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chlorambucil and Nephrosis

chlorambucil has been researched along with Nephrosis in 7 studies

Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.

Nephrosis: Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA.

Research Excerpts

ExcerptRelevanceReference
"The chlorambucil dosage was 0."5.28Evaluation of chlorambucil therapy in steroid-dependent and cyclophosphamide-resistant children with nephrosis. ( Elzouki, AY; Jaiswal, OP, 1990)
"The chlorambucil dosage was 0."1.28Evaluation of chlorambucil therapy in steroid-dependent and cyclophosphamide-resistant children with nephrosis. ( Elzouki, AY; Jaiswal, OP, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kleinknecht, C3
Broyer, M3
Gubler, MC1
Palcoux, JB1
Jarde, O1
Guillot, M1
Guesry, P1
Lenoir, G1
Coggins, CH1
Elzouki, AY1
Jaiswal, OP1
Steinberg, AD1
Schwalbová, M1
Krajci-Lazáryová, M1
Misíková, Z1

Reviews

1 review available for chlorambucil and Nephrosis

ArticleYear
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
    The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; G

1973

Trials

1 trial available for chlorambucil and Nephrosis

ArticleYear
Irreversible renal failure after indomethacin in steroid-resistant nephrosis.
    The New England journal of medicine, 1980, Mar-20, Volume: 302, Issue:12

    Topics: Child; Chlorambucil; Clinical Trials as Topic; Female; Glomerular Filtration Rate; Humans; Indometha

1980

Other Studies

5 other studies available for chlorambucil and Nephrosis

ArticleYear
Treatment of the idiopathic nephrotic syndrome.
    Paediatrician, 1981, Volume: 10, Issue:5-6

    Topics: Alkylating Agents; Child; Chlorambucil; Cyclophosphamide; Drug Resistance; Glomerulonephritis; Human

1981
High-cost benefit of chlorambucil in frequently relapsing nephrosis.
    The New England journal of medicine, 1977, 01-06, Volume: 296, Issue:1

    Topics: Adolescent; Child; Chlorambucil; Humans; Male; Nephrosis; Testis

1977
Editorial: Four plus: the management of nephrosis.
    The New England journal of medicine, 1976, Sep-30, Volume: 295, Issue:14

    Topics: Adrenal Cortex Hormones; Child; Chlorambucil; Drug Tolerance; Glomerulonephritis; Humans; Nephrosis;

1976
Evaluation of chlorambucil therapy in steroid-dependent and cyclophosphamide-resistant children with nephrosis.
    Pediatric nephrology (Berlin, Germany), 1990, Volume: 4, Issue:5

    Topics: Adolescent; Child; Child, Preschool; Chlorambucil; Cyclophosphamide; Drug Resistance; Female; Humans

1990
[Immunosuppresive agents in the treatment of nephropathies of children].
    Bratislavske lekarske listy, 1969, Volume: 51, Issue:2

    Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Humans; Immunosuppressive Agents; Kidney Diseas

1969