chlorambucil has been researched along with Nephrotic Syndrome in 173 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The immunological and clinical effects of levamisole were studied in 10 children with frequently relapsing steroid responsive nephrotic syndrome (SRNS)." | 9.06 | Immunoregulation with levamisole in children with frequently relapsing steroid responsive nephrotic syndrome. ( Alon, U; Drachman, R; Drukker, A; Etzioni, A; Mor, J; Ohali, M; Schlesinger, M; Shapira, H, 1988) |
| "We evaluated the long-term effects of a five to 15-week course of chlorambucil and prednisone in 59 children with idiopathic nephrotic syndrome who had previously received prednisone alone and had had frequent relapses or steroid dependency or resistance." | 9.05 | Long-term evaluation of chlorambucil plus prednisone in the idiopathic nephrotic syndrome of childhood. ( Grupe, WE; Ingelfinger, JR; Makker, SP; Williams, SA, 1980) |
| "A controlled clinical trial was performed using two dosage regimens of chlorambucil to treat children with frequently relapsing nephrotic syndrome." | 9.04 | Chlorambucil dosage in frequently relapsing nephrotic syndrome: a controlled clinical trial. ( Baluarte, HJ; Gruskin, AB; Hiner, L, 1978) |
| "Chlorambucil, in combination with prednisone, was compared with prednisone alone in a randomized controlled trial in 21 children with either steroid-dependent or frequently relapsing nephrotic syndrome to assess its effect on the duration of remission and the rate of relapse." | 9.04 | Chlorambucil treatment of frequently relapsing nephrotic syndrome. ( Grupe, WE; Ingelfinger, JR; Makker, SP, 1976) |
| "There is now controlled evidence that a 6-month course with methylprednisolone and chlorambucil may favour remission of the nephrotic syndrome and may significantly improve the 10-year kidney survival in patients with idiopathic membranous nephropathy." | 7.73 | 20 years after methylprednisolone/chlorambucil treatment in idiopathic membranous nephropathy stage II-III with nephrotic syndrome. ( Dzikova, S; Grcevska, L; Polenakovic, M, 2006) |
| "Prednisone-resistant nephrotic syndrome (NS) due to focal segmental glomerulosclerosis (FSGS), the most common acquired disease requiring chronic dialysis and transplantation in children, has a low likelihood of response to alkylating agent therapy." | 7.69 | Intravenous methylprednisolone and oral alkylating agent therapy of prednisone-resistant pediatric focal segmental glomerulosclerosis: a long-term follow-up. ( Griswold, WR; Kirpekar, R; Mendoza, SA; Reznik, VM; Sibley, RK; Tune, BM, 1995) |
| "A 10-year old boy with steroid resistant nephrotic syndrome developed neurological symptoms during the combined therapy with Cyclosporine A, prednisone and ketonazole." | 7.69 | Neurotoxicity of Cyclosporine A in therapy of steroid resistant nephrotic syndrome in a 10-year old boy. ( Kwinta-Rybicka, J; Ogarek, I; Sancewicz-Pach, K, 1996) |
| "Eighteen patients with steroid-resistant nephrotic syndrome (SRNS) and steroid-dependent nephrotic syndrome (SDNS) were treated with cyclosporine A (CyA) (6 mg/kg/d) for 2 to 29 months." | 7.68 | Long-term cyclosporine A treatment of steroid-resistant and steroid-dependent nephrotic syndrome. ( Cohen, AH; Fine, RN; Kamil, ES; Melocoton, TL, 1991) |
| "Treatment with a combination of pulse methylprednisolone (MP) and an alkylating agent has been reported to induce long-term remission of proteinuria in patients with steroid-resistant nephrotic syndrome (SRNS)." | 7.68 | Methylprednisolone treatment of patients with steroid-resistant nephrotic syndrome. ( Benfield, MR; Kohaut, EC; Waldo, FB, 1992) |
| " We report the SCE of peripheral blood lymphocytes in children with primary nephrotic syndrome (NS) treated with chlorambucil." | 7.68 | Sister chromatid exchange analysis in monitoring chlorambucil therapy in primary nephrotic syndrome of childhood. ( al-Ali, M; al-Nassar, K; Elsharie, F; Elzouki, AY; Jaiswal, OP; Malik, G, 1991) |
| "Mechlorethamine has been assessed in 28 patients with idiopathic nephrotic syndrome previously treated with prednisone only." | 7.67 | [Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood]. ( Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL, 1984) |
| "Chlorambucil (CHL) was used in combination with prednisolone in the treatment of nine children with frequently relapsing nephrotic syndrome." | 7.67 | Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome. ( Asada, R; Ichida, F; Konda, M; Konishi, T; Kyotani, S; Okada, T; Suzuki, Y; Tani, M; Tanizawa, T; Yamatani, M, 1985) |
| "Patients with prednisone-resistant nephrotic syndrome and biopsy-proven focal segmental glomerulosclerosis were treated with intravenous methylprednisone." | 7.67 | Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents. ( Brock, P; Griswold, WR; Mendoza, SA; Prime, DJ; Reznik, VM; Tune, BM; Vazquez, M, 1987) |
| " The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy." | 7.67 | Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984) |
| "Five patients with a steroid-responsive, frequently relapsing nephrotic syndrome who had failed at least one course of treatment with cyclophosphamide were all put into a long term remission with chlorambucil." | 7.67 | Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide. ( Bailey, RR, 1989) |
| "To assess the gonadal effects of chlorambucil given to prepubertal and pubertal boys, testicular function of 21 adolescents or young men, treated with chlorambucil for nephrotic syndrome before or during puberty, have been evaluated." | 7.66 | Gonadal effects of chlorambucil given to prepubertal and pubertal boys for nephrotic syndrome. ( Broyer, M; Guesry, P; Lenoir, G, 1978) |
| "Chlorambucil (Leukeran), a cytotoxic agent, was administered to 13 children with the nephrotic syndrome who had responded to steroid therapy, but frequently relapsed." | 7.66 | Chlorambucil therapy in childhood nephrotic syndrome. ( McDonald, R; van Dugteren, GR; Wiggelinkhuizen, J, 1979) |
| "Twenty-six preadolescent children ( 16 boys and 10 girls) with minimal lesion nephrotic syndrome, who were either unresponsive to or dependent on corticosteroid therapy, were treated exclusively with chlorambucil." | 7.66 | Chlorambucil treatment in minimal lesion nephrotic syndrome: a reappraisal of its gonadal toxicity. ( Callis, L; Nieto, J; Rende, J; Vila, A, 1980) |
| "The therapy of nephrotic syndrome in focal segmental glomerulosclerosis (FSGS) is still a matter of controversy." | 6.71 | Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis. ( Braun, N; Fünfstück, R; Grabensee, B; Heering, P; Ivens, K; Keller, F; Krämer, BK; Müllejans, R; Risler, T; Schollmeyer, P; Zäuner, I, 2004) |
| " To explore this uncertainty, a meta-analysis of controlled trials of treatment with cyclophosphamide or chlorambucil was performed in patients with idiopathic membranous nephropathy and nephrotic-range proteinuria." | 6.17 | Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials. ( Berns, JS; Goldfarb, S; Imperiale, TF, 1995) |
| "This observational study aimed to evaluate the results of treatment with low-dose chlorambucil in combination with corticosteroids in patients with idiopathic membranous nephropathy (iMGN) and nephrotic syndrome." | 5.14 | Efficacy and safety of low-dose chlorambucil in nephrotic patients with idiopathic membranous nephropathy. ( Idasiak-Piechocka, I; Oko, A; Skrobańska, B; Łochyńska-Bielecka, K, 2009) |
| "To validate the hypothesis that the 2 treatments were equivalent, patients with biopsy-proven membranous nephropathy and nephrotic syndrome were randomly assigned to methylprednisolone alternated with a cytotoxic drug every other month for 6 months (group A) or to intramuscular synthetic adrenocorticotropic hormone administered twice a week for 1 year (group B)." | 5.12 | A randomized pilot trial comparing methylprednisolone plus a cytotoxic agent versus synthetic adrenocorticotropic hormone in idiopathic membranous nephropathy. ( Mandolfo, S; Manno, C; Messa, P; Pasquali, S; Passerini, P; Ponticelli, C; Salvadori, M; Viola, BF, 2006) |
| "In order to elucidate long-term effects of immunosuppressants, we studied 60 children with steroid-dependent nephrotic syndrome who were treated with three immunosuppressants: cyclophosphamide (n=34), chlorambucil (n=11), and cyclosporin A (n=15)." | 5.08 | Long-term effects of immunosuppressants in steroid-dependent nephrotic syndrome. ( Matsutani, H; Niimura, F; Ohgushi, H; Takeda, A, 1998) |
| "Two Italian controlled trials demonstrated that the difference in remission rates obtained with six months of methylprednisolone and chlorambucil (MP+Ch) compared to MP was smaller than MP+Ch versus symptomatic therapy in the treatment of idiopathic membranous nephropathy nephrotic syndrome (NS)." | 5.07 | Therapy for idiopathic membranous nephropathy: tailoring the choice by decision analysis. ( Passerini, P; Piccoli, A; Pillon, L; Ponticelli, C, 1994) |
| "In patients with the nephrotic syndrome caused by idiopathic membranous nephropathy, treatment with methylprednisolone and chlorambucil for six months induces an earlier remission of the nephrotic syndrome than methylprednisolone alone, but the difference may diminish with time." | 5.07 | Methylprednisolone plus chlorambucil as compared with methylprednisolone alone for the treatment of idiopathic membranous nephropathy. The Italian Idiopathic Membranous Nephropathy Treatment Study Group. ( Cesana, B; Passerini, P; Ponticelli, C; Zucchelli, P, 1992) |
| "Twenty-five adult patients with idiopathic membranous nephropathy (IMN) and nephrotic syndrome (NS) who had participated at a long-term randomized trial with steroid and chlorambucil for six months, underwent repeated renal biopsies." | 5.06 | Clinical and morphologic evolution of idiopathic membranous nephropathy. ( Cagnoli, L; Casanova, S; Donini, U; Pasquali, S; Zucchelli, P, 1986) |
| "The immunological and clinical effects of levamisole were studied in 10 children with frequently relapsing steroid responsive nephrotic syndrome (SRNS)." | 5.06 | Immunoregulation with levamisole in children with frequently relapsing steroid responsive nephrotic syndrome. ( Alon, U; Drachman, R; Drukker, A; Etzioni, A; Mor, J; Ohali, M; Schlesinger, M; Shapira, H, 1988) |
| "Sixty-seven adults with idiopathic membranous nephropathy and the nephrotic syndrome were randomly assigned to symptomatic treatment only or to a six-month course of methylprednisolone alternated with chlorambucil every other month." | 5.05 | Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy. ( Cagnoli, L; Grassi, C; Imbasciati, E; Limido, D; Pasquali, S; Passerini, P; Ponticelli, C; Pozzi, C; Volpini, T; Zucchelli, P, 1984) |
| "In a prospective, controlled study, 50 children with frequently relapsing nephrotic syndrome who had steroid toxicity were treated for eight weeks with either cyclophosphamide (2 mg per kilogram of body weight per day) or chlorambucil (0." | 5.05 | Effect of cytotoxic drugs in frequently relapsing nephrotic syndrome with and without steroid dependence. ( , 1982) |
| "A controlled clinical trial was performed using two dosage regimens of chlorambucil to treat children with frequently relapsing nephrotic syndrome." | 5.04 | Chlorambucil dosage in frequently relapsing nephrotic syndrome: a controlled clinical trial. ( Baluarte, HJ; Gruskin, AB; Hiner, L, 1978) |
| "Chlorambucil, in combination with prednisone, was compared with prednisone alone in a randomized controlled trial in 21 children with either steroid-dependent or frequently relapsing nephrotic syndrome to assess its effect on the duration of remission and the rate of relapse." | 5.04 | Chlorambucil treatment of frequently relapsing nephrotic syndrome. ( Grupe, WE; Ingelfinger, JR; Makker, SP, 1976) |
| "For over 30 years cyclophosphamide (CYC) and chlorambucil (CHL) have been used to treat children with relapsing steroid-sensitive nephrotic syndrome (SSNS)." | 4.81 | A meta-analysis of cytotoxic treatment for frequently relapsing nephrotic syndrome in children. ( Ehrich, JH; Latta, K; von Schnakenburg, C, 2001) |
| " Cyclophosphamide with or without chlorambucil resolved steroid-dependency in 33 of 46 (72%) children who either had complete remission or developed steroid-sensitive, rather than steroid-dependent, nephrotic syndrome." | 3.76 | Treatment course of steroid-dependent nephrotic syndrome: emphasized on treatment effect. ( Chen, SY; Tsai, IJ; Tsau, YK; Wu, CY, 2010) |
| "There is now controlled evidence that a 6-month course with methylprednisolone and chlorambucil may favour remission of the nephrotic syndrome and may significantly improve the 10-year kidney survival in patients with idiopathic membranous nephropathy." | 3.73 | 20 years after methylprednisolone/chlorambucil treatment in idiopathic membranous nephropathy stage II-III with nephrotic syndrome. ( Dzikova, S; Grcevska, L; Polenakovic, M, 2006) |
| "Prednisone-resistant nephrotic syndrome (NS) due to focal segmental glomerulosclerosis (FSGS), the most common acquired disease requiring chronic dialysis and transplantation in children, has a low likelihood of response to alkylating agent therapy." | 3.69 | Intravenous methylprednisolone and oral alkylating agent therapy of prednisone-resistant pediatric focal segmental glomerulosclerosis: a long-term follow-up. ( Griswold, WR; Kirpekar, R; Mendoza, SA; Reznik, VM; Sibley, RK; Tune, BM, 1995) |
| "A 10-year old boy with steroid resistant nephrotic syndrome developed neurological symptoms during the combined therapy with Cyclosporine A, prednisone and ketonazole." | 3.69 | Neurotoxicity of Cyclosporine A in therapy of steroid resistant nephrotic syndrome in a 10-year old boy. ( Kwinta-Rybicka, J; Ogarek, I; Sancewicz-Pach, K, 1996) |
| "Treatment with a combination of pulse methylprednisolone (MP) and an alkylating agent has been reported to induce long-term remission of proteinuria in patients with steroid-resistant nephrotic syndrome (SRNS)." | 3.68 | Methylprednisolone treatment of patients with steroid-resistant nephrotic syndrome. ( Benfield, MR; Kohaut, EC; Waldo, FB, 1992) |
| "Eighteen patients with steroid-resistant nephrotic syndrome (SRNS) and steroid-dependent nephrotic syndrome (SDNS) were treated with cyclosporine A (CyA) (6 mg/kg/d) for 2 to 29 months." | 3.68 | Long-term cyclosporine A treatment of steroid-resistant and steroid-dependent nephrotic syndrome. ( Cohen, AH; Fine, RN; Kamil, ES; Melocoton, TL, 1991) |
| "A prospective study was performed in order to evaluate the efficacy of oral cyclophosphamide and chlorambucil in inducing a remission in children with steroid-resistant primary nephrotic syndrome (NS)." | 3.68 | Long-term follow-up in children with steroid-resistant nephrotic syndrome. ( Bakkaloglu, A; Besbas, N; Saatci, O; Topaloglu, R, 1992) |
| "Patients with prednisone-resistant nephrotic syndrome and biopsy-proven focal segmental glomerulosclerosis were treated with intravenous methylprednisone." | 3.67 | Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents. ( Brock, P; Griswold, WR; Mendoza, SA; Prime, DJ; Reznik, VM; Tune, BM; Vazquez, M, 1987) |
| " Forty of them, who presented a nephrotic syndrome, were treated by immunosuppressive drugs (prednisone, azathioprine, chlorambucil, cyclophosphamide) for 79 +/- 9." | 3.67 | Long-term immunosuppressive therapy of idiopathic membranoproliferative glomerulonephritis. ( Glyda, J; Gradowska, L; Juskowa, J; Klepacka, J; Lao, M; Morzycka-Michalik, M; Orlowski, T; Rancewicz, Z, 1988) |
| "Mechlorethamine has been assessed in 28 patients with idiopathic nephrotic syndrome previously treated with prednisone only." | 3.67 | [Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood]. ( Canals, MJ; Cervera, A; Gómez Campderá, FJ; Gómez Campderá, J; López Gómez, JM; Luque, A; Morales, JL, 1984) |
| "Chlorambucil (CHL) was used in combination with prednisolone in the treatment of nine children with frequently relapsing nephrotic syndrome." | 3.67 | Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome. ( Asada, R; Ichida, F; Konda, M; Konishi, T; Kyotani, S; Okada, T; Suzuki, Y; Tani, M; Tanizawa, T; Yamatani, M, 1985) |
| "Growth velocity measurements were assessed in 12 children with steroid responsive but frequent relapsing or dependent nephrotic syndrome prior to and following treatment with either cyclophosphamide or chlorambucil and alternate day prednisone." | 3.67 | Linear growth of children with nephrotic syndrome: effect of alkylating agents. ( Brem, AS; Padilla, R, 1989) |
| "Five patients with a steroid-responsive, frequently relapsing nephrotic syndrome who had failed at least one course of treatment with cyclophosphamide were all put into a long term remission with chlorambucil." | 3.67 | Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide. ( Bailey, RR, 1989) |
| " The heavy proteinuria exhibited a striking steroid-dependent course during a three-year period of time, with ten relapses occurring whenever attempts were made to withdraw prednisone therapy." | 3.67 | Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil. ( Abuelo, JG; Esparza, AR; Garella, S, 1984) |
| "Chlorambucil neurotoxicity was observed in two children treated for frequently relapsing minimal change nephrotic syndrome." | 3.66 | Chlorambucil neurotoxicity: report of two cases. ( Ammenti, A; Müller-Wiefel, DE; Reitter, B, 1980) |
| "To assess the gonadal effects of chlorambucil given to prepubertal and pubertal boys, testicular function of 21 adolescents or young men, treated with chlorambucil for nephrotic syndrome before or during puberty, have been evaluated." | 3.66 | Gonadal effects of chlorambucil given to prepubertal and pubertal boys for nephrotic syndrome. ( Broyer, M; Guesry, P; Lenoir, G, 1978) |
| "The therapy of nephrotic syndrome in focal segmental glomerulosclerosis (FSGS) is still a matter of controversy." | 2.71 | Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis. ( Braun, N; Fünfstück, R; Grabensee, B; Heering, P; Ivens, K; Keller, F; Krämer, BK; Müllejans, R; Risler, T; Schollmeyer, P; Zäuner, I, 2004) |
| "Patients with biopsy-proven membranous nephropathy and with a nephrotic syndrome were randomized to be given methylprednisolone (1 g intravenously for 3 consecutive days followed by oral methylprednisolone, 0." | 2.69 | A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy. ( Altieri, P; Antonucci, F; Bellazzi, R; Cesana, B; Dugo, M; Farina, M; Grassi, C; Lupo, A; Melis, P; Minari, M; Pasquali, S; Passerini, P; Pedrini, L; Piccoli, G; Pisano, G; Ponticelli, C; Pozzi, C; Roccatello, D; Sasdelli, M; Scalia, A; Scolari, F; Segagni, S; Valzorio, B, 1998) |
| " Long-term follow-up trials focused on gonadal toxicity and limitation of maximum dosage of cyclophosphamide should been carried out." | 2.61 | Efficacy and acceptability of immunosuppressive agents for pediatric frequently-relapsing and steroid-dependent nephrotic syndrome: A network meta-analysis of randomized controlled trials. ( Li, Q; Li, S; Tan, L; Wan, J; Yang, H; Zou, Q, 2019) |
| "Those with nephrotic syndrome are usually treated with steroids initially and often followed by alkylating agents (cyclophosphamide or chlorambucil)." | 2.46 | Membranous nephropathy in children: clinical presentation and therapeutic approach. ( Menon, S; Valentini, RP, 2010) |
| "Persistent hyperlipidemia increases the risk of cardiovascular diseases." | 2.42 | [Membranous nephropathy]. ( Godin, M; Legallicier, B; Passos, EM, 2003) |
| "Membranous nephropathy is the most common histologic phenotype associated with the primary nephrotic syndrome in adults and the second most common etiological diagnosis in over sixteen hundred renal biopsies on native kidneys processed at our institution over a 30 year period." | 2.42 | [Membranous kidney diseases in adults]. ( Sobarzo Toro, M; Vilches, A, 2004) |
| "The best treatment of idiopathic membranous nephropathy remains an area of clinical controversy." | 2.41 | Treatment of idiopathic membranous nephropathy (IMN). ( Alexopoulos, E; Papagianni, A, 2000) |
| "Approximately 30% of children with focal segmental glomerulosclerosis enter remission following treatment with corticosteroids." | 2.38 | Immunosuppressive therapy in the nephrotic syndrome in children. ( Trompeter, RS, 1989) |
| "There is no definite treatment for focal glomerulosclerosis." | 2.38 | Treatment of the nephrotic syndrome with cyclosporin A. ( Ponticelli, C, 1992) |
| "Patients with nephrotic syndrome are in a constant state of flux with respect to fluid status, organ function, and critical protein balance." | 2.38 | Pharmacologic management of adult idiopathic nephrotic syndrome. ( Alaniz, C; Brosius, FC; Palmieri, J, 1993) |
| "Children with systemic lupus erythematosus and nephritis may benefit from the addition of cytotoxic agents to their corticosteroid regime, although the indications for this are not clear, and controlled evidence is lacking." | 2.36 | Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children. ( Cameron, JS, 1979) |
| "Juvenile idiopathic arthritis was diagnosed and kidney biopsy examination showed mesangial glomerulonephritis with immunoglobulin M deposits." | 1.39 | Nephrotic syndrome due to immunoglobulin M mesangial glomerulonephritis preceding juvenile idiopathic arthritis. ( Alvarado, C; Balestracci, A; Cuttica, RJ; Lago, N; Voyer, LE; Zardini, M, 2013) |
| " Information on dosage of prednisolone and immunosuppressive agents was also analyzed." | 1.33 | Follow-up of linear growth of body height in children with nephrotic syndrome. ( Hung, YT; Yang, LY, 2006) |
| "Although nondiabetic nephropathies are common among type 2 diabetic patients, very few cases of minimal change nephrotic syndrome have been reported in diabetic patients." | 1.32 | [Relapsing nephrotic syndrome in a diabetic patient with minimal change]. ( Espejo, B; García Donaire, JA; Gutiérrez Martínez, E; Manzanera, MI; Praga, M; Valentín, MO, 2004) |
| "Levamisole was given to 7 patients with concomitant respiratory infection." | 1.31 | [The effect of treatment methods on frequency of relapse in nephrotic syndrome in children]. ( Bochniewska, V; Goszczyk, A; Jung, A; Straz-Zebrowska, E, 2000) |
| " Gender, age at onset, duration of illness from onset, prednisolone dosage at the most-recent relapse, and regimens of initial steroid therapy at onset were not associated with risk." | 1.31 | Prediction of subsequent relapse in children with steroid-sensitive nephrotic syndrome. ( Mizusawa, Y; Simoda, M; Takeda, A; Takimoto, H, 2001) |
| "A further recurrence of the nephrotic syndrome responded well to a short course of chlorambucil (cumulative dose 420 mg) and of prednisone with slow dose reduction." | 1.29 | [T-cell lymphoma under immunosuppressive treatment in minimal change glomerulopathy with nephrotic syndrome]. ( Schollmeyer, P; Späth, M, 1995) |
| "Levamisole was given to 56 children (13%) and cyclosporin to 53 (12%)." | 1.29 | Alternative treatment to corticosteroids in steroid sensitive idiopathic nephrotic syndrome. ( Barratt, TM; Dillon, MJ; Fay, J; Neuhaus, TJ; Trompeter, RS, 1994) |
| "Nephrotic syndrome was observed in nine patients." | 1.28 | Glomerulonephritis in chronic lymphocytic leukemia and related B-cell lymphomas. ( Fillastre, JP; Francois, A; Mignon, F; Mougenot, B; Moulin, B; Ronco, PM, 1992) |
| "Proteinuria was reduced in all eight, from a mean (SD) of 15." | 1.27 | Prednisolone and chlorambucil treatment in idiopathic membranous nephropathy with deteriorating renal function. ( Evans, DJ; Maidment, CG; Mathieson, PW; Rees, AJ; Turner, AN, 1988) |
| "Nephrotic syndrome is steroid-responsive in the majority of children." | 1.26 | Childhood nephrotic syndrome: clinical associations and response to therapy. ( Grupe, WE, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 108 (62.43) | 18.7374 |
| 1990's | 35 (20.23) | 18.2507 |
| 2000's | 24 (13.87) | 29.6817 |
| 2010's | 5 (2.89) | 24.3611 |
| 2020's | 1 (0.58) | 2.80 |
| Authors | Studies |
|---|---|
| Larkins, NG | 1 |
| Liu, ID | 1 |
| Willis, NS | 5 |
| Craig, JC | 5 |
| Hodson, EM | 5 |
| Tan, L | 1 |
| Li, S | 1 |
| Yang, H | 1 |
| Zou, Q | 1 |
| Wan, J | 1 |
| Li, Q | 1 |
| Voyer, LE | 1 |
| Alvarado, C | 1 |
| Cuttica, RJ | 1 |
| Balestracci, A | 1 |
| Zardini, M | 1 |
| Lago, N | 1 |
| Pravitsitthikul, N | 1 |
| Kniazewska, MH | 1 |
| Obuchowicz, AK | 1 |
| Wielkoszyński, T | 1 |
| Zmudzińska-Kitczak, J | 1 |
| Urban, K | 1 |
| Hyla-Klekot, L | 1 |
| Idasiak-Piechocka, I | 1 |
| Oko, A | 1 |
| Łochyńska-Bielecka, K | 1 |
| Skrobańska, B | 1 |
| Donatti, TL | 1 |
| Koch, VH | 1 |
| Menon, S | 1 |
| Valentini, RP | 1 |
| Chen, SY | 1 |
| Wu, CY | 1 |
| Tsai, IJ | 1 |
| Tsau, YK | 1 |
| Sakai, H | 1 |
| Kurokawa, K | 1 |
| Saito, T | 1 |
| Shiiki, H | 1 |
| Nishi, S | 1 |
| Mitarai, T | 1 |
| Yokoyama, H | 1 |
| Yoshimura, A | 1 |
| Yorioka, N | 1 |
| BARIETY, J | 5 |
| LAGRUE, G | 5 |
| SAFAR, M | 1 |
| HESSE, JC | 1 |
| MILLIEZ, P | 3 |
| Heering, P | 1 |
| Braun, N | 1 |
| Müllejans, R | 1 |
| Ivens, K | 1 |
| Zäuner, I | 1 |
| Fünfstück, R | 1 |
| Keller, F | 1 |
| Krämer, BK | 1 |
| Schollmeyer, P | 2 |
| Risler, T | 1 |
| Grabensee, B | 1 |
| Passos, EM | 1 |
| Legallicier, B | 1 |
| Godin, M | 2 |
| Sobarzo Toro, M | 1 |
| Vilches, A | 1 |
| García Donaire, JA | 1 |
| Manzanera, MI | 1 |
| Valentín, MO | 1 |
| Espejo, B | 1 |
| Gutiérrez Martínez, E | 1 |
| Praga, M | 2 |
| Durkan, A | 2 |
| Bodaghi, E | 1 |
| Chamsa, AM | 1 |
| Rüth, EM | 1 |
| Kemper, MJ | 1 |
| Leumann, EP | 1 |
| Laube, GF | 1 |
| Neuhaus, TJ | 2 |
| Ponticelli, C | 11 |
| Passerini, P | 7 |
| Salvadori, M | 1 |
| Manno, C | 1 |
| Viola, BF | 1 |
| Pasquali, S | 5 |
| Mandolfo, S | 1 |
| Messa, P | 1 |
| Kari, JA | 1 |
| Alkushi, A | 1 |
| Alshaya, HO | 1 |
| Hung, YT | 1 |
| Yang, LY | 1 |
| Polenakovic, M | 1 |
| Grcevska, L | 1 |
| Dzikova, S | 1 |
| Hattori, M | 1 |
| Zosin, C | 2 |
| Mănescu, N | 2 |
| Schwarzkopf, A | 2 |
| Adams, DA | 1 |
| Gordon, A | 1 |
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| Zucchelli, P | 6 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| ADRENL - ACTHAR Gel for Drug REsistant Nephrotic Syndrome in Children, Pilot Study[NCT03408405] | Phase 4 | 0 participants (Actual) | Interventional | 2018-06-30 | Withdrawn (stopped due to Withdrawal of funding from primary sponsor) | ||
| Clinical Study of Rituximab or Cyclophosphamide Combined With Steroids in the Treatment of Idiopathic Membranous Nephropathy[NCT05514015] | Phase 4 | 72 participants (Anticipated) | Interventional | 2022-08-25 | Not yet recruiting | ||
| Ofatumumab in Children With Steroid- and Calcineurin-inhibitor-resistant Nephrotic Syndrome: a Double-blind Randomized, Controlled, Superiority Trial[NCT02394106] | Phase 2 | 13 participants (Actual) | Interventional | 2015-07-31 | Terminated | ||
| Ofatumumab Versus Rituximab in Children With Steroid and Calcineurin Inhibitor-dependent Idiopathic Nephrotic Syndrome: an Open-label, Randomized, Controlled, Superiority Trial.[NCT02394119] | Phase 2 | 140 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| Random, Open, Control and Monocentric Clinical Research on Tacrolimus Monotherapy for Idiopathic Membranous Nephropathy (IMN)[NCT03549663] | 108 participants (Anticipated) | Interventional | 2018-07-04 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
31 reviews available for chlorambucil and Nephrotic Syndrome
| Article | Year |
|---|---|
Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
Topics: Adolescent; Alkylating Agents; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosphamide | 2020 |
Efficacy and acceptability of immunosuppressive agents for pediatric frequently-relapsing and steroid-dependent nephrotic syndrome: A network meta-analysis of randomized controlled trials.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporine; Dru | 2019 |
Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporine; Hum | 2013 |
Membranous nephropathy in children: clinical presentation and therapeutic approach.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biopsy; Child; Chlorambucil; Cycl | 2010 |
[Guidelines for the management of refractory nephrotic syndrome--from investigations between 1997 and 2001--research project team for progressive renal lesions in the Ministry of Health, Labor and Welfare, Japan].
Topics: Blood Component Removal; Cause of Death; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; D | 2002 |
[Membranous nephropathy].
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Basement Membrane; Child; Child, Preschool; Chlorambuci | 2003 |
[Membranous kidney diseases in adults].
Topics: Adrenal Cortex Hormones; Adult; Chlorambucil; Cyclophosphamide; Cyclosporine; Glomerulonephritis, Me | 2004 |
Non-corticosteroid treatment for nephrotic syndrome in children.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Humans; Immunosuppressive Agent | 2005 |
Non-corticosteroid treatment for nephrotic syndrome in children.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporine; Hum | 2008 |
[Treatment of nephrotic syndrome in children (author's transl)].
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Humans; Nephrotic Syndrome; Recurren | 1980 |
Mesangial IgM nephropathy.
Topics: Chlorambucil; Cyclophosphamide; Humans; Immunoglobulin M; Kidney Glomerulus; Nephrotic Syndrome; Ste | 1983 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Nephrotic syndrome in childhood. Management and treatment in patients with minimal change disease, mesangial proliferation, or focal glomerulosclerosis.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Diuretics; Female; Glomerulonep | 1982 |
Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials.
Topics: Chlorambucil; Cyclophosphamide; Glomerulonephritis, Membranous; Humans; Kidney; Nephrotic Syndrome; | 1995 |
Primary nephrotic syndrome in the elderly.
Topics: Actuarial Analysis; Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Aged; Chlorambucil; Female; | 1993 |
Pharmacologic management of adult idiopathic nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Chlorambucil; Cyclosporine; Drug Therapy, Combination; Edema; Glomeruloneph | 1993 |
Treatment of idiopathic membranous nephropathy (IMN).
Topics: Antineoplastic Agents, Alkylating; Chlorambucil; Cyclosporine; Glomerulonephritis, Membranous; Gluco | 2000 |
Immunosuppressive agents in childhood nephrotic syndrome: a meta-analysis of randomized controlled trials.
Topics: Adolescent; Adrenal Cortex Hormones; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclos | 2001 |
A meta-analysis of cytotoxic treatment for frequently relapsing nephrotic syndrome in children.
Topics: Antineoplastic Agents, Alkylating; Child; Chlorambucil; Cyclophosphamide; Humans; Nephrotic Syndrome | 2001 |
Non-corticosteroid treatment for nephrotic syndrome in children.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Humans; Immunosuppressive Agent | 2001 |
Primary nephrotic syndrome in childhood.
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Edema; Hospitalization; Humans; Immunization; I | 1979 |
[Haematuria in children. III. Treatment of glomerular diseases (author's transl)].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Glomerulonephri | 1978 |
Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children.
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive A | 1979 |
Treatment of the nephrotic syndrome with cyclosporin A.
Topics: Chlorambucil; Cyclophosphamide; Cyclosporine; Glomerulonephritis, Membranous; Glomerulosclerosis, Fo | 1992 |
Immunosuppressive therapy in the nephrotic syndrome in children.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporins; Glom | 1989 |
Cytotoxic drugs in treatment of nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Chlor | 1972 |
[Prognosis of the idiopathic nephrotic syndrome in children].
Topics: Adrenocorticotropic Hormone; Biopsy; Blood Proteins; Chlorambucil; Cyclophosphamide; Female; Humans; | 1974 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
[Immunosuppressive therapy of the nephrotic syndrome in childhood].
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Cystitis; Drug Resistance; Humans; Immunosuppre | 1972 |
Drug therapy. Immunosuppressive agents. I.
Topics: Adrenal Cortex Hormones; Adult; Alkylating Agents; Antimetabolites; Arthritis, Rheumatoid; Autoimmun | 1973 |
Management of the nephrotic syndrome.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos | 1974 |
[Nephrotic syndrome in childhood].
Topics: Adolescent; Age Factors; Azathioprine; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphami | 1974 |
26 trials available for chlorambucil and Nephrotic Syndrome
| Article | Year |
|---|---|
Efficacy and safety of low-dose chlorambucil in nephrotic patients with idiopathic membranous nephropathy.
Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Female; Follow-Up | 2009 |
Cyclosporine A and chlorambucil in the treatment of idiopathic focal segmental glomerulosclerosis.
Topics: Adult; Aged; Alkylating Agents; Biopsy; Chlorambucil; Cyclosporine; Drug Therapy, Combination; Femal | 2004 |
A randomized pilot trial comparing methylprednisolone plus a cytotoxic agent versus synthetic adrenocorticotropic hormone in idiopathic membranous nephropathy.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Antineoplastic Agents, Alkylating; Chlorambucil; Cyclophos | 2006 |
Controlled trial of monthly alternated courses of steroid and chlorambucil for idiopathic membranous nephropathy.
Topics: Chlorambucil; Clinical Trials as Topic; Creatinine; Drug Administration Schedule; Drug Therapy, Comb | 1983 |
Controlled trial of methylprednisolone and chlorambucil in idiopathic membranous nephropathy.
Topics: Adult; Aged; Chlorambucil; Clinical Trials as Topic; Creatinine; Drug Administration Schedule; Femal | 1984 |
Irreversible renal failure after indomethacin in steroid-resistant nephrosis.
Topics: Child; Chlorambucil; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Humans; Indometha | 1980 |
Long-term evaluation of chlorambucil plus prednisone in the idiopathic nephrotic syndrome of childhood.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Drug Therapy, Combinati | 1980 |
Effect of cytotoxic drugs in frequently relapsing nephrotic syndrome with and without steroid dependence.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Femal | 1982 |
Are cytotoxic agents beneficial in idiopathic membranous nephropathy? A meta-analysis of the controlled trials.
Topics: Chlorambucil; Cyclophosphamide; Glomerulonephritis, Membranous; Humans; Kidney; Nephrotic Syndrome; | 1995 |
Therapy for idiopathic membranous nephropathy: tailoring the choice by decision analysis.
Topics: Adolescent; Adult; Aged; Chlorambucil; Decision Support Techniques; Drug Therapy, Combination; Femal | 1994 |
[Verification of indications for kidney biopsy in children with steroid-dependent nephrotic syndrome].
Topics: Anti-Inflammatory Agents; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclospor | 1996 |
HLA-DR7 predicts the response to alkylating agents in steroid-sensitive nephrotic syndrome.
Topics: Adolescent; Age of Onset; Alkylating Agents; Anti-Inflammatory Agents; Child; Child, Preschool; Chlo | 1997 |
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu | 1998 |
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu | 1998 |
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu | 1998 |
A randomized study comparing methylprednisolone plus chlorambucil versus methylprednisolone plus cyclophosphamide in idiopathic membranous nephropathy.
Topics: Adolescent; Adult; Aged; Amenorrhea; Anemia; Antineoplastic Agents, Alkylating; Carcinoma; Chlorambu | 1998 |
Long-term effects of immunosuppressants in steroid-dependent nephrotic syndrome.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Chlorambucil; Cyclophosphamide | 1998 |
Controlled trial of chlorambucil in frequently relapsing nephrotic syndrome in children (a preliminary report).
Topics: Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Double-Blind Method; Female; Humans | 1978 |
Chlorambucil dosage in frequently relapsing nephrotic syndrome: a controlled clinical trial.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Humans; Nephrotic Syndrome; Recurrence; Remission | 1978 |
Chlorambucil treatment of frequently relapsing nephrotic syndrome.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Chlorambucil; Drug Evaluation; Drug Therapy, Combi | 1976 |
Comparison of cyclosporin and chlorambucil in the treatment of steroid-dependent idiopathic nephrotic syndrome: a multicentre randomized controlled trial. The French Society of Paediatric Nephrology.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Creatinine; Cyclosporine; Drug Administration Sch | 1992 |
Methylprednisolone plus chlorambucil as compared with methylprednisolone alone for the treatment of idiopathic membranous nephropathy. The Italian Idiopathic Membranous Nephropathy Treatment Study Group.
Topics: Adolescent; Adult; Aged; Chlorambucil; Drug Administration Schedule; Drug Therapy, Combination; Fema | 1992 |
[Evaluation of the effectiveness of various programs of active therapy of primary glomerulonephritis with nephrotic syndrome in children].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Drug Administration Schedule; Drug Therapy, Combi | 1991 |
Prognostic value of T lymphocyte subset ratio in idiopathic membranous nephropathy.
Topics: Adult; Antibodies, Monoclonal; Chlorambucil; Humans; Methylprednisolone; Middle Aged; Nephrotic Synd | 1988 |
Immunoregulation with levamisole in children with frequently relapsing steroid responsive nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Femal | 1988 |
The advantages of immunosuppressive therapy in renal disease.
Topics: Chlorambucil; Clinical Trials as Topic; Follow-Up Studies; Glomerulonephritis; Humans; Immunosuppres | 1988 |
Clinical and morphologic evolution of idiopathic membranous nephropathy.
Topics: Adolescent; Adult; Aged; Basement Membrane; Biopsy; Chlorambucil; Clinical Trials as Topic; Female; | 1986 |
Immunosuppressive therapy. 2.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Adult; Azathioprine; Child; Chlorambucil; Clin | 1972 |
Management of the nephrotic syndrome.
Topics: Adolescent; Azathioprine; Child; Child, Preschool; Chlorambucil; Clinical Trials as Topic; Cyclophos | 1974 |
119 other studies available for chlorambucil and Nephrotic Syndrome
| Article | Year |
|---|---|
Nephrotic syndrome due to immunoglobulin M mesangial glomerulonephritis preceding juvenile idiopathic arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Biopsy; Child, Preschool; Chlorambucil; Glomeruloneph | 2013 |
Evaluation of certain constituents of antioxidant defense in youth treated in the past for steroid-sensitive idiopathic nephrotic syndrome.
Topics: Adolescent; Anthropometry; Antioxidants; Aryldialkylphosphatase; Ascorbic Acid; Case-Control Studies | 2009 |
Final height of adults with childhood-onset steroid-responsive idiopathic nephrotic syndrome.
Topics: Body Height; Child; Child Development; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporin | 2009 |
Treatment course of steroid-dependent nephrotic syndrome: emphasized on treatment effect.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporine; Female; Glucocort | 2010 |
[THE NEPHROTIC SYNDROME OF "RHEUMATOID PURPURA"].
Topics: Abdomen; Abdomen, Acute; Abdominal Cavity; Child; Chlorambucil; Diagnosis; Glomerulonephritis; Hemat | 1964 |
[Relapsing nephrotic syndrome in a diabetic patient with minimal change].
Topics: Chlorambucil; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diagnosis, Differential; Drug Thera | 2004 |
[Primary nephrotic syndromes in children in Iran].
Topics: Adolescent; Anti-Inflammatory Agents; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphamid | 1978 |
Children with steroid-sensitive nephrotic syndrome come of age: long-term outcome.
Topics: Adrenal Cortex Hormones; Adult; Antineoplastic Agents, Alkylating; Child, Preschool; Chlorambucil; C | 2005 |
Chlorambucil therapy in children with steroid-resistant nephrotic syndrome.
Topics: Antineoplastic Agents, Alkylating; Child; Child, Preschool; Chlorambucil; Female; Humans; Nephrotic | 2006 |
Follow-up of linear growth of body height in children with nephrotic syndrome.
Topics: Adolescent; Body Height; Child; Child Development; Child, Preschool; Chlorambucil; Cohort Studies; C | 2006 |
20 years after methylprednisolone/chlorambucil treatment in idiopathic membranous nephropathy stage II-III with nephrotic syndrome.
Topics: Adult; Chlorambucil; Drug Therapy, Combination; Female; Follow-Up Studies; Glomerulonephritis, Membr | 2006 |
[Recent advances in therapy for nephrotic syndrome in children].
Topics: Anti-Inflammatory Agents; Azathioprine; Child; Chlorambucil; Cyclophosphamide; Drug Administration S | 2007 |
[The treatment of the nephrotic syndrome with the aid of immunosuppressive drugs].
Topics: Chlorambucil; Glomerulonephritis; Humans; Immunosuppressive Agents; Nephrotic Syndrome; Prednisone | 1967 |
Azathioprine treatment of immunological renal disease.
Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Cortisone; Female; Glomerulonephritis; Humans; Lupus | 1967 |
A patient with IgA GN with steroid-dependent nephrotic syndrome.
Topics: Chlorambucil; Glomerulonephritis; Humans; Immunoglobulin A; Male; Methylprednisolone; Middle Aged; N | 1984 |
[Effect of mechlorethamine in idiopathic nephrotic syndrome in childhood].
Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Tolerance; Female; Glomerulosclerosis, | 1984 |
Steroid-dependent nephrotic syndrome in lupus nephritis. Response to chlorambucil.
Topics: Adult; Chlorambucil; Female; Glomerulonephritis; Humans; Lupus Erythematosus, Systemic; Nephrotic Sy | 1984 |
[Neurotoxicity of chlorambucil--2 cases of nephrotic syndrome with abnormal EEG].
Topics: Adolescent; Child; Chlorambucil; Electroencephalography; Humans; Male; Nephrotic Syndrome | 1983 |
Renal pathology of Waldenström's macroglobulinaemia with monoclonal antiglomerular antibodies and nephrotic syndrome.
Topics: Aged; Autoantibodies; Chlorambucil; Humans; Immunoglobulin M; Kidney; Kidney Glomerulus; Male; Nephr | 1980 |
Acute leukemia after cytotoxic treatment for nonmalignant disease in childhood. A case report and review of the literature.
Topics: Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Cytarabine; Humans; Leukemia, Lymphoid | 1981 |
Treatment of nephrotic syndrome with levamisole.
Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Female; Follow-Up Studies; Humans; Levamiso | 1980 |
Treatment of the idiopathic nephrotic syndrome.
Topics: Alkylating Agents; Child; Chlorambucil; Cyclophosphamide; Drug Resistance; Glomerulonephritis; Human | 1981 |
Immune deposits and mesangial hypercellularity in minimal change nephrotic syndrome: clinical relevance.
Topics: Adolescent; Biopsy; Child; Child, Preschool; Chlorambucil; Complement C3; Complement C4; Cyclophosph | 1982 |
Cytotoxic drugs for nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Alkylating Agents; Antineoplastic Agents; Child; Chlorambucil; Humans; Neph | 1982 |
Primary glomerular disease: to treat or not to treat.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulonephritis; Glomerulosclerosis, | 1982 |
Therapy for the child with nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Cyclophosphamide; Humans; Mechlorethamine; Nephrotic S | 1982 |
Multiple relapsing steroid responsive nephrosis treated with chlorambucil.
Topics: Adult; Chlorambucil; Drug Therapy, Combination; Humans; Male; Nephrotic Syndrome; Prednisone; Recurr | 1982 |
Long-term assessment of chlorambucil in children with nephrotic syndrome who fail to respond adequately to corticosteroids.
Topics: Adolescent; Anemia; Bacterial Infections; Child; Child, Preschool; Chlorambucil; Drug Resistance; Fe | 1981 |
Chlorambucil for childhood nephrosis: a word of caution.
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Humans; Nephrotic Syndrome; Recurrence | 1980 |
Cytotoxic treatment in children with idiopathic nephrotic syndrome.
Topics: Adolescent; Antineoplastic Agents; Child; Chlorambucil; Cyclophosphamide; Follow-Up Studies; Humans; | 1980 |
Chlorambucil neurotoxicity: report of two cases.
Topics: Adolescent; Child, Preschool; Chlorambucil; Electroencephalography; Female; Humans; Myoclonus; Nephr | 1980 |
Chlorambucil treatment in minimal lesion nephrotic syndrome: a reappraisal of its gonadal toxicity.
Topics: Adolescent; Adult; Chlorambucil; Female; Humans; Male; Nephrotic Syndrome; Sex Characteristics; Sexu | 1980 |
[T-cell lymphoma under immunosuppressive treatment in minimal change glomerulopathy with nephrotic syndrome].
Topics: Adult; Chlorambucil; Cyclosporins; Female; Humans; Immunosuppressive Agents; Lymphoma, T-Cell; Nephr | 1995 |
Alternative treatment to corticosteroids in steroid sensitive idiopathic nephrotic syndrome.
Topics: Adrenal Cortex Hormones; Child; Child, Preschool; Chlorambucil; Chloramphenicol; Cyclophosphamide; C | 1994 |
Intravenous methylprednisolone and oral alkylating agent therapy of prednisone-resistant pediatric focal segmental glomerulosclerosis: a long-term follow-up.
Topics: Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Administration Schedule; Drug Resistance; Dru | 1995 |
In what order should one introduce cyclophosphamide or chlorambucil, cyclosporine or levamisole in a child with steroid-dependent frequently relapsing nephrotic syndrome?
Topics: Child; Chlorambucil; Cyclophosphamide; Cyclosporine; Drug Administration Schedule; Glucocorticoids; | 1993 |
[Therapeutic approach to steroid resistant idiopathic nephrotic syndrome in childhood].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Child; Chlorambucil; Cyclophosphamide; Drug Resistance; | 1995 |
Neurotoxicity of Cyclosporine A in therapy of steroid resistant nephrotic syndrome in a 10-year old boy.
Topics: Brain Diseases; Child; Chlorambucil; Cyclophosphamide; Cyclosporine; Drug Resistance; Drug Therapy, | 1996 |
[Remote effect of Tripterygium wilfordii and chlorambucil on the function of sex glands of child with nephropathy].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Drugs, Chinese Herbal; Female; Follicle Stimulati | 1996 |
Complete remission of nephrotic syndrome after steroid-chlorambucil in a previous failed short-term steroidal treatment of a primary membranous nephropathy.
Topics: Adult; Antineoplastic Agents, Alkylating; Chlorambucil; Follow-Up Studies; Glomerulonephritis, Membr | 1996 |
Mesenteric arterial thrombosis complicating the nephrotic syndrome.
Topics: Adult; Anti-Inflammatory Agents; Antineoplastic Agents, Alkylating; Chlorambucil; Glomerulonephritis | 1997 |
Treatment of membranous lupus nephritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Chlorambucil; Drug Evaluation; Drug Therapy, Combination | 1998 |
Should cyclosporine replace cytoxan or chlorambucil as the second-line drug for steroid-dependent nephrotic syndrome?
Topics: Child; Chlorambucil; Cyclophosphamide; Cyclosporine; Glucocorticoids; Humans; Immunosuppressive Agen | 1998 |
Retroperitoneal fibrosis and membranous nephropathy. Improvement of both diseases after treatment with steroids and immunosuppressive agents.
Topics: Anti-Inflammatory Agents; Chlorambucil; Drug Therapy, Combination; Glomerulonephritis, Membranous; H | 1999 |
Chlorambucil-induced seizure in a patient with nephrotic syndrome.
Topics: Adult; Chlorambucil; Glomerulonephritis, Membranous; Humans; Male; Nephrotic Syndrome; Seizures | 1999 |
The patient with over 100 relapses of minimal change nephrotic syndrome: prolonged complete remission after chlorambucil treatment.
Topics: Adult; Blood Pressure; Chlorambucil; Disease-Free Survival; Humans; Male; Nephrotic Syndrome; Recurr | 2000 |
Nephrotic syndrome associated with Kimura disease.
Topics: Adolescent; Angiolymphoid Hyperplasia with Eosinophilia; Anti-Inflammatory Agents; Antineoplastic Ag | 2000 |
[The effect of treatment methods on frequency of relapse in nephrotic syndrome in children].
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chlorambucil; Female; Follow-Up Studies; | 2000 |
Prediction of subsequent relapse in children with steroid-sensitive nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporine; Drug Therapy, Com | 2001 |
Immunosuppression in the nephrotic syndrome.
Topics: Adult; Aged; Child; Chlorambucil; Cyclophosphamide; Drug Evaluation; Humans; Nephrotic Syndrome | 1976 |
[Acute myeloid leukemia following chlorambucil administration. 2 observations].
Topics: Arthritis, Rheumatoid; Chlorambucil; Female; Humans; Leukemia, Myeloid, Acute; Middle Aged; Nephroti | 1978 |
[Acute myeloid leukemia occurring after nephrotic syndrome treated with leukeran].
Topics: Child; Chlorambucil; Female; Humans; Leukemia, Myeloid, Acute; Nephrotic Syndrome | 1979 |
Childhood nephrotic syndrome: clinical associations and response to therapy.
Topics: Child; Chlorambucil; Cyclophosphamide; Female; Humans; Male; Nephrotic Syndrome; Prednisone; Prognos | 1979 |
Chromosome mutations and chromosome stability in children treated with different regimes of immunosuppressive drugs.
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorambucil; Chromatids; Chromosome Aberrations; Cyclop | 1979 |
[Clinical course and recurrences of the nephrotic syndrome due to minimal histologic lesions. Review of 73 cases (author's transl)].
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Chlorambucil; Drug Therapy, Combination; Fe | 1979 |
Chlorambucil therapy in childhood nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Female; Follow-Up Studies; Humans; Male; Nephroti | 1979 |
Remission of idiopathic nephrotic syndrome in three Oahu children: a four and one-half year follow-up.
Topics: Adolescent; Chlorambucil; Female; Follow-Up Studies; Humans; Male; Nephrotic Syndrome; Prednisone; R | 1979 |
Gonadal effects of chlorambucil given to prepubertal and pubertal boys for nephrotic syndrome.
Topics: Adolescent; Cell Count; Child; Chlorambucil; Follicle Stimulating Hormone; Humans; Luteinizing Hormo | 1978 |
[Use of leukeran in the treatment of nephrotic syndrome in children].
Topics: Adolescent; Child; Chlorambucil; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male; N | 1978 |
[Experiences with cytotoxic drugs in therapy of the nephrotic syndrome].
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Huma | 1977 |
[Extragonadal complications of chlorambucil in children. Report of 300 cases of glomerulonephritis].
Topics: Adolescent; Adult; Child; Child, Preschool; Chlorambucil; France; Glomerulonephritis; Hematologic Di | 1977 |
Editorial: Four plus: the management of nephrosis.
Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Drug Tolerance; Glomerulonephritis; Humans; Nephrosis; | 1976 |
[Treatment of nephrotic syndrome of children with immunosuppressive agents (literature survey)].
Topics: Age Factors; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Evaluation; | 1975 |
[Immunosuppressive therapy in familial nephrotic syndrome].
Topics: Chlorambucil; Cyclophosphamide; Humans; Immunosuppressive Agents; Infant; Male; Nephrotic Syndrome; | 1975 |
[Should adult nephrotic syndrome secondary to idiopathic extramembranous glomerulonephritis be treated? An approach by decisional analysis].
Topics: Adrenal Cortex Hormones; Chlorambucil; Glomerulonephritis; Humans; Nephrotic Syndrome | 1992 |
Methylprednisolone treatment of patients with steroid-resistant nephrotic syndrome.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chlorambucil; Drug Administration Schedul | 1992 |
Controlled, multi-center trials are needed in pediatric nephrology.
Topics: Chlorambucil; Glomerulosclerosis, Focal Segmental; Humans; Methylprednisolone; Multicenter Studies a | 1992 |
How to manage a child with steroid-responsive nephrotic syndrome when dose of prednisolone is reduced or when placed on high-dose alternate day steroids.
Topics: Child, Preschool; Chlorambucil; Cyclophosphamide; Female; Humans; Nephrotic Syndrome; Prednisolone; | 1992 |
Long-term follow-up in children with steroid-resistant nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resistance; Female; Follow | 1992 |
Glomerulonephritis in chronic lymphocytic leukemia and related B-cell lymphomas.
Topics: Adult; Aged; Aged, 80 and over; B-Lymphocytes; Chlorambucil; Female; Glomerulonephritis; Glomerulone | 1992 |
Membranous nephropathy--still a treatment dilemma.
Topics: Adult; Chlorambucil; Drug Therapy, Combination; Glomerulonephritis, Membranous; Humans; Methylpredni | 1992 |
[Results of the treatment of glomerulonephritis in children with hepatitis B].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resistance; D | 1991 |
Long-term cyclosporine A treatment of steroid-resistant and steroid-dependent nephrotic syndrome.
Topics: Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Cyclosporine; Female; Humans; Kidne | 1991 |
Sister chromatid exchange analysis in monitoring chlorambucil therapy in primary nephrotic syndrome of childhood.
Topics: Child; Child, Preschool; Chlorambucil; Female; Humans; Infant; Male; Nephrotic Syndrome; Sister Chro | 1991 |
Linear growth of children with nephrotic syndrome: effect of alkylating agents.
Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Female; Growth; Humans; Infant; Kidney; Mal | 1989 |
Remission induced by chlorambucil in steroid-responsive, frequently relapsing nephrotic syndrome that relapsed after cyclophosphamide.
Topics: Administration, Oral; Child; Chlorambucil; Cyclophosphamide; Drug Administration Schedule; Drug Eval | 1989 |
Prednisolone and chlorambucil treatment in idiopathic membranous nephropathy with deteriorating renal function.
Topics: Adult; Chlorambucil; Drug Administration Schedule; Drug Evaluation; Female; Follow-Up Studies; Glome | 1988 |
Relapsing nephrotic syndrome.
Topics: Captopril; Chlorambucil; Cyclophosphamide; Cyclosporins; Glomerular Mesangium; Humans; Immune Comple | 1987 |
Long-term immunosuppressive therapy of idiopathic membranoproliferative glomerulonephritis.
Topics: Adult; Azathioprine; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Female; Follow-Up St | 1988 |
Clinical regression of amyloid nephropathy in a patient with rheumatoid arthritis. A case report.
Topics: Adult; Amyloidosis; Arthritis, Rheumatoid; Chlorambucil; Female; Humans; Nephrotic Syndrome; Remissi | 1988 |
Treatment of idiopathic membranous nephropathy unresponsive to methylprednisolone and chlorambucil with cyclosporin.
Topics: Adult; Chlorambucil; Cyclosporins; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; | 1987 |
Treatment of childhood prednisone-resistant nephrotic syndrome and focal segmental glomerulosclerosis with intravenous methylprednisolone and oral alkylating agents.
Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resi | 1987 |
[Juvenile nephrotic syndrome with diffuse mesangial sclerosis. Apropos of a case report].
Topics: Child, Preschool; Chlorambucil; Female; Glomerular Mesangium; Humans; Kidney Failure, Chronic; Nephr | 1986 |
Nephrotic syndrome in two patients with cured Hodgkin's disease.
Topics: Adult; Chlorambucil; Gallium Radioisotopes; Hodgkin Disease; Humans; Male; Nephrosis, Lipoid; Nephro | 1985 |
Chlorambucil central nervous toxicity: a significant side effect of chlorambucil therapy in childhood nephrotic syndrome.
Topics: Brain; Central Nervous System Diseases; Child; Chlorambucil; Drug Therapy, Combination; Electroencep | 1985 |
Combined prednisolone, azathioprine, and cyclophosphamide treatment for persistent proliferative glomerulonephritis in adults.
Topics: Adolescent; Adult; Azathioprine; Chlorambucil; Cholesterol; Creatinine; Cyclophosphamide; Female; Gl | 1971 |
Chlorambucil in steroid-dependent nephrotic syndrome.
Topics: Adolescent; Beta-Globulins; Blood Pressure; Child; Child, Preschool; Chlorambucil; Drug Synergism; F | 1973 |
[Atypical measles with giant cell pneumonia under treatment with chlorambucil (author's transl)].
Topics: Child, Preschool; Chlorambucil; Female; Humans; Immunologic Deficiency Syndromes; Measles; Nephrotic | 1972 |
Editorial: Focal glomerular sclerosis.
Topics: Chlorambucil; Complement Fixation Tests; Complement System Proteins; Eosinophils; Female; Fibrin; Hu | 1973 |
Immunosuppressive treatment of nephrotic syndrome.
Topics: Adolescent; Adult; Aged; Amyloidosis; Azathioprine; Biopsy; Blood Proteins; Chlorambucil; Dactinomyc | 1969 |
Nephrotic syndrome in chronic lymphocytic leukaemia.
Topics: Aged; Basement Membrane; Biopsy; Blood Proteins; Bone Marrow; Chlorambucil; Complement System Protei | 1974 |
[Therapy of the nephrotic syndrome].
Topics: Adrenocorticotropic Hormone; Azathioprine; Chlorambucil; Chlorthalidone; Diet, Sodium-Restricted; Di | 1968 |
[Course of nephropathy in systemic lupus erythematosus . Influence of the treatment on clinical symptoms, renal function and histology].
Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Antimalarials; Azathioprine; Biopsy; Chlorambucil; | 1972 |
[Nephropathies of rheumatoid purpura in children. Clinical and anatomical study of 60 cases].
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Diagnosis, Differential; Female; Fluorescent Anti | 1972 |
Nephrosis of Hodgkin disease. An immune complex-induced lesion.
Topics: Antigen-Antibody Complex; Basement Membrane; Biopsy; Blood Urea Nitrogen; Body Weight; Capillaries; | 1973 |
[Papillary edema spontaneously curable during a treatment with chlorambucil].
Topics: Child; Chlorambucil; Drug Tolerance; Female; Humans; Nephrotic Syndrome; Papilledema; Pseudotumor Ce | 1972 |
Chlorambucil in steroid-dependent nephrotic syndrome.
Topics: Animals; Child; Chlorambucil; Cyclophosphamide; Female; Fertility; Guinea Pigs; Humans; Infertility, | 1973 |
[Results of immunosuppressive treatment of nephrotic syndrome].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Biopsy; Chlorambucil; Cyclophosphamide; Female; Humans; | 1973 |
[Childhood nephrotic syndrome with minimun glomerular lesions (clinical development and therapeutic response in 40 cases)].
Topics: Adolescent; Azathioprine; Biopsy; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Female; H | 1973 |
Letter: Chlorambucil or cyclophosphamide in treatment of nephrosis.
Topics: Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Gonads; Humans; Nephrotic Syndrome | 1974 |
The idiopathic nephrotic syndrome of childhood. A clinical reevaluation of 148 cases.
Topics: Adolescent; Antistreptolysin; Azathioprine; Bacteriuria; Blood Urea Nitrogen; Child; Child, Preschoo | 1974 |
Long-term follow-up of cyclophosphamide therapy in frequent relapsing minimal lesion nephrotic syndrome.
Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resistance; Follow-Up Stud | 1974 |
[Recovery of normal ultrastructure in 2 cases of primary glomerulonephritis with diffuse extra-membranous deposits].
Topics: Adult; Basement Membrane; Biopsy; Chlorambucil; Female; Glomerulonephritis; Glucocorticoids; Hematur | 1968 |
[Prognosis of the idiopathic nephrotic syndrome in childhood by means of plasma protein clearance].
Topics: Age Factors; Azathioprine; Blood Proteins; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; | 1969 |
[Subacute sclerosing panencephalitis appearing during nephrotic syndrome treated with immunosuppressive agents].
Topics: Cerebrospinal Fluid Proteins; Child, Preschool; Chlorambucil; Electroencephalography; Humans; Immuno | 1971 |
[Immunodepressive therapy in nephropathies].
Topics: Azathioprine; Chlorambucil; Collagen Diseases; Diabetic Nephropathies; Glomerulonephritis; Humans; I | 1969 |
[Immunosuppressive treatment of corticoid resistant nephrotic syndrome in childhood].
Topics: Azathioprine; Child; Child, Preschool; Chlorambucil; Dexamethasone; Female; Humans; Male; Nephrosis, | 1969 |
[Correlations between the histological changes and results of treatment with corticoids and immunosuppressive agents in primary glomerulonephritis].
Topics: Adrenal Cortex Hormones; Alkylating Agents; Azathioprine; Chlorambucil; Glomerulonephritis; Humans; | 1970 |
Cold agglutinin disease and the nephrotic syndrome.
Topics: Aged; Anemia, Hemolytic; Autopsy; Bone Marrow; Chlorambucil; Coombs Test; Cryoglobulins; Female; Hum | 1970 |
[Primary glomerulopathies--therapy using corticosteroids and cytostatics (immunosuppressive agents)].
Topics: Antineoplastic Agents; Azathioprine; Chlorambucil; Glomerulonephritis; Humans; Immunosuppressive Age | 1970 |
Chronic lymphocytic leukemia, Hodgkin's disease, and the nephrotic syndrome.
Topics: Blood Protein Electrophoresis; Chlorambucil; Cobalt Isotopes; Electrophoresis; Female; Hodgkin Disea | 1968 |
[Cytostatic treatment of the steroid-resistant nephrotic syndrome. (Long term study on 24 patients)].
Topics: Adult; Azathioprine; Biopsy; Chlorambucil; Female; Glomerulonephritis; Humans; Kidney Function Tests | 1968 |
[Attempt at treatment of idiopathic nephrotic syndrome in children by brief cortisone therapy eventually alternated with an immunodepressor therapy].
Topics: Adolescent; Age Factors; Child; Child, Preschool; Chlorambucil; Drug Synergism; Female; Humans; Male | 1968 |
[Immunosuppresive agents in the treatment of nephropathies of children].
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Humans; Immunosuppressive Agents; Kidney Diseas | 1969 |
[Attempts of the use of cytostatic agents in some forms of glomerulonephritis in children].
Topics: Adolescent; Antineoplastic Agents; Azathioprine; Child; Child, Preschool; Chlorambucil; Chronic Dise | 1969 |
[Chlorambucil in the treatment of idiopathic nephrotic syndrome without glomrular lesions in childhood. Apropos of 30 cases].
Topics: Adolescent; Anemia; Biopsy; Child; Child, Preschool; Chlorambucil; Female; Glucocorticoids; Humans; | 1969 |
[Hemolytic and uremic syndrome associated with an idiopathic nephrotic syndrome of 4 years' development].
Topics: Anemia, Hemolytic; Biopsy; Child; Chlorambucil; Female; Glucocorticoids; Hemoglobinuria; Humans; Hyp | 1969 |
[Extended chemotherapy of nephrotic syndromes and of certain glomerular nephropathies].
Topics: Chlorambucil; Glomerulonephritis; Humans; Mechlorethamine; Nephrotic Syndrome | 1965 |
Cytotoxic drugs in steroid-resistant renal disease. Alkylating and antimetabolic agents in the treatment of nephrotic syndrome, lupus nephritis, chronic glomerulonephritis, and purpura nephritis in children.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosp | 1966 |