chlorambucil has been researched along with Opportunistic Infections in 9 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 52 year old woman is reported who was on long term treatment with chlorambucil and taking a short course of prednisone for familial CLL before she developed progressive dyspnoea, and P carinii pneumonia was diagnosed in bronchoalveolar lavage fluid." | 3.72 | Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia. ( Halter, J; Hechelhammer, L; Himmelmann, A; Vavricka, SR, 2004) |
| "A 4-year-old female with nephrotic syndrome secondary to focal segmental glomerulosclerosis (FSGS) was treated with pulse methylprednisolone and chlorambucil therapy." | 3.68 | Fatal Pneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis. ( Chenaille, PJ; Kano, HL; Makker, SP; Murphy, JL, 1993) |
| "A 62-year-old woman developed paresis in her right arm within several weeks." | 1.30 | [Progressive multifocal leukoencephalopathy as a result of immunosuppressive therapy]. ( Arbusow, V; Brandt, T; Brückmann, H; Hatz, H; Samtleben, W; Strupp, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eketorp Sylvan, S | 1 |
| Lundin, J | 1 |
| Ipek, M | 1 |
| Palma, M | 1 |
| Karlsson, C | 1 |
| Hansson, L | 1 |
| Bauduer, F | 1 |
| Schreiter, NF | 1 |
| Grieser, C | 1 |
| Schröder, RJ | 1 |
| Vavricka, SR | 1 |
| Halter, J | 1 |
| Hechelhammer, L | 1 |
| Himmelmann, A | 1 |
| Del Poeta, G | 1 |
| Ilaria Del Principe, M | 1 |
| Buccisano, F | 1 |
| Maurillo, L | 1 |
| Niscola, P | 1 |
| Venditti, A | 1 |
| Amadori, S | 1 |
| Hasselbach, HC | 1 |
| Fickenscher, H | 1 |
| Nölle, B | 1 |
| Roider, J | 1 |
| Murphy, JL | 1 |
| Kano, HL | 1 |
| Chenaille, PJ | 1 |
| Makker, SP | 1 |
| Arbusow, V | 1 |
| Strupp, M | 1 |
| Samtleben, W | 1 |
| Hatz, H | 1 |
| Brückmann, H | 1 |
| Brandt, T | 1 |
| Cullis, JO | 1 |
| Hyde, RD | 1 |
1 review available for chlorambucil and Opportunistic Infections
| Article | Year |
|---|---|
Role of immunochemotherapy in the treatment of chronic lymphocytic leukemia.
Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; | 2006 |
8 other studies available for chlorambucil and Opportunistic Infections
| Article | Year |
|---|---|
Alemtuzumab (anti-CD52 monoclonal antibody) as single-agent therapy in patients with relapsed/refractory chronic lymphocytic leukaemia (CLL)-a single region experience on consecutive patients.
Topics: Aged; Aged, 80 and over; Alemtuzumab; Antibodies, Monoclonal, Humanized; Antimetabolites, Antineopla | 2014 |
[First-line therapy of chronic lymphocytic leukemia in the elderly: be careful with overtreatment].
Topics: Age Factors; Aged; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodie | 2009 |
[An unusual presentation of progressive multifocal leukoencephalopathy as contrast enhanced lesion].
Topics: Aged; Antineoplastic Agents, Alkylating; Biopsy; Brain; Chlorambucil; Contrast Media; Diagnosis, Dif | 2009 |
Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia.
Topics: Anti-Infective Agents; Antineoplastic Combined Chemotherapy Protocols; Chlorambucil; Dyspnea; Fatal | 2004 |
[Atypical ocular toxoplasmosis with concomitant ocular reactivation of varicella-zoster virus and cytomegalovirus in an immunocompromised host].
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Blindness; Chlorambucil; Chorioretinitis; Como | 2008 |
Fatal Pneumocystis pneumonia in a child treated for focal segmental glomerulosclerosis.
Topics: Child, Preschool; Chlorambucil; Fatal Outcome; Female; Glomerulosclerosis, Focal Segmental; Humans; | 1993 |
[Progressive multifocal leukoencephalopathy as a result of immunosuppressive therapy].
Topics: Brain; Chlorambucil; Diagnosis, Differential; Female; Humans; Immunocompromised Host; Immunosuppress | 1999 |
Acute epiglottitis in immunocompromised patients--a report of two cases.
Topics: Acute Disease; Chlorambucil; Cyclophosphamide; Epiglottitis; Humans; Immunocompromised Host; Leukemi | 1991 |