chlorambucil has been researched along with Nephritis in 11 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Nephritis: Inflammation of any part of the KIDNEY.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 7.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 3.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| "Children with systemic lupus erythematosus and nephritis may benefit from the addition of cytotoxic agents to their corticosteroid regime, although the indications for this are not clear, and controlled evidence is lacking." | 2.36 | Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children. ( Cameron, JS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Donadio, JV | 1 |
| Stepanova, NS | 1 |
| Solov'ev, SK | 1 |
| Kaĭnova, AS | 1 |
| Ivanova, MM | 1 |
| Cameron, JS | 1 |
| Schambelan, M | 1 |
| Kampf, D | 1 |
| Baethke, R | 1 |
| Tareeva, IE | 1 |
| Filimonova, RG | 1 |
| Poliantseva, LR | 1 |
| Mukhin, NA | 1 |
| Steinberg, AD | 1 |
| Snaith, ML | 2 |
| Holt, JM | 2 |
| Oliver, DO | 2 |
| Dunnill, MS | 1 |
| Halley, W | 1 |
| Stephenson, AC | 1 |
| Stephenson, A | 1 |
| Grupe, WE | 1 |
| Heymann, W | 1 |
3 reviews available for chlorambucil and Nephritis
| Article | Year |
|---|---|
Immunosuppressive agents in the treatment of the nephrotic syndrome and glomerulonephritis in children.
Topics: Azathioprine; Child; Chlorambucil; Cyclophosphamide; Glomerulonephritis; Humans; Immunosuppressive A | 1979 |
[Therapy of lupus-nephritis using corticosteroids and immunosuppressive agents].
Topics: Adrenal Cortex Hormones; Antibodies, Antinuclear; Azathioprine; Beta-Globulins; Chlorambucil; Cyclop | 1974 |
An approach to the use of immunosuppressive drugs in nonmalignant diseases.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chlorambucil; Cyclophosphamide; G | 1973 |
8 other studies available for chlorambucil and Nephritis
| Article | Year |
|---|---|
Primary glomerular disease: to treat or not to treat.
Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Dipyridamole; Glomerulonephritis; Glomerulosclerosis, | 1982 |
[Effect of cytotoxic immunosuppressive agents on the level of urinary seromucoids and cathepsins in lupus nephritis].
Topics: Azathioprine; Cathepsins; Chlorambucil; Cyclophosphamide; Drug Therapy, Combination; Humans; Immunos | 1980 |
The treatment of the nephritis of lupus erythematosus.
Topics: Adult; Chlorambucil; Female; Glucocorticoids; Humans; Lupus Erythematosus, Systemic; Nephritis | 1977 |
Letter: Hyporeninemic hypoaldosteronism in chronic renal disease.
Topics: Aldosterone; Chlorambucil; Chronic Disease; Female; Humans; Hypopituitarism; Nephritis; Prednisone; | 1975 |
[Treatment of chronic nephritis with cytostatics].
Topics: Adolescent; Adult; Antineoplastic Agents; Azathioprine; Chlorambucil; Chronic Disease; Cyclophospham | 1974 |
Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil.
Topics: Adult; Alopecia; Amenorrhea; Azathioprine; Biopsy; Bone Marrow; Chlorambucil; Cyclophosphamide; Cyst | 1973 |
Successful treatment of patients with systemic lupus erythematosus, including nephritis, using chlorambucil.
Topics: Chlorambucil; Female; Humans; Lupus Erythematosus, Systemic; Nephritis; Proteinuria | 1973 |
Cytotoxic drugs in steroid-resistant renal disease. Alkylating and antimetabolic agents in the treatment of nephrotic syndrome, lupus nephritis, chronic glomerulonephritis, and purpura nephritis in children.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Child; Child, Preschool; Chlorambucil; Cyclophosp | 1966 |