 1985 |
A strategy for improved results in ovarian carcinomas: partially responsive to chemotherapy.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Cisplatin; Doxorubicin; F | 1985 |
Management of primary carcinoma of the ovary.
Topics: Adenocarcinoma, Papillary; Aged; Chlorambucil; Dactinomycin; Female; Humans; Mesonephroma; Methotrex | 1967 |
Operation, external irradiation, radioactive isotopes, and chemotherapy in treatment of metastatic ovarian malignancies.
Topics: Ascites; Carcinoma; Chlorambucil; Cyclophosphamide; Dactinomycin; Female; Fluorouracil; Follow-Up St | 1968 |
Ovarian teratomas. Relationship of histologic and ontogenic factors to prognosis.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Choriocarcinoma; Dactinomycin | 1968 |
The growth of human tumours in immunosuppressed mice and their response to chemotherapy.
Topics: Animals; Chlorambucil; Cyclophosphamide; Dactinomycin; Disease Models, Animal; Female; Fluorouracil; | 1974 |
Interdisciplinary approach to advanced ovarian cancer.
Topics: Alkylating Agents; Ascites; Chlorambucil; Dactinomycin; Drug Therapy, Combination; Female; Fluoroura | 1974 |
Single-drug therapy in ovarian cancer.
Topics: Alkylating Agents; Antineoplastic Agents; Chlorambucil; Dose-Response Relationship, Drug; Female; Hu | 1974 |
Current problems in the use of the oncolytic drugs.
Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac | 1968 |
[Apropos of an experience with the polychemotherapy of cancer].
Topics: Adult; Bone Neoplasms; Child; Chlorambucil; Cyclophosphamide; Dactinomycin; Drug Synergism; Dysgermi | 1968 |
Mixed mesodermal tumour of the uterus occurring after radiotherapy.
Topics: Aged; Chlorambucil; Cystadenoma; Female; Humans; Neoplasms, Germ Cell and Embryonal; Neoplasms, Mult | 1968 |
Integrated therapy in the treatment of ovarian cancer with surgery, radiation and chemotherapy.
Topics: Adenocarcinoma; Adenocarcinoma, Mucinous; Ascites; Chlorambucil; Cobalt Isotopes; Cyclophosphamide; | 1972 |
Tumor conference.
Topics: Adult; Carcinoma, Squamous Cell; Chlorambucil; Female; Humans; Neoplasm Metastasis; Ovarian Neoplasm | 1968 |
[Evaluation of the role of chemotherapy following radical surgery for cilioepithelial tumors of the ovaries].
Topics: Adult; Antineoplastic Agents; Carcinoma, Squamous Cell; Chlorambucil; Cyclophosphamide; Female; Huma | 1972 |
Asynchronous DNA synthesis and asynchronous mitosis in multinuclear ovarian cancer cells.
Topics: Aneuploidy; Ascitic Fluid; Autoradiography; Cell Nucleus; Chlorambucil; Cystadenocarcinoma; Cystaden | 1974 |
Peritoneal gliomatosis produced by ovarian teratomas.
Topics: Adult; Chlorambucil; Dactinomycin; Fallopian Tubes; Female; Glioma; Humans; Hysterectomy; Methotrexa | 1974 |
The value of chemotherapy in the irradiation of ovarian carcinoma.
Topics: Chlorambucil; Cobalt Isotopes; Female; Fluorouracil; Humans; Infusions, Parenteral; Injections, Intr | 1966 |
Ovarian carcinoma.
Topics: Aged; Chlorambucil; Culdoscopy; Female; Gold Isotopes; Humans; Hysterectomy; Middle Aged; Nitrogen M | 1966 |
Chemotherapy of ovarian cancer.
Topics: Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Female; Humans; Melphalan; Nitrogen Mustard C | 1967 |
[Changes in erythropoiesis in patients with malignant tumors of the ovaries during chemotherapy].
Topics: Adult; Aged; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Erythrocyte Count; Erythropoiesi | 1967 |
Cytotoxic agents in the treatment of malignant disease.
Topics: Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Carcinoma; Chlorambucil; Choriocarcinoma; | 1968 |
[Secondary tumors in hemoblastoses during cytostatic treatment].
Topics: Adrenal Gland Neoplasms; Aged; Antineoplastic Agents; Bronchial Neoplasms; Busulfan; Carcinoma; Chlo | 1971 |
[Role of chemotherapy in the treatment of malignant ovarian tumors].
Topics: Ambulatory Care; Antineoplastic Agents; Chlorambucil; Cyclophosphamide; Drug Combinations; Estrogens | 1971 |
Advanced ovarian cancer: primary treatment with surgery, radiotherapy, and chemotherapy.
Topics: Adenocarcinoma; Carcinoma; Chlorambucil; Cyclophosphamide; Female; Humans; Nitrogen Mustard Compound | 1972 |
[Antitumor polychemotherapy].
Topics: Adult; Antimetabolites; Antineoplastic Agents; Breast Neoplasms; Bronchial Neoplasms; Chlorambucil; | 1968 |
Ileo-entectropy for ascites associated with ovarian tumors.
Topics: Ascites; Ascitic Fluid; Chlorambucil; Female; Humans; Ileum; Methods; Middle Aged; Ovarian Neoplasms | 1968 |
[Treatment of ascites associated with advanced ovarian cancer].
Topics: Ascites; Carcinoma; Chlorambucil; Female; Humans; Ovarian Neoplasms | 1968 |
Sustained remissions after chemotherapy for primary ovarian cancers containing choriocarcinoma.
Topics: Adolescent; Adult; Child; Chlorambucil; Choriocarcinoma; Chorionic Gonadotropin; Dactinomycin; Dysge | 1969 |
Prophylactic use of radioactive gold in the treatment of primary ovarian cancer.
Topics: Chlorambucil; Contrast Media; Female; Gold Isotopes; Humans; Mortality; Ovarian Neoplasms; Radiograp | 1966 |